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The map label for this gene is speD

Identifier: 118479729

GI number: 118479729

Start: 4385620

End: 4386012

Strand: Reverse

Name: speD

Synonym: BALH_4165

Alternate gene names: 118479729

Gene position: 4386012-4385620 (Counterclockwise)

Preceding gene: 118479730

Following gene: 118479728

Centisome position: 83.43

GC content: 41.98

Gene sequence:

>393_bases
ATGGATACTATGGATACGATGGGTCGTCACGTGATTGCTGAACTTTGGGATTGCGATTTCGACAAGCTTAATGACATGCC
GTATATTGAACAATTATTTGTGGATGCAGCACTAAGAGCTGGTGCTGAAGTGCGTGAGGTTGCTTTCCATAAATTTGCAC
CACAAGGTGTAAGTGGAGTAGTAATTATCTCGGAATCACATTTAACAATTCATAGCTTTCCGGAGCACGGTTACGCAAGT
ATTGATGTTTATACTTGTGGGGATCGTATTGATCCAAATGTTGCTGCAGAATATATTGCAGAAGGTTTAAACGCGAAAAC
GCGTGAGAGCATCGAGCTTCCTCGAGGCACTGGTAGCTTCGAAATTAAGCAGAGAGAAACAAAAGCTCTTTAA

Upstream 100 bases:

>100_bases
TCTCTGGACTAACTTTCCCCCGTGGTAGTGGAGCAAGCCAAATTGCAAATTAGTTTTCAATTCGAACAGTTAGAATAAAT
TTACAAGGGGGAACTGTAGA

Downstream 100 bases:

>100_bases
AAAAGAACATAATTGATTTAAAATGTAAAGAGGTGTATAATGCACCTCTTTTTTAGTTTATAAAAAAGGGAAAATATAAC
GTACTCGTTAGTTGAATAAA

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC 1; SAMDC 1

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MDTMDTMGRHVIAELWDCDFDKLNDMPYIEQLFVDAALRAGAEVREVAFHKFAPQGVSGVVIISESHLTIHSFPEHGYAS
IDVYTCGDRIDPNVAAEYIAEGLNAKTRESIELPRGTGSFEIKQRETKAL

Sequences:

>Translated_130_residues
MDTMDTMGRHVIAELWDCDFDKLNDMPYIEQLFVDAALRAGAEVREVAFHKFAPQGVSGVVIISESHLTIHSFPEHGYAS
IDVYTCGDRIDPNVAAEYIAEGLNAKTRESIELPRGTGSFEIKQRETKAL
>Mature_130_residues
MDTMDTMGRHVIAELWDCDFDKLNDMPYIEQLFVDAALRAGAEVREVAFHKFAPQGVSGVVIISESHLTIHSFPEHGYAS
IDVYTCGDRIDPNVAAEYIAEGLNAKTRESIELPRGTGSFEIKQRETKAL

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEH1_BACAN (Q81L09)

Other databases:

- EMBL:   AE016879
- EMBL:   AE017334
- EMBL:   AE017225
- RefSeq:   NP_847028.1
- RefSeq:   YP_021471.1
- RefSeq:   YP_030724.1
- ProteinModelPortal:   Q81L09
- SMR:   Q81L09
- EnsemblBacteria:   EBBACT00000009865
- EnsemblBacteria:   EBBACT00000017661
- EnsemblBacteria:   EBBACT00000022768
- GeneID:   1083964
- GeneID:   2815159
- GeneID:   2851569
- GenomeReviews:   AE016879_GR
- GenomeReviews:   AE017225_GR
- GenomeReviews:   AE017334_GR
- KEGG:   ban:BA_4825
- KEGG:   bar:GBAA_4825
- KEGG:   bat:BAS4477
- TIGR:   BA_4825
- TIGR:   GBAA_4825
- GeneTree:   EBGT00050000001345
- HOGENOM:   HBG485559
- OMA:   RTHKFSP
- ProtClustDB:   PRK03124
- BioCyc:   BANT260799:BAS4477-MONOMER
- BioCyc:   BANT261594:GBAA4825-MONOMER
- BRENDA:   4.1.1.50
- HAMAP:   MF_00464
- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716
- Gene3D:   G3DSA:3.60.90.10
- TIGRFAMs:   TIGR03330

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 14487; Mature: 14487

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: ACT_SITE 66-66 ACT_SITE 71-71 ACT_SITE 86-86

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTMDTMGRHVIAELWDCDFDKLNDMPYIEQLFVDAALRAGAEVREVAFHKFAPQGVSGV
CCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEE
VIISESHLTIHSFPEHGYASIDVYTCGDRIDPNVAAEYIAEGLNAKTRESIELPRGTGSF
EEEECCCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEECCCCCCCE
EIKQRETKAL
EEECCCCCCC
>Mature Secondary Structure
MDTMDTMGRHVIAELWDCDFDKLNDMPYIEQLFVDAALRAGAEVREVAFHKFAPQGVSGV
CCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCEE
VIISESHLTIHSFPEHGYASIDVYTCGDRIDPNVAAEYIAEGLNAKTRESIELPRGTGSF
EEEECCCEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEECCCCCCCE
EIKQRETKAL
EEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629