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The map label for this gene is gltC [H]

Identifier: 118479791

GI number: 118479791

Start: 4453563

End: 4454423

Strand: Reverse

Name: gltC [H]

Synonym: BALH_4228

Alternate gene names: 118479791

Gene position: 4454423-4453563 (Counterclockwise)

Preceding gene: 118479793

Following gene: 118479790

Centisome position: 84.73

GC content: 37.98

Gene sequence:

>861_bases
TTGTTAGAGGTGTGTACGATGGATTTGGAGGCAGTACGATCGTTTATTGAAGTGAAGAATACGCGAAGTTTATCAAAGGC
GAGTAAGATTTTACATATTTCTCAGCCGGCGCTTAGTAAACAAATTCAAAGGTTAGAAGCGGATTTAGAGGTTACTTTAC
TGAAGCGTTCCGCGCAAGGAGTAGAATTAACAAGTGCTGGAGAGTTATTTATAAAAAGAATGTTACCGGTTTTGGAACAC
ATACATGAAGTGAAAGCTGAAATGAAGAAGTTTCAAGAGAAGAGGAACATTTCGATAGGCATATTGCCAAGTTTAGCAGC
ACATTACATATCAAAATGTAAAGATATATTAGGTGACGGGTTCGAAGTAGAATGGAAAATTGAGCATACGAAAGTACTGA
TGGGACTGTTTAAAGAACGGAAGATTGAAGCGATCTTCATCGATTCAGTAGTAGAAGGCGCTACGTGTATAAAAGAAATA
CGAGAAGAAAAAATTGTTTGTGTCGTTTCAAATGATCATCTTTATAAAGAGAAAACAGTAATCCGAATGGAAGATTTGCA
AAATGAAAAGTTAATCGTATACCCAGAAATCTGTGATGTTAGGAAAATGATTACGAATATGTTTCAAGGGATAGGTGCGA
AACCGATCATTGCATTTGAAACTTCTTATGCAGAACCGATGCTTGCGATGGTTGGTGCTGGACTTGGTATCACGTTACTT
CCAGAAATGTCAGTAGAGCAAGCGGTAAAGCAAGGGAATGTGCATGCCATTTCTATTGAACCGCCACTTGTGCGCAAAAT
TTATTTCGTATCTCATATGGAAGAAGGCCCTTTGTTGCATTCATTTGATGATGAGAGGTAA

Upstream 100 bases:

>100_bases
CTTTCCCCTTTACATTTCGTTATAGTAAGTTGATGAAATAAGTATAAAGAGTAATTGTTTATAGAAGGAAATACTGATTT
TTTATGACAGTTATAACTTT

Downstream 100 bases:

>100_bases
TCCAAACGGAATATTGAGAAAGATTACAATTGCATTGAAAGAAACATGAAATTTTAAAAAAAACTAGGTCAAAAACAAGC
CATTACATGGTATGATTAGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MLEVCTMDLEAVRSFIEVKNTRSLSKASKILHISQPALSKQIQRLEADLEVTLLKRSAQGVELTSAGELFIKRMLPVLEH
IHEVKAEMKKFQEKRNISIGILPSLAAHYISKCKDILGDGFEVEWKIEHTKVLMGLFKERKIEAIFIDSVVEGATCIKEI
REEKIVCVVSNDHLYKEKTVIRMEDLQNEKLIVYPEICDVRKMITNMFQGIGAKPIIAFETSYAEPMLAMVGAGLGITLL
PEMSVEQAVKQGNVHAISIEPPLVRKIYFVSHMEEGPLLHSFDDER

Sequences:

>Translated_286_residues
MLEVCTMDLEAVRSFIEVKNTRSLSKASKILHISQPALSKQIQRLEADLEVTLLKRSAQGVELTSAGELFIKRMLPVLEH
IHEVKAEMKKFQEKRNISIGILPSLAAHYISKCKDILGDGFEVEWKIEHTKVLMGLFKERKIEAIFIDSVVEGATCIKEI
REEKIVCVVSNDHLYKEKTVIRMEDLQNEKLIVYPEICDVRKMITNMFQGIGAKPIIAFETSYAEPMLAMVGAGLGITLL
PEMSVEQAVKQGNVHAISIEPPLVRKIYFVSHMEEGPLLHSFDDER
>Mature_286_residues
MLEVCTMDLEAVRSFIEVKNTRSLSKASKILHISQPALSKQIQRLEADLEVTLLKRSAQGVELTSAGELFIKRMLPVLEH
IHEVKAEMKKFQEKRNISIGILPSLAAHYISKCKDILGDGFEVEWKIEHTKVLMGLFKERKIEAIFIDSVVEGATCIKEI
REEKIVCVVSNDHLYKEKTVIRMEDLQNEKLIVYPEICDVRKMITNMFQGIGAKPIIAFETSYAEPMLAMVGAGLGITLL
PEMSVEQAVKQGNVHAISIEPPLVRKIYFVSHMEEGPLLHSFDDER

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=272, Percent_Identity=27.2058823529412, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788887, Length=287, Percent_Identity=27.8745644599303, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI2367136, Length=250, Percent_Identity=23.2, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI145693105, Length=276, Percent_Identity=23.5507246376812, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI157672245, Length=267, Percent_Identity=22.4719101123595, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787879, Length=252, Percent_Identity=23.8095238095238, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787601, Length=97, Percent_Identity=38.1443298969072, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788297, Length=107, Percent_Identity=30.8411214953271, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32374; Mature: 32374

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEVCTMDLEAVRSFIEVKNTRSLSKASKILHISQPALSKQIQRLEADLEVTLLKRSAQG
CCEEECCCHHHHHHHHHHHCCHHHHHHHHHEECCCHHHHHHHHHHHCCHHHEEEHHCCCC
VELTSAGELFIKRMLPVLEHIHEVKAEMKKFQEKRNISIGILPSLAAHYISKCKDILGDG
CEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCC
FEVEWKIEHTKVLMGLFKERKIEAIFIDSVVEGATCIKEIREEKIVCVVSNDHLYKEKTV
CEEEEEEHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCEEEEEECCCEEHHHHE
IRMEDLQNEKLIVYPEICDVRKMITNMFQGIGAKPIIAFETSYAEPMLAMVGAGLGITLL
EEECCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHCCCCCEEEC
PEMSVEQAVKQGNVHAISIEPPLVRKIYFVSHMEEGPLLHSFDDER
CCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLEVCTMDLEAVRSFIEVKNTRSLSKASKILHISQPALSKQIQRLEADLEVTLLKRSAQG
CCEEECCCHHHHHHHHHHHCCHHHHHHHHHEECCCHHHHHHHHHHHCCHHHEEEHHCCCC
VELTSAGELFIKRMLPVLEHIHEVKAEMKKFQEKRNISIGILPSLAAHYISKCKDILGDG
CEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHCCC
FEVEWKIEHTKVLMGLFKERKIEAIFIDSVVEGATCIKEIREEKIVCVVSNDHLYKEKTV
CEEEEEEHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCEEEEEECCCEEHHHHE
IRMEDLQNEKLIVYPEICDVRKMITNMFQGIGAKPIIAFETSYAEPMLAMVGAGLGITLL
EEECCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHCCCCCEEEC
PEMSVEQAVKQGNVHAISIEPPLVRKIYFVSHMEEGPLLHSFDDER
CCCCHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]