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The map label for this gene is yyaH [H]

Identifier: 118478643

GI number: 118478643

Start: 3213603

End: 3214013

Strand: Reverse

Name: yyaH [H]

Synonym: BALH_3024

Alternate gene names: 118478643

Gene position: 3214013-3213603 (Counterclockwise)

Preceding gene: 118478644

Following gene: 118478640

Centisome position: 61.14

GC content: 34.31

Gene sequence:

>411_bases
TTGAATAACATAAAAGAAAAGGTGTCGTTTATGAAAATTGAACATGTAGCAATTTGGGTGAATGATTTAGAAGAAATGCG
TGATTTCTATAAACAGTATTTTAACGGTGAAGAAAATAGCTTATATCACAATCCGAAAAAGCAGTTTGAATCTTATTTCA
TAACTTTTGAAGGCGGTGCGCGTCTAGAACTTATGAAGCAGGTAGGAATAGATGATAATACACAAACACAGACAATAGGA
TATGCGCATATTGCTTTTTCTGTAGGTAGTAAAGAAAAAGTGAACGAATTAACAAATACATTAAGAGAAGCAGGGTATCC
TGTGTTAAACGGCCCACGAACTACAGGGGATGGTTACTATGAAAGTGTAGTAAGTGATCCTGAAGGAAATCAGATTGAGA
TAACAATCTAA

Upstream 100 bases:

>100_bases
GATTATTTATATGGATTAAAAAGTCTAGGACTTGATCTTATGATTACGAGAACGAATAAAGAAAATTAAATGTGCTGGCA
ATGAAGCATTCAATTGTCAG

Downstream 100 bases:

>100_bases
CATTTTGTTTACGGTAAGCGATAAAAACCTCATTTCGCGTTGTAATGACGAGAAATGAGGTTTTTATATTACTATATAAA
ATGAAAGGAAGATCCATTTT

Product: glyoxylase family protein (lactoylglutathione lyase)

Products: glutathione; methylglyoxal

Alternate protein names: ORFF [H]

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MNNIKEKVSFMKIEHVAIWVNDLEEMRDFYKQYFNGEENSLYHNPKKQFESYFITFEGGARLELMKQVGIDDNTQTQTIG
YAHIAFSVGSKEKVNELTNTLREAGYPVLNGPRTTGDGYYESVVSDPEGNQIEITI

Sequences:

>Translated_136_residues
MNNIKEKVSFMKIEHVAIWVNDLEEMRDFYKQYFNGEENSLYHNPKKQFESYFITFEGGARLELMKQVGIDDNTQTQTIG
YAHIAFSVGSKEKVNELTNTLREAGYPVLNGPRTTGDGYYESVVSDPEGNQIEITI
>Mature_136_residues
MNNIKEKVSFMKIEHVAIWVNDLEEMRDFYKQYFNGEENSLYHNPKKQFESYFITFEGGARLELMKQVGIDDNTQTQTIG
YAHIAFSVGSKEKVNELTNTLREAGYPVLNGPRTTGDGYYESVVSDPEGNQIEITI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: 4.4.1.5

Molecular weight: Translated: 15613; Mature: 15613

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIKEKVSFMKIEHVAIWVNDLEEMRDFYKQYFNGEENSLYHNPKKQFESYFITFEGGA
CCCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEECCCC
RLELMKQVGIDDNTQTQTIGYAHIAFSVGSKEKVNELTNTLREAGYPVLNGPRTTGDGYY
HHHHHHHCCCCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
ESVVSDPEGNQIEITI
HHHCCCCCCCEEEEEC
>Mature Secondary Structure
MNNIKEKVSFMKIEHVAIWVNDLEEMRDFYKQYFNGEENSLYHNPKKQFESYFITFEGGA
CCCHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEEEEECCCC
RLELMKQVGIDDNTQTQTIGYAHIAFSVGSKEKVNELTNTLREAGYPVLNGPRTTGDGYY
HHHHHHHCCCCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHH
ESVVSDPEGNQIEITI
HHHCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (R)-S-lactoylglutathione

Specific reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]