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The map label for this gene is ccpA [H]

Identifier: 118479818

GI number: 118479818

Start: 4477332

End: 4478342

Strand: Reverse

Name: ccpA [H]

Synonym: BALH_4255

Alternate gene names: 118479818

Gene position: 4478342-4477332 (Counterclockwise)

Preceding gene: 118479819

Following gene: 118479812

Centisome position: 85.19

GC content: 38.77

Gene sequence:

>1011_bases
GTGTGCGATGAGATGAACGTAACAATATATGATGTAGCGCGCGAAGCGAACGTTTCAATGGCTACCGTATCTCGTGTTGT
GAACGGTAACCCAAATGTAAAGCCTACAACAAGAAAGAAAGTATTAGAAGCAATTGATCGTTTAGGATACCGCCCAAATG
CGGTAGCACGTGGACTAGCAAGTAAAAAGACGACTACAGTAGGTGTTATTATTCCTGATATCTCAAATACGTTTTATGCA
GAACTTGCTCGTGGAATTGAAGATATCGCAACAATGTACAAATATAACATCATTTTAAGTAACTCTGACCAAAACAAAGA
GAAAGAGTTCCATTTATTAAATACGATGCTTGGAAAACAAGTGGACGGAATTGTTTTTATGGGTGAAGATATTACAGATA
TTCACGCTGAAGAATTTAAAAAGTCTCCAGTACCAATCGTATTAGCAGCGTCATTTGATGAGCAAAATGAAACGCCATCA
GTAAACATTGATTATACACAAGCAGCTTACGACGCAATGAAGCACTTTATTGAACAAGGACATAAGCGTATCGGTTTCGT
CTCTGGTCCTTTCATTGATAAAGCGGGAAGTGCGAAGAAGTTACAAGGTTATAGAAAAGCTCTAGAAGAAGCAGGTATTT
CATATGATGAAAATCTTGTAATCGATGGAGATTACACATATGACTCAGGTATAGAAGCATTCGAAAAGCTTTGGAGCCTT
GATGAAAAGCCAACAGCGATCTTCGTATCTTCTGACGAAATGGCACTAGGTGTAATCCACGCAGCACAAGACGCTGGATT
AAACGTACCAACTGATGTAGAAGTACTTGGATTCGATAATACACGCCTTGCATTAATGGTTCGTCCGCAACTTTCAACAG
TTGTACAACCGATGTATGATATCGGTGCAGTAGCAATGCGTCTATTAACAAAGTATATGAACAAAGAAAAAGTGGAAGAT
CACACTGTTATCTTACCTCACCGTATCCAATTTAGAGATTCAACGAAGTAA

Upstream 100 bases:

>100_bases
GGAAGAACTCGGGACGATTGGTGGCATCTGCAAATAGAGTTGATGTCTTTTTTTCATTCAAGTAACCGATACATAAAAAT
AGATAGCAAAAATAGAAGGA

Downstream 100 bases:

>100_bases
GTATAAAAAAAGCTCACAGCGATTGCTGTGAGCTTTTATTTATATTCAGGATAGTATGTTTGAATTATAGTATCCACCGT
TTCATTTTTCTTAACGTGTA

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Glucose-resistance amylase regulator [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MCDEMNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIDRLGYRPNAVARGLASKKTTTVGVIIPDISNTFYA
ELARGIEDIATMYKYNIILSNSDQNKEKEFHLLNTMLGKQVDGIVFMGEDITDIHAEEFKKSPVPIVLAASFDEQNETPS
VNIDYTQAAYDAMKHFIEQGHKRIGFVSGPFIDKAGSAKKLQGYRKALEEAGISYDENLVIDGDYTYDSGIEAFEKLWSL
DEKPTAIFVSSDEMALGVIHAAQDAGLNVPTDVEVLGFDNTRLALMVRPQLSTVVQPMYDIGAVAMRLLTKYMNKEKVED
HTVILPHRIQFRDSTK

Sequences:

>Translated_336_residues
MCDEMNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIDRLGYRPNAVARGLASKKTTTVGVIIPDISNTFYA
ELARGIEDIATMYKYNIILSNSDQNKEKEFHLLNTMLGKQVDGIVFMGEDITDIHAEEFKKSPVPIVLAASFDEQNETPS
VNIDYTQAAYDAMKHFIEQGHKRIGFVSGPFIDKAGSAKKLQGYRKALEEAGISYDENLVIDGDYTYDSGIEAFEKLWSL
DEKPTAIFVSSDEMALGVIHAAQDAGLNVPTDVEVLGFDNTRLALMVRPQLSTVVQPMYDIGAVAMRLLTKYMNKEKVED
HTVILPHRIQFRDSTK
>Mature_336_residues
MCDEMNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIDRLGYRPNAVARGLASKKTTTVGVIIPDISNTFYA
ELARGIEDIATMYKYNIILSNSDQNKEKEFHLLNTMLGKQVDGIVFMGEDITDIHAEEFKKSPVPIVLAASFDEQNETPS
VNIDYTQAAYDAMKHFIEQGHKRIGFVSGPFIDKAGSAKKLQGYRKALEEAGISYDENLVIDGDYTYDSGIEAFEKLWSL
DEKPTAIFVSSDEMALGVIHAAQDAGLNVPTDVEVLGFDNTRLALMVRPQLSTVVQPMYDIGAVAMRLLTKYMNKEKVED
HTVILPHRIQFRDSTK

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (AmyE) and the acetyl-coenzyme A synthetase (AcsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=334, Percent_Identity=36.8263473053892, Blast_Score=231, Evalue=5e-62,
Organism=Escherichia coli, GI1787948, Length=329, Percent_Identity=34.6504559270517, Blast_Score=191, Evalue=7e-50,
Organism=Escherichia coli, GI1790194, Length=321, Percent_Identity=32.7102803738318, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1789068, Length=307, Percent_Identity=32.2475570032573, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1789202, Length=291, Percent_Identity=32.6460481099656, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1788474, Length=302, Percent_Identity=30.4635761589404, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1787580, Length=329, Percent_Identity=26.7477203647416, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI48994940, Length=304, Percent_Identity=27.3026315789474, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786540, Length=333, Percent_Identity=28.2282282282282, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790715, Length=318, Percent_Identity=23.8993710691824, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787906, Length=271, Percent_Identity=26.9372693726937, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789456, Length=354, Percent_Identity=27.683615819209, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786268, Length=314, Percent_Identity=25.1592356687898, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI1790689, Length=331, Percent_Identity=23.2628398791541, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37394; Mature: 37394

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCDEMNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIDRLGYRPNAVARGLA
CCCCCCEEEEEEHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCC
SKKTTTVGVIIPDISNTFYAELARGIEDIATMYKYNIILSNSDQNKEKEFHLLNTMLGKQ
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHCCC
VDGIVFMGEDITDIHAEEFKKSPVPIVLAASFDEQNETPSVNIDYTQAAYDAMKHFIEQG
CCCEEEECCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEECHHHHHHHHHHHHHHHC
HKRIGFVSGPFIDKAGSAKKLQGYRKALEEAGISYDENLVIDGDYTYDSGIEAFEKLWSL
HHEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCC
DEKPTAIFVSSDEMALGVIHAAQDAGLNVPTDVEVLGFDNTRLALMVRPQLSTVVQPMYD
CCCCCEEEEECCCEEEEEEEEHHCCCCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHHH
IGAVAMRLLTKYMNKEKVEDHTVILPHRIQFRDSTK
HHHHHHHHHHHHHCHHCCCCCEEEECCEEECCCCCC
>Mature Secondary Structure
MCDEMNVTIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIDRLGYRPNAVARGLA
CCCCCCEEEEEEHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCC
SKKTTTVGVIIPDISNTFYAELARGIEDIATMYKYNIILSNSDQNKEKEFHLLNTMLGKQ
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHCCC
VDGIVFMGEDITDIHAEEFKKSPVPIVLAASFDEQNETPSVNIDYTQAAYDAMKHFIEQG
CCCEEEECCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEECHHHHHHHHHHHHHHHC
HKRIGFVSGPFIDKAGSAKKLQGYRKALEEAGISYDENLVIDGDYTYDSGIEAFEKLWSL
HHEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCHHHHHHHHHHCC
DEKPTAIFVSSDEMALGVIHAAQDAGLNVPTDVEVLGFDNTRLALMVRPQLSTVVQPMYD
CCCCCEEEEECCCEEEEEEEEHHCCCCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHHH
IGAVAMRLLTKYMNKEKVEDHTVILPHRIQFRDSTK
HHHHHHHHHHHHHCHHCCCCCEEEECCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1904524; 9387221; 9384377 [H]