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The map label for this gene is eriC [C]

Identifier: 118581673

GI number: 118581673

Start: 3606446

End: 3607891

Strand: Direct

Name: eriC [C]

Synonym: Ppro_3273

Alternate gene names: 118581673

Gene position: 3606446-3607891 (Clockwise)

Preceding gene: 118581660

Following gene: 118581677

Centisome position: 89.98

GC content: 64.45

Gene sequence:

>1446_bases
GTGCGGCCAAACATATCCGAACAGTTCACCCTCCTCGCCAGCGTCGTCAAGTGGACCTGCTATGCCTCGATCGTCGGCAT
CCTGTCAGGATGCGGCACAACCCTGTTTCTCTGGGCACTGGCCCAGGCGACCCGGCTGTTTGCCCTGATCCCCGACTACT
ATCTGCTGCTCCCCGTTACCCTGGTCGTCTGCAGCCTGTTCGTCACCCGCTTTTCGCCGGCCAGCGTCTGTCGGGGAACC
GACGCTATCATCGAGGCGGTCCACCAGAACATGGGGAGGATGCCGCTTCTCTCCCTGCCGATCAAGCTGATCGCCACGGT
GGTCACCATCGCCGGCGGCGGGTCGGCAGGGAAGGAGTGCCCCAGCGCCCAGATCGGCGCCGGCCTGGCCTCGGCCTTCG
GCCGCCTCATGAGGCTGGATGACGTTGACCAGCGCAAGCTGGTCATCTGCGGTATCAGTGCCGGTTTCGCCACCGTATTC
GGCACCCCCATCGCCGGCGCCCTCTTCGGCGTGGAGGTGCTGGTGCTGGGCCAGATGATGTACGATGTGCTCTTTCCCTC
CTTTGTCGCCGGGATCATCGGTTTTCACGTGGCTTCCCAGCTGGGGGTTGAGTACCCCCACCTGGTGGCCAGCGCCATCC
CCCGGCTCACCGGCTGGAGTTTCGCGGAGATGCTTCTGCTGGGAGTCTGGTGCGGCCTGATCGCCCTGCTGTTCATCGAA
ATGATGAAGTTGAGCAAGCGCCTGTTCAACCCGTGCGCCGGGAACGCGATCCCCAAGGCGCTCCTGGGGGGGACGTTATT
GGCTCTGATCGGCAAGTTCCTCTCCACCAGCTACCTGGGGCTGGGGATCGACACCATCGAGGCGGGGCTTAAGGGGACGG
TGCTTCCGGTGGAAGCCTGGCTGGTGAAGAGCGTTGCCACCGCCATCACCCTCGGCAGCGGCGGCAGCGGCGGGGTGGTC
ACGCCGATCATGTTCATCGGCGCCTCGGCCGGCAACCTGTTCGCCTCGCTGTTCAACGAGCCGCAGATCGCGACCTTCTC
TATCATCGGCATGGCCGCGGTTCTGGCGGGGGCGGCAAACACTCCCATCGCCGCATCGGTGATGGCCATGGAGCTGTTCG
GCGCCGGAATCGCGCCCAATGCCGCCGTGGCCTGCATGGTCAGTTTCCTGATCGTCGGCTACCGCAGCATCTACTCCAGC
CAGGTCCTGGGTATCCAGAAGAGTACGTCACTCAAGGTGGAGACGGGGAAACCGCTGTCGCAGTTCCGGAGAGCCCGGGT
CAACCACCGGGAGAAGTCCCTCGTGGGGCTGATCGAGCGGGGGACGCACCGGTTGCGGGATATCTCACGCCATGAGCGGC
GCACCCCGCACAAAGAGGGGCGCACATCGATTGAGAGCGAAGGGACCGGCAAAGACACCGGTGTGAAGCAGGACAGCGGG
GAATAA

Upstream 100 bases:

>100_bases
AACAAACGGCGGCCGACAACAAAGCCCTGCCTATCTCCACCCTCCAGCGCGAACAACCGGCCCTTTCCCCGCCGGTTGTT
CGCGTTCCCAAGGATCTCCC

Downstream 100 bases:

>100_bases
GGCGGTGGACGAAAGAGGGGGGCAGGAGTAGCAAGTTCAGGTTTCAGGCGTGAAAGCATCTGTTTCCGGGGATTCAGCTC
ATACGTCGGGGACGACCGAG

Product: Cl- channel, voltage-gated family protein

Products: Cl Ion [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MRPNISEQFTLLASVVKWTCYASIVGILSGCGTTLFLWALAQATRLFALIPDYYLLLPVTLVVCSLFVTRFSPASVCRGT
DAIIEAVHQNMGRMPLLSLPIKLIATVVTIAGGGSAGKECPSAQIGAGLASAFGRLMRLDDVDQRKLVICGISAGFATVF
GTPIAGALFGVEVLVLGQMMYDVLFPSFVAGIIGFHVASQLGVEYPHLVASAIPRLTGWSFAEMLLLGVWCGLIALLFIE
MMKLSKRLFNPCAGNAIPKALLGGTLLALIGKFLSTSYLGLGIDTIEAGLKGTVLPVEAWLVKSVATAITLGSGGSGGVV
TPIMFIGASAGNLFASLFNEPQIATFSIIGMAAVLAGAANTPIAASVMAMELFGAGIAPNAAVACMVSFLIVGYRSIYSS
QVLGIQKSTSLKVETGKPLSQFRRARVNHREKSLVGLIERGTHRLRDISRHERRTPHKEGRTSIESEGTGKDTGVKQDSG
E

Sequences:

>Translated_481_residues
MRPNISEQFTLLASVVKWTCYASIVGILSGCGTTLFLWALAQATRLFALIPDYYLLLPVTLVVCSLFVTRFSPASVCRGT
DAIIEAVHQNMGRMPLLSLPIKLIATVVTIAGGGSAGKECPSAQIGAGLASAFGRLMRLDDVDQRKLVICGISAGFATVF
GTPIAGALFGVEVLVLGQMMYDVLFPSFVAGIIGFHVASQLGVEYPHLVASAIPRLTGWSFAEMLLLGVWCGLIALLFIE
MMKLSKRLFNPCAGNAIPKALLGGTLLALIGKFLSTSYLGLGIDTIEAGLKGTVLPVEAWLVKSVATAITLGSGGSGGVV
TPIMFIGASAGNLFASLFNEPQIATFSIIGMAAVLAGAANTPIAASVMAMELFGAGIAPNAAVACMVSFLIVGYRSIYSS
QVLGIQKSTSLKVETGKPLSQFRRARVNHREKSLVGLIERGTHRLRDISRHERRTPHKEGRTSIESEGTGKDTGVKQDSG
E
>Mature_481_residues
MRPNISEQFTLLASVVKWTCYASIVGILSGCGTTLFLWALAQATRLFALIPDYYLLLPVTLVVCSLFVTRFSPASVCRGT
DAIIEAVHQNMGRMPLLSLPIKLIATVVTIAGGGSAGKECPSAQIGAGLASAFGRLMRLDDVDQRKLVICGISAGFATVF
GTPIAGALFGVEVLVLGQMMYDVLFPSFVAGIIGFHVASQLGVEYPHLVASAIPRLTGWSFAEMLLLGVWCGLIALLFIE
MMKLSKRLFNPCAGNAIPKALLGGTLLALIGKFLSTSYLGLGIDTIEAGLKGTVLPVEAWLVKSVATAITLGSGGSGGVV
TPIMFIGASAGNLFASLFNEPQIATFSIIGMAAVLAGAANTPIAASVMAMELFGAGIAPNAAVACMVSFLIVGYRSIYSS
QVLGIQKSTSLKVETGKPLSQFRRARVNHREKSLVGLIERGTHRLRDISRHERRTPHKEGRTSIESEGTGKDTGVKQDSG
E

Specific function: Selective chloride channel [C]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family [H]

Homologues:

Organism=Escherichia coli, GI1786350, Length=383, Percent_Identity=27.154046997389, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 50668; Mature: 50668

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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C
>Mature Secondary Structure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C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cl Ion [Periplasm] [C]

Specific reaction: Cl Ion [Periplasm] = Cl Ion [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]