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The map label for this gene is coaE [H]

Identifier: 119356812

GI number: 119356812

Start: 1125162

End: 1125797

Strand: Direct

Name: coaE [H]

Synonym: Cpha266_0985

Alternate gene names: 119356812

Gene position: 1125162-1125797 (Clockwise)

Preceding gene: 119356811

Following gene: 119356815

Centisome position: 35.9

GC content: 48.9

Gene sequence:

>636_bases
ATGGTTGTAAATCCGTTTCTTGTAGGTGTAACGGGTGGCATAGGCAGCGGAAAATCAACGCTGTGCCGTTATCTCGCTGA
ACTGGGATGTGAGCTTTTTGAGGCCGATGTTGTGGCAAAGGAGTTGCAGCTTGACGATAGCGAGGTTATCAGCGGCATTA
AAAAGCTTTTTGGCGAAAATGTCTATGGCAAAGATCCTGAAGGGAATCTTTTTCTTGATCGGCGAATGATTGCCGGTGTC
GTGTTTTCTGATCGAGAAAAGCTTGATGCCCTTAACAGGCTTGTGCATCCCAAGGTATTTAATGCATTCGACCGGGCTCT
TGAACGTGCCCGATCGAACGGCTCTCGTCTGCTTGTCAAGGAGGCTGCAATTCTGTTTGAGTCAGGTTCTTCAACCGCGC
TTGATTTTGTCGTTGTTGTCGCATCCGGTATGGAAGAGAGAGTTGCACGAGCTGTGGCAAAAGGTCTTGGAAGCCGTGAA
GAGATTTTTCGGAGGATCGGCTCGCAGTGGCCACAGGAAAAACTTATGGAGATGGCAGATTATGTCGTCTGCAATAACGG
TTCGCTTGAAGAGCTTCGCCTCAAGGCCGTCGCCTTGTATCGGTATCTGCTTTCTCTGGCAGAGAGAGATTCATAG

Upstream 100 bases:

>100_bases
TGAACGGACGAATCAGATTTTATAAAGAACATCCCTTGCGATGGCGCAGCGTTCTTCTGGAAGTACGTGAAAATATTCGT
AAAAAACGGTTGTGAGAAGT

Downstream 100 bases:

>100_bases
GGCAATAGCCGCACTGAGCAGGGGGAGCGAGGTGTCGTAACGGTAGGAGGTATCGCTGTGAGAGTCCGGAAATTCTTCGT
AATGGTGAGCAATACCGTAA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MVVNPFLVGVTGGIGSGKSTLCRYLAELGCELFEADVVAKELQLDDSEVISGIKKLFGENVYGKDPEGNLFLDRRMIAGV
VFSDREKLDALNRLVHPKVFNAFDRALERARSNGSRLLVKEAAILFESGSSTALDFVVVVASGMEERVARAVAKGLGSRE
EIFRRIGSQWPQEKLMEMADYVVCNNGSLEELRLKAVALYRYLLSLAERDS

Sequences:

>Translated_211_residues
MVVNPFLVGVTGGIGSGKSTLCRYLAELGCELFEADVVAKELQLDDSEVISGIKKLFGENVYGKDPEGNLFLDRRMIAGV
VFSDREKLDALNRLVHPKVFNAFDRALERARSNGSRLLVKEAAILFESGSSTALDFVVVVASGMEERVARAVAKGLGSRE
EIFRRIGSQWPQEKLMEMADYVVCNNGSLEELRLKAVALYRYLLSLAERDS
>Mature_211_residues
MVVNPFLVGVTGGIGSGKSTLCRYLAELGCELFEADVVAKELQLDDSEVISGIKKLFGENVYGKDPEGNLFLDRRMIAGV
VFSDREKLDALNRLVHPKVFNAFDRALERARSNGSRLLVKEAAILFESGSSTALDFVVVVASGMEERVARAVAKGLGSRE
EIFRRIGSQWPQEKLMEMADYVVCNNGSLEELRLKAVALYRYLLSLAERDS

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=196, Percent_Identity=25.5102040816327, Blast_Score=77, Evalue=8e-15,
Organism=Homo sapiens, GI191252795, Length=196, Percent_Identity=25.5102040816327, Blast_Score=77, Evalue=8e-15,
Organism=Escherichia coli, GI1786292, Length=204, Percent_Identity=27.4509803921569, Blast_Score=83, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17554944, Length=190, Percent_Identity=30, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI25143409, Length=188, Percent_Identity=29.7872340425532, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320402, Length=195, Percent_Identity=29.7435897435897, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24644728, Length=201, Percent_Identity=29.3532338308458, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI24658602, Length=201, Percent_Identity=27.363184079602, Blast_Score=84, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 23296; Mature: 23296

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVNPFLVGVTGGIGSGKSTLCRYLAELGCELFEADVVAKELQLDDSEVISGIKKLFGEN
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
VYGKDPEGNLFLDRRMIAGVVFSDREKLDALNRLVHPKVFNAFDRALERARSNGSRLLVK
CCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEHHH
EAAILFESGSSTALDFVVVVASGMEERVARAVAKGLGSREEIFRRIGSQWPQEKLMEMAD
HHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH
YVVCNNGSLEELRLKAVALYRYLLSLAERDS
HHEECCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVVNPFLVGVTGGIGSGKSTLCRYLAELGCELFEADVVAKELQLDDSEVISGIKKLFGEN
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
VYGKDPEGNLFLDRRMIAGVVFSDREKLDALNRLVHPKVFNAFDRALERARSNGSRLLVK
CCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEHHH
EAAILFESGSSTALDFVVVVASGMEERVARAVAKGLGSREEIFRRIGSQWPQEKLMEMAD
HHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHH
YVVCNNGSLEELRLKAVALYRYLLSLAERDS
HHEECCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA