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The map label for this gene is menB [C]

Identifier: 119715107

GI number: 119715107

Start: 900219

End: 900980

Strand: Direct

Name: menB [C]

Synonym: Noca_0862

Alternate gene names: 119715107

Gene position: 900219-900980 (Clockwise)

Preceding gene: 119715106

Following gene: 119715108

Centisome position: 18.06

GC content: 72.83

Gene sequence:

>762_bases
GTGAGTGGCCTGCTCCGGGTCGGGACCCGGCAGGGCTTCGACACCCTGGAGATCGACTCGCCCACGAACCGCAACGCTCT
CTCGGTCGAGCTGCTCACCGCGCTGCACGACGAGGTGCGTCGCTCGGCGACCGGCACGGGCCGCGGACTCCTGGTCCAGC
ACGTCGGGCCGGCGTTCTGCTCCGGCGTGGACCTCAAGGAGCGCGCGGCACTCGGCCCTGACGACAGCTCCCACTCCGAG
CTCCTCGCCCACCTGCTCCGCGAGCTCTGGCACTACCCCAAGCCCGTCGTGGTCATGGTCGACGGTGCCGTGCGTGGTGG
CGGCTTGGGACTGCTGGCCTGCGCCGACGTCGTCCTGGCGACGGCCCGCTCGAGCTTCGCCTACTCCGAGTCGCGGGTCG
GCGTCGCGCCGGCGCTGGTGATGGCCGTGACGCTGCCGCTCGCCGACGTCCGCGCGCTGGTGCCGCGGCTGCTCGACGGC
GCGGTGTTCGGGGCGGTGACCGCGCACGAGCTCGGCCTGGTCACCAGGGTCGTCGAGGACGCGTCGAAGGTCTCGACGGT
CCTCTCCGAGCTCCGCCAGGGCGCCCCCGATGCACAGCGCGTGATCAAGACACTGGCCCGACAACGGATCGGAGTGGACG
TGGACGGTCTCCTGGTGGAGATGGCCGGCGTGTCGGCCCGGCTCTTCGCCGGCGCGGAGGCGGCCGAAGGCGTCGCCGCG
TTCACCTCCAGGCGCAGCCCGTCGTGGGTGGTGGCCCGATGA

Upstream 100 bases:

>100_bases
ACGCGGCGTACGAACCGCCCGCGGTGCTGGTCGACCTCGTCGCCGCCGGGCACCTCGGCAAGAAGTCCGGTCGTGGCTTC
TACGACTACGAGGCGCAGTC

Downstream 100 bases:

>100_bases
CCGCCGTCGCCGGCATGTCCCGAGCGCTCGCACGCGCGGAGTCGGCCAAGGCGCTCGACGTCGCCGAGGCCGTCGTACTC
CTGCAGGCACGCGGGGTGGA

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MSGLLRVGTRQGFDTLEIDSPTNRNALSVELLTALHDEVRRSATGTGRGLLVQHVGPAFCSGVDLKERAALGPDDSSHSE
LLAHLLRELWHYPKPVVVMVDGAVRGGGLGLLACADVVLATARSSFAYSESRVGVAPALVMAVTLPLADVRALVPRLLDG
AVFGAVTAHELGLVTRVVEDASKVSTVLSELRQGAPDAQRVIKTLARQRIGVDVDGLLVEMAGVSARLFAGAEAAEGVAA
FTSRRSPSWVVAR

Sequences:

>Translated_253_residues
MSGLLRVGTRQGFDTLEIDSPTNRNALSVELLTALHDEVRRSATGTGRGLLVQHVGPAFCSGVDLKERAALGPDDSSHSE
LLAHLLRELWHYPKPVVVMVDGAVRGGGLGLLACADVVLATARSSFAYSESRVGVAPALVMAVTLPLADVRALVPRLLDG
AVFGAVTAHELGLVTRVVEDASKVSTVLSELRQGAPDAQRVIKTLARQRIGVDVDGLLVEMAGVSARLFAGAEAAEGVAA
FTSRRSPSWVVAR
>Mature_252_residues
SGLLRVGTRQGFDTLEIDSPTNRNALSVELLTALHDEVRRSATGTGRGLLVQHVGPAFCSGVDLKERAALGPDDSSHSEL
LAHLLRELWHYPKPVVVMVDGAVRGGGLGLLACADVVLATARSSFAYSESRVGVAPALVMAVTLPLADVRALVPRLLDGA
VFGAVTAHELGLVTRVVEDASKVSTVLSELRQGAPDAQRVIKTLARQRIGVDVDGLLVEMAGVSARLFAGAEAAEGVAAF
TSRRSPSWVVAR

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI31542718, Length=256, Percent_Identity=26.171875, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI194097323, Length=248, Percent_Identity=26.2096774193548, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87082183, Length=201, Percent_Identity=26.3681592039801, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI221142681, Length=206, Percent_Identity=29.126213592233, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787660, Length=261, Percent_Identity=28.735632183908, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787659, Length=264, Percent_Identity=28.030303030303, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI25145438, Length=261, Percent_Identity=25.6704980842912, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=259, Percent_Identity=24.3243243243243, Blast_Score=64, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24653139, Length=254, Percent_Identity=28.3464566929134, Blast_Score=85, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 26545; Mature: 26414

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLLRVGTRQGFDTLEIDSPTNRNALSVELLTALHDEVRRSATGTGRGLLVQHVGPAFC
CCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHHCCHHHH
SGVDLKERAALGPDDSSHSELLAHLLRELWHYPKPVVVMVDGAVRGGGLGLLACADVVLA
CCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHH
TARSSFAYSESRVGVAPALVMAVTLPLADVRALVPRLLDGAVFGAVTAHELGLVTRVVED
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASKVSTVLSELRQGAPDAQRVIKTLARQRIGVDVDGLLVEMAGVSARLFAGAEAAEGVAA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHCCCHHHHHHHH
FTSRRSPSWVVAR
HHCCCCCCEEECC
>Mature Secondary Structure 
SGLLRVGTRQGFDTLEIDSPTNRNALSVELLTALHDEVRRSATGTGRGLLVQHVGPAFC
CCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEHHHCCHHHH
SGVDLKERAALGPDDSSHSELLAHLLRELWHYPKPVVVMVDGAVRGGGLGLLACADVVLA
CCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHH
TARSSFAYSESRVGVAPALVMAVTLPLADVRALVPRLLDGAVFGAVTAHELGLVTRVVED
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASKVSTVLSELRQGAPDAQRVIKTLARQRIGVDVDGLLVEMAGVSARLFAGAEAAEGVAA
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHCCCHHHHHHHH
FTSRRSPSWVVAR
HHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA