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The map label for this gene is yxlA [H]

Identifier: 119715352

GI number: 119715352

Start: 1177372

End: 1178850

Strand: Direct

Name: yxlA [H]

Synonym: Noca_1114

Alternate gene names: 119715352

Gene position: 1177372-1178850 (Clockwise)

Preceding gene: 119715351

Following gene: 119715353

Centisome position: 23.61

GC content: 65.86

Gene sequence:

>1479_bases
ATGGCAAGGTATGACGTGGCACCTTCGGAGGCGCCGACTGGTGGTGGCTCGCTGCGCTGGAACAAGGTCGAGTCCCGCTC
GATCGACTACGTGCCGCTCTCCGAACGGCACGGTCGGCTGACTGATCAGTTCACGATCTGGTTCGCGGGCAGCGCGATGT
TGTTGAGCCTCGCCACCGGCGTCATCGGCATCGGTCTGGGTCTCAACCTGATCTGGACGCTGATCGCGTTGGCGGTGGGG
ACGTTCCTGGGAACTCTTCCTGTGGCCGCGCACGCCAGTCAGGGCCCTCACCTGGGGCTTCCGCAGATGATCCAGAGTCG
TCCCCAGTTCGGACGCTATGGCGCTCTGTTCATCTGGGTCGTCGCGTTCGCCGTCTACTGGGGCTACGTCGTGCTGGACG
TGAACCTCTTCGGGCCCACGGCAACCCAGGTCGTGGGTGGCTCCAGGCCGGTCTGGGCGATCGTGATCGGCCTGATCTCC
ATGGTGATCACGATCTTCGGCTACCACTGGATGCACGCCGGGCAGCGCTGGGTCACGGTGGTCCTCGTCGTCGTGCTGGC
GGTCTACGCGGTCGGCATCCTCACGGGAGGCGAGCTGCCCGCGGGTGCTCTCAGCCTGTCGACCGGGTTCCAGTTCGCAC
CGTTCTTCATGGTGATGTCGGCCGCCTTGGCCTACCAGCTCTCGTGGGCGTTCTTCGTCTCGGACTACTCCCGCTACATG
CCGCCGACCACCAGCCACCGGGCGATCATCTTCTTCACGGCATCGGGTGCCGGCCTGGGCGTCTTCTCGATGGAGGCGGT
CGGAGCCGTCGGTGCTGCCCTGTTCCCGTCCGAATCGGTCACCGTCGCGCTGGCGGAGTCGGGCGACACGGTCTTCAACG
GGCTGGGCACCATCGTCCTCCTCGTCGGCGGTCTGGCGCTGGTCGTCTTCAACGCCATGTGCATCTACGGCGGAGCGTTG
ACCGCGATCACCGCGCTGGACAGTTTGCGGCCGGTGGCACCGACCCACCGGGTCCGCACGGGCGCGATCGTCGCCGTGGG
GGTGACGGCCACGCTCGTGGGGGCCTTCCTGCCAGACGACTTCATCGGCACGACCTTCTACACGATCCTCGCCGTGCTGG
CCTACCTGATGGGTCCGTGGACCGCGATCAACCTCACCGACTACTTCCTGGTGCGGCGCGGCCGCTACTCCATCACCGAG
ATCTTCAACCCGAACGGGATGTACGGGCGCTGGCACGCTGCAGGCATCGTCGCCTACGTCCTCGGGTTCGTGGTCATGGT
GCCGTTCATGTACCTGTCCTTCTACGAGGGCTTCGCGGCGAAGTGGCTCAACGACGTGGACATCGCCTTCTTCGTCGGTA
TCCCCGTTGCCGCGATCGTCTACTACGCGCTCTCCCGCAACCTCGACCTCGACAACGAGCGCGCCGTCATCCGGCAGGCA
GACGCGCACCTCGAGGAGCTCGGCGAGCCCATCGAGTAG

Upstream 100 bases:

>100_bases
CGCCGCTCAGCCGTGACAGGGCCCCCAGGGGCCGGAGCACTAGGGAATCGTCTACGCCCGACCGTGAACCTTCACACGGT
CGTCTGGAATGAGGAGTCTG

Downstream 100 bases:

>100_bases
TGCCGCCGCCCGGCGTGGCCGCCAATGGCCGACACCGCGCCGTACCACCGACGACAGCACCCGAAAGCAGGAACAGCACC
ATGGACCAAACGACGGAGTT

Product: cytosine/purines, uracil, thiamine, allantoin permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MARYDVAPSEAPTGGGSLRWNKVESRSIDYVPLSERHGRLTDQFTIWFAGSAMLLSLATGVIGIGLGLNLIWTLIALAVG
TFLGTLPVAAHASQGPHLGLPQMIQSRPQFGRYGALFIWVVAFAVYWGYVVLDVNLFGPTATQVVGGSRPVWAIVIGLIS
MVITIFGYHWMHAGQRWVTVVLVVVLAVYAVGILTGGELPAGALSLSTGFQFAPFFMVMSAALAYQLSWAFFVSDYSRYM
PPTTSHRAIIFFTASGAGLGVFSMEAVGAVGAALFPSESVTVALAESGDTVFNGLGTIVLLVGGLALVVFNAMCIYGGAL
TAITALDSLRPVAPTHRVRTGAIVAVGVTATLVGAFLPDDFIGTTFYTILAVLAYLMGPWTAINLTDYFLVRRGRYSITE
IFNPNGMYGRWHAAGIVAYVLGFVVMVPFMYLSFYEGFAAKWLNDVDIAFFVGIPVAAIVYYALSRNLDLDNERAVIRQA
DAHLEELGEPIE

Sequences:

>Translated_492_residues
MARYDVAPSEAPTGGGSLRWNKVESRSIDYVPLSERHGRLTDQFTIWFAGSAMLLSLATGVIGIGLGLNLIWTLIALAVG
TFLGTLPVAAHASQGPHLGLPQMIQSRPQFGRYGALFIWVVAFAVYWGYVVLDVNLFGPTATQVVGGSRPVWAIVIGLIS
MVITIFGYHWMHAGQRWVTVVLVVVLAVYAVGILTGGELPAGALSLSTGFQFAPFFMVMSAALAYQLSWAFFVSDYSRYM
PPTTSHRAIIFFTASGAGLGVFSMEAVGAVGAALFPSESVTVALAESGDTVFNGLGTIVLLVGGLALVVFNAMCIYGGAL
TAITALDSLRPVAPTHRVRTGAIVAVGVTATLVGAFLPDDFIGTTFYTILAVLAYLMGPWTAINLTDYFLVRRGRYSITE
IFNPNGMYGRWHAAGIVAYVLGFVVMVPFMYLSFYEGFAAKWLNDVDIAFFVGIPVAAIVYYALSRNLDLDNERAVIRQA
DAHLEELGEPIE
>Mature_491_residues
ARYDVAPSEAPTGGGSLRWNKVESRSIDYVPLSERHGRLTDQFTIWFAGSAMLLSLATGVIGIGLGLNLIWTLIALAVGT
FLGTLPVAAHASQGPHLGLPQMIQSRPQFGRYGALFIWVVAFAVYWGYVVLDVNLFGPTATQVVGGSRPVWAIVIGLISM
VITIFGYHWMHAGQRWVTVVLVVVLAVYAVGILTGGELPAGALSLSTGFQFAPFFMVMSAALAYQLSWAFFVSDYSRYMP
PTTSHRAIIFFTASGAGLGVFSMEAVGAVGAALFPSESVTVALAESGDTVFNGLGTIVLLVGGLALVVFNAMCIYGGALT
AITALDSLRPVAPTHRVRTGAIVAVGVTATLVGAFLPDDFIGTTFYTILAVLAYLMGPWTAINLTDYFLVRRGRYSITEI
FNPNGMYGRWHAAGIVAYVLGFVVMVPFMYLSFYEGFAAKWLNDVDIAFFVGIPVAAIVYYALSRNLDLDNERAVIRQAD
AHLEELGEPIE

Specific function: Unknown

COG id: COG1457

COG function: function code F; Purine-cytosine permease and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine-cytosine permease family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320903, Length=396, Percent_Identity=26.2626262626263, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6320897, Length=483, Percent_Identity=24.223602484472, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320902, Length=485, Percent_Identity=21.8556701030928, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001248 [H]

Pfam domain/function: PF02133 Transp_cyt_pur [H]

EC number: NA

Molecular weight: Translated: 52834; Mature: 52703

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARYDVAPSEAPTGGGSLRWNKVESRSIDYVPLSERHGRLTDQFTIWFAGSAMLLSLATG
CCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHH
VIGIGLGLNLIWTLIALAVGTFLGTLPVAAHASQGPHLGLPQMIQSRPQFGRYGALFIWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHH
VAFAVYWGYVVLDVNLFGPTATQVVGGSRPVWAIVIGLISMVITIFGYHWMHAGQRWVTV
HHHHHHHCEEEEEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VLVVVLAVYAVGILTGGELPAGALSLSTGFQFAPFFMVMSAALAYQLSWAFFVSDYSRYM
HHHHHHHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PPTTSHRAIIFFTASGAGLGVFSMEAVGAVGAALFPSESVTVALAESGDTVFNGLGTIVL
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
LVGGLALVVFNAMCIYGGALTAITALDSLRPVAPTHRVRTGAIVAVGVTATLVGAFLPDD
HHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCH
FIGTTFYTILAVLAYLMGPWTAINLTDYFLVRRGRYSITEIFNPNGMYGRWHAAGIVAYV
HHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHH
LGFVVMVPFMYLSFYEGFAAKWLNDVDIAFFVGIPVAAIVYYALSRNLDLDNERAVIRQA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
DAHLEELGEPIE
HHHHHHCCCCCC
>Mature Secondary Structure 
ARYDVAPSEAPTGGGSLRWNKVESRSIDYVPLSERHGRLTDQFTIWFAGSAMLLSLATG
CCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHH
VIGIGLGLNLIWTLIALAVGTFLGTLPVAAHASQGPHLGLPQMIQSRPQFGRYGALFIWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCHHHHHHHH
VAFAVYWGYVVLDVNLFGPTATQVVGGSRPVWAIVIGLISMVITIFGYHWMHAGQRWVTV
HHHHHHHCEEEEEEEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
VLVVVLAVYAVGILTGGELPAGALSLSTGFQFAPFFMVMSAALAYQLSWAFFVSDYSRYM
HHHHHHHHHHHHHHCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PPTTSHRAIIFFTASGAGLGVFSMEAVGAVGAALFPSESVTVALAESGDTVFNGLGTIVL
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
LVGGLALVVFNAMCIYGGALTAITALDSLRPVAPTHRVRTGAIVAVGVTATLVGAFLPDD
HHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCH
FIGTTFYTILAVLAYLMGPWTAINLTDYFLVRRGRYSITEIFNPNGMYGRWHAAGIVAYV
HHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHH
LGFVVMVPFMYLSFYEGFAAKWLNDVDIAFFVGIPVAAIVYYALSRNLDLDNERAVIRQA
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
DAHLEELGEPIE
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]