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The map label for this gene is ribB

Identifier: 118578754

GI number: 118578754

Start: 311535

End: 312239

Strand: Direct

Name: ribB

Synonym: Ppro_0312

Alternate gene names: 118578754

Gene position: 311535-312239 (Clockwise)

Preceding gene: 118578752

Following gene: 118578755

Centisome position: 7.77

GC content: 65.39

Gene sequence:

>705_bases
ATGAATCAGTCGTATTTCCCCCACCATCAATCCGATCTCTCACTGCAACGCGTGGAGGCTGCGCTGGATGCGCTGCGCGC
GGGCCAAGGCGTGCTGGTCACCGACGACGAACAGCGCGAAAACGAGGGCGACCTGATCTTCGCCGCCCAGAGCCTGACCA
GGGAGCAGGTCGCCATGCTGATCCGCGAGTGCAGTGGCATCGTCTGTCTCTGTCTGACCGACGAGGCGGTGCGTCGCCTG
GACCTTCCCCTGATGGTCAGTGACAACAGCAGCCGCTACCAGACCGCCTTCACCGTCTCCATCGAGGCGGCGGAAGGGGT
GACCACTGGCGTGTCCGCCGCCGACCGCCTGACCACCATCCGGGCAGCCATTGCCGACGATGCCGGCCCCTTGTGCCTCA
GCCGTCCCGGCCATGTCTTCCCCTTGCGTGCCCGCCCCGGCGGGGTGCTGGAGCGCCGGGGGCACACCGAGGCGACCGTC
GACCTGATGCGCCTTGCGGGCCTGAAGCCGTGCGGGGTGCTGTGCGAGTTGACCAATCCGGACGGCAGCATGGCGCGTAT
GCCCGAAATTGTTGCCTTTTCAAGGAAGCATGGTTTCCCGCTGATCACGGTGGAGGAGTTGGTGCAATACCGCATTGTTC
GGGAACAGCCGGCCGCCTTGCTGCAAGCTGAAGCCGAAAGCGCTGGTGCGCTCTGTTCCGCGTAG

Upstream 100 bases:

>100_bases
ATCGGTATTCCCGTGGCCGGGGCTGTTCGGCCGCGCGCCGACAGCTGCCCGTTCCGTAGCCCTGATTCTGGTAAGCCACC
ATATTCCCGGAGGTAGAACC

Downstream 100 bases:

>100_bases
AGGGGAGGCCAGATGCAGACAGAGGAATTGGATGTCAGGACGGAGCGGCGCAGCCAATTCGTCGATATCACCGCTCGGGT
CGGGGAGCTGGTTGGCGTCA

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNQSYFPHHQSDLSLQRVEAALDALRAGQGVLVTDDEQRENEGDLIFAAQSLTREQVAMLIRECSGIVCLCLTDEAVRRL
DLPLMVSDNSSRYQTAFTVSIEAAEGVTTGVSAADRLTTIRAAIADDAGPLCLSRPGHVFPLRARPGGVLERRGHTEATV
DLMRLAGLKPCGVLCELTNPDGSMARMPEIVAFSRKHGFPLITVEELVQYRIVREQPAALLQAEAESAGALCSA

Sequences:

>Translated_234_residues
MNQSYFPHHQSDLSLQRVEAALDALRAGQGVLVTDDEQRENEGDLIFAAQSLTREQVAMLIRECSGIVCLCLTDEAVRRL
DLPLMVSDNSSRYQTAFTVSIEAAEGVTTGVSAADRLTTIRAAIADDAGPLCLSRPGHVFPLRARPGGVLERRGHTEATV
DLMRLAGLKPCGVLCELTNPDGSMARMPEIVAFSRKHGFPLITVEELVQYRIVREQPAALLQAEAESAGALCSA
>Mature_234_residues
MNQSYFPHHQSDLSLQRVEAALDALRAGQGVLVTDDEQRENEGDLIFAAQSLTREQVAMLIRECSGIVCLCLTDEAVRRL
DLPLMVSDNSSRYQTAFTVSIEAAEGVTTGVSAADRLTTIRAAIADDAGPLCLSRPGHVFPLRARPGGVLERRGHTEATV
DLMRLAGLKPCGVLCELTNPDGSMARMPEIVAFSRKHGFPLITVEELVQYRIVREQPAALLQAEAESAGALCSA

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family

Homologues:

Organism=Escherichia coli, GI1789420, Length=219, Percent_Identity=62.5570776255708, Blast_Score=280, Evalue=5e-77,
Organism=Saccharomyces cerevisiae, GI6320695, Length=201, Percent_Identity=46.7661691542289, Blast_Score=188, Evalue=6e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIBB_PELPD (A1AKS6)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_900004.1
- ProteinModelPortal:   A1AKS6
- SMR:   A1AKS6
- STRING:   A1AKS6
- GeneID:   4573164
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_0312
- eggNOG:   COG0108
- HOGENOM:   HBG735778
- OMA:   RGHTEAT
- PhylomeDB:   A1AKS6
- HAMAP:   MF_00180
- InterPro:   IPR017945
- InterPro:   IPR000422
- Gene3D:   G3DSA:3.90.870.10
- TIGRFAMs:   TIGR00506

Pfam domain/function: PF00926 DHBP_synthase; SSF55821 DHBP_synth_RibB-like_a/b_dom

EC number: =4.1.99.12

Molecular weight: Translated: 25286; Mature: 25286

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: BINDING 44-44 BINDING 176-176

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSYFPHHQSDLSLQRVEAALDALRAGQGVLVTDDEQRENEGDLIFAAQSLTREQVAML
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEHHHHHHHHHHHH
IRECSGIVCLCLTDEAVRRLDLPLMVSDNSSRYQTAFTVSIEAAEGVTTGVSAADRLTTI
HHHCCCEEEEEECHHHHHHCCCCEEECCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHH
RAAIADDAGPLCLSRPGHVFPLRARPGGVLERRGHTEATVDLMRLAGLKPCGVLCELTNP
HHHHHCCCCCEEECCCCCEEEECCCCCCCHHCCCCCHHHHHHHHHCCCCCCCEEEEEECC
DGSMARMPEIVAFSRKHGFPLITVEELVQYRIVREQPAALLQAEAESAGALCSA
CCCHHHCCHHHHHHHCCCCCEEEHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNQSYFPHHQSDLSLQRVEAALDALRAGQGVLVTDDEQRENEGDLIFAAQSLTREQVAML
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEHHHHHHHHHHHH
IRECSGIVCLCLTDEAVRRLDLPLMVSDNSSRYQTAFTVSIEAAEGVTTGVSAADRLTTI
HHHCCCEEEEEECHHHHHHCCCCEEECCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHH
RAAIADDAGPLCLSRPGHVFPLRARPGGVLERRGHTEATVDLMRLAGLKPCGVLCELTNP
HHHHHCCCCCEEECCCCCEEEECCCCCCCHHCCCCCHHHHHHHHHCCCCCCCEEEEEECC
DGSMARMPEIVAFSRKHGFPLITVEELVQYRIVREQPAALLQAEAESAGALCSA
CCCHHHCCHHHHHHHCCCCCEEEHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA