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The map label for this gene is uppS1 [H]

Identifier: 119715296

GI number: 119715296

Start: 1114149

End: 1114925

Strand: Direct

Name: uppS1 [H]

Synonym: Noca_1056

Alternate gene names: 119715296

Gene position: 1114149-1114925 (Clockwise)

Preceding gene: 119715293

Following gene: 119715297

Centisome position: 22.35

GC content: 72.07

Gene sequence:

>777_bases
GTGGCGGACTGGAAGCGCGGGCTCCGGCGGGTGCTCTACCCGGCCTACGAGGCACGGATGCTGCGCCGGATGCCGTCGGA
GAACCTGCCCAAGCACATCGGGGTGATGCTCGACGGCAACCGTCGCTGGGCCCGGGCTGTGGGCCGTGACACCGCCGACG
GGCACCAAGCGGGCGCGGCCAACATCGAGCCGCTGCTGGGGTGGTGCGACGAGGTCGGCACCGAGGTCGTCACCCTGTGG
CTGCTCTCCACCGACAACCTCAACCGCCCCGAGCGCGAGCTCGCTCCGCTGCTCGAGATCATCGCCGACGCGGTGGACTC
GCTCGCCGACCAGCGACGCTGGCGGGTGCACCCCGTCGGTGCCCTCGACCTGCTGCCCGCGTCGGTGGCCGAGCGGCTCA
AGGCCGCCGAGGAGGCCACCCGCGACGTCGACGGGATGCTGGTCAACGTGGCGGTCGGGTACGGCGGCCGGCGCGAGATC
GCGGACGCCGTACGCTCCCTGCTCCAGGAGGCCGCCGTCAACGGCACCTCGCTCGAGGAGCTCGCTTCGGCCATCGACGT
CGAGTCGATCGCCGAGCACCTCTACACCAAGGGCCAGCCCGACCCCGACCTGGTGATCCGCACCTCGGGGGAGCAGCGGC
TCGGCGGCTTCCTGCTCTGGCAGAGCGCGAAGTCGGAGTTCTACTTCTGCGAGGCCTACTGGCCCGACTTCCGCCGCGTC
GACTTCCTGCGCGCCCTGCGCGCCTACACCCTGCGCGAGCGTCGGTACGGCGCCTGA

Upstream 100 bases:

>100_bases
CGGCAACCCCGGATCCGGCCGGTCCGGGCGAGCGAGGCGGTGGACGTCACGTCGTCGAGAGCGCCACGAGGCGGCCTCGA
CCGCCGGTACCATCGCAGTC

Downstream 100 bases:

>100_bases
GAGTTTCATCGGCCGGCCGATGAAACTCGACCCTGGACGATGAAACTTCATCGTCCAGGCACGAGTTCTGTCGGCCGGCC
GACGAAAGTGGGCGGCTCCT

Product: undecaprenyl pyrophosphate synthetase

Products: NA

Alternate protein names: UPP synthase 1; Di-trans,poly-cis-decaprenylcistransferase 1; Undecaprenyl diphosphate synthase 1; UDS 1 [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MADWKRGLRRVLYPAYEARMLRRMPSENLPKHIGVMLDGNRRWARAVGRDTADGHQAGAANIEPLLGWCDEVGTEVVTLW
LLSTDNLNRPERELAPLLEIIADAVDSLADQRRWRVHPVGALDLLPASVAERLKAAEEATRDVDGMLVNVAVGYGGRREI
ADAVRSLLQEAAVNGTSLEELASAIDVESIAEHLYTKGQPDPDLVIRTSGEQRLGGFLLWQSAKSEFYFCEAYWPDFRRV
DFLRALRAYTLRERRYGA

Sequences:

>Translated_258_residues
MADWKRGLRRVLYPAYEARMLRRMPSENLPKHIGVMLDGNRRWARAVGRDTADGHQAGAANIEPLLGWCDEVGTEVVTLW
LLSTDNLNRPERELAPLLEIIADAVDSLADQRRWRVHPVGALDLLPASVAERLKAAEEATRDVDGMLVNVAVGYGGRREI
ADAVRSLLQEAAVNGTSLEELASAIDVESIAEHLYTKGQPDPDLVIRTSGEQRLGGFLLWQSAKSEFYFCEAYWPDFRRV
DFLRALRAYTLRERRYGA
>Mature_257_residues
ADWKRGLRRVLYPAYEARMLRRMPSENLPKHIGVMLDGNRRWARAVGRDTADGHQAGAANIEPLLGWCDEVGTEVVTLWL
LSTDNLNRPERELAPLLEIIADAVDSLADQRRWRVHPVGALDLLPASVAERLKAAEEATRDVDGMLVNVAVGYGGRREIA
DAVRSLLQEAAVNGTSLEELASAIDVESIAEHLYTKGQPDPDLVIRTSGEQRLGGFLLWQSAKSEFYFCEAYWPDFRRVD
FLRALRAYTLRERRYGA

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI45580742, Length=249, Percent_Identity=30.1204819277108, Blast_Score=130, Evalue=9e-31,
Organism=Homo sapiens, GI45580738, Length=249, Percent_Identity=30.1204819277108, Blast_Score=130, Evalue=9e-31,
Organism=Escherichia coli, GI1786371, Length=240, Percent_Identity=35.8333333333333, Blast_Score=155, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71993029, Length=246, Percent_Identity=28.4552845528455, Blast_Score=123, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319474, Length=228, Percent_Identity=32.4561403508772, Blast_Score=121, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6323748, Length=219, Percent_Identity=26.4840182648402, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI18857969, Length=228, Percent_Identity=33.3333333333333, Blast_Score=135, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 28999; Mature: 28868

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00422 GRANINS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADWKRGLRRVLYPAYEARMLRRMPSENLPKHIGVMLDGNRRWARAVGRDTADGHQAGAA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCEEECCCHHHHHHHCCCCCCCCCCCCC
NIEPLLGWCDEVGTEVVTLWLLSTDNLNRPERELAPLLEIIADAVDSLADQRRWRVHPVG
CHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ALDLLPASVAERLKAAEEATRDVDGMLVNVAVGYGGRREIADAVRSLLQEAAVNGTSLEE
HHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHH
LASAIDVESIAEHLYTKGQPDPDLVIRTSGEQRLGGFLLWQSAKSEFYFCEAYWPDFRRV
HHHHHCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHEEECCCCCEEEEEECCCCHHHH
DFLRALRAYTLRERRYGA
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ADWKRGLRRVLYPAYEARMLRRMPSENLPKHIGVMLDGNRRWARAVGRDTADGHQAGAA
CHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCEEECCCHHHHHHHCCCCCCCCCCCCC
NIEPLLGWCDEVGTEVVTLWLLSTDNLNRPERELAPLLEIIADAVDSLADQRRWRVHPVG
CHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ALDLLPASVAERLKAAEEATRDVDGMLVNVAVGYGGRREIADAVRSLLQEAAVNGTSLEE
HHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCHHH
LASAIDVESIAEHLYTKGQPDPDLVIRTSGEQRLGGFLLWQSAKSEFYFCEAYWPDFRRV
HHHHHCHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHEEECCCCCEEEEEECCCCHHHH
DFLRALRAYTLRERRYGA
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]