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The map label for this gene is tmd [H]

Identifier: 119714872

GI number: 119714872

Start: 654931

End: 657102

Strand: Reverse

Name: tmd [H]

Synonym: Noca_0618

Alternate gene names: 119714872

Gene position: 657102-654931 (Counterclockwise)

Preceding gene: 119714873

Following gene: 119714868

Centisome position: 13.18

GC content: 63.12

Gene sequence:

>2172_bases
ATGACCATCGACCCGCGCCATGCGCCGCTGTTCGAACCGATCCAGGTCGGCCCCAAGATGTTCCGCAATCGGTTCTACGT
TTCCCCCCATTGCTCCGGTCTGGGTGTTGATTACCCCGGAGCTCAGGCCTATCTCCGGGGCATGCGCGCCGAGGGCGGCT
GGGCCGCGGTCAACACCGAGTACTGCGCGGTCGACGCGGAAAGCGACGATGCGCCTTGGGTCCAAGCCCGGCTCATAGAC
CACCGCGACGAGGCCAACCTCCGGCTCATGGTCGAGCGCGTCCACGAGTTCGGGGCATTGGCCGGCGTTCAGCTCGTCTA
CATGGGCCCCGATCACACTGGTTTTGTGACGCGGCTTCCGGCAGGTGGGCCCTCGCAGGTCACCAGCGCGTTGTCTGGTC
ACTCGTGCTACGAGATGAACAAGAGCGACATCCGCCGAATTCAGAAGGCATACGTCGACGCTGCCATCCGGGCCCGCAAC
ATCGGGTTCGATCTAGTCCAGGTTTCCGCTCGGGCAAGTTTCTCGCTCCCCCTGCAGTTCCTCTGGCGCCACTGGAACCA
CCGCACCGACGAGTACGGCGGGTCCATCGAAAACCGCACCAGGTTCTGGCGCGAGACGATCGAGCAGGTTCGTGAGGCCG
TTGGCGACGACTGCGCCATCGTGGCGGGCTTCTGCCTTGACTCGTTCACCGATGAGTCCGATCGGGCCTTCAGGGTTAAC
GAGGACGGCGTCGCGGTAGTCGAACTCCTGGATGACATGGTCGACCTTTGGGACATGCAGGTCGGATCCATGACCGACGA
CGCGAGCTCGTCGCGGTTCTTCGAACCGTTCTGGCAGCGCGAATACATCGAACAGGTCCGGCCGTACGCCAAGAAGCCCA
TCGCAGCTGTGGGTCGGTTCACCGACCCGGAACTGATGGCACGAGTAGTGAGGGACGGGGTCATCGACATCATCGCGGCA
GCGCGTCCCGCAATTGCTGATCCCTTCATCCCGACGAAGATCCGGGAGGGACGTGGCGAAGACATTCGTGAGTGCATCGG
CTGCAACATCTGCGTCTCCCGTTTCAACAACGGGGGTGGTCGGATCGTGTGCACTCAGAACGCGACCGTGGGCGAGGAGT
ATCGGCGGGGCTGGCATCCGGAGAAGTTCAATGCTTCGCCTCGTGCTGAGGAGCCCATTCTGATTGTCGGCGCTGGCCCA
GCCGGGCTGGAGTGTGCTCGGGTGCTGGGAGAACGTGGATTCCACAACGTTCATCTTGTCGACAAGGACGCGGAGGTCGG
CGGCCACGTCAACTGGGTGTCCCAGTTGCCGGGGCTACGCACTTGGCGGCGTGTCGTCGAATACCGCGAGGCACAGCTGT
CGAAGCTCAACAACGTCACCGTGCTGACCAACCAGCCCATGGATGTCGAGGCCATCCTAGACTACGGAGCCCAGACCGTT
GTGGTCGCCACCGGAGCCGAATGGGACGCCACCGGGAACAACCCGATCACCCACGCTCCGATTGACGGTGCCAAGGACCA
CCGACAGATGGTGTTTACGCCCGAGTCCATCATGATCGAGCAACGACAAGGCCTCGGCGACAGGGTGGTCGTGTATGACT
GCGACGGCTACTACATGGGCTCCAGCATCGCCGAGAGGCTGGCGGCACAAGGCAAGAAGGTCACGCTCGTCTGCCCGGGT
GACCAGGTCGGCTCGTACCTGTTCTACACCGACGAGGGCGAGCGAATGGTGCACAGTCTGCTTGAACTCGGCGTCGAAGT
TGTGCCGAGTCATGTGGTGACGTCGATCAGGCCCGGCTTGGTGACAGGCCACCACAGTTACCACTCCGGCCTGACAGCCA
CCTGGCCGGCAAGCAGCATCGTGCTCGTAACCCAGCGTCGTTCCCGCAGCGGGCTGTACGATGAACTCACAGGCCAGGCC
GAAGTTCTCCGTGAGAACGGCATCGAGGTCTTTCGCATTGGCGACTGTGTAGAGCCACGAGTTATCGCCGAAGCAGTCTT
TGACGGTCACCGGCTGGCCCGCGAGATCGATGCGCCGGACCCGGCCACCCCGCTGCCCTTCATTCGGGAGCAGCGAATCC
TTGGATGGCGCGAGGAGGACTACGACGGCGAGCTCGTTCACCGACTCCCCCTGGCGCCAACATCGAAGACCAGCGCCCCT
GCCACGCCATGA

Upstream 100 bases:

>100_bases
GAGTCAGGCCGATTCAGACCGACCGTATCCAGCAGAAGGCGACACTGAACTTGGTCCAACCTGACAAAGTGCCCGCAGAG
AATCCGGCTAGGTTCCGACC

Downstream 100 bases:

>100_bases
GCGCCGAAACCAGCTCCCAAAGGATGGCTGAGATGGTCGACATCCATGTCAACGGCTGACCATTACGAGACCCTCTTCGA
CCCAGTCGTCATCGGGCCCA

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: TMADh [H]

Number of amino acids: Translated: 723; Mature: 722

Protein sequence:

>723_residues
MTIDPRHAPLFEPIQVGPKMFRNRFYVSPHCSGLGVDYPGAQAYLRGMRAEGGWAAVNTEYCAVDAESDDAPWVQARLID
HRDEANLRLMVERVHEFGALAGVQLVYMGPDHTGFVTRLPAGGPSQVTSALSGHSCYEMNKSDIRRIQKAYVDAAIRARN
IGFDLVQVSARASFSLPLQFLWRHWNHRTDEYGGSIENRTRFWRETIEQVREAVGDDCAIVAGFCLDSFTDESDRAFRVN
EDGVAVVELLDDMVDLWDMQVGSMTDDASSSRFFEPFWQREYIEQVRPYAKKPIAAVGRFTDPELMARVVRDGVIDIIAA
ARPAIADPFIPTKIREGRGEDIRECIGCNICVSRFNNGGGRIVCTQNATVGEEYRRGWHPEKFNASPRAEEPILIVGAGP
AGLECARVLGERGFHNVHLVDKDAEVGGHVNWVSQLPGLRTWRRVVEYREAQLSKLNNVTVLTNQPMDVEAILDYGAQTV
VVATGAEWDATGNNPITHAPIDGAKDHRQMVFTPESIMIEQRQGLGDRVVVYDCDGYYMGSSIAERLAAQGKKVTLVCPG
DQVGSYLFYTDEGERMVHSLLELGVEVVPSHVVTSIRPGLVTGHHSYHSGLTATWPASSIVLVTQRRSRSGLYDELTGQA
EVLRENGIEVFRIGDCVEPRVIAEAVFDGHRLAREIDAPDPATPLPFIREQRILGWREEDYDGELVHRLPLAPTSKTSAP
ATP

Sequences:

>Translated_723_residues
MTIDPRHAPLFEPIQVGPKMFRNRFYVSPHCSGLGVDYPGAQAYLRGMRAEGGWAAVNTEYCAVDAESDDAPWVQARLID
HRDEANLRLMVERVHEFGALAGVQLVYMGPDHTGFVTRLPAGGPSQVTSALSGHSCYEMNKSDIRRIQKAYVDAAIRARN
IGFDLVQVSARASFSLPLQFLWRHWNHRTDEYGGSIENRTRFWRETIEQVREAVGDDCAIVAGFCLDSFTDESDRAFRVN
EDGVAVVELLDDMVDLWDMQVGSMTDDASSSRFFEPFWQREYIEQVRPYAKKPIAAVGRFTDPELMARVVRDGVIDIIAA
ARPAIADPFIPTKIREGRGEDIRECIGCNICVSRFNNGGGRIVCTQNATVGEEYRRGWHPEKFNASPRAEEPILIVGAGP
AGLECARVLGERGFHNVHLVDKDAEVGGHVNWVSQLPGLRTWRRVVEYREAQLSKLNNVTVLTNQPMDVEAILDYGAQTV
VVATGAEWDATGNNPITHAPIDGAKDHRQMVFTPESIMIEQRQGLGDRVVVYDCDGYYMGSSIAERLAAQGKKVTLVCPG
DQVGSYLFYTDEGERMVHSLLELGVEVVPSHVVTSIRPGLVTGHHSYHSGLTATWPASSIVLVTQRRSRSGLYDELTGQA
EVLRENGIEVFRIGDCVEPRVIAEAVFDGHRLAREIDAPDPATPLPFIREQRILGWREEDYDGELVHRLPLAPTSKTSAP
ATP
>Mature_722_residues
TIDPRHAPLFEPIQVGPKMFRNRFYVSPHCSGLGVDYPGAQAYLRGMRAEGGWAAVNTEYCAVDAESDDAPWVQARLIDH
RDEANLRLMVERVHEFGALAGVQLVYMGPDHTGFVTRLPAGGPSQVTSALSGHSCYEMNKSDIRRIQKAYVDAAIRARNI
GFDLVQVSARASFSLPLQFLWRHWNHRTDEYGGSIENRTRFWRETIEQVREAVGDDCAIVAGFCLDSFTDESDRAFRVNE
DGVAVVELLDDMVDLWDMQVGSMTDDASSSRFFEPFWQREYIEQVRPYAKKPIAAVGRFTDPELMARVVRDGVIDIIAAA
RPAIADPFIPTKIREGRGEDIRECIGCNICVSRFNNGGGRIVCTQNATVGEEYRRGWHPEKFNASPRAEEPILIVGAGPA
GLECARVLGERGFHNVHLVDKDAEVGGHVNWVSQLPGLRTWRRVVEYREAQLSKLNNVTVLTNQPMDVEAILDYGAQTVV
VATGAEWDATGNNPITHAPIDGAKDHRQMVFTPESIMIEQRQGLGDRVVVYDCDGYYMGSSIAERLAAQGKKVTLVCPGD
QVGSYLFYTDEGERMVHSLLELGVEVVPSHVVTSIRPGLVTGHHSYHSGLTATWPASSIVLVTQRRSRSGLYDELTGQAE
VLRENGIEVFRIGDCVEPRVIAEAVFDGHRLAREIDAPDPATPLPFIREQRILGWREEDYDGELVHRLPLAPTSKTSAPA
TP

Specific function: Catalyzes The NADP-Dependent Reduction Of 2,4-Dienoyl- CoA To Yield Trans-2- Enoyl-CoA. [C]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=566, Percent_Identity=26.5017667844523, Blast_Score=141, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17559804, Length=271, Percent_Identity=27.6752767527675, Blast_Score=79, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17559802, Length=193, Percent_Identity=30.0518134715026, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6325086, Length=236, Percent_Identity=27.5423728813559, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321973, Length=375, Percent_Identity=24.5333333333333, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.5.8.2 [H]

Molecular weight: Translated: 80324; Mature: 80193

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDPRHAPLFEPIQVGPKMFRNRFYVSPHCSGLGVDYPGAQAYLRGMRAEGGWAAVNTE
CCCCCCCCCCCCHHHHCHHHHHCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCEEEECCE
YCAVDAESDDAPWVQARLIDHRDEANLRLMVERVHEFGALAGVQLVYMGPDHTGFVTRLP
EEEEECCCCCCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEECC
AGGPSQVTSALSGHSCYEMNKSDIRRIQKAYVDAAIRARNIGFDLVQVSARASFSLPLQF
CCCHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHH
LWRHWNHRTDEYGGSIENRTRFWRETIEQVREAVGDDCAIVAGFCLDSFTDESDRAFRVN
HHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCCCEEEEC
EDGVAVVELLDDMVDLWDMQVGSMTDDASSSRFFEPFWQREYIEQVRPYAKKPIAAVGRF
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCC
TDPELMARVVRDGVIDIIAAARPAIADPFIPTKIREGRGEDIRECIGCNICVSRFNNGGG
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCHHHHHHHCCHHEEEEECCCCC
RIVCTQNATVGEEYRRGWHPEKFNASPRAEEPILIVGAGPAGLECARVLGERGFHNVHLV
EEEEECCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEE
DKDAEVGGHVNWVSQLPGLRTWRRVVEYREAQLSKLNNVTVLTNQPMDVEAILDYGAQTV
CCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCEE
VVATGAEWDATGNNPITHAPIDGAKDHRQMVFTPESIMIEQRQGLGDRVVVYDCDGYYMG
EEEECCCCCCCCCCCCEECCCCCCCCCCEEEECCHHHHHHHHCCCCCEEEEEECCCEECC
SSIAERLAAQGKKVTLVCPGDQVGSYLFYTDEGERMVHSLLELGVEVVPSHVVTSIRPGL
HHHHHHHHHCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VTGHHSYHSGLTATWPASSIVLVTQRRSRSGLYDELTGQAEVLRENGIEVFRIGDCVEPR
EECCCHHCCCCEEECCCCEEEEEECCCCCCCCHHHHCCHHHHHHHCCCEEEEECCCCCHH
VIAEAVFDGHRLAREIDAPDPATPLPFIREQRILGWREEDYDGELVHRLPLAPTSKTSAP
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHEECCCCCCCCCCCC
ATP
CCC
>Mature Secondary Structure 
TIDPRHAPLFEPIQVGPKMFRNRFYVSPHCSGLGVDYPGAQAYLRGMRAEGGWAAVNTE
CCCCCCCCCCCHHHHCHHHHHCEEEECCCCCCCCCCCCCHHHHHHHCCCCCCEEEECCE
YCAVDAESDDAPWVQARLIDHRDEANLRLMVERVHEFGALAGVQLVYMGPDHTGFVTRLP
EEEEECCCCCCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEECC
AGGPSQVTSALSGHSCYEMNKSDIRRIQKAYVDAAIRARNIGFDLVQVSARASFSLPLQF
CCCHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHH
LWRHWNHRTDEYGGSIENRTRFWRETIEQVREAVGDDCAIVAGFCLDSFTDESDRAFRVN
HHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCCCEEEEC
EDGVAVVELLDDMVDLWDMQVGSMTDDASSSRFFEPFWQREYIEQVRPYAKKPIAAVGRF
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCC
TDPELMARVVRDGVIDIIAAARPAIADPFIPTKIREGRGEDIRECIGCNICVSRFNNGGG
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCHHHHHHHCCHHEEEEECCCCC
RIVCTQNATVGEEYRRGWHPEKFNASPRAEEPILIVGAGPAGLECARVLGERGFHNVHLV
EEEEECCCCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEE
DKDAEVGGHVNWVSQLPGLRTWRRVVEYREAQLSKLNNVTVLTNQPMDVEAILDYGAQTV
CCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHCCCCEE
VVATGAEWDATGNNPITHAPIDGAKDHRQMVFTPESIMIEQRQGLGDRVVVYDCDGYYMG
EEEECCCCCCCCCCCCEECCCCCCCCCCEEEECCHHHHHHHHCCCCCEEEEEECCCEECC
SSIAERLAAQGKKVTLVCPGDQVGSYLFYTDEGERMVHSLLELGVEVVPSHVVTSIRPGL
HHHHHHHHHCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VTGHHSYHSGLTATWPASSIVLVTQRRSRSGLYDELTGQAEVLRENGIEVFRIGDCVEPR
EECCCHHCCCCEEECCCCEEEEEECCCCCCCCHHHHCCHHHHHHHCCCEEEEECCCCCHH
VIAEAVFDGHRLAREIDAPDPATPLPFIREQRILGWREEDYDGELVHRLPLAPTSKTSAP
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHEECCCCCCCCCCCC
ATP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1505666; 620783; 1551870; 12567183 [H]