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The map label for this gene is nuoL [H]

Identifier: 119356797

GI number: 119356797

Start: 1108387

End: 1110666

Strand: Direct

Name: nuoL [H]

Synonym: Cpha266_0969

Alternate gene names: 119356797

Gene position: 1108387-1110666 (Clockwise)

Preceding gene: 119356796

Following gene: 119356798

Centisome position: 35.37

GC content: 47.63

Gene sequence:

>2280_bases
ATGCACAGTTTAATTCAGTTATCAATAGTCGTACTGCTGCTGCCATTGCTCTCGTTTGTCATTCTCATTTTTTTTAACCG
GCGTCTTCCGGGAAGAGGGGATTTCATCGGGGTAGGGATTCTCGGCGCAGCGTTTGCTCTATCCGCATATATCTTTTGGT
CTGTTATTGTACAGGCGTATGATCCGCTTTTTAAAATAGCATGGAGCTTTACCTGGATTGATCTCGGGATGGTTCCGGGA
GTAGGTCCGCTGAAAATCAACATGGGTATTGTTATTGATAACCTGACGGCTATCATGCTTACAATGGTGACGCTTATCAG
TTTGCTTGTTCATATCTATTCGACAGGTTATATGGCAGGCGACAAGCACTACGGCCGATATTTTGCCTATCTCGGTATCT
TTACTTTTTCGATGCTTGGTATTGTTCTGTCCGACAATCTGTTTTCGATCTATATGTTCTGGGAGCTGGTCGGTCTTTCT
TCCTACCTCCTGATCGGCTTTTTCTTTGAAAAAGACAGCGCTGCTGATGCCCAGAAAAAAGCTTTTCTTGCCAACCGTGT
TGGTGATATAGGAATGTGGCTCGGTATTCTTATTCTCTATTCCCAGTTTCACACCTTCAATTACGACGATATTTTCGGGG
CTCTTGCTGCGGGGAAGTTCACGCTCTCTCAAGGATGGTTGACCGCGGCAGGTATTCTTCTCTTCATGGGCTGTGTCGGT
AAATCGGCGCAGTTTCCTCTTCATGTATGGCTTCCCGATGCAATGGAAGGTCCTACCCCGGTATCCGCACTTATTCACGC
TGCAACCATGGTCGCAGCCGGCGTTTACTTTGTCGCTCGTATTTTTGTGCTTTTGACCCCTGATGCCCTGCATGTCATCT
CGTTTATTGGAGCGTTTACAGCATTTATGGCAGCCACGATTGCCATTACCCAGAACGATATTAAAAGAGTGCTGGCCTAC
TCAACGGTTTCCCAGCTTGGCTATATGGTGCTTGGCCTTGGAGTCGGAGCTTACTCCGCAGCTTTGTTTCATCTTGTTAC
GCATGCGTTTTTCAAGGCATGTCTTTTTCTTGGATCCGGTGCAATTATTCACGCCATGCATCATGAGCAGGATATGCGCT
GGATGGGCGGTCTGCGCAAACCGATGCCATGGACCTTCGTTACCTTTACGATTGCAACCCTTGCTCTTGCCGGCCTTCCA
CTGACAAGTGGTTTTATGAGCAAAGACGCCATTCTTGCCGGTGCCATAGGCTTTGCTGAAGCTGAGGGCGGCGGGATCTA
CTATCTGATTCCGGTTCTCGGCTTTTTTTCAGCCATGCTGACGGCTTTTTATATGGGACGCCAAATCTGGCTGGTCTTTT
TTGGAGATAGCCGTACCCATCTGAAACCTGCCGAACATCATGCTCACGGTCATGACGCTCATCATGGTCACGATGATGAA
CACGGCGGGGATCATGGTGTTCATGAAGTATCCTGGAATATGAGGGCTCCTCTTGTCGTTCTTGCCGCGCTTTCAGTTTT
TGCTGTTTACTCTCCGGATCCACTTGATGGAGCCAAAGGCTGGTTCATGAGCATGGTTCAGACTCCCGAGACAGTTGTGG
GCGACAAGCCGCCGGTTGAGCATACCGTCCTGACTGAGGGTAACAGTGGGAATCTGCTCCTTGCAGAATCTGTTGATCAC
ACAGAGCTGCCTCATGGTACCGATGTTTCTCACATGCCTGTTGCGGCAACTCACGGTGCTACGGAGGGCGATCATCACAC
CGGTCACACGTTTGCTGATCCAAGACAGGCAGCTATTGCTCATGGCGCACATGAAGCTCACAATCCGGCTATCATCATAT
CAAGCATTATGGTCGCGCTTGGAATCAGTATGGCCGGCATTGTTTATGTCTTCAAGGTTATCGATCCCGACAGTACCGCC
CGGAATATCCGTCCCCTTTATCTCTTTTCATTGAACAAGTGGTACTGGGACGAAATATATGATGCGACCGTCATCAAAGG
CTCAATACTGATTTCGAAAATATTTGCCTGGTTTGACAGCAACATCATTGACGGCCTTGTTAACGGTATTGCCGTGACCG
TCAGAAAATTCGCATTTGCAAATGGTAGCTTTGACAAATATGTTGTTGACGGACTTGTGAATTTTACCGCATTTTTTGTC
AATACCAGTGGTGCACTGCTCAGAAAATTTCAGACCGGAAAGGTGCAGACCTATGTAGTACTCCTTATGATTGCTGTTTG
CGGCTATTTTGTCTATTACTTTACACAACTGGTCTATTAA

Upstream 100 bases:

>100_bases
ATATTCAAAAGCGTTGATGTGTCGAGCATCGACACCATGAAAGAGTAACACCCCGGATAAAGGGTATCAGTTTTAATTTT
TTCTTGTAAACCGAAAGAAC

Downstream 100 bases:

>100_bases
GAGATTTACTTTTAATCTGAAAACCTACAGATACGGAACATGCTGAGTTTAATCGTCTTTTTGCCTATTCTTGCCGGTCT
TGTGATTCTTGCCGTGCCTT

Product: proton-translocating NADH-quinone oxidoreductase, chain L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 759; Mature: 759

Protein sequence:

>759_residues
MHSLIQLSIVVLLLPLLSFVILIFFNRRLPGRGDFIGVGILGAAFALSAYIFWSVIVQAYDPLFKIAWSFTWIDLGMVPG
VGPLKINMGIVIDNLTAIMLTMVTLISLLVHIYSTGYMAGDKHYGRYFAYLGIFTFSMLGIVLSDNLFSIYMFWELVGLS
SYLLIGFFFEKDSAADAQKKAFLANRVGDIGMWLGILILYSQFHTFNYDDIFGALAAGKFTLSQGWLTAAGILLFMGCVG
KSAQFPLHVWLPDAMEGPTPVSALIHAATMVAAGVYFVARIFVLLTPDALHVISFIGAFTAFMAATIAITQNDIKRVLAY
STVSQLGYMVLGLGVGAYSAALFHLVTHAFFKACLFLGSGAIIHAMHHEQDMRWMGGLRKPMPWTFVTFTIATLALAGLP
LTSGFMSKDAILAGAIGFAEAEGGGIYYLIPVLGFFSAMLTAFYMGRQIWLVFFGDSRTHLKPAEHHAHGHDAHHGHDDE
HGGDHGVHEVSWNMRAPLVVLAALSVFAVYSPDPLDGAKGWFMSMVQTPETVVGDKPPVEHTVLTEGNSGNLLLAESVDH
TELPHGTDVSHMPVAATHGATEGDHHTGHTFADPRQAAIAHGAHEAHNPAIIISSIMVALGISMAGIVYVFKVIDPDSTA
RNIRPLYLFSLNKWYWDEIYDATVIKGSILISKIFAWFDSNIIDGLVNGIAVTVRKFAFANGSFDKYVVDGLVNFTAFFV
NTSGALLRKFQTGKVQTYVVLLMIAVCGYFVYYFTQLVY

Sequences:

>Translated_759_residues
MHSLIQLSIVVLLLPLLSFVILIFFNRRLPGRGDFIGVGILGAAFALSAYIFWSVIVQAYDPLFKIAWSFTWIDLGMVPG
VGPLKINMGIVIDNLTAIMLTMVTLISLLVHIYSTGYMAGDKHYGRYFAYLGIFTFSMLGIVLSDNLFSIYMFWELVGLS
SYLLIGFFFEKDSAADAQKKAFLANRVGDIGMWLGILILYSQFHTFNYDDIFGALAAGKFTLSQGWLTAAGILLFMGCVG
KSAQFPLHVWLPDAMEGPTPVSALIHAATMVAAGVYFVARIFVLLTPDALHVISFIGAFTAFMAATIAITQNDIKRVLAY
STVSQLGYMVLGLGVGAYSAALFHLVTHAFFKACLFLGSGAIIHAMHHEQDMRWMGGLRKPMPWTFVTFTIATLALAGLP
LTSGFMSKDAILAGAIGFAEAEGGGIYYLIPVLGFFSAMLTAFYMGRQIWLVFFGDSRTHLKPAEHHAHGHDAHHGHDDE
HGGDHGVHEVSWNMRAPLVVLAALSVFAVYSPDPLDGAKGWFMSMVQTPETVVGDKPPVEHTVLTEGNSGNLLLAESVDH
TELPHGTDVSHMPVAATHGATEGDHHTGHTFADPRQAAIAHGAHEAHNPAIIISSIMVALGISMAGIVYVFKVIDPDSTA
RNIRPLYLFSLNKWYWDEIYDATVIKGSILISKIFAWFDSNIIDGLVNGIAVTVRKFAFANGSFDKYVVDGLVNFTAFFV
NTSGALLRKFQTGKVQTYVVLLMIAVCGYFVYYFTQLVY
>Mature_759_residues
MHSLIQLSIVVLLLPLLSFVILIFFNRRLPGRGDFIGVGILGAAFALSAYIFWSVIVQAYDPLFKIAWSFTWIDLGMVPG
VGPLKINMGIVIDNLTAIMLTMVTLISLLVHIYSTGYMAGDKHYGRYFAYLGIFTFSMLGIVLSDNLFSIYMFWELVGLS
SYLLIGFFFEKDSAADAQKKAFLANRVGDIGMWLGILILYSQFHTFNYDDIFGALAAGKFTLSQGWLTAAGILLFMGCVG
KSAQFPLHVWLPDAMEGPTPVSALIHAATMVAAGVYFVARIFVLLTPDALHVISFIGAFTAFMAATIAITQNDIKRVLAY
STVSQLGYMVLGLGVGAYSAALFHLVTHAFFKACLFLGSGAIIHAMHHEQDMRWMGGLRKPMPWTFVTFTIATLALAGLP
LTSGFMSKDAILAGAIGFAEAEGGGIYYLIPVLGFFSAMLTAFYMGRQIWLVFFGDSRTHLKPAEHHAHGHDAHHGHDDE
HGGDHGVHEVSWNMRAPLVVLAALSVFAVYSPDPLDGAKGWFMSMVQTPETVVGDKPPVEHTVLTEGNSGNLLLAESVDH
TELPHGTDVSHMPVAATHGATEGDHHTGHTFADPRQAAIAHGAHEAHNPAIIISSIMVALGISMAGIVYVFKVIDPDSTA
RNIRPLYLFSLNKWYWDEIYDATVIKGSILISKIFAWFDSNIIDGLVNGIAVTVRKFAFANGSFDKYVVDGLVNFTAFFV
NTSGALLRKFQTGKVQTYVVLLMIAVCGYFVYYFTQLVY

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=377, Percent_Identity=38.4615384615385, Blast_Score=239, Evalue=7e-63,
Organism=Escherichia coli, GI1788614, Length=543, Percent_Identity=41.9889502762431, Blast_Score=350, Evalue=2e-97,
Organism=Escherichia coli, GI1788829, Length=431, Percent_Identity=34.1067285382831, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI1788827, Length=347, Percent_Identity=31.1239193083574, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI1788831, Length=339, Percent_Identity=30.0884955752212, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI1788613, Length=414, Percent_Identity=25.6038647342995, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI145693160, Length=358, Percent_Identity=26.536312849162, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI2367154, Length=188, Percent_Identity=29.2553191489362, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR002128
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF01010 Oxidored_q1_C; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 82993; Mature: 82993

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSLIQLSIVVLLLPLLSFVILIFFNRRLPGRGDFIGVGILGAAFALSAYIFWSVIVQAY
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
DPLFKIAWSFTWIDLGMVPGVGPLKINMGIVIDNLTAIMLTMVTLISLLVHIYSTGYMAG
HHHHHHHHHHHEEEECCCCCCCCEEEEECEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DKHYGRYFAYLGIFTFSMLGIVLSDNLFSIYMFWELVGLSSYLLIGFFFEKDSAADAQKK
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHH
AFLANRVGDIGMWLGILILYSQFHTFNYDDIFGALAAGKFTLSQGWLTAAGILLFMGCVG
HHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHCC
KSAQFPLHVWLPDAMEGPTPVSALIHAATMVAAGVYFVARIFVLLTPDALHVISFIGAFT
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AFMAATIAITQNDIKRVLAYSTVSQLGYMVLGLGVGAYSAALFHLVTHAFFKACLFLGSG
HHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCC
AIIHAMHHEQDMRWMGGLRKPMPWTFVTFTIATLALAGLPLTSGFMSKDAILAGAIGFAE
CEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCEE
AEGGGIYYLIPVLGFFSAMLTAFYMGRQIWLVFFGDSRTHLKPAEHHAHGHDAHHGHDDE
CCCCCEEEHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCC
HGGDHGVHEVSWNMRAPLVVLAALSVFAVYSPDPLDGAKGWFMSMVQTPETVVGDKPPVE
CCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHCCCCCCCC
HTVLTEGNSGNLLLAESVDHTELPHGTDVSHMPVAATHGATEGDHHTGHTFADPRQAAIA
CEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHH
HGAHEAHNPAIIISSIMVALGISMAGIVYVFKVIDPDSTARNIRPLYLFSLNKWYWDEIY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEEECCCHHHHHHH
DATVIKGSILISKIFAWFDSNIIDGLVNGIAVTVRKFAFANGSFDKYVVDGLVNFTAFFV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEE
NTSGALLRKFQTGKVQTYVVLLMIAVCGYFVYYFTQLVY
ECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHSLIQLSIVVLLLPLLSFVILIFFNRRLPGRGDFIGVGILGAAFALSAYIFWSVIVQAY
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHH
DPLFKIAWSFTWIDLGMVPGVGPLKINMGIVIDNLTAIMLTMVTLISLLVHIYSTGYMAG
HHHHHHHHHHHEEEECCCCCCCCEEEEECEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DKHYGRYFAYLGIFTFSMLGIVLSDNLFSIYMFWELVGLSSYLLIGFFFEKDSAADAQKK
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHH
AFLANRVGDIGMWLGILILYSQFHTFNYDDIFGALAAGKFTLSQGWLTAAGILLFMGCVG
HHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHCC
KSAQFPLHVWLPDAMEGPTPVSALIHAATMVAAGVYFVARIFVLLTPDALHVISFIGAFT
CCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AFMAATIAITQNDIKRVLAYSTVSQLGYMVLGLGVGAYSAALFHLVTHAFFKACLFLGSG
HHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCC
AIIHAMHHEQDMRWMGGLRKPMPWTFVTFTIATLALAGLPLTSGFMSKDAILAGAIGFAE
CEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCEE
AEGGGIYYLIPVLGFFSAMLTAFYMGRQIWLVFFGDSRTHLKPAEHHAHGHDAHHGHDDE
CCCCCEEEHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHCCCCCCCCCCCCCC
HGGDHGVHEVSWNMRAPLVVLAALSVFAVYSPDPLDGAKGWFMSMVQTPETVVGDKPPVE
CCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHCCCCCCCC
HTVLTEGNSGNLLLAESVDHTELPHGTDVSHMPVAATHGATEGDHHTGHTFADPRQAAIA
CEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHH
HGAHEAHNPAIIISSIMVALGISMAGIVYVFKVIDPDSTARNIRPLYLFSLNKWYWDEIY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCEEEEEECCCHHHHHHH
DATVIKGSILISKIFAWFDSNIIDGLVNGIAVTVRKFAFANGSFDKYVVDGLVNFTAFFV
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEE
NTSGALLRKFQTGKVQTYVVLLMIAVCGYFVYYFTQLVY
ECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]