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The map label for this gene is tkt [H]

Identifier: 119716767

GI number: 119716767

Start: 2709976

End: 2712120

Strand: Reverse

Name: tkt [H]

Synonym: Noca_2541

Alternate gene names: 119716767

Gene position: 2712120-2709976 (Counterclockwise)

Preceding gene: 119716769

Following gene: 119716766

Centisome position: 54.4

GC content: 71.61

Gene sequence:

>2145_bases
GTGGCCGATGACCTCGAAAGGAATCCTGTGACCGACACCGCTGCGCTCGACTGGACCGACCTCGACCAGAAGGCGGTGGA
CACGGCCCGAGTGCTCGCGATGGACGCGGTGCAGAAGGTCGGCAACGGCCACCCGGGCACGGCGATGAGCCTGGCCCCCG
CGGCGTACCTGCTGTTCCAGAAGGTGATGCGCCACGACCCGTCCGACCCGCGCTGGATCGCGCGGGACCGGTTCGTCCTC
TCGGCGGGTCACTCCTCGCTCACCCTGTACATCCAGCTCTTCCTCGGCGGCTTCGGGCTCGAGCTCGACGACCTCAAGGC
GCTGCGCACCTGGGGCAGCAAGACCCCCGGGCACCCGGAGTACCGCCACACCGCGGGGGTCGAGACGACCACGGGCCCGC
TCGGTCAGGGCGTCGGCAACGCGGTCGGGATGGCGATGGCCGCGCGGCGGCTGCGTGGGCTGCTCGACCCGGGCGCGAAG
ACCGGGCCCTCGGTGTTCGACCACCGGGTCTACGCGATCTGCAGTGACGGAGACATCGAGGAGGGCGTGAGCGGCGAGGC
CTCCTCGATCGCCGGCACCCAGCAGCTCGGCAACCTCACGCTGATCTACGACGCCAACAAGATCTCCATCGAGGACGACA
CCAACATCGCCCTCAGCGAGGACGTGGCCGCGCGCTACGAGGCGTACGGCTGGCACGTCCAGGTCGTCGACTGGACCAAC
GGCGGCACCGAGTACCGCGAGGACGTGCACGCGCTGTACGACGCGCTCCGCGCCGCCGAGGCGGTCACCGACCGGCCCAG
CTTCATCGAGCTGAAGACGATCATCGCCTGGCCCGCGCCGAACGCGCAGGGCACCGGCAAGTCCCACGGATCCGCCCTCG
GGGCCGACGAGGTCGCCGCCACCAAGGAGGTCCTCGGCTTCGACCCGGCGCAGACCTTCGAGGTCCCGGAGGGCGTCCTC
GAGCACACCCGGCGACTCGGGGAGCGCGGTGCGGCCGCGGGCAAGGCCTGGGACGAGGACTTCGCCGCGTGGCGGGCCAA
GAACCCGGACGCCTTCGACGTGCTGATGCGGCTGCGCGGCCACGAGCTACCCGAGGGCTGGGCCGACGACCTGCCGGTCT
TCGACGCCGACCCGAAGGGGGTCGCGACGCGCAAGGCCTCCGGCCAGGTGATCAACGCGATCGCGAAGCGCGTCCCGGAG
CTCTGGGGCGGCTCCGCCGACCTCGCCGAGTCCAACAACACCACGATCGAGGACGTCCCGTCGTTCCTGCCGGTCGACCG
GTCCTCGAAGATGTGGGCGGGCGACCCGTACGCGGGCCGGGTGCTGCACTTCGGCATCCGTGAGCACGCGATGGGTTCGA
TCATGAACGGCATCGCCCTGCACAGTGGCACCCGCGTCTTCGGCGGCACCTTCCTCACGTTCTCCGACTACATGCGGCCC
GCGGTCCGGCTCGCGTCGCTGATGGGGCTCCCGGTCACCTACGTGTGGACCCACGACTCCATCGGTCTCGGCGAGGACGG
GCCGACGCACCAGCCGATCGAGCACCTCGCCGCGCTGCGCGCCATCCCCGGCCTCGACGTCATCCGGCCTGCGGACGCCA
ACGAGGTGGCCGCCTGCTGGAAGGCGGTCATGGAGCACACGGACCGGCCCTCCGCCCTGGCCCTCACCCGCCAGAACGTG
CCGGTGTTCCCGCGGGAGCAGGACGGCTTCGCCGGCACCGCCGACGTGCACCGGGGCGGCTACATCCTGATCGACGCCCC
CGAGATCGACGGCCAGGGCGGCCAGCCCGACGTCGTACTGATCGGCACCGGTTCGGAGGTCCAGCTGGCCGTCGAGGCCC
GAGCCCTGCTCGCCGAGGACGGGATCCGCGCCCGCGTGGTCTCGATGCCGTGCCGCGAGTGGTTCGCCGCCCAGCACGAG
TCCTACCGCGAGGCCGTCATCCCGCCGATCGTCAAGGCGCGCGTCTCGGTCGAGGCGGGCATCGCCCAGGGCTGGCACGA
GGTCGTCGGCGACCACGGCCGGATCGTCTCGATCGAGACGTACGGCGCCTCGGCCGACTACGCCCGCATCTACCAGGAGT
ACGGCATCACCGCCCGGGCCGTCGCCGACGCCGCCCGCGACAGCATCCGCGTGAGCAGCAGCTAG

Upstream 100 bases:

>100_bases
GAGGACCCTGCGGAACGATCCGCGCGCCCGCCTGCACCGGCCGTCGCTCGCGAGCGCCCGTCCCTGTCCGGCCGGGTCCC
CGGGGTGAGTAGGCTCGGGT

Downstream 100 bases:

>100_bases
TGCCGTAACCGGCTTCACCGCCTACGCGACCACCGACCACCTACATCGGAGGAACCCATGAGCGACCTACTGAAAGCCCT
CACCGACGCCGGTGTGTCCA

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MADDLERNPVTDTAALDWTDLDQKAVDTARVLAMDAVQKVGNGHPGTAMSLAPAAYLLFQKVMRHDPSDPRWIARDRFVL
SAGHSSLTLYIQLFLGGFGLELDDLKALRTWGSKTPGHPEYRHTAGVETTTGPLGQGVGNAVGMAMAARRLRGLLDPGAK
TGPSVFDHRVYAICSDGDIEEGVSGEASSIAGTQQLGNLTLIYDANKISIEDDTNIALSEDVAARYEAYGWHVQVVDWTN
GGTEYREDVHALYDALRAAEAVTDRPSFIELKTIIAWPAPNAQGTGKSHGSALGADEVAATKEVLGFDPAQTFEVPEGVL
EHTRRLGERGAAAGKAWDEDFAAWRAKNPDAFDVLMRLRGHELPEGWADDLPVFDADPKGVATRKASGQVINAIAKRVPE
LWGGSADLAESNNTTIEDVPSFLPVDRSSKMWAGDPYAGRVLHFGIREHAMGSIMNGIALHSGTRVFGGTFLTFSDYMRP
AVRLASLMGLPVTYVWTHDSIGLGEDGPTHQPIEHLAALRAIPGLDVIRPADANEVAACWKAVMEHTDRPSALALTRQNV
PVFPREQDGFAGTADVHRGGYILIDAPEIDGQGGQPDVVLIGTGSEVQLAVEARALLAEDGIRARVVSMPCREWFAAQHE
SYREAVIPPIVKARVSVEAGIAQGWHEVVGDHGRIVSIETYGASADYARIYQEYGITARAVADAARDSIRVSSS

Sequences:

>Translated_714_residues
MADDLERNPVTDTAALDWTDLDQKAVDTARVLAMDAVQKVGNGHPGTAMSLAPAAYLLFQKVMRHDPSDPRWIARDRFVL
SAGHSSLTLYIQLFLGGFGLELDDLKALRTWGSKTPGHPEYRHTAGVETTTGPLGQGVGNAVGMAMAARRLRGLLDPGAK
TGPSVFDHRVYAICSDGDIEEGVSGEASSIAGTQQLGNLTLIYDANKISIEDDTNIALSEDVAARYEAYGWHVQVVDWTN
GGTEYREDVHALYDALRAAEAVTDRPSFIELKTIIAWPAPNAQGTGKSHGSALGADEVAATKEVLGFDPAQTFEVPEGVL
EHTRRLGERGAAAGKAWDEDFAAWRAKNPDAFDVLMRLRGHELPEGWADDLPVFDADPKGVATRKASGQVINAIAKRVPE
LWGGSADLAESNNTTIEDVPSFLPVDRSSKMWAGDPYAGRVLHFGIREHAMGSIMNGIALHSGTRVFGGTFLTFSDYMRP
AVRLASLMGLPVTYVWTHDSIGLGEDGPTHQPIEHLAALRAIPGLDVIRPADANEVAACWKAVMEHTDRPSALALTRQNV
PVFPREQDGFAGTADVHRGGYILIDAPEIDGQGGQPDVVLIGTGSEVQLAVEARALLAEDGIRARVVSMPCREWFAAQHE
SYREAVIPPIVKARVSVEAGIAQGWHEVVGDHGRIVSIETYGASADYARIYQEYGITARAVADAARDSIRVSSS
>Mature_713_residues
ADDLERNPVTDTAALDWTDLDQKAVDTARVLAMDAVQKVGNGHPGTAMSLAPAAYLLFQKVMRHDPSDPRWIARDRFVLS
AGHSSLTLYIQLFLGGFGLELDDLKALRTWGSKTPGHPEYRHTAGVETTTGPLGQGVGNAVGMAMAARRLRGLLDPGAKT
GPSVFDHRVYAICSDGDIEEGVSGEASSIAGTQQLGNLTLIYDANKISIEDDTNIALSEDVAARYEAYGWHVQVVDWTNG
GTEYREDVHALYDALRAAEAVTDRPSFIELKTIIAWPAPNAQGTGKSHGSALGADEVAATKEVLGFDPAQTFEVPEGVLE
HTRRLGERGAAAGKAWDEDFAAWRAKNPDAFDVLMRLRGHELPEGWADDLPVFDADPKGVATRKASGQVINAIAKRVPEL
WGGSADLAESNNTTIEDVPSFLPVDRSSKMWAGDPYAGRVLHFGIREHAMGSIMNGIALHSGTRVFGGTFLTFSDYMRPA
VRLASLMGLPVTYVWTHDSIGLGEDGPTHQPIEHLAALRAIPGLDVIRPADANEVAACWKAVMEHTDRPSALALTRQNVP
VFPREQDGFAGTADVHRGGYILIDAPEIDGQGGQPDVVLIGTGSEVQLAVEARALLAEDGIRARVVSMPCREWFAAQHES
YREAVIPPIVKARVSVEAGIAQGWHEVVGDHGRIVSIETYGASADYARIYQEYGITARAVADAARDSIRVSSS

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=619, Percent_Identity=26.4943457189015, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI4507521, Length=619, Percent_Identity=26.4943457189015, Blast_Score=149, Evalue=1e-35,
Organism=Homo sapiens, GI133778974, Length=615, Percent_Identity=24.390243902439, Blast_Score=114, Evalue=3e-25,
Organism=Escherichia coli, GI48994911, Length=695, Percent_Identity=43.0215827338129, Blast_Score=523, Evalue=1e-149,
Organism=Escherichia coli, GI1788808, Length=692, Percent_Identity=42.0520231213873, Blast_Score=511, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI17539652, Length=614, Percent_Identity=25.4071661237785, Blast_Score=138, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6325331, Length=697, Percent_Identity=43.1850789096126, Blast_Score=526, Evalue=1e-150,
Organism=Saccharomyces cerevisiae, GI6319593, Length=699, Percent_Identity=42.346208869814, Blast_Score=510, Evalue=1e-145,
Organism=Drosophila melanogaster, GI45551847, Length=622, Percent_Identity=26.5273311897106, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI45550715, Length=622, Percent_Identity=26.5273311897106, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24645119, Length=582, Percent_Identity=26.1168384879725, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24666278, Length=621, Percent_Identity=26.0869565217391, Blast_Score=133, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 76840; Mature: 76709

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADDLERNPVTDTAALDWTDLDQKAVDTARVLAMDAVQKVGNGHPGTAMSLAPAAYLLFQ
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KVMRHDPSDPRWIARDRFVLSAGHSSLTLYIQLFLGGFGLELDDLKALRTWGSKTPGHPE
HHHHCCCCCCCEEECCCEEEECCCCHHEEHHEEHHCCCCCCHHHHHHHHHCCCCCCCCCC
YRHTAGVETTTGPLGQGVGNAVGMAMAARRLRGLLDPGAKTGPSVFDHRVYAICSDGDIE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEEEECCCCCC
EGVSGEASSIAGTQQLGNLTLIYDANKISIEDDTNIALSEDVAARYEAYGWHVQVVDWTN
CCCCCCHHHCCCHHHHCCEEEEEECCEEEECCCCCEEECHHHHHHHHHCCEEEEEEEECC
GGTEYREDVHALYDALRAAEAVTDRPSFIELKTIIAWPAPNAQGTGKSHGSALGADEVAA
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHH
TKEVLGFDPAQTFEVPEGVLEHTRRLGERGAAAGKAWDEDFAAWRAKNPDAFDVLMRLRG
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHC
HELPEGWADDLPVFDADPKGVATRKASGQVINAIAKRVPELWGGSADLAESNNTTIEDVP
CCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
SFLPVDRSSKMWAGDPYAGRVLHFGIREHAMGSIMNGIALHSGTRVFGGTFLTFSDYMRP
HHCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCEEECCEEEEHHHHHHH
AVRLASLMGLPVTYVWTHDSIGLGEDGPTHQPIEHLAALRAIPGLDVIRPADANEVAACW
HHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
KAVMEHTDRPSALALTRQNVPVFPREQDGFAGTADVHRGGYILIDAPEIDGQGGQPDVVL
HHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEECCCCEEEEECCCCCCCCCCCCEEE
IGTGSEVQLAVEARALLAEDGIRARVVSMPCREWFAAQHESYREAVIPPIVKARVSVEAG
EECCCCEEEEHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IAQGWHEVVGDHGRIVSIETYGASADYARIYQEYGITARAVADAARDSIRVSSS
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCEEECCC
>Mature Secondary Structure 
ADDLERNPVTDTAALDWTDLDQKAVDTARVLAMDAVQKVGNGHPGTAMSLAPAAYLLFQ
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
KVMRHDPSDPRWIARDRFVLSAGHSSLTLYIQLFLGGFGLELDDLKALRTWGSKTPGHPE
HHHHCCCCCCCEEECCCEEEECCCCHHEEHHEEHHCCCCCCHHHHHHHHHCCCCCCCCCC
YRHTAGVETTTGPLGQGVGNAVGMAMAARRLRGLLDPGAKTGPSVFDHRVYAICSDGDIE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEEEECCCCCC
EGVSGEASSIAGTQQLGNLTLIYDANKISIEDDTNIALSEDVAARYEAYGWHVQVVDWTN
CCCCCCHHHCCCHHHHCCEEEEEECCEEEECCCCCEEECHHHHHHHHHCCEEEEEEEECC
GGTEYREDVHALYDALRAAEAVTDRPSFIELKTIIAWPAPNAQGTGKSHGSALGADEVAA
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHH
TKEVLGFDPAQTFEVPEGVLEHTRRLGERGAAAGKAWDEDFAAWRAKNPDAFDVLMRLRG
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHC
HELPEGWADDLPVFDADPKGVATRKASGQVINAIAKRVPELWGGSADLAESNNTTIEDVP
CCCCCCCCCCCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
SFLPVDRSSKMWAGDPYAGRVLHFGIREHAMGSIMNGIALHSGTRVFGGTFLTFSDYMRP
HHCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCEEECCEEEEHHHHHHH
AVRLASLMGLPVTYVWTHDSIGLGEDGPTHQPIEHLAALRAIPGLDVIRPADANEVAACW
HHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
KAVMEHTDRPSALALTRQNVPVFPREQDGFAGTADVHRGGYILIDAPEIDGQGGQPDVVL
HHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCEECCCCEEEEECCCCCCCCCCCCEEE
IGTGSEVQLAVEARALLAEDGIRARVVSMPCREWFAAQHESYREAVIPPIVKARVSVEAG
EECCCCEEEEHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
IAQGWHEVVGDHGRIVSIETYGASADYARIYQEYGITARAVADAARDSIRVSSS
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]