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The map label for this gene is fabG [H]

Identifier: 119386248

GI number: 119386248

Start: 686155

End: 686913

Strand: Direct

Name: fabG [H]

Synonym: Pden_3537

Alternate gene names: 119386248

Gene position: 686155-686913 (Clockwise)

Preceding gene: 119386245

Following gene: 119386249

Centisome position: 39.66

GC content: 70.09

Gene sequence:

>759_bases
ATGTCTGGAATCGTGCTTGTCACCGGCGCCGCCGGTGGCATCGGGGAAGCTGTTTGTCATCGCCTGGCTCAGGACGGCTT
TGCGGTCCTTGCCACGGACCTGTCGCAGGAGGCGGCGGAGCGGGTCGCGGATACGCTGCCGGGGCGGGGCCATCGGGCCA
TCGCGCTGGATGTCGCGAACGAAGCCGCGGTGATCTCGGCCTTCGCCGAGGCCGGGTCGCTGGGCCGGCCCATCGACCAT
GTGGTCGCCGCCGCCGGGATCCTGCTGTTCGCCGCCAATGGCGACCGCCCGCCGATCACCGACATCCAGCTGGCCGACTG
GGAGCGGACGCAGGCCGTCAACTCCACCGGCACCTTCCTTCTGCTGCGGGAATATCTGCGTGGCGCCAGCCGCCGGGCCA
TGGCGGGCGGACGTTTCGTGGGCTTTGCCTCGGTGGCGGCCCAGCTTGGCGGCTATCGCTCCAGCTCGGCCTATATCGCC
TCGAAGGGGGCGGTGATGGCGCTGGTCAAGGCCGGCGCGCGCGAGGCGGCAAACCTGGGCATTACCGTGAATGCGGTGGC
GCCGGGCCTGATCGATGCGCCGATGCTGCGGCAGTCGCTGCCGCCGGAACGGGACGCGACGGTCGCGGCCAACATTCCGC
TGAACCGCATCGGCACGCCGCAGGACGTGGCGGGGGCGGTGTCGTTCCTGATGGGGCCGGATGCGGCATACATCACCGGC
GCCGTCGTCGACGTGAACGGCGGCTATCGCATGCAATGA

Upstream 100 bases:

>100_bases
ATAAAATGTATCCAAAAACTGTATCTGATGCAGATTCTCTTTGCAATAACCACAGGAATGTGTTCATTACGTTTGCAACG
AGAGGGAGGAGCCTCAAGCC

Downstream 100 bases:

>100_bases
CGCCGGGGAGGACGTGATGGTCAAGCTGACGGAAAAACTGACGCATCTTCTGGGATGGATAGCGGGGGTGACGGTTCTGC
TGATGATGTTCCACGTCATG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSGIVLVTGAAGGIGEAVCHRLAQDGFAVLATDLSQEAAERVADTLPGRGHRAIALDVANEAAVISAFAEAGSLGRPIDH
VVAAAGILLFAANGDRPPITDIQLADWERTQAVNSTGTFLLLREYLRGASRRAMAGGRFVGFASVAAQLGGYRSSSAYIA
SKGAVMALVKAGAREAANLGITVNAVAPGLIDAPMLRQSLPPERDATVAANIPLNRIGTPQDVAGAVSFLMGPDAAYITG
AVVDVNGGYRMQ

Sequences:

>Translated_252_residues
MSGIVLVTGAAGGIGEAVCHRLAQDGFAVLATDLSQEAAERVADTLPGRGHRAIALDVANEAAVISAFAEAGSLGRPIDH
VVAAAGILLFAANGDRPPITDIQLADWERTQAVNSTGTFLLLREYLRGASRRAMAGGRFVGFASVAAQLGGYRSSSAYIA
SKGAVMALVKAGAREAANLGITVNAVAPGLIDAPMLRQSLPPERDATVAANIPLNRIGTPQDVAGAVSFLMGPDAAYITG
AVVDVNGGYRMQ
>Mature_251_residues
SGIVLVTGAAGGIGEAVCHRLAQDGFAVLATDLSQEAAERVADTLPGRGHRAIALDVANEAAVISAFAEAGSLGRPIDHV
VAAAGILLFAANGDRPPITDIQLADWERTQAVNSTGTFLLLREYLRGASRRAMAGGRFVGFASVAAQLGGYRSSSAYIAS
KGAVMALVKAGAREAANLGITVNAVAPGLIDAPMLRQSLPPERDATVAANIPLNRIGTPQDVAGAVSFLMGPDAAYITGA
VVDVNGGYRMQ

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=268, Percent_Identity=34.7014925373134, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=33.0708661417323, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI40254992, Length=254, Percent_Identity=35.0393700787402, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI126723750, Length=257, Percent_Identity=31.9066147859922, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=31.7647058823529, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI66933014, Length=235, Percent_Identity=26.3829787234043, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI5031737, Length=258, Percent_Identity=31.0077519379845, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=28.2352941176471, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI83715985, Length=255, Percent_Identity=29.8039215686275, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=27.6422764227642, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=34.8, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787335, Length=248, Percent_Identity=33.0645161290323, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=34.4961240310078, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1789057, Length=267, Percent_Identity=28.4644194756554, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=29.9595141700405, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=29.9595141700405, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=31.7073170731707, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788459, Length=258, Percent_Identity=31.3953488372093, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=29.296875, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=29.8804780876494, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=31.25, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787820, Length=227, Percent_Identity=27.7533039647577, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=253, Percent_Identity=31.6205533596838, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=30.1204819277108, Blast_Score=114, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=32.295719844358, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=260, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=254, Percent_Identity=28.3464566929134, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=31.0483870967742, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=32.8125, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=29.7619047619048, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24643142, Length=251, Percent_Identity=27.4900398406374, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI23397609, Length=250, Percent_Identity=28.4, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25721; Mature: 25589

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGIVLVTGAAGGIGEAVCHRLAQDGFAVLATDLSQEAAERVADTLPGRGHRAIALDVAN
CCCEEEEECCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCEEEEEEECC
EAAVISAFAEAGSLGRPIDHVVAAAGILLFAANGDRPPITDIQLADWERTQAVNSTGTFL
CHHHHHHHHHCCCCCCCHHHHHHHHCEEEEEECCCCCCCCCEEECCCHHHHHCCCCCHHH
LLREYLRGASRRAMAGGRFVGFASVAAQLGGYRSSSAYIASKGAVMALVKAGAREAANLG
HHHHHHCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHCCHHHHCCC
ITVNAVAPGLIDAPMLRQSLPPERDATVAANIPLNRIGTPQDVAGAVSFLMGPDAAYITG
EEEEECCCCCCCHHHHHHCCCCCCCCEEEECCCHHCCCCCHHHHHHHHHHHCCCCHHEEE
AVVDVNGGYRMQ
EEEECCCCEECC
>Mature Secondary Structure 
SGIVLVTGAAGGIGEAVCHRLAQDGFAVLATDLSQEAAERVADTLPGRGHRAIALDVAN
CCEEEEECCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCEEEEEEECC
EAAVISAFAEAGSLGRPIDHVVAAAGILLFAANGDRPPITDIQLADWERTQAVNSTGTFL
CHHHHHHHHHCCCCCCCHHHHHHHHCEEEEEECCCCCCCCCEEECCCHHHHHCCCCCHHH
LLREYLRGASRRAMAGGRFVGFASVAAQLGGYRSSSAYIASKGAVMALVKAGAREAANLG
HHHHHHCCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHCCHHHHCCC
ITVNAVAPGLIDAPMLRQSLPPERDATVAANIPLNRIGTPQDVAGAVSFLMGPDAAYITG
EEEEECCCCCCCHHHHHHCCCCCCCCEEEECCCHHCCCCCHHHHHHHHHHHCCCCHHEEE
AVVDVNGGYRMQ
EEEECCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]