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The map label for this gene is hflC [H]

Identifier: 119386379

GI number: 119386379

Start: 820071

End: 821180

Strand: Direct

Name: hflC [H]

Synonym: Pden_3671

Alternate gene names: 119386379

Gene position: 820071-821180 (Clockwise)

Preceding gene: 119386378

Following gene: 119386381

Centisome position: 47.4

GC content: 70.81

Gene sequence:

>1110_bases
ATGAACCGTGTAATCTCGCTTCTGGCGCTGCCCTTCCTGGTCGTGGTGGCGGTCCTGGTGGTCTCGGCGCTCTATATCGT
CGACGTGCGTGAAAAGGCCCTTGTCCTGCGCTTCGGCGAGGTGGTCGAGGTGCGCGAGGAACCGGGCCTTGGCATCAAGG
TGCCCTTCCTCGACAATGTGGTGAAATACGATGCCCGCATTCTCGGCCTGCCGACCCCGCCGATGGAGGTTACGCCGCTG
GACGACCGCCGGCTGGTGGTCGACGCCTTTGCGCGCTGGCAGATCACCGATGTGGTGCAGTTCCGTCGCGCGGTGGGCTC
GGGCGGCATCGAGTTCGCGCAGCGCCGGCTGGAGCCGATCGTGACCAACGCGATCCGGCAGGTGCTGGGCTCGGTGCCCT
CGACCACGGTGCTGTCGGACGACCGGACGCCGCTGATGAACCGCATCCGCGACCTGTCGCGCGACGATGCCCGCGACCTG
GGCATTCGCGTCATCGACGTGCGCCTGACCCGCACCGACCTGCCCGAGCAGAACCTGACCGCGACCTATGCGAGGATGCG
GGCCGAGCGCGAGCGCGAGGCTGCCGACGAGATCGCCCGCGGCGGCGAGGCCGCGCAGCGTGTCCGTGCTGCCGCCGACC
GCACCGTGGTCGAGCTGACCTCCGAGGCGCGCAAGCGGGCCGAGGTGGTGCGCGGCGAAGCCGATGCCCGCCGCAACGCC
ATCTATGCCGGTGCCTTCGGCCGCGATCCCGAGTTCTTTGCCTTCACCCGCTCGATGACCTCCTACGAGCGGGCGCTGCG
GGGCGAGAACAGCTCGCTGGTGATCCAGCCGCAGGGCGAGTTCTTCGACTACCTGCGCAACGACGGGGCCGACCGGGCCA
ATCCGGTGCCGGTGCCCCAGCCGGCTTCGGACGCCACGCCTTCGGACGACGAGTCCGAGACCCAAGGCGCGCTTGAGCCC
GGCGAGGCAGTGGCCCCGGCCGAGACCACGCGCGAGGGCGAGCCGCTGGGCGCCGGTGCCGGCGTGACGCTGACGCCGCT
GCCCGAATCCCTGGCCGCGCCGCCGCAGGAAGAGCCTGTGGTGCCCCCGGCGCCGCTTCCGGCGGACTGA

Upstream 100 bases:

>100_bases
TCGACGGCGAGGCCGGGCAGGGCGTCGTGCCCTATCTGCCGCTGGATCAGCTGCGCAGCGGGGCTGCGGGCGCTCGCAAC
ACCGAGGGGGGGAACCAGTG

Downstream 100 bases:

>100_bases
TCCGGGCGCGGGCCCGGGACGGGAAACCGGCCGGAACAGGAAAGCGCAACAGGAAAGGCGGGACGCATCTGCGCCCCGCC
TTTTTTCATGTCTCGGCACT

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MNRVISLLALPFLVVVAVLVVSALYIVDVREKALVLRFGEVVEVREEPGLGIKVPFLDNVVKYDARILGLPTPPMEVTPL
DDRRLVVDAFARWQITDVVQFRRAVGSGGIEFAQRRLEPIVTNAIRQVLGSVPSTTVLSDDRTPLMNRIRDLSRDDARDL
GIRVIDVRLTRTDLPEQNLTATYARMRAEREREAADEIARGGEAAQRVRAAADRTVVELTSEARKRAEVVRGEADARRNA
IYAGAFGRDPEFFAFTRSMTSYERALRGENSSLVIQPQGEFFDYLRNDGADRANPVPVPQPASDATPSDDESETQGALEP
GEAVAPAETTREGEPLGAGAGVTLTPLPESLAAPPQEEPVVPPAPLPAD

Sequences:

>Translated_369_residues
MNRVISLLALPFLVVVAVLVVSALYIVDVREKALVLRFGEVVEVREEPGLGIKVPFLDNVVKYDARILGLPTPPMEVTPL
DDRRLVVDAFARWQITDVVQFRRAVGSGGIEFAQRRLEPIVTNAIRQVLGSVPSTTVLSDDRTPLMNRIRDLSRDDARDL
GIRVIDVRLTRTDLPEQNLTATYARMRAEREREAADEIARGGEAAQRVRAAADRTVVELTSEARKRAEVVRGEADARRNA
IYAGAFGRDPEFFAFTRSMTSYERALRGENSSLVIQPQGEFFDYLRNDGADRANPVPVPQPASDATPSDDESETQGALEP
GEAVAPAETTREGEPLGAGAGVTLTPLPESLAAPPQEEPVVPPAPLPAD
>Mature_369_residues
MNRVISLLALPFLVVVAVLVVSALYIVDVREKALVLRFGEVVEVREEPGLGIKVPFLDNVVKYDARILGLPTPPMEVTPL
DDRRLVVDAFARWQITDVVQFRRAVGSGGIEFAQRRLEPIVTNAIRQVLGSVPSTTVLSDDRTPLMNRIRDLSRDDARDL
GIRVIDVRLTRTDLPEQNLTATYARMRAEREREAADEIARGGEAAQRVRAAADRTVVELTSEARKRAEVVRGEADARRNA
IYAGAFGRDPEFFAFTRSMTSYERALRGENSSLVIQPQGEFFDYLRNDGADRANPVPVPQPASDATPSDDESETQGALEP
GEAVAPAETTREGEPLGAGAGVTLTPLPESLAAPPQEEPVVPPAPLPAD

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=309, Percent_Identity=29.126213592233, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1786697, Length=290, Percent_Identity=26.8965517241379, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 40307; Mature: 40307

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVISLLALPFLVVVAVLVVSALYIVDVREKALVLRFGEVVEVREEPGLGIKVPFLDNV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHH
VKYDARILGLPTPPMEVTPLDDRRLVVDAFARWQITDVVQFRRAVGSGGIEFAQRRLEPI
HHHCCEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VTNAIRQVLGSVPSTTVLSDDRTPLMNRIRDLSRDDARDLGIRVIDVRLTRTDLPEQNLT
HHHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCCCCHHHCCEEEEEEEEECCCCCCCHHH
ATYARMRAEREREAADEIARGGEAAQRVRAAADRTVVELTSEARKRAEVVRGEADARRNA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCE
IYAGAFGRDPEFFAFTRSMTSYERALRGENSSLVIQPQGEFFDYLRNDGADRANPVPVPQ
EEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCC
PASDATPSDDESETQGALEPGEAVAPAETTREGEPLGAGAGVTLTPLPESLAAPPQEEPV
CCCCCCCCCCCHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCEECCCCHHHCCCCCCCCC
VPPAPLPAD
CCCCCCCCC
>Mature Secondary Structure
MNRVISLLALPFLVVVAVLVVSALYIVDVREKALVLRFGEVVEVREEPGLGIKVPFLDNV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHH
VKYDARILGLPTPPMEVTPLDDRRLVVDAFARWQITDVVQFRRAVGSGGIEFAQRRLEPI
HHHCCEEECCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VTNAIRQVLGSVPSTTVLSDDRTPLMNRIRDLSRDDARDLGIRVIDVRLTRTDLPEQNLT
HHHHHHHHHCCCCCCEEECCCCCHHHHHHHHCCCCCHHHCCEEEEEEEEECCCCCCCHHH
ATYARMRAEREREAADEIARGGEAAQRVRAAADRTVVELTSEARKRAEVVRGEADARRNA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCE
IYAGAFGRDPEFFAFTRSMTSYERALRGENSSLVIQPQGEFFDYLRNDGADRANPVPVPQ
EEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCC
PASDATPSDDESETQGALEPGEAVAPAETTREGEPLGAGAGVTLTPLPESLAAPPQEEPV
CCCCCCCCCCCHHHCCCCCCCCCCCCCHHCCCCCCCCCCCCCEECCCCHHHCCCCCCCCC
VPPAPLPAD
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]