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The map label for this gene is obgE

Identifier: 118479596

GI number: 118479596

Start: 4237711

End: 4238997

Strand: Reverse

Name: obgE

Synonym: BALH_4023

Alternate gene names: 118479596

Gene position: 4238997-4237711 (Counterclockwise)

Preceding gene: 118479597

Following gene: 118479595

Centisome position: 80.63

GC content: 42.35

Gene sequence:

>1287_bases
ATGTTTGTAGATCAGGTCAAGATATATGTAAAAGGCGGCGACGGTGGTAACGGAATGGTTGCGTATCGTCGTGAGAAGTA
TGTACCAAAAGGTGGCCCAGCAGGTGGCGACGGTGGTAAAGGTGCAGATGTTGTTTTTATTGTTGAGGAAGGCTTACGTA
CATTAATGGACTTCCGCTACCAACGTCATTTCAAAGCTGATCGCGGTCAGCACGGAATGAGTAAAGGTCAGCACGGACGT
AAATCTGAAGATTTACTTGTAAAGGTTCCGCCAGGAACAGTAGTAAAAGATGAAAAAACTGGTCAAATTCTTGCGGATTT
AGTAACGCATGGACAAACGGCTGTAATTGCAAAAGGTGGCCGCGGTGGTCGTGGTAACTCACGTTTCGCAACAGCTACGA
ACCCAGCGCCAGAAATCGCTGAAAACGGGGAACCAGGTCAAGAGCGTGATGTCATTCTAGAACTGAAAGTACTGGCAGAC
GTTGGACTTGTTGGATTCCCAAGTGTAGGTAAATCTACATTATTATCTGTCGTATCATCAGCACGTCCGAAAATTGCAGA
GTATCACTTCACAACAATCGTTCCAAACCTTGGTGTTGTTGAAACTGGTGATAACCGCAGCTTCGTTATGGCTGACCTTC
CTGGACTAATTGAAGGCGCACATGCTGGCGTCGGACTTGGACACCAATTCTTACGTCATATTGAGCGTACACGTGTAATC
GTGCATGTTATTGATATGTCTGGTTTAGAAGGCCGTGATCCATATGAAGATTACGTAACAATTAATAATGAATTAAAAGA
ATACAATCTTCGCTTAACGGAGCGTCCACAAGTTGTTGTTGCAAACAAAATGGATATGCCAGATGCAGAAGAAAACTTAC
AAGCATTTAAAGAGAAAGTGGGAGACGAAGTAAAAATCTTCCCAATCTCAGCTGTAACGAAACAAGGTGTTCGTGACTTA
CTGTTTGAAGTAGCGAACTTAATAGAAACAACACCTGAATTCCCAATACATGAAGTTGTTGATGAGTCTGACACAAGTGT
AATGTACAAATTTGAGACTGAAGGTGTTAAATTTGATATTACACGTGAAAGTGATGGTACGTTTGTTATCTCTGGTTACG
ATATCGAGAAAACATTCAAGATGACAGACTTCTCACGTGATGAATCTGTACGTCGTTTCGCTCGCCAAATGCGCGGAATG
GGTATTGATGAAGCGCTTCGTGCACGTGGTGCAAAAGACGGAGATATTGTAAAAATTCTTGAATATGAATTTGAATTTAT
CGACTAA

Upstream 100 bases:

>100_bases
TTGCGAACCAAAACAATAAATGGTATTCCATTTCTTATACAGTACGAGACGAGGAAGTCTCAGTTATATTACAACCAATT
GAAAAAAGTGTGGTGAAATA

Downstream 100 bases:

>100_bases
GACTGCCGAAATACGGCAGTCTTTTTTTATATCGTAAAAGTCTGATTTATACAGGAAAAAATCCCCACTAATTAAATTTT
CAATTTATAATAGAAAAAGA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MFVDQVKIYVKGGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFIVEEGLRTLMDFRYQRHFKADRGQHGMSKGQHGR
KSEDLLVKVPPGTVVKDEKTGQILADLVTHGQTAVIAKGGRGGRGNSRFATATNPAPEIAENGEPGQERDVILELKVLAD
VGLVGFPSVGKSTLLSVVSSARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVI
VHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKVGDEVKIFPISAVTKQGVRDL
LFEVANLIETTPEFPIHEVVDESDTSVMYKFETEGVKFDITRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGM
GIDEALRARGAKDGDIVKILEYEFEFID

Sequences:

>Translated_428_residues
MFVDQVKIYVKGGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFIVEEGLRTLMDFRYQRHFKADRGQHGMSKGQHGR
KSEDLLVKVPPGTVVKDEKTGQILADLVTHGQTAVIAKGGRGGRGNSRFATATNPAPEIAENGEPGQERDVILELKVLAD
VGLVGFPSVGKSTLLSVVSSARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVI
VHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKVGDEVKIFPISAVTKQGVRDL
LFEVANLIETTPEFPIHEVVDESDTSVMYKFETEGVKFDITRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGM
GIDEALRARGAKDGDIVKILEYEFEFID
>Mature_428_residues
MFVDQVKIYVKGGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFIVEEGLRTLMDFRYQRHFKADRGQHGMSKGQHGR
KSEDLLVKVPPGTVVKDEKTGQILADLVTHGQTAVIAKGGRGGRGNSRFATATNPAPEIAENGEPGQERDVILELKVLAD
VGLVGFPSVGKSTLLSVVSSARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVI
VHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKVGDEVKIFPISAVTKQGVRDL
LFEVANLIETTPEFPIHEVVDESDTSVMYKFETEGVKFDITRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGM
GIDEALRARGAKDGDIVKILEYEFEFID

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=334, Percent_Identity=40.4191616766467, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI111955139, Length=347, Percent_Identity=36.0230547550432, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI111955063, Length=236, Percent_Identity=36.864406779661, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4758796, Length=118, Percent_Identity=38.135593220339, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI58761500, Length=129, Percent_Identity=34.1085271317829, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI4557537, Length=90, Percent_Identity=44.4444444444444, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1789574, Length=351, Percent_Identity=47.008547008547, Blast_Score=301, Evalue=5e-83,
Organism=Escherichia coli, GI1787454, Length=138, Percent_Identity=35.5072463768116, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508313, Length=321, Percent_Identity=37.6947040498442, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=312, Percent_Identity=31.0897435897436, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=31.6546762589928, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71981008, Length=118, Percent_Identity=36.4406779661017, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=35.5932203389831, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=194, Percent_Identity=37.1134020618557, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=38.8888888888889, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321649, Length=141, Percent_Identity=29.7872340425532, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321612, Length=126, Percent_Identity=32.5396825396825, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24585318, Length=309, Percent_Identity=40.1294498381877, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI20129375, Length=304, Percent_Identity=40.1315789473684, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI21356473, Length=163, Percent_Identity=34.3558282208589, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI17981711, Length=127, Percent_Identity=34.6456692913386, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_BACAH (A0RJ47)

Other databases:

- EMBL:   CP000485
- RefSeq:   YP_896747.1
- ProteinModelPortal:   A0RJ47
- SMR:   A0RJ47
- STRING:   A0RJ47
- EnsemblBacteria:   EBBACT00000066957
- GeneID:   4544612
- GenomeReviews:   CP000485_GR
- KEGG:   btl:BALH_4023
- eggNOG:   COG0536
- GeneTree:   EBGT00050000000577
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- ProtClustDB:   PRK12297
- BioCyc:   BTHU412694:BALH_4023-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 47211; Mature: 47211

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDQVKIYVKGGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFIVEEGLRTLMDFRY
CCCCEEEEEEEECCCCCCEEEEEHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHH
QRHFKADRGQHGMSKGQHGRKSEDLLVKVPPGTVVKDEKTGQILADLVTHGQTAVIAKGG
HHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCHHHHHHHHHHCCCEEEEEECC
RGGRGNSRFATATNPAPEIAENGEPGQERDVILELKVLADVGLVGFPSVGKSTLLSVVSS
CCCCCCCEEEECCCCCCHHHCCCCCCCCCCEEEEEEEHHHCCCCCCCCCCHHHHHHHHHH
ARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVI
CCCCHHEEEEEEECCCCCEEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
VHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKV
EEEEECCCCCCCCCCHHEEEECCCCEECCCEECCCCCEEEEECCCCCCHHHHHHHHHHHC
GDEVKIFPISAVTKQGVRDLLFEVANLIETTPEFPIHEVVDESDTSVMYKFETEGVKFDI
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCEEEEE
TRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGMGIDEALRARGAKDGDIVKIL
EECCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEE
EYEFEFID
EEEEEECC
>Mature Secondary Structure
MFVDQVKIYVKGGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFIVEEGLRTLMDFRY
CCCCEEEEEEEECCCCCCEEEEEHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHH
QRHFKADRGQHGMSKGQHGRKSEDLLVKVPPGTVVKDEKTGQILADLVTHGQTAVIAKGG
HHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCHHHHHHHHHHCCCEEEEEECC
RGGRGNSRFATATNPAPEIAENGEPGQERDVILELKVLADVGLVGFPSVGKSTLLSVVSS
CCCCCCCEEEECCCCCCHHHCCCCCCCCCCEEEEEEEHHHCCCCCCCCCCHHHHHHHHHH
ARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVI
CCCCHHEEEEEEECCCCCEEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
VHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKV
EEEEECCCCCCCCCCHHEEEECCCCEECCCEECCCCCEEEEECCCCCCHHHHHHHHHHHC
GDEVKIFPISAVTKQGVRDLLFEVANLIETTPEFPIHEVVDESDTSVMYKFETEGVKFDI
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCEEEEE
TRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGMGIDEALRARGAKDGDIVKIL
EECCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEE
EYEFEFID
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA