| Definition | Bacillus thuringiensis str. Al Hakam chromosome, complete genome. |
|---|---|
| Accession | NC_008600 |
| Length | 5,257,091 |
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The map label for this gene is polA [H]
Identifier: 118479734
GI number: 118479734
Start: 4389733
End: 4392408
Strand: Reverse
Name: polA [H]
Synonym: BALH_4171
Alternate gene names: 118479734
Gene position: 4392408-4389733 (Counterclockwise)
Preceding gene: 118479735
Following gene: 118479733
Centisome position: 83.55
GC content: 36.51
Gene sequence:
>2676_bases GTGAAAAAAATCATTTCAAATTTGTATGGGGAGGTTTCTCATTTGGAAAAAAAGGTCGTATTAGTAGATGGTAATAATAT CGCGTATCGTGCTTTCTTTGCACTACCGCTTTTAAATAACGACAAAGGTATACATACGAACGCAATTTACGGTTTTACAA TGATGTTAATGAGAATATTAGAGGAAGAAAAACCGACGCATATGTTAGTAGCATTTGATGCGGGGAAAACGACATTCCGT CATAAAACATATAGTGAGTATAAAGGGGGACGTCAAAAGACTCCGCCTGAGTTATCAGAGCAATTCCCGTTTATTCGTGA GATGCTTGATGCATTTAACGTACCGCGTTATGAATTAGAAAATTATGAAGCGGATGACATTATGGGAACGCTAGCGAAAG AAGCGAGTGAACAAGGCGCAAGTGTAAAAGTTATTTCAGGAGATAAAGACTTACTTCAACTTGTTTCTGATAACACGCTT GTATGTATTCCTCGAAAAGGGATTACGGAAGTAGACGAATATACGAAAGAAGCTTTATTTGAAAAATACAGCTTATCACC AAAGCAAATTATCGATATGAAAGGTTTAATGGGAGACCAATCAGATAATATTCCAGGTGTACCAGGAGTTGGTGAAAAAA CTGCGATTAAATTGTTAACACAGTTTGGAACGGTTGAAGAAGTGTATGAAAATATAGATCAAGTAAGCGGGAAGAAATTA AAGGAAAAGCTGGAAGCAAATAAAGACCAAGCTCTTATGAGTAAAGATCTTGCAACCATTATTACAGACGCACCGATTAC TGTGAATGTGGATGATATGGAGTATAAAGGATATGAAGCAAGTGATGTCATTCCAATGTTCGAGAATTTAGGATTTACAT CTCTTTTAAACAAATTAGGTGTTACGCCAGAAGAAACGGCTCCAGCTGAATTAGATGATATTACATTTGATATTGTAGAA GAAGTTACAGAAGAAATGCTTCAGCAAGATAGTGCTCTTATCGTTGAAGTACAAGAAGATAACTATCATAAAGCAGACAT TCAAGGTTTCGGTATTCAAAATGAAAATGGATGTTACTTTATTCAGACAGACATTGCACTTAAATCAGATGCTTTTAAAG AGTGGCTTGCAGATGGAGAAATGAGAAAGTATACATTTGATGCGAAGCGTGCGATCGTTGCGCTGAAATGGAACGGTATA GATATGCAAGGGATTGACTTTGATCTATTAATCGCTGCTTACTTACTTGACCCGGCTGATACAGATAAAGATTTCCGTAC TGTAGCGAAAATGAAAGAAACGCATGCTGTGAAATCTGATGAAGAAGTTTACGGAAAAGGTGCGAAGCGTGCTGTTCCAG AGTTAGAGATAGTAGCGGAGCATGTAGCTCGTAAAGTGCATGTATTATATGATGTAAAGCAAACATTCGTTGAAGAGTTA GAAAAGAATGAGCAATATGAACTGTTTACAGAGTTGGAATTACCACTTGCACGTGTATTAGCTGATATGGAAGTAAAAGG TGTAAAAGTTGATACAGAACGTCTTCGTAATATGGGAGAAGAACTTGCAGGTAGATTAAAGGAAATGGAACAGGAAATTT ATAAGCTAGCGGGAACAGAATTTAATATTAATTCACCGAAGCAGCTTGGTGTGATTCTGTTTGAGAATTTAAACTTACCG GTTATTAAGAAGACAAAAACAGGTTATTCTACGTCAGCTGATGTACTAGACAAGCTGATGGATCACCATGAAATTATTCC AAACATTTTACATTACCGTCAATTAGGGAAACTAAATTCAACTTATATTGAAGGTTTATTAAAAGTTGTACATGAAGATT CATCTAAAATTCATACTCGCTTCAATCAAGTATTAACGCAAACAGGTCGATTAAGTTCAACGGATCCAAACTTGCAAAAT ATCCCGATTCGATTAGAAGAAGGAAGAAAGATTCGTCAGGCATTCGTTCCATCAGAAGAAGGATGGATTATGTACGCGGC CGATTATTCACAAATTGAACTTCGTGTATTAGCTCATATTGCCAATGATAAAGGGCTAGTTGAAGCGTTCAAACATGACA TGGATATTCATACAAAAACAGCTATGGATGTATTTGGCGTTGAAAAAGATGAAGTAACTTCAAATATGAGACGACAAGCG AAAGCTGTTAACTTCGGAATTGTGTATGGTATTAGTGATTATGGTCTTTCACAAAACTTAGGAATTACAAGAAAAGCAGC AGCGGAATTTATTGAAAAGTATTTAGAAAGTTTCCCTGGTGTACAAGAATACATGGATGACATCGTAAAAGATGCGAAAC AAAAAGGATATGTAGCTACATTATTAAATCGCCGCCGTTACATTCCGGAAATTACGAGTCGTAATTTCAACTTGCGTAGC TTTGCTGAGCGTACAGCTATGAATACACCAATTCAAGGTACTGCAGCAGATATTATTAAAAAAGCGATGATTATTATGGC AGATCGTTTAGAAGAAGAAGGATTACAAGCTCGTCTTCTTCTGCAAGTACACGATGAATTAATATTTGAGGCACCAAAAG AAGAAATTGAAAAATTAGAGAAGCTTGTACCAGAAGTAATGGAGCATGCAATTGAACTGGCAGTTCCACTGAAAGTTGAT TATTCTTACGGTCCAACTTGGTACGACGCAAAATAA
Upstream 100 bases:
>100_bases AATATAAGTCTGTTTTATATATGAAAGAAAAATAACCGTTATTTTTCTTCTCTCTATTAGTCATGTTAATATAGAGAGAG GAAAGAAACGGTTTTTTTCT
Downstream 100 bases:
>100_bases GGAAGTGATGAAATGCCTGAATTACCAGAGGTTGAAAACGTCAGACGGACACTTGAAAATCTTGTAACAGGAAAAACAAT TGAAGACGTCATTGTTACCT
Product: DNA polymerase I
Products: NA
Alternate protein names: POL I [H]
Number of amino acids: Translated: 891; Mature: 891
Protein sequence:
>891_residues MKKIISNLYGEVSHLEKKVVLVDGNNIAYRAFFALPLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAFDAGKTTFR HKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLAKEASEQGASVKVISGDKDLLQLVSDNTL VCIPRKGITEVDEYTKEALFEKYSLSPKQIIDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKL KEKLEANKDQALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAELDDITFDIVE EVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIALKSDAFKEWLADGEMRKYTFDAKRAIVALKWNGI DMQGIDFDLLIAAYLLDPADTDKDFRTVAKMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEEL EKNEQYELFTELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQLGVILFENLNLP VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLLKVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQN IPIRLEEGRKIRQAFVPSEEGWIMYAADYSQIELRVLAHIANDKGLVEAFKHDMDIHTKTAMDVFGVEKDEVTSNMRRQA KAVNFGIVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRRYIPEITSRNFNLRS FAERTAMNTPIQGTAADIIKKAMIIMADRLEEEGLQARLLLQVHDELIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVD YSYGPTWYDAK
Sequences:
>Translated_891_residues MKKIISNLYGEVSHLEKKVVLVDGNNIAYRAFFALPLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAFDAGKTTFR HKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLAKEASEQGASVKVISGDKDLLQLVSDNTL VCIPRKGITEVDEYTKEALFEKYSLSPKQIIDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKL KEKLEANKDQALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAELDDITFDIVE EVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIALKSDAFKEWLADGEMRKYTFDAKRAIVALKWNGI DMQGIDFDLLIAAYLLDPADTDKDFRTVAKMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEEL EKNEQYELFTELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQLGVILFENLNLP VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLLKVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQN IPIRLEEGRKIRQAFVPSEEGWIMYAADYSQIELRVLAHIANDKGLVEAFKHDMDIHTKTAMDVFGVEKDEVTSNMRRQA KAVNFGIVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRRYIPEITSRNFNLRS FAERTAMNTPIQGTAADIIKKAMIIMADRLEEEGLQARLLLQVHDELIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVD YSYGPTWYDAK >Mature_891_residues MKKIISNLYGEVSHLEKKVVLVDGNNIAYRAFFALPLLNNDKGIHTNAIYGFTMMLMRILEEEKPTHMLVAFDAGKTTFR HKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELENYEADDIMGTLAKEASEQGASVKVISGDKDLLQLVSDNTL VCIPRKGITEVDEYTKEALFEKYSLSPKQIIDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKL KEKLEANKDQALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLGVTPEETAPAELDDITFDIVE EVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYFIQTDIALKSDAFKEWLADGEMRKYTFDAKRAIVALKWNGI DMQGIDFDLLIAAYLLDPADTDKDFRTVAKMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEEL EKNEQYELFTELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTEFNINSPKQLGVILFENLNLP VIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNSTYIEGLLKVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQN IPIRLEEGRKIRQAFVPSEEGWIMYAADYSQIELRVLAHIANDKGLVEAFKHDMDIHTKTAMDVFGVEKDEVTSNMRRQA KAVNFGIVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVATLLNRRRYIPEITSRNFNLRS FAERTAMNTPIQGTAADIIKKAMIIMADRLEEEGLQARLLLQVHDELIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVD YSYGPTWYDAK
Specific function: In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' and 5' to 3' exonuclease activity [H]
COG id: COG0749
COG function: function code L; DNA polymerase I - 3'-5' exonuclease and polymerase domains
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 5'-3' exonuclease domain [H]
Homologues:
Organism=Homo sapiens, GI112420958, Length=516, Percent_Identity=34.1085271317829, Blast_Score=265, Evalue=1e-70, Organism=Homo sapiens, GI139394648, Length=634, Percent_Identity=26.6561514195584, Blast_Score=213, Evalue=5e-55, Organism=Escherichia coli, GI1790294, Length=925, Percent_Identity=37.7297297297297, Blast_Score=561, Evalue=1e-161, Organism=Escherichia coli, GI226510970, Length=225, Percent_Identity=32, Blast_Score=124, Evalue=2e-29, Organism=Caenorhabditis elegans, GI86563272, Length=410, Percent_Identity=28.5365853658537, Blast_Score=176, Evalue=4e-44, Organism=Drosophila melanogaster, GI17933644, Length=419, Percent_Identity=33.1742243436754, Blast_Score=237, Evalue=3e-62,
Paralogues:
None
Copy number: 400 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002562 - InterPro: IPR020046 - InterPro: IPR020045 - InterPro: IPR002421 - InterPro: IPR020047 - InterPro: IPR019760 - InterPro: IPR001098 - InterPro: IPR018320 - InterPro: IPR002298 - InterPro: IPR008918 - InterPro: IPR003583 - InterPro: IPR012337 [H]
Pfam domain/function: PF01367 5_3_exonuc; PF02739 5_3_exonuc_N; PF00476 DNA_pol_A [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 101016; Mature: 101016
Theoretical pI: Translated: 4.70; Mature: 4.70
Prosite motif: PS00447 DNA_POLYMERASE_A
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 3.3 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKKIISNLYGEVSHLEKKVVLVDGNNIAYRAFFALPLLNNDKGIHTNAIYGFTMMLMRIL CHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHH EEEKPTHMLVAFDAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELE HCCCCCEEEEEEECCCCHHCCCCHHHHCCCCCCCCCCHHHCCHHHHHHHHHHCCCCHHHC NYEADDIMGTLAKEASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALF CCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHH EKYSLSPKQIIDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKL HHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHH KEKLEANKDQALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLG HHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHCCCHHHHHHHHC VTPEETAPAELDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYF CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEECCCCCCCCEEE IQTDIALKSDAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPAD EEECCHHHHHHHHHHHCCCCHHEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCC TDKDFRTVAKMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEEL CCHHHHHHHHHHHHHCCCCCHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH EKNEQYELFTELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTE HCCCCEEHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCC FNINSPKQLGVILFENLNLPVIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNS CCCCCCHHCCEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH TYIEGLLKVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEE HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCHHHHHCCCCCC GWIMYAADYSQIELRVLAHIANDKGLVEAFKHDMDIHTKTAMDVFGVEKDEVTSNMRRQA CEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHH KAVNFGIVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVAT HHHCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHH LLNRRRYIPEITSRNFNLRSFAERTAMNTPIQGTAADIIKKAMIIMADRLEEEGLQARLL HHHHHHCCCHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH LQVHDELIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCC >Mature Secondary Structure MKKIISNLYGEVSHLEKKVVLVDGNNIAYRAFFALPLLNNDKGIHTNAIYGFTMMLMRIL CHHHHHHHHHHHHHCCCEEEEEECCCEEEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHH EEEKPTHMLVAFDAGKTTFRHKTYSEYKGGRQKTPPELSEQFPFIREMLDAFNVPRYELE HCCCCCEEEEEEECCCCHHCCCCHHHHCCCCCCCCCCHHHCCHHHHHHHHHHCCCCHHHC NYEADDIMGTLAKEASEQGASVKVISGDKDLLQLVSDNTLVCIPRKGITEVDEYTKEALF CCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHH EKYSLSPKQIIDMKGLMGDQSDNIPGVPGVGEKTAIKLLTQFGTVEEVYENIDQVSGKKL HHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHH KEKLEANKDQALMSKDLATIITDAPITVNVDDMEYKGYEASDVIPMFENLGFTSLLNKLG HHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHCCCHHHHHHHHC VTPEETAPAELDDITFDIVEEVTEEMLQQDSALIVEVQEDNYHKADIQGFGIQNENGCYF CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEECCCCCCCCEEE IQTDIALKSDAFKEWLADGEMRKYTFDAKRAIVALKWNGIDMQGIDFDLLIAAYLLDPAD EEECCHHHHHHHHHHHCCCCHHEEEECCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCC TDKDFRTVAKMKETHAVKSDEEVYGKGAKRAVPELEIVAEHVARKVHVLYDVKQTFVEEL CCHHHHHHHHHHHHHCCCCCHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH EKNEQYELFTELELPLARVLADMEVKGVKVDTERLRNMGEELAGRLKEMEQEIYKLAGTE HCCCCEEHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCC FNINSPKQLGVILFENLNLPVIKKTKTGYSTSADVLDKLMDHHEIIPNILHYRQLGKLNS CCCCCCHHCCEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH TYIEGLLKVVHEDSSKIHTRFNQVLTQTGRLSSTDPNLQNIPIRLEEGRKIRQAFVPSEE HHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCHHHHHCCCCCC GWIMYAADYSQIELRVLAHIANDKGLVEAFKHDMDIHTKTAMDVFGVEKDEVTSNMRRQA CEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHH KAVNFGIVYGISDYGLSQNLGITRKAAAEFIEKYLESFPGVQEYMDDIVKDAKQKGYVAT HHHCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHH LLNRRRYIPEITSRNFNLRSFAERTAMNTPIQGTAADIIKKAMIIMADRLEEEGLQARLL HHHHHHCCCHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH LQVHDELIFEAPKEEIEKLEKLVPEVMEHAIELAVPLKVDYSYGPTWYDAK HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9387221; 9384377 [H]