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The map label for this gene is zraS [C]

Identifier: 119357351

GI number: 119357351

Start: 1758925

End: 1761396

Strand: Reverse

Name: zraS [C]

Synonym: Cpha266_1549

Alternate gene names: 119357351

Gene position: 1761396-1758925 (Counterclockwise)

Preceding gene: 119357356

Following gene: 119357350

Centisome position: 56.2

GC content: 46.52

Gene sequence:

>2472_bases
ATGCATGAAGATAATAACAAACGTGAAGCTCTTTCTGGTTCTCCGGTCATAATGAATGCCGAACAGGTTTATGCAATAAG
CCGCCAACAACTGCAGCTTTTTATGTCGGCAACTCATGCGGGCATATGGGAGTGGGATACGGTTACAAACAGCGTCATCT
GGTCAGATGAAGTGTGGGCGCTCTATGGACTGAACGCTTCTTGCTGCGATGCGACGTTCGAGGCATGGCTGAGTTCAGTT
CATCCTGAGGATAGAGAAAAAACCGAGAAAACTGTTTTGGGGGCCGCCAGAGACGATGTTGCATTTGAAGTAGCCTGGAG
AAGCCGTGATCTTGACGGCAATGAGCGCTGGCTTATGTCCAAAGGTTTTCCGTTAAGGGATGGCGCAGGACGCACCGGGA
GATATGTCGGTATCGTTCTGGATATTACCGATCGCAAGCAGGCTGAAGATGCGCTGTGTGAGAGCGAAGATCGTTTCAGA
AAACTTTTTGAAAGCCTTTCTGAAATCAAGCTGATTATCGACTCCCATTCAGGCAAAATTATTGACGCCAATCAGGCTGC
GGTGGATTTTTATGGCTGGTCGATTGAAGAGCTGACATCGATGAATATTGAGCAAATCAATACGACTTCATCTGAATTGG
TGACTCTGGATACTGAGAAATGCGGATCATTGCATCAGTCATGCGTTTCATTTCGTCATCGGAGGGCGGATGGTTCAATC
CGTGATGTGGAGGTATTCAGCAATAATATTGAAATTGCCGGAAATATACTGTATTATTCCACTATTCATGATGTTACCGA
GAGAAAACGATTCGAAGCCCTGACAGCATTTCGCCTTCGTCTTCTCGATATGGCTGAAAACCGCTCGGTTGAAGAGTTGC
TTAAAGCCACTCTCGATGAATCCGAATGCATGACCGAAAGCTCATTCAGCTTCTGCTGTTTTCTCATGGATGAACGTTCT
TCACCAACTTTGCAGGTGTTATCAACCAGTACGGAAAAGGCTATGAGCCTGATGAACAGGAATCAGGAAGTTTTTTCTCA
ATTGAGTGAAAGTTCGATATGGAGCGCGGCCATTCTTGAAAAAAAAGCCGTGATTCACAATGATGTCGAGAGAGATCTGC
CCGAAGATCACCCCTTCTTCAAGCGTAAACTGGTGGTTCCTATTGTGCAGGGTGATACGGTAATGGCTATTATCGGGGTT
GGAAACAAACAGTATCCCTATGATGAGGATGATGCCCGATGGGTTGGAACTCTTGCTGATGTCGCATGGGATATCGTTGC
TCGCAAGCGTGCCGAATTGTCTGAAAAGAACACGCAGGAGGCTTTGAGCCAGTCACAAAAGATGGAAATGGTTGGACGGC
TTGCCGGTGGTATAGCCCACGATTTCAACAATATGCTTGGGGTGATTCTCGGGCATACGGAAATAGCTCTTGAACAGCTT
GATCCTTCCGAATCGGCTTATGCGGATCTTGAAGCAATTCGAAAAGCCGCAGCACGTTCGGCGGGCTTGATCCGTCAACT
GCTTGCTTTTGCAAGAAAGCAGACCGTGATGCCGAAAATTATTTCGTTGAATACGATGGTTGAAGGGATGCTCACCATGA
TGCGGCGCTTGATTGGTGAAAATATTACCCTTGTCTGGATACCTGAAAATCAGAATGCCAAGATCAAGATCGATCCATCA
CAGATCGATCAGATACTTGCCAACCTTTGTGTCAATGCTCGTGACTCTATTGTCGGAGGAGGGAGAATTACCATTGAAAC
CGGCAGGCTGTGCGTGCAGAGAAACGAAAACACAGCCAACCATCCATGCAGGATACCCGGAGACTATGTGACGCTTGCGG
TTACCGATAATGGCAGCGGGATCGACAAGAAGCATCTCCCGCATATTTTCGAGCCGTTTTTTACCACCAAGGAACAAGGG
AAAGGGACGGGTCTCGGGTTATCTACGGTTTATGGTATTGTCAAACAGAATAACGGTTGTATTGACTGTCAGAGTGAGCC
TGGTAAAGGGACATGCATCAAAATTCACTTGCCGAGGTATATCGATAAAGCCGATTCGGTACCGGTAGAGACGCCCGAGC
AGAGTATTACAAGAGGGAAGGAGACGATACTCCTTGTTGAAGATGAACCTGATATTCTTAAACTTTGCAAGCTGATGCTT
GAGAATAATGGTTATACGGTACTTTCAGCCGATACTCCAAATGAGGCTATTCGGATAGCAGCAAAACACAAGGGCGGGAT
AGGATTGCTTTTAACGGATGTGGTTATGCCTGAAATGAATGGCTGCGATCTTTCGAACAAGCTCCGCATTACCAGTCCGA
ATCTTAAAACCCTGTTCATGTCGGGATATACAGCTGATATTATATCCCGTCACGGAGTACTCGATGACGGTGGAGATTTT
ATTCAGAAGCCTTTTTCCCTGAAAGCCCTCATGGAAAGCGTGCATAATCTGCTGAAGCCTTCCTCTTCGTAA

Upstream 100 bases:

>100_bases
AATGCATCAAGATTGTTGGATACTATTGTTATGGTCGCATGTTTTCATGTAACTGCGTCGTTGACTATTCGGAAATGTCC
AGTATATAAAACAGAGACTT

Downstream 100 bases:

>100_bases
CTGCTTTTTAGCGCCTTTTTCCTGTCACGGAAAGATAATTCCCGTAAGTATCGCGGTCAACGTTTTCGAGTCTCTCTGTT
GCTTTCTGAGGATGACGGGA

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 823; Mature: 823

Protein sequence:

>823_residues
MHEDNNKREALSGSPVIMNAEQVYAISRQQLQLFMSATHAGIWEWDTVTNSVIWSDEVWALYGLNASCCDATFEAWLSSV
HPEDREKTEKTVLGAARDDVAFEVAWRSRDLDGNERWLMSKGFPLRDGAGRTGRYVGIVLDITDRKQAEDALCESEDRFR
KLFESLSEIKLIIDSHSGKIIDANQAAVDFYGWSIEELTSMNIEQINTTSSELVTLDTEKCGSLHQSCVSFRHRRADGSI
RDVEVFSNNIEIAGNILYYSTIHDVTERKRFEALTAFRLRLLDMAENRSVEELLKATLDESECMTESSFSFCCFLMDERS
SPTLQVLSTSTEKAMSLMNRNQEVFSQLSESSIWSAAILEKKAVIHNDVERDLPEDHPFFKRKLVVPIVQGDTVMAIIGV
GNKQYPYDEDDARWVGTLADVAWDIVARKRAELSEKNTQEALSQSQKMEMVGRLAGGIAHDFNNMLGVILGHTEIALEQL
DPSESAYADLEAIRKAAARSAGLIRQLLAFARKQTVMPKIISLNTMVEGMLTMMRRLIGENITLVWIPENQNAKIKIDPS
QIDQILANLCVNARDSIVGGGRITIETGRLCVQRNENTANHPCRIPGDYVTLAVTDNGSGIDKKHLPHIFEPFFTTKEQG
KGTGLGLSTVYGIVKQNNGCIDCQSEPGKGTCIKIHLPRYIDKADSVPVETPEQSITRGKETILLVEDEPDILKLCKLML
ENNGYTVLSADTPNEAIRIAAKHKGGIGLLLTDVVMPEMNGCDLSNKLRITSPNLKTLFMSGYTADIISRHGVLDDGGDF
IQKPFSLKALMESVHNLLKPSSS

Sequences:

>Translated_823_residues
MHEDNNKREALSGSPVIMNAEQVYAISRQQLQLFMSATHAGIWEWDTVTNSVIWSDEVWALYGLNASCCDATFEAWLSSV
HPEDREKTEKTVLGAARDDVAFEVAWRSRDLDGNERWLMSKGFPLRDGAGRTGRYVGIVLDITDRKQAEDALCESEDRFR
KLFESLSEIKLIIDSHSGKIIDANQAAVDFYGWSIEELTSMNIEQINTTSSELVTLDTEKCGSLHQSCVSFRHRRADGSI
RDVEVFSNNIEIAGNILYYSTIHDVTERKRFEALTAFRLRLLDMAENRSVEELLKATLDESECMTESSFSFCCFLMDERS
SPTLQVLSTSTEKAMSLMNRNQEVFSQLSESSIWSAAILEKKAVIHNDVERDLPEDHPFFKRKLVVPIVQGDTVMAIIGV
GNKQYPYDEDDARWVGTLADVAWDIVARKRAELSEKNTQEALSQSQKMEMVGRLAGGIAHDFNNMLGVILGHTEIALEQL
DPSESAYADLEAIRKAAARSAGLIRQLLAFARKQTVMPKIISLNTMVEGMLTMMRRLIGENITLVWIPENQNAKIKIDPS
QIDQILANLCVNARDSIVGGGRITIETGRLCVQRNENTANHPCRIPGDYVTLAVTDNGSGIDKKHLPHIFEPFFTTKEQG
KGTGLGLSTVYGIVKQNNGCIDCQSEPGKGTCIKIHLPRYIDKADSVPVETPEQSITRGKETILLVEDEPDILKLCKLML
ENNGYTVLSADTPNEAIRIAAKHKGGIGLLLTDVVMPEMNGCDLSNKLRITSPNLKTLFMSGYTADIISRHGVLDDGGDF
IQKPFSLKALMESVHNLLKPSSS
>Mature_823_residues
MHEDNNKREALSGSPVIMNAEQVYAISRQQLQLFMSATHAGIWEWDTVTNSVIWSDEVWALYGLNASCCDATFEAWLSSV
HPEDREKTEKTVLGAARDDVAFEVAWRSRDLDGNERWLMSKGFPLRDGAGRTGRYVGIVLDITDRKQAEDALCESEDRFR
KLFESLSEIKLIIDSHSGKIIDANQAAVDFYGWSIEELTSMNIEQINTTSSELVTLDTEKCGSLHQSCVSFRHRRADGSI
RDVEVFSNNIEIAGNILYYSTIHDVTERKRFEALTAFRLRLLDMAENRSVEELLKATLDESECMTESSFSFCCFLMDERS
SPTLQVLSTSTEKAMSLMNRNQEVFSQLSESSIWSAAILEKKAVIHNDVERDLPEDHPFFKRKLVVPIVQGDTVMAIIGV
GNKQYPYDEDDARWVGTLADVAWDIVARKRAELSEKNTQEALSQSQKMEMVGRLAGGIAHDFNNMLGVILGHTEIALEQL
DPSESAYADLEAIRKAAARSAGLIRQLLAFARKQTVMPKIISLNTMVEGMLTMMRRLIGENITLVWIPENQNAKIKIDPS
QIDQILANLCVNARDSIVGGGRITIETGRLCVQRNENTANHPCRIPGDYVTLAVTDNGSGIDKKHLPHIFEPFFTTKEQG
KGTGLGLSTVYGIVKQNNGCIDCQSEPGKGTCIKIHLPRYIDKADSVPVETPEQSITRGKETILLVEDEPDILKLCKLML
ENNGYTVLSADTPNEAIRIAAKHKGGIGLLLTDVVMPEMNGCDLSNKLRITSPNLKTLFMSGYTADIISRHGVLDDGGDF
IQKPFSLKALMESVHNLLKPSSS

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=29.8449612403101, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1788549, Length=247, Percent_Identity=29.9595141700405, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1788713, Length=220, Percent_Identity=31.3636363636364, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI87081816, Length=265, Percent_Identity=26.7924528301887, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=266, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790300, Length=257, Percent_Identity=29.1828793774319, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87081881, Length=117, Percent_Identity=35.042735042735, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788381, Length=177, Percent_Identity=28.2485875706215, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786600, Length=256, Percent_Identity=25, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI145693157, Length=274, Percent_Identity=23.3576642335766, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 91652; Mature: 91652

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEDNNKREALSGSPVIMNAEQVYAISRQQLQLFMSATHAGIWEWDTVTNSVIWSDEVWA
CCCCCCCHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEECCCEEE
LYGLNASCCDATFEAWLSSVHPEDREKTEKTVLGAARDDVAFEVAWRSRDLDGNERWLMS
EECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEEE
KGFPLRDGAGRTGRYVGIVLDITDRKQAEDALCESEDRFRKLFESLSEIKLIIDSHSGKI
CCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHEEEEEECCCCCE
IDANQAAVDFYGWSIEELTSMNIEQINTTSSELVTLDTEKCGSLHQSCVSFRHRRADGSI
EECCCCEEEECCCCHHHHHCCCHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCC
RDVEVFSNNIEIAGNILYYSTIHDVTERKRFEALTAFRLRLLDMAENRSVEELLKATLDE
EEEEEECCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCH
SECMTESSFSFCCFLMDERSSPTLQVLSTSTEKAMSLMNRNQEVFSQLSESSIWSAAILE
HHHHCCCCCCEEEEEEECCCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KKAVIHNDVERDLPEDHPFFKRKLVVPIVQGDTVMAIIGVGNKQYPYDEDDARWVGTLAD
HHHHHHCCHHHCCCCCCCHHHCEEEEEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHH
VAWDIVARKRAELSEKNTQEALSQSQKMEMVGRLAGGIAHDFNNMLGVILGHTEIALEQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
DPSESAYADLEAIRKAAARSAGLIRQLLAFARKQTVMPKIISLNTMVEGMLTMMRRLIGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCC
NITLVWIPENQNAKIKIDPSQIDQILANLCVNARDSIVGGGRITIETGRLCVQRNENTAN
CEEEEEEECCCCCEEEECHHHHHHHHHHHHCCCCCCEECCCEEEEEECCEEEECCCCCCC
HPCRIPGDYVTLAVTDNGSGIDKKHLPHIFEPFFTTKEQGKGTGLGLSTVYGIVKQNNGC
CCCCCCCCEEEEEEECCCCCCCHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCE
IDCQSEPGKGTCIKIHLPRYIDKADSVPVETPEQSITRGKETILLVEDEPDILKLCKLML
EECCCCCCCCCEEEEECCHHHCCCCCCCCCCCHHHHCCCCCEEEEEECCCCHHHHHHHHH
ENNGYTVLSADTPNEAIRIAAKHKGGIGLLLTDVVMPEMNGCDLSNKLRITSPNLKTLFM
CCCCEEEEECCCCCCEEEEEEECCCCEEEEEHHHHCCCCCCCCCCCEEEEECCCCEEEEE
SGYTADIISRHGVLDDGGDFIQKPFSLKALMESVHNLLKPSSS
CCCHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHEDNNKREALSGSPVIMNAEQVYAISRQQLQLFMSATHAGIWEWDTVTNSVIWSDEVWA
CCCCCCCHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCEEECCCEEE
LYGLNASCCDATFEAWLSSVHPEDREKTEKTVLGAARDDVAFEVAWRSRDLDGNERWLMS
EECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCEEEEE
KGFPLRDGAGRTGRYVGIVLDITDRKQAEDALCESEDRFRKLFESLSEIKLIIDSHSGKI
CCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHCCCHHHHHHHHHHHHHEEEEEECCCCCE
IDANQAAVDFYGWSIEELTSMNIEQINTTSSELVTLDTEKCGSLHQSCVSFRHRRADGSI
EECCCCEEEECCCCHHHHHCCCHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHCCCCCC
RDVEVFSNNIEIAGNILYYSTIHDVTERKRFEALTAFRLRLLDMAENRSVEELLKATLDE
EEEEEECCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCH
SECMTESSFSFCCFLMDERSSPTLQVLSTSTEKAMSLMNRNQEVFSQLSESSIWSAAILE
HHHHCCCCCCEEEEEEECCCCCEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KKAVIHNDVERDLPEDHPFFKRKLVVPIVQGDTVMAIIGVGNKQYPYDEDDARWVGTLAD
HHHHHHCCHHHCCCCCCCHHHCEEEEEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHH
VAWDIVARKRAELSEKNTQEALSQSQKMEMVGRLAGGIAHDFNNMLGVILGHTEIALEQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHC
DPSESAYADLEAIRKAAARSAGLIRQLLAFARKQTVMPKIISLNTMVEGMLTMMRRLIGE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCC
NITLVWIPENQNAKIKIDPSQIDQILANLCVNARDSIVGGGRITIETGRLCVQRNENTAN
CEEEEEEECCCCCEEEECHHHHHHHHHHHHCCCCCCEECCCEEEEEECCEEEECCCCCCC
HPCRIPGDYVTLAVTDNGSGIDKKHLPHIFEPFFTTKEQGKGTGLGLSTVYGIVKQNNGC
CCCCCCCCEEEEEEECCCCCCCHHCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCE
IDCQSEPGKGTCIKIHLPRYIDKADSVPVETPEQSITRGKETILLVEDEPDILKLCKLML
EECCCCCCCCCEEEEECCHHHCCCCCCCCCCCHHHHCCCCCEEEEEECCCCHHHHHHHHH
ENNGYTVLSADTPNEAIRIAAKHKGGIGLLLTDVVMPEMNGCDLSNKLRITSPNLKTLFM
CCCCEEEEECCCCCCEEEEEEECCCCEEEEEHHHHCCCCCCCCCCCEEEEECCCCEEEEE
SGYTADIISRHGVLDDGGDFIQKPFSLKALMESVHNLLKPSSS
CCCHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA