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The map label for this gene is tkt [H]

Identifier: 118478666

GI number: 118478666

Start: 3236517

End: 3238538

Strand: Reverse

Name: tkt [H]

Synonym: BALH_3051

Alternate gene names: 118478666

Gene position: 3238538-3236517 (Counterclockwise)

Preceding gene: 118478667

Following gene: 162382778

Centisome position: 61.6

GC content: 39.81

Gene sequence:

>2022_bases
ATGAAAGCATGTAGGGGGACGATTACTATGACACAAAACATAAATCAATTAGCAGTGAATACAATTCGTACGTTATCAAT
TGATGCTATTAATGCGGCAAATTCAGGTCATCCAGGTCTTCCGATGGGAGCAGCGCCAATGGCTTATGCATTATGGGCGA
ATCATTTAAATCATAATCCTAATCATCCAAAATGGTTTAACCGTGATCGCTTCGTTTTATCGGCGGGACATGGATCTAGC
TTATTATATAGCCTACTTCATTTAGCTGGATATGACGTTTCAATTGATGACTTGAAAAACTTCAGAAAGTTAAATAGTAA
AACACCAGGACATCCTGAGTTTGGTCATACTTCTGGAGTTGAAGCGACGACAGGCCCGTTAGGACAAGGGATTGCCAATG
CTGTCGGAATGGCAATGGCAGAAGCGCATTTAGCAGCGAAGTTTAATAAGGATGGTCACTCTATTATAGATCACAATACG
TACGCTTTAGTCGGAGACGGTGATTTAATGGAAGGTGTCGCTTATGAAGCGATGTCAATGGCAGGACATATGAAACTTGG
CAAGTTAATTGTGCTGTATGATTCAAATGAAATTTCACTTGATGGTGAATTAAACATTGCTTTCTCTGAAGATATGCAGA
AAAGGGTAGAATCTGCACATTGGCAATATGTAAGAGTTGAAGATGGAAACGATGTTGATGCGATTACAAAAGCGATTCAA
TTAGCGAAAGATAATACGGACCAACCTACTCTTATAGAGATTAGAACCGTTATAGGTTACGGAAGTCCAAAAGTTGCTGG
AACGAACAAAGCACATGGTAACCCGCTTGGATTAGAAGAAGCGACAGCGACAAAACAAGTGTATGGTTGGCATTATGAAG
AAGACTTCTTTGTACCTGAAGAAGTAACAGCTCATTTTAATGAACTGAAACAAAAAGGTATTGAAAAAGAACATGGCTGG
AATGAGCAGTTCAACTTATACAGAGAGTCAAACCCTGCACTAGCAGATGAATTAGAAAAAGCAATTACAGGTGAAGTTTT
AATCGAAGCGAAAGACATTTTATCCTTCGATACTGAAAAAACGATTTCAACTCGTGTTGCAAGTGGGGAAGCTATTAATC
ATTATGTGAAATCGATTCCTTCTATTTTCGGTGGAAGTGCGGATCTTTCTCATTCTACGATGACAGATATAAAAGGTGAA
GCAGTGTATGCGGTAGAATCGTATGCTGGCCGAAATATATACTTCGGTGTACGTGAACATGCAATGGGCGCGGCAGCGAA
TGGACTGGCTCTTCATGGAGGAGTAAAACCGTTCGTGAGTACATTCTTTGTATTTAATGACTATCTTCGTCCATCTATTC
GACTGGCTGCATTGCAAAAGTTACCTGTTACGTACGTATTTACACATGATTCGATTGCTGTAGGAGAAGATGGTCCAACG
CATGAACCTATTGAACATTTAGCAGCTCTTCGTGCAATTCCTGGTTTAACAGTTATCCGCCCGTCAGATGCAAATGAAAC
AGCAAGTGCGTGGGCGTATGCTTTACAGCAAACGGATGGTCCAGTCGTTTTAGTACTTAGCCGTCAAAATTTACCGGTGT
TTCATGAAACGAAAGCGAACATAGAGAATCTTTCTAAAGGAGCTTACGTATTAACACAAACGAATGAAAATCCAGATGTG
ATTTTAATTGCAACAGGTTCTGAAGTATCCTTGGCTGCTAGTGCAAAAGTGAAACTAGAAGAAGACAATGTCTCTGTTCG
TATCGTTGCAATGCCAAGCTGGGAGTTATTCGATCACCAATCGAAAGAATATAAGGAATCAGTTCTTCCGTCTTCTGTAA
CGAAACGAGTATCTCTTGAGATGGGCGTATCTCTCGGTTGGGAACGTTATGTAGGACAAGAAGGGAACATATTATCAATT
GAAACATTTGGAGCTTCAGGAACTGGGGCTGAAGTCATGAATCTATTTGGATTTACGACAGAAAATGTTGTTCAAATTAC
AAAAAATGTATTAAATTCTTAA

Upstream 100 bases:

>100_bases
GTCTGGTTCATATGGTCCAGAGGCATCTAATGAATTATTGCAAGAAAGTGGATTTAAATGGTGGTTAGATCAAGAAACGA
AAAAATAAGTACTTTCTTTC

Downstream 100 bases:

>100_bases
GCTATGACTGTGAATACCTTTCCGTACATATCAGTGCTGCAAGGTATTCCAGATTGTAGTGATATGAATTTGTAATAAAA
GATGATTTGAGGAGGAATTA

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 673; Mature: 673

Protein sequence:

>673_residues
MKACRGTITMTQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRDRFVLSAGHGSS
LLYSLLHLAGYDVSIDDLKNFRKLNSKTPGHPEFGHTSGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKDGHSIIDHNT
YALVGDGDLMEGVAYEAMSMAGHMKLGKLIVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYVRVEDGNDVDAITKAIQ
LAKDNTDQPTLIEIRTVIGYGSPKVAGTNKAHGNPLGLEEATATKQVYGWHYEEDFFVPEEVTAHFNELKQKGIEKEHGW
NEQFNLYRESNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASGEAINHYVKSIPSIFGGSADLSHSTMTDIKGE
AVYAVESYAGRNIYFGVREHAMGAAANGLALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPT
HEPIEHLAALRAIPGLTVIRPSDANETASAWAYALQQTDGPVVLVLSRQNLPVFHETKANIENLSKGAYVLTQTNENPDV
ILIATGSEVSLAASAKVKLEEDNVSVRIVAMPSWELFDHQSKEYKESVLPSSVTKRVSLEMGVSLGWERYVGQEGNILSI
ETFGASGTGAEVMNLFGFTTENVVQITKNVLNS

Sequences:

>Translated_673_residues
MKACRGTITMTQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRDRFVLSAGHGSS
LLYSLLHLAGYDVSIDDLKNFRKLNSKTPGHPEFGHTSGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKDGHSIIDHNT
YALVGDGDLMEGVAYEAMSMAGHMKLGKLIVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYVRVEDGNDVDAITKAIQ
LAKDNTDQPTLIEIRTVIGYGSPKVAGTNKAHGNPLGLEEATATKQVYGWHYEEDFFVPEEVTAHFNELKQKGIEKEHGW
NEQFNLYRESNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASGEAINHYVKSIPSIFGGSADLSHSTMTDIKGE
AVYAVESYAGRNIYFGVREHAMGAAANGLALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPT
HEPIEHLAALRAIPGLTVIRPSDANETASAWAYALQQTDGPVVLVLSRQNLPVFHETKANIENLSKGAYVLTQTNENPDV
ILIATGSEVSLAASAKVKLEEDNVSVRIVAMPSWELFDHQSKEYKESVLPSSVTKRVSLEMGVSLGWERYVGQEGNILSI
ETFGASGTGAEVMNLFGFTTENVVQITKNVLNS
>Mature_673_residues
MKACRGTITMTQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRDRFVLSAGHGSS
LLYSLLHLAGYDVSIDDLKNFRKLNSKTPGHPEFGHTSGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKDGHSIIDHNT
YALVGDGDLMEGVAYEAMSMAGHMKLGKLIVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYVRVEDGNDVDAITKAIQ
LAKDNTDQPTLIEIRTVIGYGSPKVAGTNKAHGNPLGLEEATATKQVYGWHYEEDFFVPEEVTAHFNELKQKGIEKEHGW
NEQFNLYRESNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASGEAINHYVKSIPSIFGGSADLSHSTMTDIKGE
AVYAVESYAGRNIYFGVREHAMGAAANGLALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPT
HEPIEHLAALRAIPGLTVIRPSDANETASAWAYALQQTDGPVVLVLSRQNLPVFHETKANIENLSKGAYVLTQTNENPDV
ILIATGSEVSLAASAKVKLEEDNVSVRIVAMPSWELFDHQSKEYKESVLPSSVTKRVSLEMGVSLGWERYVGQEGNILSI
ETFGASGTGAEVMNLFGFTTENVVQITKNVLNS

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=670, Percent_Identity=26.2686567164179, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI4507521, Length=670, Percent_Identity=26.2686567164179, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI133778974, Length=662, Percent_Identity=25.6797583081571, Blast_Score=162, Evalue=1e-39,
Organism=Homo sapiens, GI225637459, Length=686, Percent_Identity=22.0116618075802, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI225637463, Length=594, Percent_Identity=22.0538720538721, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI225637461, Length=596, Percent_Identity=22.3154362416107, Blast_Score=124, Evalue=3e-28,
Organism=Escherichia coli, GI48994911, Length=658, Percent_Identity=48.1762917933131, Blast_Score=636, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=666, Percent_Identity=47.4474474474475, Blast_Score=624, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI17539652, Length=660, Percent_Identity=25.4545454545455, Blast_Score=169, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6325331, Length=674, Percent_Identity=46.2908011869436, Blast_Score=583, Evalue=1e-167,
Organism=Saccharomyces cerevisiae, GI6319593, Length=672, Percent_Identity=44.1964285714286, Blast_Score=551, Evalue=1e-158,
Organism=Drosophila melanogaster, GI45551847, Length=673, Percent_Identity=27.9346210995542, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI45550715, Length=673, Percent_Identity=27.9346210995542, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24645119, Length=633, Percent_Identity=27.6461295418641, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24666278, Length=672, Percent_Identity=26.1904761904762, Blast_Score=184, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 73188; Mature: 73188

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKACRGTITMTQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNP
CCCCCCCEEEECCCHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCC
NHPKWFNRDRFVLSAGHGSSLLYSLLHLAGYDVSIDDLKNFRKLNSKTPGHPEFGHTSGV
CCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
EATTGPLGQGIANAVGMAMAEAHLAAKFNKDGHSIIDHNTYALVGDGDLMEGVAYEAMSM
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCHHHHHHHHHHHHH
AGHMKLGKLIVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYVRVEDGNDVDAITKAIQ
HCCEEECCEEEEECCCEEEECCEEEEEEHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHH
LAKDNTDQPTLIEIRTVIGYGSPKVAGTNKAHGNPLGLEEATATKQVYGWHYEEDFFVPE
HHCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEECCCCCCCHH
EVTAHFNELKQKGIEKEHGWNEQFNLYRESNPALADELEKAITGEVLIEAKDILSFDTEK
HHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEHHHHCCCCCH
TISTRVASGEAINHYVKSIPSIFGGSADLSHSTMTDIKGEAVYAVESYAGRNIYFGVREH
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEEECCCCCEEEEEEHHH
AMGAAANGLALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPT
HCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCEEECCCCCC
HEPIEHLAALRAIPGLTVIRPSDANETASAWAYALQQTDGPVVLVLSRQNLPVFHETKAN
HHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCC
IENLSKGAYVLTQTNENPDVILIATGSEVSLAASAKVKLEEDNVSVRIVAMPSWELFDHQ
HHHCCCCEEEEEECCCCCCEEEEECCCCEEEEEEEEEEEECCCEEEEEEEECCHHHHCCC
SKEYKESVLPSSVTKRVSLEMGVSLGWERYVGQEGNILSIETFGASGTGAEVMNLFGFTT
CHHHHHHCCCHHHHHHEEEECCCCCCHHHHCCCCCCEEEEEECCCCCCCHHHHHHHCCCH
ENVVQITKNVLNS
HHHHHHHHHHHCC
>Mature Secondary Structure
MKACRGTITMTQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNP
CCCCCCCEEEECCCHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCC
NHPKWFNRDRFVLSAGHGSSLLYSLLHLAGYDVSIDDLKNFRKLNSKTPGHPEFGHTSGV
CCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCC
EATTGPLGQGIANAVGMAMAEAHLAAKFNKDGHSIIDHNTYALVGDGDLMEGVAYEAMSM
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCHHHHHHHHHHHHH
AGHMKLGKLIVLYDSNEISLDGELNIAFSEDMQKRVESAHWQYVRVEDGNDVDAITKAIQ
HCCEEECCEEEEECCCEEEECCEEEEEEHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHH
LAKDNTDQPTLIEIRTVIGYGSPKVAGTNKAHGNPLGLEEATATKQVYGWHYEEDFFVPE
HHCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEECCCCCCCHH
EVTAHFNELKQKGIEKEHGWNEQFNLYRESNPALADELEKAITGEVLIEAKDILSFDTEK
HHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEHHHHCCCCCH
TISTRVASGEAINHYVKSIPSIFGGSADLSHSTMTDIKGEAVYAVESYAGRNIYFGVREH
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEEECCCCCEEEEEEHHH
AMGAAANGLALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPT
HCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCEEECCCCCC
HEPIEHLAALRAIPGLTVIRPSDANETASAWAYALQQTDGPVVLVLSRQNLPVFHETKAN
HHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCEEECCCCC
IENLSKGAYVLTQTNENPDVILIATGSEVSLAASAKVKLEEDNVSVRIVAMPSWELFDHQ
HHHCCCCEEEEEECCCCCCEEEEECCCCEEEEEEEEEEEECCCEEEEEEEECCHHHHCCC
SKEYKESVLPSSVTKRVSLEMGVSLGWERYVGQEGNILSIETFGASGTGAEVMNLFGFTT
CHHHHHHCCCHHHHHHEEEECCCCCCHHHHCCCCCCEEEEEECCCCCCCHHHHHHHCCCH
ENVVQITKNVLNS
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]