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The map label for this gene is gmuR [H]

Identifier: 118478675

GI number: 118478675

Start: 3248142

End: 3248885

Strand: Reverse

Name: gmuR [H]

Synonym: BALH_3061

Alternate gene names: 118478675

Gene position: 3248885-3248142 (Counterclockwise)

Preceding gene: 118478676

Following gene: 118478674

Centisome position: 61.8

GC content: 39.11

Gene sequence:

>744_bases
ATGGAAATGGCAAGCGGATCAACACAAGTAAAATACCTCGGCATTTACCAAAAAATGAAACAGCAAATTTTAGACGGTGA
ATATAAAATTAACGAAAAAATTCCAAGTAGCCCCGTCCTTGCTGAAGAATTTGGTGTTTCAGTTCTTACCATAAAAAAAG
CGCTGGATTTGTTAGTGAGAGACGGCTACATCATCCGCCGGCGCGGAAGTGGAACAGTCGTTCAAGATTGGCGTCAGCAG
GAAAAGTCACGAATGATTCAAACTTTAACAGGTACGAAAGCAGTTTACGGCAGTGAGGTAGAAAGTAAAATTATTGAGTT
TACAATTGTCGGTGCCGATGAAATCATTGCTGAAAAATTAGGTATTTCAGTAGGGGATTTTGTATATAAAATCATCCGCC
TCCGCATCATTCACAATATCCCAACGATTATGGAGCATACATGGATGCCTATTTCGGTCATACCGGGTGTTGAAGTTTCA
GTTTTAGAGGGATCGATCTACTCACACATTCACAATAAACTAGGTCTTGAAGTAGGAACATCCGTTGTTAGGGTCAAAGG
GGTTCGCCCAGATGATAATGAAAAGCAGTTTATGAACTTAACAAATCAAGATTTCCTAATGAGAGTTGAACAAGTGGCCT
ATTTAACGGATGGACGAACTTTTGAATACTCTTATGCTGATCACCTGCCAGAAACTTTTGAATTTGAAACAGTCATTACT
GCAAAAAGCTATAAAGAGGTATAA

Upstream 100 bases:

>100_bases
AAATCTTAGAAAACGGATTTGCTGCACCTTCACCTTCAGTTTACAAACTTGAGGCTTTAAACTTGAATGAATAGAAGAGG
GAATACAGCATAAAGGAGGT

Downstream 100 bases:

>100_bases
AAAATAGGTTGGGGTACGTATTCCCTCAACCTATTTTCTGTCTTTAATATGGTAGGAATAATTATTATTCAGCTGTAATA
AGCATGGACGTATTCCTGTT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: Glucomannan utilization operon repressor; Glucomannan utilization protein R [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MEMASGSTQVKYLGIYQKMKQQILDGEYKINEKIPSSPVLAEEFGVSVLTIKKALDLLVRDGYIIRRRGSGTVVQDWRQQ
EKSRMIQTLTGTKAVYGSEVESKIIEFTIVGADEIIAEKLGISVGDFVYKIIRLRIIHNIPTIMEHTWMPISVIPGVEVS
VLEGSIYSHIHNKLGLEVGTSVVRVKGVRPDDNEKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVIT
AKSYKEV

Sequences:

>Translated_247_residues
MEMASGSTQVKYLGIYQKMKQQILDGEYKINEKIPSSPVLAEEFGVSVLTIKKALDLLVRDGYIIRRRGSGTVVQDWRQQ
EKSRMIQTLTGTKAVYGSEVESKIIEFTIVGADEIIAEKLGISVGDFVYKIIRLRIIHNIPTIMEHTWMPISVIPGVEVS
VLEGSIYSHIHNKLGLEVGTSVVRVKGVRPDDNEKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVIT
AKSYKEV
>Mature_247_residues
MEMASGSTQVKYLGIYQKMKQQILDGEYKINEKIPSSPVLAEEFGVSVLTIKKALDLLVRDGYIIRRRGSGTVVQDWRQQ
EKSRMIQTLTGTKAVYGSEVESKIIEFTIVGADEIIAEKLGISVGDFVYKIIRLRIIHNIPTIMEHTWMPISVIPGVEVS
VLEGSIYSHIHNKLGLEVGTSVVRVKGVRPDDNEKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVIT
AKSYKEV

Specific function: Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790118, Length=218, Percent_Identity=30.7339449541284, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1786950, Length=234, Percent_Identity=26.4957264957265, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082252, Length=159, Percent_Identity=30.188679245283, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790540, Length=225, Percent_Identity=24.4444444444444, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 28028; Mature: 28028

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMASGSTQVKYLGIYQKMKQQILDGEYKINEKIPSSPVLAEEFGVSVLTIKKALDLLVR
CCCCCCCCEEEHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHH
DGYIIRRRGSGTVVQDWRQQEKSRMIQTLTGTKAVYGSEVESKIIEFTIVGADEIIAEKL
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCEEEEEEEECHHHHHHHHH
GISVGDFVYKIIRLRIIHNIPTIMEHTWMPISVIPGVEVSVLEGSIYSHIHNKLGLEVGT
CCCHHHHHHHHHHHHHHHCCHHHHHHCCCCEEECCCCEEEEECCHHHHHHHHHHCHHHCC
SVVRVKGVRPDDNEKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVIT
EEEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHEECCCEEEEEHHHCCCCCEEEEEEEE
AKSYKEV
CCCCCCC
>Mature Secondary Structure
MEMASGSTQVKYLGIYQKMKQQILDGEYKINEKIPSSPVLAEEFGVSVLTIKKALDLLVR
CCCCCCCCEEEHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHH
DGYIIRRRGSGTVVQDWRQQEKSRMIQTLTGTKAVYGSEVESKIIEFTIVGADEIIAEKL
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHCEEEEEEEECHHHHHHHHH
GISVGDFVYKIIRLRIIHNIPTIMEHTWMPISVIPGVEVSVLEGSIYSHIHNKLGLEVGT
CCCHHHHHHHHHHHHHHHCCHHHHHHCCCCEEECCCCEEEEECCHHHHHHHHHHCHHHCC
SVVRVKGVRPDDNEKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVIT
EEEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHEECCCEEEEEHHHCCCCCEEEEEEEE
AKSYKEV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]