Click here to switch to the map view.

The map label for this gene is glcD [H]

Identifier: 118478773

GI number: 118478773

Start: 3344885

End: 3346276

Strand: Reverse

Name: glcD [H]

Synonym: BALH_3165

Alternate gene names: 118478773

Gene position: 3346276-3344885 (Counterclockwise)

Preceding gene: 118478774

Following gene: 118478772

Centisome position: 63.65

GC content: 38.58

Gene sequence:

>1392_bases
ATGGGAATAACAGTAGAGCGTTTAGTAAATGAATTAAAGGGTGTACTTCCCGAAGATCGAGTAGTAATCAATACGACAGT
AAGAGAGTTACATAGTAAAGATGAATCTTACCATGCCAGTAGTTTACCTGATGTAGTAGTTTTTCCGAAAACGACAGAAG
AGGTTAGCACGATAATGAAAATAGCGAGTGAGCACGGAACACCTGTCGTTCCGTTTGGGGTAGGTTCTAGTTTAGAAGGA
CATGTAATCCCTTATGAAAAGGGAATTACAGTTGATTTTTCATTAATGAACAAAATTCTTGAAATAAGAGAGAAAGATTT
TCTGGTGAAAGTACAGCCAGGAGTGACTCGTTCTCAGCTCAATAAAGAATTGAAGAAATACGGTTTGTTTTTTAGTGTAG
ATCCAGGGGCAGATGCAACGTTAGGTGGAATGGCTGCTACAAATGCAAGTGGAACGACAGCGGTGAAGTATGGTGTTATG
CGTGATCAAGTTCGTGATTTAGAAGTCGTTCTTGCTGATGGAGAAGTAATACATACTGGGAATTTAGCTGCGAAGTCGTC
ATCAGGTTACCATTTAAATGGTGTTTTCGTAGGATCAGAAGGTACGCTTGGATGCTTTACAGAGTTAACATTAAAAGTAT
ATGGCATACCAGAGCATGTTATGGCCGCAAGAGCATCGTTTCCGGCTATAAATGATGCAGTAGAAGCTGTTATTAACATA
TTGCAAGCGGGTATTCCGATTGCGAGAATTGAACTCGTTGATGAACTATCTATGAAACAAGTCAATCATTATAGTGAAAC
AAGTTACAGAGAAGAACCTACATTGTTTTTAGAGTTTCACGGTAATGAAGCAGGGTTAAAGCAAGATGTTGAATTTACGA
AGGAAATTGTTTTTGATCAAAAATGTAAAGAAGTTGCTTTTGAAACGGAAACTGCTGCGAGAAATAAATTATGGGATGCA
CGGCATAATCTAGCATATGCTTACGTTCATAGCTATCCTGGTAAAAAGCTTATGAGTACAGACGTATGTGTACCTATTTC
AGAATTAGCTGGAGCTATCCAACAAGCGAAAGAGACATTAGAAAAGAATGGTCTTGTTGGTGGTATTCTTGGTCATGTAG
GAGACGGGAATTTCCACGTGCTCTTAATGGTTGATCCAAACGATAAAGAAGAAGTGGAAAAAGCGGATGAAATAAATGAA
AGTATCGTTCTATATGCTCTTAAACGAGGAGGAACATGTACAGGGGAACATGGCGTTGGTATTGGAAAACGGAAGTATCA
GGAAGAAGAACATGGGGCGGCATTATTCGTAATGGAAAAAATAAAGAAAGCTCTTGATCCGCAAAATATTTTGAATCCGA
ATAAGGTGTTTCAATTAAAGGATAGGAGCTGA

Upstream 100 bases:

>100_bases
GTATATGTAAAGCTTGAATTATTTAATTTTTCGGATTATTATGTATAAAACACTTAACATATTTTGTAATTCAAATTTAT
AGAGAATAGGAGAGTGTACG

Downstream 100 bases:

>100_bases
TCGGGTGAAAGTACTAGAAGCGATAAGTAATATAGCTGGAAAGTATTTTGCATTTTGGGTTATTTGTATTGCAACTATTG
CGTATTTTATTCCCGCTCCA

Product: glycolate oxidase, subunit D

Products: pyruvate; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MGITVERLVNELKGVLPEDRVVINTTVRELHSKDESYHASSLPDVVVFPKTTEEVSTIMKIASEHGTPVVPFGVGSSLEG
HVIPYEKGITVDFSLMNKILEIREKDFLVKVQPGVTRSQLNKELKKYGLFFSVDPGADATLGGMAATNASGTTAVKYGVM
RDQVRDLEVVLADGEVIHTGNLAAKSSSGYHLNGVFVGSEGTLGCFTELTLKVYGIPEHVMAARASFPAINDAVEAVINI
LQAGIPIARIELVDELSMKQVNHYSETSYREEPTLFLEFHGNEAGLKQDVEFTKEIVFDQKCKEVAFETETAARNKLWDA
RHNLAYAYVHSYPGKKLMSTDVCVPISELAGAIQQAKETLEKNGLVGGILGHVGDGNFHVLLMVDPNDKEEVEKADEINE
SIVLYALKRGGTCTGEHGVGIGKRKYQEEEHGAALFVMEKIKKALDPQNILNPNKVFQLKDRS

Sequences:

>Translated_463_residues
MGITVERLVNELKGVLPEDRVVINTTVRELHSKDESYHASSLPDVVVFPKTTEEVSTIMKIASEHGTPVVPFGVGSSLEG
HVIPYEKGITVDFSLMNKILEIREKDFLVKVQPGVTRSQLNKELKKYGLFFSVDPGADATLGGMAATNASGTTAVKYGVM
RDQVRDLEVVLADGEVIHTGNLAAKSSSGYHLNGVFVGSEGTLGCFTELTLKVYGIPEHVMAARASFPAINDAVEAVINI
LQAGIPIARIELVDELSMKQVNHYSETSYREEPTLFLEFHGNEAGLKQDVEFTKEIVFDQKCKEVAFETETAARNKLWDA
RHNLAYAYVHSYPGKKLMSTDVCVPISELAGAIQQAKETLEKNGLVGGILGHVGDGNFHVLLMVDPNDKEEVEKADEINE
SIVLYALKRGGTCTGEHGVGIGKRKYQEEEHGAALFVMEKIKKALDPQNILNPNKVFQLKDRS
>Mature_462_residues
GITVERLVNELKGVLPEDRVVINTTVRELHSKDESYHASSLPDVVVFPKTTEEVSTIMKIASEHGTPVVPFGVGSSLEGH
VIPYEKGITVDFSLMNKILEIREKDFLVKVQPGVTRSQLNKELKKYGLFFSVDPGADATLGGMAATNASGTTAVKYGVMR
DQVRDLEVVLADGEVIHTGNLAAKSSSGYHLNGVFVGSEGTLGCFTELTLKVYGIPEHVMAARASFPAINDAVEAVINIL
QAGIPIARIELVDELSMKQVNHYSETSYREEPTLFLEFHGNEAGLKQDVEFTKEIVFDQKCKEVAFETETAARNKLWDAR
HNLAYAYVHSYPGKKLMSTDVCVPISELAGAIQQAKETLEKNGLVGGILGHVGDGNFHVLLMVDPNDKEEVEKADEINES
IVLYALKRGGTCTGEHGVGIGKRKYQEEEHGAALFVMEKIKKALDPQNILNPNKVFQLKDRS

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=454, Percent_Identity=47.7973568281938, Blast_Score=444, Evalue=1e-124,
Organism=Homo sapiens, GI37595754, Length=477, Percent_Identity=45.2830188679245, Blast_Score=434, Evalue=1e-121,
Organism=Homo sapiens, GI119964728, Length=433, Percent_Identity=26.7898383371824, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI4501993, Length=219, Percent_Identity=30.1369863013699, Blast_Score=106, Evalue=5e-23,
Organism=Escherichia coli, GI1789351, Length=466, Percent_Identity=29.8283261802575, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1787977, Length=499, Percent_Identity=27.8557114228457, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI48994907, Length=492, Percent_Identity=24.5934959349593, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71992373, Length=458, Percent_Identity=43.2314410480349, Blast_Score=380, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI71992381, Length=458, Percent_Identity=42.3580786026201, Blast_Score=366, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71992392, Length=361, Percent_Identity=46.814404432133, Blast_Score=333, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI17534361, Length=453, Percent_Identity=26.7108167770419, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17556096, Length=452, Percent_Identity=25.6637168141593, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6320027, Length=474, Percent_Identity=37.9746835443038, Blast_Score=314, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6320764, Length=470, Percent_Identity=25.3191489361702, Blast_Score=135, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6320023, Length=473, Percent_Identity=25.369978858351, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI18921117, Length=431, Percent_Identity=26.2180974477958, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24639277, Length=431, Percent_Identity=26.2180974477958, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24639275, Length=431, Percent_Identity=26.2180974477958, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24653753, Length=219, Percent_Identity=31.0502283105023, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: 1.1.2.4

Molecular weight: Translated: 50725; Mature: 50594

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGITVERLVNELKGVLPEDRVVINTTVRELHSKDESYHASSLPDVVVFPKTTEEVSTIMK
CCEEHHHHHHHHHCCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHH
IASEHGTPVVPFGVGSSLEGHVIPYEKGITVDFSLMNKILEIREKDFLVKVQPGVTRSQL
HHHHCCCEEEEECCCCCCCCCEEECCCCCEEEHHHHHHHHHHHCCCEEEEECCCCCHHHH
NKELKKYGLFFSVDPGADATLGGMAATNASGTTAVKYGVMRDQVRDLEVVLADGEVIHTG
HHHHHHHCCEEEECCCCCCCCCCEEECCCCCCHHEEHHHHHHHHCCEEEEEECCCEEECC
NLAAKSSSGYHLNGVFVGSEGTLGCFTELTLKVYGIPEHVMAARASFPAINDAVEAVINI
CCEECCCCCEEEEEEEECCCCCEEEHEEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHH
LQAGIPIARIELVDELSMKQVNHYSETSYREEPTLFLEFHGNEAGLKQDVEFTKEIVFDQ
HHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
KCKEVAFETETAARNKLWDARHNLAYAYVHSYPGKKLMSTDVCVPISELAGAIQQAKETL
HHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHH
EKNGLVGGILGHVGDGNFHVLLMVDPNDKEEVEKADEINESIVLYALKRGGTCTGEHGVG
HHCCCEEEHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCC
IGKRKYQEEEHGAALFVMEKIKKALDPQNILNPNKVFQLKDRS
CCHHHCCHHHCCCCHHHHHHHHHHCCHHHCCCCCCEEEECCCC
>Mature Secondary Structure 
GITVERLVNELKGVLPEDRVVINTTVRELHSKDESYHASSLPDVVVFPKTTEEVSTIMK
CEEHHHHHHHHHCCCCCCCEEEEHHHHHHHCCCCCCCCCCCCCEEEECCCHHHHHHHHH
IASEHGTPVVPFGVGSSLEGHVIPYEKGITVDFSLMNKILEIREKDFLVKVQPGVTRSQL
HHHHCCCEEEEECCCCCCCCCEEECCCCCEEEHHHHHHHHHHHCCCEEEEECCCCCHHHH
NKELKKYGLFFSVDPGADATLGGMAATNASGTTAVKYGVMRDQVRDLEVVLADGEVIHTG
HHHHHHHCCEEEECCCCCCCCCCEEECCCCCCHHEEHHHHHHHHCCEEEEEECCCEEECC
NLAAKSSSGYHLNGVFVGSEGTLGCFTELTLKVYGIPEHVMAARASFPAINDAVEAVINI
CCEECCCCCEEEEEEEECCCCCEEEHEEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHH
LQAGIPIARIELVDELSMKQVNHYSETSYREEPTLFLEFHGNEAGLKQDVEFTKEIVFDQ
HHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
KCKEVAFETETAARNKLWDARHNLAYAYVHSYPGKKLMSTDVCVPISELAGAIQQAKETL
HHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHHHH
EKNGLVGGILGHVGDGNFHVLLMVDPNDKEEVEKADEINESIVLYALKRGGTCTGEHGVG
HHCCCEEEHHHCCCCCCEEEEEEECCCCHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCC
IGKRKYQEEEHGAALFVMEKIKKALDPQNILNPNKVFQLKDRS
CCHHHCCHHHCCCCHHHHHHHHHHCCHHHCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-lactate; ferricytochrome c

Specific reaction: (R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]