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The map label for this gene is add [H]

Identifier: 119714922

GI number: 119714922

Start: 712984

End: 714015

Strand: Reverse

Name: add [H]

Synonym: Noca_0674

Alternate gene names: 119714922

Gene position: 714015-712984 (Counterclockwise)

Preceding gene: 119714923

Following gene: 119714921

Centisome position: 14.32

GC content: 75.1

Gene sequence:

>1032_bases
ATGCGCGATCTCCACGAGCTCCCGAAGGCGCACCTGCACCTGCACTTCACCGGGTCGATGCGGCACTCGACGCTGCTCGA
GCTCGCGGAGAGGGACGGCATCGTGCTGCCCGACCAGCTCGTGGAGGACTGGCCGCCGCAGCTCTCGGCGGCCGACGAGA
AGGGCTGGTTCCGCTTCCAGCGGCTCTACGACGTCGCCCGGTCGGTGCTGCGCACGGAGGGCGACGTGCGCCGGCTGGTG
CTCGAGGCCGCGGAGGACGACGTCCGCGACGGCGGCCGCTGGCTGGAGATCCAGGTCGACCCCAGCGGCTACGCCGCCCG
CTTCGGCGGCATCACCGCCTTCACCGACCTGGTCCTGGACGCGGTCCGGGACGCCGAGCGGGCCACCGGCCTCGGCATGG
CGGTGGTGATCGCGGCCAACCGCACCCGCCACCCGCTCGACGCCCGGACGTTGGCCCGCCTGGCCGCGCAGTACGCCGGC
CGCGGGGTGGTCGGCTTCGGGCTCTCCAACGACGAGCGCCGCGGCAGCACCGCCGACTTCGCCCCGGCGTTCAGGATCGC
CGAGCGGGCCGGGCTGCTGCTCGCCCCCCACGGCGGCGAGCTGCGCGGGCCCGAGCACGTGCGGCTGTGCCTGGACGCCC
TGCACGCCGAGCGCCTCGGCCACGGGATCCGGTCGGCGGAGGACCCGGCCCTGCTGGACCGCATCGTCTCGGCGGGCGTC
GCGCTCGAGGTGTGCCCGGTCTCCAACGTCGCGCTCGGCGTGTACTCCGACCTGACCTCGGTGCCACTGCCCACCCTGCT
GGCGACCGGGGCGACCGTCGCGCTGGGAGCCGACGACCCGCTCCTGTTCGGCTCGCGGCTGGCCGGCCAGTACGCCACGA
TGCGCGCGGCCCACGACCTCACCGACACCCAGCTGGCCGAGCTGGCCCGGATGTCGGTGCGCGCCTCCCGGGCCCCCGGG
GACGTCCGGTCCCGTGTCCTTGCCGACATCGACGCCTGGCTCGGAGCCAGTCCTGCGACGATGGGGCCATGA

Upstream 100 bases:

>100_bases
CCCCACCCTCAGCGAGGTCACGGAGGCGATGGAAGCCGTCACGGTCTGCGTGCTGCTCGCCGCCTCCGAGAAGCTCCTCG
CCTGAGCCGCGCACCACCCG

Downstream 100 bases:

>100_bases
GCGACCCGAACCAGCCCGGCGAGCCGCAGCAGCCCTACCAGCAGCCCTACCAGCAGCCCTACGGCGCGGGGCAGTACCAG
CAGCCCTACCAGCCCGGGCC

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MRDLHELPKAHLHLHFTGSMRHSTLLELAERDGIVLPDQLVEDWPPQLSAADEKGWFRFQRLYDVARSVLRTEGDVRRLV
LEAAEDDVRDGGRWLEIQVDPSGYAARFGGITAFTDLVLDAVRDAERATGLGMAVVIAANRTRHPLDARTLARLAAQYAG
RGVVGFGLSNDERRGSTADFAPAFRIAERAGLLLAPHGGELRGPEHVRLCLDALHAERLGHGIRSAEDPALLDRIVSAGV
ALEVCPVSNVALGVYSDLTSVPLPTLLATGATVALGADDPLLFGSRLAGQYATMRAAHDLTDTQLAELARMSVRASRAPG
DVRSRVLADIDAWLGASPATMGP

Sequences:

>Translated_343_residues
MRDLHELPKAHLHLHFTGSMRHSTLLELAERDGIVLPDQLVEDWPPQLSAADEKGWFRFQRLYDVARSVLRTEGDVRRLV
LEAAEDDVRDGGRWLEIQVDPSGYAARFGGITAFTDLVLDAVRDAERATGLGMAVVIAANRTRHPLDARTLARLAAQYAG
RGVVGFGLSNDERRGSTADFAPAFRIAERAGLLLAPHGGELRGPEHVRLCLDALHAERLGHGIRSAEDPALLDRIVSAGV
ALEVCPVSNVALGVYSDLTSVPLPTLLATGATVALGADDPLLFGSRLAGQYATMRAAHDLTDTQLAELARMSVRASRAPG
DVRSRVLADIDAWLGASPATMGP
>Mature_343_residues
MRDLHELPKAHLHLHFTGSMRHSTLLELAERDGIVLPDQLVEDWPPQLSAADEKGWFRFQRLYDVARSVLRTEGDVRRLV
LEAAEDDVRDGGRWLEIQVDPSGYAARFGGITAFTDLVLDAVRDAERATGLGMAVVIAANRTRHPLDARTLARLAAQYAG
RGVVGFGLSNDERRGSTADFAPAFRIAERAGLLLAPHGGELRGPEHVRLCLDALHAERLGHGIRSAEDPALLDRIVSAGV
ALEVCPVSNVALGVYSDLTSVPLPTLLATGATVALGADDPLLFGSRLAGQYATMRAAHDLTDTQLAELARMSVRASRAPG
DVRSRVLADIDAWLGASPATMGP

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=355, Percent_Identity=26.4788732394366, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI29029552, Length=131, Percent_Identity=36.6412213740458, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI29029550, Length=131, Percent_Identity=36.6412213740458, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI61175224, Length=222, Percent_Identity=24.3243243243243, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787910, Length=333, Percent_Identity=29.7297297297297, Blast_Score=121, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17538512, Length=349, Percent_Identity=24.3553008595989, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI32565969, Length=348, Percent_Identity=24.4252873563218, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324188, Length=337, Percent_Identity=26.7062314540059, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24645260, Length=330, Percent_Identity=27.8787878787879, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006650
- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 36888; Mature: 36888

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00485 A_DEAMINASE ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDLHELPKAHLHLHFTGSMRHSTLLELAERDGIVLPDQLVEDWPPQLSAADEKGWFRFQ
CCCHHHCCHHEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCHHHHHHH
RLYDVARSVLRTEGDVRRLVLEAAEDDVRDGGRWLEIQVDPSGYAARFGGITAFTDLVLD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHCCHHHHHHHHHH
AVRDAERATGLGMAVVIAANRTRHPLDARTLARLAAQYAGRGVVGFGLSNDERRGSTADF
HHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCH
APAFRIAERAGLLLAPHGGELRGPEHVRLCLDALHAERLGHGIRSAEDPALLDRIVSAGV
HHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
ALEVCPVSNVALGVYSDLTSVPLPTLLATGATVALGADDPLLFGSRLAGQYATMRAAHDL
EEEECCCCCHHHHHHHHHHHCCHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCC
TDTQLAELARMSVRASRAPGDVRSRVLADIDAWLGASPATMGP
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRDLHELPKAHLHLHFTGSMRHSTLLELAERDGIVLPDQLVEDWPPQLSAADEKGWFRFQ
CCCHHHCCHHEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCHHHHHHH
RLYDVARSVLRTEGDVRRLVLEAAEDDVRDGGRWLEIQVDPSGYAARFGGITAFTDLVLD
HHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHCCHHHHHHHHHH
AVRDAERATGLGMAVVIAANRTRHPLDARTLARLAAQYAGRGVVGFGLSNDERRGSTADF
HHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCH
APAFRIAERAGLLLAPHGGELRGPEHVRLCLDALHAERLGHGIRSAEDPALLDRIVSAGV
HHHHHHHHHCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
ALEVCPVSNVALGVYSDLTSVPLPTLLATGATVALGADDPLLFGSRLAGQYATMRAAHDL
EEEECCCCCHHHHHHHHHHHCCHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCC
TDTQLAELARMSVRASRAPGDVRSRVLADIDAWLGASPATMGP
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8675024 [H]