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The map label for this gene is gtaB [H]

Identifier: 118578920

GI number: 118578920

Start: 503287

End: 504150

Strand: Direct

Name: gtaB [H]

Synonym: Ppro_0481

Alternate gene names: 118578920

Gene position: 503287-504150 (Clockwise)

Preceding gene: 118578919

Following gene: 118578923

Centisome position: 12.56

GC content: 60.65

Gene sequence:

>864_bases
ATGAAGGTCAGAAAAGCCGTTTTCCCCGTTGCCGGACTGGGCACCCGATTTCTTCCCGCCACAAAGTCGTCGCCAAAGGA
GATGCTGCCGCTGATCGACAAACCGCTGGTACAGTATGTGGTGGAGGAGGCGGTTGCCTCGGGCATCGAGCAGGTCCTGT
TCGTCACCGGCCGCGGCAAGCGCTCCATCGAGGACCACTTCGACATCTCCGTGGAGTTGGAGGCGCATCTCAACGGCCAG
GGCAAGGCGCGGGAACTGTCCAGTGTCCGCAGGATCGCCGAGATGGCGGAGATCTTCTACGTGCGCCAGCGCCAGGCGCT
GGGTCTTGGCCACGCCATCCTCTGCGCCAGGGATTTCATCGGCAACGAACCCTTTGCCGTGCTGCTGGGTGATGACATCA
TCGACAGCCAACGCCCCTGTCTGCGCCAGTTGCTGGATGTGTTCGAAGAGCACAACGGCTCGGTGCTTGCCCTGGAAAAG
GTGCCGATGGAGAATATCTCATCCTATGGTTGCGTGCGTGCCACCGCCCTGTCCGATCGGGTCTTCGACGTGCTGGATAT
GGTGGAGAAGCCGAGTCGGGCGGAAGCCCCCTCGGATATGGCCATCATCGGTCGCTACGTGCTGACCCCGGCCATATTCG
ACATCCTCATGCAACAGCAGCCGGGCAAGGGGGGCGAGATACAGCTCACCGACGCGGTTCTGACCCTGTCCAAGGAAGAA
AAGGTCTATGGTTGTCTGTTTGAGGGGTTGCGCCACGATTGCGGCGACAAGCTGGGATTTCTGAAGGCAACGGTTGATAT
GGCCCTGAAGCGGGACGAGTTTCGCGAGGAGCTTTCGGCGTATCTTCGTGAGCGGCTGGGGTGA

Upstream 100 bases:

>100_bases
GAGGGGCATGGCGGAATAGGGCGCGAAGCAGGGAAACAGTAGCTGCCTGTCGTTTGTGTGTCGTGCAATTGCCGAATATT
TCATCTGGAGGTCTGCATCC

Downstream 100 bases:

>100_bases
TGCTCCGACCTGGATTGCGTGAATAAAGAAAGGCGAGCCCTGCGGGGCTCGCCTTTTTGTTATTGCTGTGCCGCTTCCGG
CTGTGGCTGTGGGTTTTCTC

Product: UTP-glucose-1-phosphate uridylyltransferase GalU

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKVRKAVFPVAGLGTRFLPATKSSPKEMLPLIDKPLVQYVVEEAVASGIEQVLFVTGRGKRSIEDHFDISVELEAHLNGQ
GKARELSSVRRIAEMAEIFYVRQRQALGLGHAILCARDFIGNEPFAVLLGDDIIDSQRPCLRQLLDVFEEHNGSVLALEK
VPMENISSYGCVRATALSDRVFDVLDMVEKPSRAEAPSDMAIIGRYVLTPAIFDILMQQQPGKGGEIQLTDAVLTLSKEE
KVYGCLFEGLRHDCGDKLGFLKATVDMALKRDEFREELSAYLRERLG

Sequences:

>Translated_287_residues
MKVRKAVFPVAGLGTRFLPATKSSPKEMLPLIDKPLVQYVVEEAVASGIEQVLFVTGRGKRSIEDHFDISVELEAHLNGQ
GKARELSSVRRIAEMAEIFYVRQRQALGLGHAILCARDFIGNEPFAVLLGDDIIDSQRPCLRQLLDVFEEHNGSVLALEK
VPMENISSYGCVRATALSDRVFDVLDMVEKPSRAEAPSDMAIIGRYVLTPAIFDILMQQQPGKGGEIQLTDAVLTLSKEE
KVYGCLFEGLRHDCGDKLGFLKATVDMALKRDEFREELSAYLRERLG
>Mature_287_residues
MKVRKAVFPVAGLGTRFLPATKSSPKEMLPLIDKPLVQYVVEEAVASGIEQVLFVTGRGKRSIEDHFDISVELEAHLNGQ
GKARELSSVRRIAEMAEIFYVRQRQALGLGHAILCARDFIGNEPFAVLLGDDIIDSQRPCLRQLLDVFEEHNGSVLALEK
VPMENISSYGCVRATALSDRVFDVLDMVEKPSRAEAPSDMAIIGRYVLTPAIFDILMQQQPGKGGEIQLTDAVLTLSKEE
KVYGCLFEGLRHDCGDKLGFLKATVDMALKRDEFREELSAYLRERLG

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in the S.aureus membrane, which is also used as a mem

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=261, Percent_Identity=26.8199233716475, Blast_Score=65, Evalue=9e-11,
Organism=Homo sapiens, GI11761619, Length=261, Percent_Identity=27.2030651340996, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1787488, Length=295, Percent_Identity=44.7457627118644, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI1788355, Length=294, Percent_Identity=41.156462585034, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1790224, Length=234, Percent_Identity=24.7863247863248, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788351, Length=238, Percent_Identity=25.2100840336134, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 31895; Mature: 31895

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRKAVFPVAGLGTRFLPATKSSPKEMLPLIDKPLVQYVVEEAVASGIEQVLFVTGRGK
CCCHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
RSIEDHFDISVELEAHLNGQGKARELSSVRRIAEMAEIFYVRQRQALGLGHAILCARDFI
CCCHHHCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GNEPFAVLLGDDIIDSQRPCLRQLLDVFEEHNGSVLALEKVPMENISSYGCVRATALSDR
CCCCEEEEECCHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCHHHHHHHHH
VFDVLDMVEKPSRAEAPSDMAIIGRYVLTPAIFDILMQQQPGKGGEIQLTDAVLTLSKEE
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCHH
KVYGCLFEGLRHDCGDKLGFLKATVDMALKRDEFREELSAYLRERLG
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVRKAVFPVAGLGTRFLPATKSSPKEMLPLIDKPLVQYVVEEAVASGIEQVLFVTGRGK
CCCHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
RSIEDHFDISVELEAHLNGQGKARELSSVRRIAEMAEIFYVRQRQALGLGHAILCARDFI
CCCHHHCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GNEPFAVLLGDDIIDSQRPCLRQLLDVFEEHNGSVLALEKVPMENISSYGCVRATALSDR
CCCCEEEEECCHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCCHHHHHHHHH
VFDVLDMVEKPSRAEAPSDMAIIGRYVLTPAIFDILMQQQPGKGGEIQLTDAVLTLSKEE
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHCCHH
KVYGCLFEGLRHDCGDKLGFLKATVDMALKRDEFREELSAYLRERLG
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA