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The map label for this gene is bcd [H]

Identifier: 119716742

GI number: 119716742

Start: 2683044

End: 2684156

Strand: Reverse

Name: bcd [H]

Synonym: Noca_2516

Alternate gene names: 119716742

Gene position: 2684156-2683044 (Counterclockwise)

Preceding gene: 119716743

Following gene: 119716741

Centisome position: 53.84

GC content: 76.28

Gene sequence:

>1113_bases
ATGGACTTCACCTTCACCCCCGAGCAGGACGAGGCCGCCGCGCTCGCGGCCGGCATCCTGCGCGACCGCGCGACCACCGA
GCGGCTGAAGGCCGTCGAGGCCGGCGGCGACCGCTTCGACCGCGACCTGTGGGCCGAGCTCGGCGCGGCGGGGCTGCTCG
GCCTCGCGCTGCCGGAGCGGTACGACGGCGCCGGGCTCGGCCTGATCGAGCTGTGCCGCGTGCTCGTCGAGGTCGGCCGC
ACCGTGGCGCCGGTGCCACTAGTGGCGCACGGGCCCGCCGCGCGGCTGCTCGCCGAGTCCGGACCCACTGCGCTCCAGGA
GCGGTGGCTGCCCGGTGCCGTGGCGGGTGCGCTCGTGCTGACCGCGGCGGTCGCCGAGGAGCGGGCGTTCGCACCGAGCC
GGCCGACGACCGTGGCCACGCCCGACGGCGAGGGCTACCGGATCACCGGGAGCAAGGCGATCGTGCCGGCCGGGCCGTAC
GCCGACGCGTTCCTGGTGCCCGCCGAGACGCCGTCCGGCACCGGCGTCTTCCTGGTCGAGCCGGGCGACCCCGGGCTGAC
CGTGGTCGCCCAGACGTTCTCCGACCGGGACGGCGTGGCCCGCCTCGACCTGGACGGCGTCGCCGTCGGGTCGGACCGCG
CGGTCGGCGCCGCCGACGGGTCGACCGACCGCCGGCTGCGCCACCTGCTGCTGCTCGCGGCGAGCGCCGAGCAGCTCGGC
ATCACCGAGGGGTCGCTCCGGCTCACCTCGTCGTACGCGAAGACGCGCGAGCAGTTCGGCCGGCCGATCGGGACCTTCCA
GGCGGTCTCGCAGCGGCTGGCGGACGGCTACATCGACGTGCTCGGCCAGCGCCTGACGCTGTGGCAGGCGGCCTGGCGCC
TCGAGGAGGGATTGCCGGCCGACAGCGAGGTCGCGATCGCGAAGCTGTGGGCGGCCGACGCCGGGCACCGGCTCGCGCAC
ACCACCGTGCACGTGCACGGCGGCGTCGGCATCGACCTGGACGGCGAGGCGCACCGCTACTTCACGAGCGCCAAGCGCTT
CGAGTTCCTCCACGGCGGGGCGACCGAGCAGGCGCTGGCCGTCGGACGAGCCCTGGCCGCCGAACCCGCCTGA

Upstream 100 bases:

>100_bases
GATGACCTTCGGCGGCGGCACCAACGAGATCCAGCGCGACATCATCGGCTACGTCGGGCTCGGACTGCCCGCGACGAAGA
GGTAGGACAGAGGGACGACC

Downstream 100 bases:

>100_bases
TCGCCGACTCGGGCTCTCCTGCTGAATGTGTGGGTGGGTTGAGCGTGCCGTAGACGGGCGCACGCCGCTCTCTGCCTAGG
TTTTGGAGCTGTCTAGGAAC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MDFTFTPEQDEAAALAAGILRDRATTERLKAVEAGGDRFDRDLWAELGAAGLLGLALPERYDGAGLGLIELCRVLVEVGR
TVAPVPLVAHGPAARLLAESGPTALQERWLPGAVAGALVLTAAVAEERAFAPSRPTTVATPDGEGYRITGSKAIVPAGPY
ADAFLVPAETPSGTGVFLVEPGDPGLTVVAQTFSDRDGVARLDLDGVAVGSDRAVGAADGSTDRRLRHLLLLAASAEQLG
ITEGSLRLTSSYAKTREQFGRPIGTFQAVSQRLADGYIDVLGQRLTLWQAAWRLEEGLPADSEVAIAKLWAADAGHRLAH
TTVHVHGGVGIDLDGEAHRYFTSAKRFEFLHGGATEQALAVGRALAAEPA

Sequences:

>Translated_370_residues
MDFTFTPEQDEAAALAAGILRDRATTERLKAVEAGGDRFDRDLWAELGAAGLLGLALPERYDGAGLGLIELCRVLVEVGR
TVAPVPLVAHGPAARLLAESGPTALQERWLPGAVAGALVLTAAVAEERAFAPSRPTTVATPDGEGYRITGSKAIVPAGPY
ADAFLVPAETPSGTGVFLVEPGDPGLTVVAQTFSDRDGVARLDLDGVAVGSDRAVGAADGSTDRRLRHLLLLAASAEQLG
ITEGSLRLTSSYAKTREQFGRPIGTFQAVSQRLADGYIDVLGQRLTLWQAAWRLEEGLPADSEVAIAKLWAADAGHRLAH
TTVHVHGGVGIDLDGEAHRYFTSAKRFEFLHGGATEQALAVGRALAAEPA
>Mature_370_residues
MDFTFTPEQDEAAALAAGILRDRATTERLKAVEAGGDRFDRDLWAELGAAGLLGLALPERYDGAGLGLIELCRVLVEVGR
TVAPVPLVAHGPAARLLAESGPTALQERWLPGAVAGALVLTAAVAEERAFAPSRPTTVATPDGEGYRITGSKAIVPAGPY
ADAFLVPAETPSGTGVFLVEPGDPGLTVVAQTFSDRDGVARLDLDGVAVGSDRAVGAADGSTDRRLRHLLLLAASAEQLG
ITEGSLRLTSSYAKTREQFGRPIGTFQAVSQRLADGYIDVLGQRLTLWQAAWRLEEGLPADSEVAIAKLWAADAGHRLAH
TTVHVHGGVGIDLDGEAHRYFTSAKRFEFLHGGATEQALAVGRALAAEPA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=352, Percent_Identity=28.125, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI226958414, Length=352, Percent_Identity=27.8409090909091, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI4557233, Length=332, Percent_Identity=25, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4501859, Length=358, Percent_Identity=23.7430167597765, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI187960098, Length=391, Percent_Identity=25.3196930946292, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI4557231, Length=391, Percent_Identity=25.3196930946292, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI76496475, Length=358, Percent_Identity=25.4189944134078, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4557235, Length=358, Percent_Identity=25.4189944134078, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786223, Length=386, Percent_Identity=25.6476683937824, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=23.3595800524934, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538396, Length=357, Percent_Identity=26.0504201680672, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71990804, Length=293, Percent_Identity=28.3276450511945, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17508101, Length=336, Percent_Identity=25.297619047619, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17506239, Length=336, Percent_Identity=25, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=386, Percent_Identity=24.8704663212435, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=23.6220472440945, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17570075, Length=397, Percent_Identity=25.4408060453401, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=245, Percent_Identity=26.9387755102041, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356377, Length=377, Percent_Identity=25.1989389920424, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24646207, Length=335, Percent_Identity=27.1641791044776, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24666513, Length=352, Percent_Identity=25.5681818181818, Blast_Score=98, Evalue=9e-21,
Organism=Drosophila melanogaster, GI21355753, Length=356, Percent_Identity=26.123595505618, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24660351, Length=388, Percent_Identity=27.0618556701031, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 38705; Mature: 38705

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTFTPEQDEAAALAAGILRDRATTERLKAVEAGGDRFDRDLWAELGAAGLLGLALPER
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHCCCCC
YDGAGLGLIELCRVLVEVGRTVAPVPLVAHGPAARLLAESGPTALQERWLPGAVAGALVL
CCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHCCCCHHHHHCCCCHHHHHHHHH
TAAVAEERAFAPSRPTTVATPDGEGYRITGSKAIVPAGPYADAFLVPAETPSGTGVFLVE
HHHHHHHHCCCCCCCCEEECCCCCCEEEECCCEEECCCCCCCEEEEECCCCCCCEEEEEE
PGDPGLTVVAQTFSDRDGVARLDLDGVAVGSDRAVGAADGSTDRRLRHLLLLAASAEQLG
CCCCCEEEEEEECCCCCCEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCHHHHC
ITEGSLRLTSSYAKTREQFGRPIGTFQAVSQRLADGYIDVLGQRLTLWQAAWRLEEGLPA
CCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DSEVAIAKLWAADAGHRLAHTTVHVHGGVGIDLDGEAHRYFTSAKRFEFLHGGATEQALA
CCCHHHHHHHHCCCCCEEEEEEEEEECCEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHH
VGRALAAEPA
HHHHHHCCCC
>Mature Secondary Structure
MDFTFTPEQDEAAALAAGILRDRATTERLKAVEAGGDRFDRDLWAELGAAGLLGLALPER
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHCCCCC
YDGAGLGLIELCRVLVEVGRTVAPVPLVAHGPAARLLAESGPTALQERWLPGAVAGALVL
CCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCHHHHHHCCCCHHHHHCCCCHHHHHHHHH
TAAVAEERAFAPSRPTTVATPDGEGYRITGSKAIVPAGPYADAFLVPAETPSGTGVFLVE
HHHHHHHHCCCCCCCCEEECCCCCCEEEECCCEEECCCCCCCEEEEECCCCCCCEEEEEE
PGDPGLTVVAQTFSDRDGVARLDLDGVAVGSDRAVGAADGSTDRRLRHLLLLAASAEQLG
CCCCCEEEEEEECCCCCCEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCHHHHC
ITEGSLRLTSSYAKTREQFGRPIGTFQAVSQRLADGYIDVLGQRLTLWQAAWRLEEGLPA
CCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DSEVAIAKLWAADAGHRLAHTTVHVHGGVGIDLDGEAHRYFTSAKRFEFLHGGATEQALA
CCCHHHHHHHHCCCCCEEEEEEEEEECCEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHH
VGRALAAEPA
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]