Click here to switch to the map view.

The map label for this gene is gntK [H]

Identifier: 118478662

GI number: 118478662

Start: 3231486

End: 3233027

Strand: Reverse

Name: gntK [H]

Synonym: BALH_3046

Alternate gene names: 118478662

Gene position: 3233027-3231486 (Counterclockwise)

Preceding gene: 118478663

Following gene: 118478661

Centisome position: 61.5

GC content: 37.94

Gene sequence:

>1542_bases
ATGGTGAGTTCAAAATATATGATTGGTGTAGACATTGGGACAACTAGTACAAAATCAGTTCTATTTTCTACAGATGGATC
TGTTATTGCAAGTCATGGAATTGAATATCCTTTATATTCTCCTACGCCGGAAACAGCAGAACAAGACCCAGAAGAAATTT
TTCGTGCAGTAATACATACGATTAAAGAAACTGTACAGACAAGTAGTGTACAGCCGCATGATATTCTTTGTGTTTCTTTT
AGTTCGGCAATGCATAGTATCATTGCTGTAGATGAGAAGGGAAAGCCGTTAACGAGATGTATTACTTGGGCAGATAATAG
AAGTGCAAGCTGGGCAGAGAAAATAAAGAATGATATGAATGGTCATGAAATTTATTTACGGACTGGGACACCAATTCATC
CGATGTCACCACTTTCGAAATTAGTTTGGCTACAAAATGAGCAGGCAGAATTGTTCGCAAAAACTTATAAATTTATTTCT
ATTAAAGAGTATGTTTTTTATAAGTTATATAAGGAGTATGTAATTGATTATTCTATAGCATCAGCAACAGGGATGTTTAA
TTTGAAATCTTTAAAATGGGATGAAGAGGCTTTACATGTTGCGGGAATTACAGATGATAAACTTTCTAAACTCGTTCCAA
CAACGCACAGTTTAACAGGATTAGATGAAGAGCTTGCCAATGAGATGAATGTACTTGTTTCTACTCCATTTGTAGTAGGA
GCGAGTGACGGAGTCCTATCCAATTTAGGTGTAAATGCAATTGATCCTGGTGTTGTGGCTGTTACAATTGGTACAAGCGG
TGCGATACGTGCTGTAACAAATCGACCTGTAACTGATCCGAAAGGTAGAATTTTTTGTTACGCCCTAACTGAAGACCATT
GGGTAATTGGCGGACCAGTTAATAACGGTGGTATGATTTTCAGGTGGGCTCGTGATCAATTAGGTACTTCAGAGATTGAA
CTTGCGAAGCGCTTAGGAAAAGATCCATATGAAGTGCTTACTGAAATAGCAGCAAAAGTGAATCCGGGATCTGATGGGTT
ATTATTTCACCCGTATTTAGCAGGAGAAAGAGCTCCTTTATGGAATGCAAATGCGCGAGGATCATTCTTTGGACTTGGAT
TGCACCATAAGAAAGAACATCTGATTCGTGCAGTTTTAGAAGGGGTAATTTATAACTTATATACCGTTCTTCTCGCTTTA
AAAGAACTCATTGGCGAACCGAAAAAAATTCAAGCGACAGGCGGTTTTGCAAGATCGGAACTTTGGAGACAGATGATGGC
GGATATTTTTCACCAAGACGTATATGTTCCCGAAAGTTTCGAAAGCTCTTGCTTAGGAGCTGCCATACTCGGCTTATATA
GTTTAGGTGAAGTAGATACGTTACATGTAGTTTCTGAAATGGTAGGTGCGAATTTCCACCATGAACCAAACATGGAAAGT
GTGGAAAAATATAAAGATTTAACACCAATCTATATTCGTCTGTCCCGTCAATTGGAAGAAGAATATGAAAGTATAGCAGA
TTATCAAAAAAAGTGGGTTTAA

Upstream 100 bases:

>100_bases
TTTATCGCTTTTGGAGGAGTTTTACTACTCGATATGTTTATTTAAAATAAGGATGTTTTTATGGTGGGATACTGTAGTAA
TTTTTTGTTAGGAGGAAGAA

Downstream 100 bases:

>100_bases
AGGCTATTTAGCAGAGAAATATGGTAACGTATAAAGAGGTACTCCAATTTTTTTGGATACTCTTTCAACATAAAATATGT
TAAGAAGTATGATGAGCGAA

Product: gluconate kinase (2-dehydro-3-deoxygluconokinase)

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MVSSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHTIKETVQTSSVQPHDILCVSF
SSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMNGHEIYLRTGTPIHPMSPLSKLVWLQNEQAELFAKTYKFIS
IKEYVFYKLYKEYVIDYSIASATGMFNLKSLKWDEEALHVAGITDDKLSKLVPTTHSLTGLDEELANEMNVLVSTPFVVG
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEDHWVIGGPVNNGGMIFRWARDQLGTSEIE
LAKRLGKDPYEVLTEIAAKVNPGSDGLLFHPYLAGERAPLWNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLAL
KELIGEPKKIQATGGFARSELWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEVDTLHVVSEMVGANFHHEPNMES
VEKYKDLTPIYIRLSRQLEEEYESIADYQKKWV

Sequences:

>Translated_513_residues
MVSSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHTIKETVQTSSVQPHDILCVSF
SSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMNGHEIYLRTGTPIHPMSPLSKLVWLQNEQAELFAKTYKFIS
IKEYVFYKLYKEYVIDYSIASATGMFNLKSLKWDEEALHVAGITDDKLSKLVPTTHSLTGLDEELANEMNVLVSTPFVVG
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEDHWVIGGPVNNGGMIFRWARDQLGTSEIE
LAKRLGKDPYEVLTEIAAKVNPGSDGLLFHPYLAGERAPLWNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLAL
KELIGEPKKIQATGGFARSELWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEVDTLHVVSEMVGANFHHEPNMES
VEKYKDLTPIYIRLSRQLEEEYESIADYQKKWV
>Mature_513_residues
MVSSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHTIKETVQTSSVQPHDILCVSF
SSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMNGHEIYLRTGTPIHPMSPLSKLVWLQNEQAELFAKTYKFIS
IKEYVFYKLYKEYVIDYSIASATGMFNLKSLKWDEEALHVAGITDDKLSKLVPTTHSLTGLDEELANEMNVLVSTPFVVG
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEDHWVIGGPVNNGGMIFRWARDQLGTSEIE
LAKRLGKDPYEVLTEIAAKVNPGSDGLLFHPYLAGERAPLWNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLAL
KELIGEPKKIQATGGFARSELWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEVDTLHVVSEMVGANFHHEPNMES
VEKYKDLTPIYIRLSRQLEEEYESIADYQKKWV

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI189409120, Length=462, Percent_Identity=26.8398268398268, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI42794763, Length=463, Percent_Identity=25.9179265658747, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI4504007, Length=463, Percent_Identity=26.7818574514039, Blast_Score=123, Evalue=5e-28,
Organism=Homo sapiens, GI88196792, Length=483, Percent_Identity=25.879917184265, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI41393575, Length=453, Percent_Identity=26.2693156732892, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1789987, Length=494, Percent_Identity=27.3279352226721, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1787789, Length=502, Percent_Identity=28.6852589641434, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1790361, Length=501, Percent_Identity=26.5469061876248, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1790005, Length=494, Percent_Identity=22.8744939271255, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789168, Length=394, Percent_Identity=23.6040609137056, Blast_Score=102, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17535599, Length=459, Percent_Identity=24.8366013071895, Blast_Score=121, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321755, Length=536, Percent_Identity=25.1865671641791, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24655555, Length=470, Percent_Identity=24.8936170212766, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24655560, Length=470, Percent_Identity=24.8936170212766, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24655570, Length=470, Percent_Identity=24.8936170212766, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24655574, Length=470, Percent_Identity=24.8936170212766, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24655565, Length=470, Percent_Identity=24.8936170212766, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24656367, Length=554, Percent_Identity=22.5631768953069, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI21357867, Length=567, Percent_Identity=22.0458553791887, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI17864214, Length=479, Percent_Identity=24.2171189979123, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24654573, Length=423, Percent_Identity=23.6406619385343, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24657106, Length=568, Percent_Identity=23.4154929577465, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24657102, Length=568, Percent_Identity=23.4154929577465, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24656372, Length=366, Percent_Identity=21.8579234972678, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 56966; Mature: 56966

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHT
CCCCCEEEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IKETVQTSSVQPHDILCVSFSSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMN
HHHHHHHCCCCCCEEEEEEHHHHHHHEEEECCCCCCHHHEEEECCCCCHHHHHHHHCCCC
GHEIYLRTGTPIHPMSPLSKLVWLQNEQAELFAKTYKFISIKEYVFYKLYKEYVIDYSIA
CCEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SATGMFNLKSLKWDEEALHVAGITDDKLSKLVPTTHSLTGLDEELANEMNVLVSTPFVVG
HHCCCEEECCCCCCCHHEEEECCCHHHHHHHCCCCCHHCCCHHHHHHHHHEEEECCEEEE
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEDHWVIGGPV
CCCCHHHHCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCEEEECEE
NNGGMIFRWARDQLGTSEIELAKRLGKDPYEVLTEIAAKVNPGSDGLLFHPYLAGERAPL
CCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCC
WNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLALKELIGEPKKIQATGGFARSE
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH
LWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEVDTLHVVSEMVGANFHHEPNMES
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHH
VEKYKDLTPIYIRLSRQLEEEYESIADYQKKWV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHT
CCCCCEEEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IKETVQTSSVQPHDILCVSFSSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMN
HHHHHHHCCCCCCEEEEEEHHHHHHHEEEECCCCCCHHHEEEECCCCCHHHHHHHHCCCC
GHEIYLRTGTPIHPMSPLSKLVWLQNEQAELFAKTYKFISIKEYVFYKLYKEYVIDYSIA
CCEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SATGMFNLKSLKWDEEALHVAGITDDKLSKLVPTTHSLTGLDEELANEMNVLVSTPFVVG
HHCCCEEECCCCCCCHHEEEECCCHHHHHHHCCCCCHHCCCHHHHHHHHHEEEECCEEEE
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEDHWVIGGPV
CCCCHHHHCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCEEEECEE
NNGGMIFRWARDQLGTSEIELAKRLGKDPYEVLTEIAAKVNPGSDGLLFHPYLAGERAPL
CCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCC
WNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLALKELIGEPKKIQATGGFARSE
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH
LWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEVDTLHVVSEMVGANFHHEPNMES
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHH
VEKYKDLTPIYIRLSRQLEEEYESIADYQKKWV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377 [H]