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The map label for this gene is yciR [C]

Identifier: 118578941

GI number: 118578941

Start: 525152

End: 527269

Strand: Direct

Name: yciR [C]

Synonym: Ppro_0502

Alternate gene names: 118578941

Gene position: 525152-527269 (Clockwise)

Preceding gene: 118578940

Following gene: 118578949

Centisome position: 13.1

GC content: 62.18

Gene sequence:

>2118_bases
GTGACGAGACTTGAGCGGCAGAGCAGCGCACGCACCAGAATCCTGATCGTGGAGGATGATTGCGGTTTCGCGGAGCTGAT
GGCATCCATCCTGGAAGAGGGGGGCTTTTCCTGCTGCTGTGCCTCCAGCGGCAAGGAAGCCCTGATCTGGCTGGTCGCCC
AATCTCCCAAGCTGGTTATCCTGGATTACTCCCTGCCTGATATGACCGGAGCGTCATTGATCGAGCGGATGCGGGAGCTG
GGCGGGAATACCCCTTTCATCGTCGTGACCGGCAAGGACGACGCCAGCCTGGCGGTGGAAATGATGAAGACCGGCGCCTG
CGACTACCTGCTCAAGGACACCTCCTTCCTGGACCGCCTGCTTGCCGTTGTCGTCCGTGCCCTGCAGGAGGTCGAGACCA
GGGAACGGCTGGATCGCGCCAAGCATTCCCTGCGTCTGAGCGAGGCGCGCCTGGCCCGTGCCCAGAAGATCGCCCGTCTG
GGGAGCTGGGAATGGGACGTCAGGGCGGGAGAAATCTACTGGTCGGACGAGCTCTACCGCATCTTCGGGTTCACCCCGGG
TGAGCCGAAACGGATCAGCAAGGAGTGGATCTACAGCCTGATCCACCCGGCCGATCTGCCCGCCTTCAAGCAGCAACTGC
TCACCTCGGTCAAGACGCTCCAGTCCTTCAACATGATTTACCATACTACCTCACGCAGTGGTGGGGAGCTGGTGGTCAAC
ATCCAAGGCGAGGTGGAGCGGGGAGAGGACGGCAGGGCCTGGCTGATCTCCGGGACCGTGCTGGATATCACCGCCCGCAT
CAAGGCCGAGAGCGAGATTCACCACCTGATCAACTACGACACCCTGACCGGTCTGCCCAACCGCAGCCTGCTGCACGACC
GCCTCAGGCAGGCCATAGCCCAGGCAGCCCAGGACAGGCACATGGTCTGGGTGCTCTGCCTGGACCTGGACCGCTTCAAG
GGGGTCAACGACACCCTGGGGCACCGTTCCGGCGACAAGCTGCTCCAGGAGGTGGCCCGACGCCTGGCCGCCTGCGTGCG
CGAGAGCGATACCCTGGCCCGGCTGGGCGGCGACGAATTCGTCGTCGTGCTGGACGGGGTGGTCAGCGAGAAGGGGGCCA
GCATCGTCGCCAAGAAGATCCTTACGCTGATAGCGGAACCGATCCCCATCGACGATCACGAACTGTACACCACCGCCAGC
ATCGGCATCGCCGCCTACCCCATGGACGGCGAGGACGGCCACACCCTGCTGAAGCATGCCGACCTGGCCATGTACAAGGC
CAAGGAGCTGGACCGCAACAACTTCCACTTCTTCTCCCATGACATGAACATCAAGGTCATGGAGCGGATGATGCTGGAAA
ACTCCATGCGCAAGGCGTTGGAGCGGGACGAGTTCTTCCTGGTGTACCAGCCCCAGGTGGATGCCCGCAGCGGACGGATC
ACGGGGGTCGAGGCGCTTTTGCGCTGGAATCATCCCGACATGGGACTCTTGACCCCGGACCGGTTCATCTACCTGGCCGA
GGAAACAGGTTTCATCGTTCCGCTGGGCGAATGGGTACTGATGACCGCCTGCCGCCAGAATCGGGCCTGGCAGAAGCTGG
GCTTCCCGCCGCTGCGGGTGGCGGTCAACCTGTCCGGCAAGCAGTTCGGCCAGCATCGCCTGGACGAGATGATCTCGGCC
ATTCTGCTGGAGACCGGCCTGGAGCCGGAGTGGCTGGAACTGGAGATCACCGAGAGCGCCATCATGCGGAACGCCGACCA
GAACATCGCCATCCTACGCAGCCTGAAAGAGAAGGGCATCTCCCTGGCCATCGACGACTTCGGCACCGGCTATTCATCCC
TCTCCTACCTGAAACACTTCCCCATCACCCGCCTCAAGATCGACAAAACCTTTGTGCAGGACATCACCACCAACCCGGAT
GACGCGGCAATCGCCGAGATCATCATCGCCATGGCCCAGACCCTCAAGCTGAACGTCATCGCCGAAGGGGTCGAGACCAG
GGCCCAGATGGAGTTTCTCTCCACCCATACCTGCTTTGAAATGCAGGGCTACCTGTTCAGCCGCCCCCTCACGACGGACA
AATTCGTCTACCTGCTCAGGGACGGGATCAGCTACTGA

Upstream 100 bases:

>100_bases
CCCCAGGTGAACAGGGAAGGGTGGCGCATCAGGATGAAAAAGAAAACATGAATTCCCTGCTTCGGAAGGGGAACAGCGGA
ATGTGGCGCGGAGAACGACC

Downstream 100 bases:

>100_bases
GTCTCCCCCTTCCGCAGCACTGATCCTGAACACATCTTCCCGCCAGCCGTCGTCTGAAATGTCTGCGTGTTGGTGTCTAT
GTGGGGAAGAATGAAGGGCC

Product: response regulator receiver modulated PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 705; Mature: 704

Protein sequence:

>705_residues
MTRLERQSSARTRILIVEDDCGFAELMASILEEGGFSCCCASSGKEALIWLVAQSPKLVILDYSLPDMTGASLIERMREL
GGNTPFIVVTGKDDASLAVEMMKTGACDYLLKDTSFLDRLLAVVVRALQEVETRERLDRAKHSLRLSEARLARAQKIARL
GSWEWDVRAGEIYWSDELYRIFGFTPGEPKRISKEWIYSLIHPADLPAFKQQLLTSVKTLQSFNMIYHTTSRSGGELVVN
IQGEVERGEDGRAWLISGTVLDITARIKAESEIHHLINYDTLTGLPNRSLLHDRLRQAIAQAAQDRHMVWVLCLDLDRFK
GVNDTLGHRSGDKLLQEVARRLAACVRESDTLARLGGDEFVVVLDGVVSEKGASIVAKKILTLIAEPIPIDDHELYTTAS
IGIAAYPMDGEDGHTLLKHADLAMYKAKELDRNNFHFFSHDMNIKVMERMMLENSMRKALERDEFFLVYQPQVDARSGRI
TGVEALLRWNHPDMGLLTPDRFIYLAEETGFIVPLGEWVLMTACRQNRAWQKLGFPPLRVAVNLSGKQFGQHRLDEMISA
ILLETGLEPEWLELEITESAIMRNADQNIAILRSLKEKGISLAIDDFGTGYSSLSYLKHFPITRLKIDKTFVQDITTNPD
DAAIAEIIIAMAQTLKLNVIAEGVETRAQMEFLSTHTCFEMQGYLFSRPLTTDKFVYLLRDGISY

Sequences:

>Translated_705_residues
MTRLERQSSARTRILIVEDDCGFAELMASILEEGGFSCCCASSGKEALIWLVAQSPKLVILDYSLPDMTGASLIERMREL
GGNTPFIVVTGKDDASLAVEMMKTGACDYLLKDTSFLDRLLAVVVRALQEVETRERLDRAKHSLRLSEARLARAQKIARL
GSWEWDVRAGEIYWSDELYRIFGFTPGEPKRISKEWIYSLIHPADLPAFKQQLLTSVKTLQSFNMIYHTTSRSGGELVVN
IQGEVERGEDGRAWLISGTVLDITARIKAESEIHHLINYDTLTGLPNRSLLHDRLRQAIAQAAQDRHMVWVLCLDLDRFK
GVNDTLGHRSGDKLLQEVARRLAACVRESDTLARLGGDEFVVVLDGVVSEKGASIVAKKILTLIAEPIPIDDHELYTTAS
IGIAAYPMDGEDGHTLLKHADLAMYKAKELDRNNFHFFSHDMNIKVMERMMLENSMRKALERDEFFLVYQPQVDARSGRI
TGVEALLRWNHPDMGLLTPDRFIYLAEETGFIVPLGEWVLMTACRQNRAWQKLGFPPLRVAVNLSGKQFGQHRLDEMISA
ILLETGLEPEWLELEITESAIMRNADQNIAILRSLKEKGISLAIDDFGTGYSSLSYLKHFPITRLKIDKTFVQDITTNPD
DAAIAEIIIAMAQTLKLNVIAEGVETRAQMEFLSTHTCFEMQGYLFSRPLTTDKFVYLLRDGISY
>Mature_704_residues
TRLERQSSARTRILIVEDDCGFAELMASILEEGGFSCCCASSGKEALIWLVAQSPKLVILDYSLPDMTGASLIERMRELG
GNTPFIVVTGKDDASLAVEMMKTGACDYLLKDTSFLDRLLAVVVRALQEVETRERLDRAKHSLRLSEARLARAQKIARLG
SWEWDVRAGEIYWSDELYRIFGFTPGEPKRISKEWIYSLIHPADLPAFKQQLLTSVKTLQSFNMIYHTTSRSGGELVVNI
QGEVERGEDGRAWLISGTVLDITARIKAESEIHHLINYDTLTGLPNRSLLHDRLRQAIAQAAQDRHMVWVLCLDLDRFKG
VNDTLGHRSGDKLLQEVARRLAACVRESDTLARLGGDEFVVVLDGVVSEKGASIVAKKILTLIAEPIPIDDHELYTTASI
GIAAYPMDGEDGHTLLKHADLAMYKAKELDRNNFHFFSHDMNIKVMERMMLENSMRKALERDEFFLVYQPQVDARSGRIT
GVEALLRWNHPDMGLLTPDRFIYLAEETGFIVPLGEWVLMTACRQNRAWQKLGFPPLRVAVNLSGKQFGQHRLDEMISAI
LLETGLEPEWLELEITESAIMRNADQNIAILRSLKEKGISLAIDDFGTGYSSLSYLKHFPITRLKIDKTFVQDITTNPDD
AAIAEIIIAMAQTLKLNVIAEGVETRAQMEFLSTHTCFEMQGYLFSRPLTTDKFVYLLRDGISY

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=441, Percent_Identity=41.2698412698413, Blast_Score=337, Evalue=2e-93,
Organism=Escherichia coli, GI87081921, Length=431, Percent_Identity=37.8190255220418, Blast_Score=269, Evalue=5e-73,
Organism=Escherichia coli, GI226510982, Length=417, Percent_Identity=34.052757793765, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI87081980, Length=250, Percent_Identity=37.6, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1788502, Length=254, Percent_Identity=35.4330708661417, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI87081845, Length=250, Percent_Identity=34.8, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1787055, Length=431, Percent_Identity=26.6821345707657, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786507, Length=238, Percent_Identity=34.0336134453782, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1790496, Length=249, Percent_Identity=33.7349397590361, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI87081743, Length=241, Percent_Identity=33.6099585062241, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1788849, Length=245, Percent_Identity=34.6938775510204, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI87082096, Length=423, Percent_Identity=26.0047281323877, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI87081977, Length=153, Percent_Identity=35.9477124183007, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788381, Length=208, Percent_Identity=33.1730769230769, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786584, Length=156, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=34.0782122905028, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI145693134, Length=162, Percent_Identity=35.1851851851852, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787802, Length=161, Percent_Identity=34.1614906832298, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI87082007, Length=157, Percent_Identity=32.484076433121, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1787816, Length=161, Percent_Identity=31.6770186335404, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1787262, Length=158, Percent_Identity=32.9113924050633, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788956, Length=152, Percent_Identity=34.8684210526316, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=34.7107438016529, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081974, Length=85, Percent_Identity=40, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787410, Length=124, Percent_Identity=33.0645161290323, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=115, Percent_Identity=33.0434782608696, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787487, Length=133, Percent_Identity=33.8345864661654, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1789402, Length=148, Percent_Identity=30.4054054054054, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI87082012, Length=168, Percent_Identity=30.3571428571429, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 79466; Mature: 79334

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLERQSSARTRILIVEDDCGFAELMASILEEGGFSCCCASSGKEALIWLVAQSPKLVI
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCEEE
LDYSLPDMTGASLIERMRELGGNTPFIVVTGKDDASLAVEMMKTGACDYLLKDTSFLDRL
EECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
LAVVVRALQEVETRERLDRAKHSLRLSEARLARAQKIARLGSWEWDVRAGEIYWSDELYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEECCCEEE
IFGFTPGEPKRISKEWIYSLIHPADLPAFKQQLLTSVKTLQSFNMIYHTTSRSGGELVVN
EECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEE
IQGEVERGEDGRAWLISGTVLDITARIKAESEIHHLINYDTLTGLPNRSLLHDRLRQAIA
EECCCCCCCCCCEEEEECEEEEEEEEECCHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHH
QAAQDRHMVWVLCLDLDRFKGVNDTLGHRSGDKLLQEVARRLAACVRESDTLARLGGDEF
HHHCCCCEEEEEEEEHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCE
VVVLDGVVSEKGASIVAKKILTLIAEPIPIDDHELYTTASIGIAAYPMDGEDGHTLLKHA
EEEEECHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEECCCCCCCCHHHHHH
DLAMYKAKELDRNNFHFFSHDMNIKVMERMMLENSMRKALERDEFFLVYQPQVDARSGRI
HHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCC
TGVEALLRWNHPDMGLLTPDRFIYLAEETGFIVPLGEWVLMTACRQNRAWQKLGFPPLRV
HHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEECHHHHHHHHHHCCCCHHHCCCCCEEE
AVNLSGKQFGQHRLDEMISAILLETGLEPEWLELEITESAIMRNADQNIAILRSLKEKGI
EEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHCCCCHHHHHHHHHHCCC
SLAIDDFGTGYSSLSYLKHFPITRLKIDKTFVQDITTNPDDAAIAEIIIAMAQTLKLNVI
EEEEECCCCCHHHHHHHHHCCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEE
AEGVETRAQMEFLSTHTCFEMQGYLFSRPLTTDKFVYLLRDGISY
HHHHHHHHHHHHHHHHHHHEECCCEEECCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
TRLERQSSARTRILIVEDDCGFAELMASILEEGGFSCCCASSGKEALIWLVAQSPKLVI
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCCCEEE
LDYSLPDMTGASLIERMRELGGNTPFIVVTGKDDASLAVEMMKTGACDYLLKDTSFLDRL
EECCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
LAVVVRALQEVETRERLDRAKHSLRLSEARLARAQKIARLGSWEWDVRAGEIYWSDELYR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEECCCEEE
IFGFTPGEPKRISKEWIYSLIHPADLPAFKQQLLTSVKTLQSFNMIYHTTSRSGGELVVN
EECCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEE
IQGEVERGEDGRAWLISGTVLDITARIKAESEIHHLINYDTLTGLPNRSLLHDRLRQAIA
EECCCCCCCCCCEEEEECEEEEEEEEECCHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHH
QAAQDRHMVWVLCLDLDRFKGVNDTLGHRSGDKLLQEVARRLAACVRESDTLARLGGDEF
HHHCCCCEEEEEEEEHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCE
VVVLDGVVSEKGASIVAKKILTLIAEPIPIDDHELYTTASIGIAAYPMDGEDGHTLLKHA
EEEEECHHCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCEEEECCCCCCCCHHHHHH
DLAMYKAKELDRNNFHFFSHDMNIKVMERMMLENSMRKALERDEFFLVYQPQVDARSGRI
HHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCC
TGVEALLRWNHPDMGLLTPDRFIYLAEETGFIVPLGEWVLMTACRQNRAWQKLGFPPLRV
HHHHHHHCCCCCCCCCCCCCCEEEEECCCCEEEECHHHHHHHHHHCCCCHHHCCCCCEEE
AVNLSGKQFGQHRLDEMISAILLETGLEPEWLELEITESAIMRNADQNIAILRSLKEKGI
EEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHHHHCCCCHHHHHHHHHHCCC
SLAIDDFGTGYSSLSYLKHFPITRLKIDKTFVQDITTNPDDAAIAEIIIAMAQTLKLNVI
EEEEECCCCCHHHHHHHHHCCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEE
AEGVETRAQMEFLSTHTCFEMQGYLFSRPLTTDKFVYLLRDGISY
HHHHHHHHHHHHHHHHHHHEECCCEEECCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]