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The map label for this gene is yhcK [H]

Identifier: 118578981

GI number: 118578981

Start: 578891

End: 579748

Strand: Direct

Name: yhcK [H]

Synonym: Ppro_0542

Alternate gene names: 118578981

Gene position: 578891-579748 (Clockwise)

Preceding gene: 118578980

Following gene: 118578982

Centisome position: 14.44

GC content: 48.14

Gene sequence:

>858_bases
TTGAGACAGTCTCTTCATGAAATAAACAGGAAAATCGAACTGCTGCCGGCATGGCTGTTAACCGGTCTGACGCTCATCGG
TCTCGGGATCATTGGTTTTTTTGACTATTTTACTGGTCCTGATTACTCTTTTTCCATTTTTTATCTGGTCATTGTCGTTG
CAAGCGCTTGGTATCAGGGGCGGAAATCGGCACTTCTGCTGTCAGGTGCGGGCACCGTTGTCTGGTTTGCCGCAGCTATC
GCCTCTCGGGAATATACCGATGACTATCCGCTGTCTATCTTCTGGAACGATCTGGTAGAACTGACCCATTTTCTTTTTGC
CGTTGTTGTGATTTCCACTTTGAAAGCTTTACTTGATGCCTCGGAAAAGACATCCAGAATAGATCCGTTGACCGGTATAG
CAAACCGGCGCCTTTTCTATGAGGTGGCCACTACAGAGATAGTCAGGGCTCACCGGATATCTGAACCATTCACGGTTATG
TATATTGATATTGACAACTTTAAAACCGTTAACGATACCCAGGGGCATGATGAAGGAGATATACTTCTGATTGCGGTTGC
CTCAACCATCAGGCATCAGATACGGGAAATCGATACTGTGGCACGACTGGGTGGCGATGAATTCAGCGTGCTGCTTCCCG
CAGCCGCAAACGATGCCGCTCAGGTTGTTGGCAGAAAGCTGAAACGTGAACTTGCGGATGCTGTTGAGACAAGGTGGCCG
GTTACCTTCAGTATCGGAATGGTTACCTACATCACAGCGCCTGAATCGGTTGAATACATGATCCGGCAGGCTGACCAGGT
CATGTACGAAGCTAAAAAGTCAGGGAAGAACCGGTTGTGTAGCGTTGTCATGCATTGA

Upstream 100 bases:

>100_bases
GTAGCCGGGTGGCTCATATCTGCGTCAAAGACAGACTGAAGGTTCTATTACAACTGATTGCAGAAAAGGTATGACAGTGC
AGTAAAAGAGGATTAACCGC

Downstream 100 bases:

>100_bases
GATAACGGAGCGGTGCAGACTGCCGATAATGTGAATCCGAGAGGGAGTTGCCGATGAAGAGACATCCGATAACCAGAGAG
AGCGGCAGATACTTCCTGAC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MRQSLHEINRKIELLPAWLLTGLTLIGLGIIGFFDYFTGPDYSFSIFYLVIVVASAWYQGRKSALLLSGAGTVVWFAAAI
ASREYTDDYPLSIFWNDLVELTHFLFAVVVISTLKALLDASEKTSRIDPLTGIANRRLFYEVATTEIVRAHRISEPFTVM
YIDIDNFKTVNDTQGHDEGDILLIAVASTIRHQIREIDTVARLGGDEFSVLLPAAANDAAQVVGRKLKRELADAVETRWP
VTFSIGMVTYITAPESVEYMIRQADQVMYEAKKSGKNRLCSVVMH

Sequences:

>Translated_285_residues
MRQSLHEINRKIELLPAWLLTGLTLIGLGIIGFFDYFTGPDYSFSIFYLVIVVASAWYQGRKSALLLSGAGTVVWFAAAI
ASREYTDDYPLSIFWNDLVELTHFLFAVVVISTLKALLDASEKTSRIDPLTGIANRRLFYEVATTEIVRAHRISEPFTVM
YIDIDNFKTVNDTQGHDEGDILLIAVASTIRHQIREIDTVARLGGDEFSVLLPAAANDAAQVVGRKLKRELADAVETRWP
VTFSIGMVTYITAPESVEYMIRQADQVMYEAKKSGKNRLCSVVMH
>Mature_285_residues
MRQSLHEINRKIELLPAWLLTGLTLIGLGIIGFFDYFTGPDYSFSIFYLVIVVASAWYQGRKSALLLSGAGTVVWFAAAI
ASREYTDDYPLSIFWNDLVELTHFLFAVVVISTLKALLDASEKTSRIDPLTGIANRRLFYEVATTEIVRAHRISEPFTVM
YIDIDNFKTVNDTQGHDEGDILLIAVASTIRHQIREIDTVARLGGDEFSVLLPAAANDAAQVVGRKLKRELADAVETRWP
VTFSIGMVTYITAPESVEYMIRQADQVMYEAKKSGKNRLCSVVMH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=178, Percent_Identity=34.8314606741573, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI87081881, Length=191, Percent_Identity=32.4607329842932, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI145693134, Length=179, Percent_Identity=34.6368715083799, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788085, Length=207, Percent_Identity=29.951690821256, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786584, Length=181, Percent_Identity=30.939226519337, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082007, Length=163, Percent_Identity=34.9693251533742, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787816, Length=160, Percent_Identity=33.75, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787802, Length=180, Percent_Identity=28.3333333333333, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788381, Length=157, Percent_Identity=31.2101910828025, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787541, Length=164, Percent_Identity=32.9268292682927, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081977, Length=155, Percent_Identity=31.6129032258064, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081974, Length=189, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788956, Length=170, Percent_Identity=32.3529411764706, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 31918; Mature: 31918

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQSLHEINRKIELLPAWLLTGLTLIGLGIIGFFDYFTGPDYSFSIFYLVIVVASAWYQG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
RKSALLLSGAGTVVWFAAAIASREYTDDYPLSIFWNDLVELTHFLFAVVVISTLKALLDA
CCCEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SEKTSRIDPLTGIANRRLFYEVATTEIVRAHRISEPFTVMYIDIDNFKTVNDTQGHDEGD
CHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEECCCCCCCCCCC
ILLIAVASTIRHQIREIDTVARLGGDEFSVLLPAAANDAAQVVGRKLKRELADAVETRWP
EEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
VTFSIGMVTYITAPESVEYMIRQADQVMYEAKKSGKNRLCSVVMH
EEEEECEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MRQSLHEINRKIELLPAWLLTGLTLIGLGIIGFFDYFTGPDYSFSIFYLVIVVASAWYQG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
RKSALLLSGAGTVVWFAAAIASREYTDDYPLSIFWNDLVELTHFLFAVVVISTLKALLDA
CCCEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SEKTSRIDPLTGIANRRLFYEVATTEIVRAHRISEPFTVMYIDIDNFKTVNDTQGHDEGD
CHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEECCCCCCCCCCC
ILLIAVASTIRHQIREIDTVARLGGDEFSVLLPAAANDAAQVVGRKLKRELADAVETRWP
EEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCC
VTFSIGMVTYITAPESVEYMIRQADQVMYEAKKSGKNRLCSVVMH
EEEEECEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]