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The map label for this gene is schC [H]

Identifier: 118478764

GI number: 118478764

Start: 3335466

End: 3337100

Strand: Reverse

Name: schC [H]

Synonym: BALH_3156

Alternate gene names: 118478764

Gene position: 3337100-3335466 (Counterclockwise)

Preceding gene: 118478769

Following gene: 118478763

Centisome position: 63.48

GC content: 37.06

Gene sequence:

>1635_bases
GTGGAGGATAAATATATGGAATCGAATGATGTACCAGTTTTAATTGTTGGAGGGGGATTATCAGGATTAGCATCTGCGTT
ATTCCTTGCAAAACATAATATTGAGTACTTGCTTATTGAGAGGCATCCGTCTACTGCAATTCATCCAAAAGCAGGTGGGA
TTACTTTCCGTACGATGGAGTTATTTCGAGAATTAGGTTTAGAACAAAGAATTAGATCGGCGGGTAAAGCATTAGAAAAT
TGCCGTGGAAGAATAGCAGTTCATACAATAGCTGAGGCGAATCAGGAAGAATTGGCACAAATGCGGGCGACTCAGTATGG
AAATGATGAAAAGTTACTTCAAAAAATAGAAGAGATTAGTCCATCAAAACAAACGGCTTGTTATCAAATTACTTTAGAAG
AGATGATGTTACTAGAGGCAAAAACATTAGGTGGGCAACTATCTTTTTATCATGAGTTAGTTTCATTTGAACAAAAGGAA
AACGGAGTAATAGCAACGATTCTAGATCGCGAAACGGAAAAAGAGAGCGTTGTTCATTGTGACTACGTAATTGCAGCAGA
TGGGGCAAAAAGTAAAATACGTGAGCAACTAAGGATAAGTACGGAGGGAAGAGGTACAATCGGTGGCTATTATATGAATA
TTTATTTTGAAGCGGATTTAAGTGAGTTTATACAAGGAGATGCATTTGGTTTTACTATGGTACTTCATCCTGAAGTTCTT
GGTGCGCTTATTCCAGTTGATAACGAAAGAAGATGGATTTACCATGTATCCTACGATCCGTTAAAAGGAGAGCGACCAGA
GGATTTCACTATAGAACGTTGTAAACAAATTATTCAAACAGCAATTGGAAGTACAAAAGTTGAGTCAGAAATAGTAAGTG
TTTTACCGTGGGAAGCGACTGAAAGTACTGCTACAAAATTTCAAGATAATCGCATTTTTTTAGTTGGTGATTCTGCACAT
ATTATGCCGCCAACAGGAGGGTTTGGTTCTAATACAGGAATACAAGATGTACACAATCTAGCCTGGAAATTAGCAGCTGT
TATAAAAGGAAAGGCAAAACCAAAACTGTTAGAAACATATCATGAAGAGAGATATCCTGTTGCAAAATTAACGACAGAGT
ATGCGAGTAGTTTGTTGTTCCGTGCTGCGAATAGAGAGGAAGGCAGTTTGAATAATACGGATGGTTTAGCTGTTACAGTT
GGATATCAGTATTGTTCAGAGGCGATTATAGATGACTCAGTCACTCCACATAGAATGGATAGCGTAAAGTTGAACGGGAG
ACCTGGAACGCGAGCGCCACACTTTTTTGGAACATATGATGGGAAAGAAATTTCAATACTTGATTTATTAGGTAACGATT
TTGTATTACTTACTATAGCAGAAAATCGTACTTGGGCTGAGTGTGTACAGAATGTTTCATCTACATTAGGAATAAATATA
AAATTTTATAGCGTTGGTTTAAGGGGAGACTTTATTGCTCAAGAAGATATTTTTAGCAAATTATATGGAATAGAGAATGG
AGGAGCTGTATTAATTAGACCAGATGGTTTTATAGGATGGCGCTCGGAAAAAGAGGTAGTAAATCTAGATGTAGTGCTTG
AAGAGGTAATGGGTAATTTATTATGTGATTTTTAA

Upstream 100 bases:

>100_bases
GGGGCGTAATCTATCTATATGATAATTTAAAATGAAATATAAGTCTATATCTTTGTTGTTTTTTTGATTATATTTATGTC
ACTGAGCTCAGAACAATGAT

Downstream 100 bases:

>100_bases
GTAACTAAGGAAGTATTGTCTTTTATAGGACGATACTTCTATTTTTTTAGTTTAAAAAATAAAGATTGTGTAGTGAAGAG
ACATTATTATTATAAAAATA

Product: PheA/TfdB family FAD-binding monooxygenase

Products: H2O; 3-(2,3-dihydroxyphenyl)propionate; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 544; Mature: 544

Protein sequence:

>544_residues
MEDKYMESNDVPVLIVGGGLSGLASALFLAKHNIEYLLIERHPSTAIHPKAGGITFRTMELFRELGLEQRIRSAGKALEN
CRGRIAVHTIAEANQEELAQMRATQYGNDEKLLQKIEEISPSKQTACYQITLEEMMLLEAKTLGGQLSFYHELVSFEQKE
NGVIATILDRETEKESVVHCDYVIAADGAKSKIREQLRISTEGRGTIGGYYMNIYFEADLSEFIQGDAFGFTMVLHPEVL
GALIPVDNERRWIYHVSYDPLKGERPEDFTIERCKQIIQTAIGSTKVESEIVSVLPWEATESTATKFQDNRIFLVGDSAH
IMPPTGGFGSNTGIQDVHNLAWKLAAVIKGKAKPKLLETYHEERYPVAKLTTEYASSLLFRAANREEGSLNNTDGLAVTV
GYQYCSEAIIDDSVTPHRMDSVKLNGRPGTRAPHFFGTYDGKEISILDLLGNDFVLLTIAENRTWAECVQNVSSTLGINI
KFYSVGLRGDFIAQEDIFSKLYGIENGGAVLIRPDGFIGWRSEKEVVNLDVVLEEVMGNLLCDF

Sequences:

>Translated_544_residues
MEDKYMESNDVPVLIVGGGLSGLASALFLAKHNIEYLLIERHPSTAIHPKAGGITFRTMELFRELGLEQRIRSAGKALEN
CRGRIAVHTIAEANQEELAQMRATQYGNDEKLLQKIEEISPSKQTACYQITLEEMMLLEAKTLGGQLSFYHELVSFEQKE
NGVIATILDRETEKESVVHCDYVIAADGAKSKIREQLRISTEGRGTIGGYYMNIYFEADLSEFIQGDAFGFTMVLHPEVL
GALIPVDNERRWIYHVSYDPLKGERPEDFTIERCKQIIQTAIGSTKVESEIVSVLPWEATESTATKFQDNRIFLVGDSAH
IMPPTGGFGSNTGIQDVHNLAWKLAAVIKGKAKPKLLETYHEERYPVAKLTTEYASSLLFRAANREEGSLNNTDGLAVTV
GYQYCSEAIIDDSVTPHRMDSVKLNGRPGTRAPHFFGTYDGKEISILDLLGNDFVLLTIAENRTWAECVQNVSSTLGINI
KFYSVGLRGDFIAQEDIFSKLYGIENGGAVLIRPDGFIGWRSEKEVVNLDVVLEEVMGNLLCDF
>Mature_544_residues
MEDKYMESNDVPVLIVGGGLSGLASALFLAKHNIEYLLIERHPSTAIHPKAGGITFRTMELFRELGLEQRIRSAGKALEN
CRGRIAVHTIAEANQEELAQMRATQYGNDEKLLQKIEEISPSKQTACYQITLEEMMLLEAKTLGGQLSFYHELVSFEQKE
NGVIATILDRETEKESVVHCDYVIAADGAKSKIREQLRISTEGRGTIGGYYMNIYFEADLSEFIQGDAFGFTMVLHPEVL
GALIPVDNERRWIYHVSYDPLKGERPEDFTIERCKQIIQTAIGSTKVESEIVSVLPWEATESTATKFQDNRIFLVGDSAH
IMPPTGGFGSNTGIQDVHNLAWKLAAVIKGKAKPKLLETYHEERYPVAKLTTEYASSLLFRAANREEGSLNNTDGLAVTV
GYQYCSEAIIDDSVTPHRMDSVKLNGRPGTRAPHFFGTYDGKEISILDLLGNDFVLLTIAENRTWAECVQNVSSTLGINI
KFYSVGLRGDFIAQEDIFSKLYGIENGGAVLIRPDGFIGWRSEKEVVNLDVVLEEVMGNLLCDF

Specific function: Involved in developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics which is essential for spore color in Streptomyces halstedii [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=550, Percent_Identity=22.3636363636364, Blast_Score=102, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.- [C]

Molecular weight: Translated: 60585; Mature: 60585

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDKYMESNDVPVLIVGGGLSGLASALFLAKHNIEYLLIERHPSTAIHPKAGGITFRTME
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEHHHHH
LFRELGLEQRIRSAGKALENCRGRIAVHTIAEANQEELAQMRATQYGNDEKLLQKIEEIS
HHHHCCHHHHHHHHHHHHHHCCCCEEEEEEHHCCHHHHHHHHHHCCCCHHHHHHHHHHCC
PSKQTACYQITLEEMMLLEAKTLGGQLSFYHELVSFEQKENGVIATILDRETEKESVVHC
CCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEE
DYVIAADGAKSKIREQLRISTEGRGTIGGYYMNIYFEADLSEFIQGDAFGFTMVLHPEVL
EEEEECCCCHHHHHHHHEECCCCCCCCCEEEEEEEEECCHHHHHCCCCCEEEEEECHHHH
GALIPVDNERRWIYHVSYDPLKGERPEDFTIERCKQIIQTAIGSTKVESEIVSVLPWEAT
HEECCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
ESTATKFQDNRIFLVGDSAHIMPPTGGFGSNTGIQDVHNLAWKLAAVIKGKAKPKLLETY
CHHHHEECCCEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
HEERYPVAKLTTEYASSLLFRAANREEGSLNNTDGLAVTVGYQYCSEAIIDDSVTPHRMD
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCCCC
SVKLNGRPGTRAPHFFGTYDGKEISILDLLGNDFVLLTIAENRTWAECVQNVSSTLGINI
EEEECCCCCCCCCCEEECCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHEEEE
KFYSVGLRGDFIAQEDIFSKLYGIENGGAVLIRPDGFIGWRSEKEVVNLDVVLEEVMGNL
EEEEEECCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHH
LCDF
HCCC
>Mature Secondary Structure
MEDKYMESNDVPVLIVGGGLSGLASALFLAKHNIEYLLIERHPSTAIHPKAGGITFRTME
CCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEHHHHH
LFRELGLEQRIRSAGKALENCRGRIAVHTIAEANQEELAQMRATQYGNDEKLLQKIEEIS
HHHHCCHHHHHHHHHHHHHHCCCCEEEEEEHHCCHHHHHHHHHHCCCCHHHHHHHHHHCC
PSKQTACYQITLEEMMLLEAKTLGGQLSFYHELVSFEQKENGVIATILDRETEKESVVHC
CCCCCEEEEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEE
DYVIAADGAKSKIREQLRISTEGRGTIGGYYMNIYFEADLSEFIQGDAFGFTMVLHPEVL
EEEEECCCCHHHHHHHHEECCCCCCCCCEEEEEEEEECCHHHHHCCCCCEEEEEECHHHH
GALIPVDNERRWIYHVSYDPLKGERPEDFTIERCKQIIQTAIGSTKVESEIVSVLPWEAT
HEECCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCC
ESTATKFQDNRIFLVGDSAHIMPPTGGFGSNTGIQDVHNLAWKLAAVIKGKAKPKLLETY
CHHHHEECCCEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHH
HEERYPVAKLTTEYASSLLFRAANREEGSLNNTDGLAVTVGYQYCSEAIIDDSVTPHRMD
HHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCCCC
SVKLNGRPGTRAPHFFGTYDGKEISILDLLGNDFVLLTIAENRTWAECVQNVSSTLGINI
EEEECCCCCCCCCCEEECCCCCEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHEEEE
KFYSVGLRGDFIAQEDIFSKLYGIENGGAVLIRPDGFIGWRSEKEVVNLDVVLEEVMGNL
EEEEEECCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCEEHHHHHHHHHHHHH
LCDF
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-(3-hydroxyphenyl)propionate; NADH; O2 [C]

Specific reaction: 3-(3-hydroxyphenyl)propionate + NADH + O2 = H2O + 3-(2,3-dihydroxyphenyl)propionate + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8253693; 8344517 [H]