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The map label for this gene is ampC [C]

Identifier: 118478349

GI number: 118478349

Start: 2880521

End: 2881687

Strand: Reverse

Name: ampC [C]

Synonym: BALH_2713

Alternate gene names: 118478349

Gene position: 2881687-2880521 (Counterclockwise)

Preceding gene: 118478350

Following gene: 118478348

Centisome position: 54.82

GC content: 38.05

Gene sequence:

>1167_bases
ATGAAAAAACGTAATTCAATGAAGTTAGCAAGTTTGACAGTTTTATTAGCGGGTACTACTCTATTTACACCTGGTTTCAC
TGTGAAAGCAGAGTCTACTCAAAGTATTTCGAATTCGTCAAAAGTACATGATCAAAAGAATCGGAATGGATGGAAACAAG
TAATGCAGGAAACAATACAAATTGGGGCGCCGGGGGTATTAGCTAAGACATCTAATAAAGGAAAAATTAGTAGTTATACT
GCTGGCGTAGCAGATTTAAGTACTAAGAAACCGGTGAAATCGGATTATCGCTTTCGGATTGGTAGTGTGACGAAAACTTT
TACCGCCACGACTGTTCTTCAATTAGTAGGAGAAAATCGCGTACAACTGGACGATTCAATTGAAAAGTGGCTACCGGGTC
TCATTCAAGGAAATGGGTATGATGGTAATCAAATTACGATACGTCAACTTTTGAATCATACAAGTGGTATCGCTGAATAC
TTAAAGTCAAAAGATGCTGACATAATGAATTCGAAAAAAACGTATACAGCAGAAGAAATAGTGAAAATAGGACTTGCGCT
GCCTTCGGATTTTTCGCCAGGTAAAGGCTGGTCGTATTCAAACACAGGATATGTAATATTGGGAATGCTAATTGAAAAAA
TAACTGGTAATAGTTATGCGGAAGAAATCGAAAAGCGAATTATTGAACCTTTGGACTTGCCAAATACGTTTTTACCAGGT
AATTCACCTGTCATCCCAGGAAAGAATCATGCTCGTGGATATGTGAAAATGGAAGAAACAGGCGAGTTGAAAGACATTAC
GTATTATAATCCGAGTTTAGCTAATGCAGCTGGAGACATGATTTCTAATGCGGATGATTTAAACAAGTTCTTTTCATCTT
TACTCGGTGGTAAGTTACTGAAGGAACGCGAGCTAAAAGAAATGCTTACTACAGTTCCTGTAGAAGGAAAAGGGATTGGT
GATGGATATGGTCTTGGAATCTATGAGACTAAACTTCCAAATGGTGTCTCAGTATGGGGGCACGGAGGATCAATTCCTGG
GTTTATGACTTTTGCTGGTGGAGTAATTGGAGGCAAGCATACATTTGCTGTCAATGTTAACTCTTTAGGTCCAGTTGATA
TCCTTACACAGTTTGATAAAATGATGCAAGTTGAATTTAATAAATAG

Upstream 100 bases:

>100_bases
AGTATTTCGTAAGGAATGGATAAGAAAAAAGACAGTTTTATCATATAGGATGAAAGTATAGCTTGAATCAATACGATATG
AATAGGGGAGAGAAATCCTT

Downstream 100 bases:

>100_bases
ATGAAGAGAAAGCGAATGGGGTTCTGCAATAGTTGTAAATAAAAGAGATGCTTTTTAAATTTCACAAATAAGGACAGTAT
TAACATTCATGATATGGTAT

Product: alkaline D-peptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKKRNSMKLASLTVLLAGTTLFTPGFTVKAESTQSISNSSKVHDQKNRNGWKQVMQETIQIGAPGVLAKTSNKGKISSYT
AGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENRVQLDDSIEKWLPGLIQGNGYDGNQITIRQLLNHTSGIAEY
LKSKDADIMNSKKTYTAEEIVKIGLALPSDFSPGKGWSYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLPNTFLPG
NSPVIPGKNHARGYVKMEETGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLLKERELKEMLTTVPVEGKGIG
DGYGLGIYETKLPNGVSVWGHGGSIPGFMTFAGGVIGGKHTFAVNVNSLGPVDILTQFDKMMQVEFNK

Sequences:

>Translated_388_residues
MKKRNSMKLASLTVLLAGTTLFTPGFTVKAESTQSISNSSKVHDQKNRNGWKQVMQETIQIGAPGVLAKTSNKGKISSYT
AGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENRVQLDDSIEKWLPGLIQGNGYDGNQITIRQLLNHTSGIAEY
LKSKDADIMNSKKTYTAEEIVKIGLALPSDFSPGKGWSYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLPNTFLPG
NSPVIPGKNHARGYVKMEETGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLLKERELKEMLTTVPVEGKGIG
DGYGLGIYETKLPNGVSVWGHGGSIPGFMTFAGGVIGGKHTFAVNVNSLGPVDILTQFDKMMQVEFNK
>Mature_388_residues
MKKRNSMKLASLTVLLAGTTLFTPGFTVKAESTQSISNSSKVHDQKNRNGWKQVMQETIQIGAPGVLAKTSNKGKISSYT
AGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENRVQLDDSIEKWLPGLIQGNGYDGNQITIRQLLNHTSGIAEY
LKSKDADIMNSKKTYTAEEIVKIGLALPSDFSPGKGWSYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLPNTFLPG
NSPVIPGKNHARGYVKMEETGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLLKERELKEMLTTVPVEGKGIG
DGYGLGIYETKLPNGVSVWGHGGSIPGFMTFAGGVIGGKHTFAVNVNSLGPVDILTQFDKMMQVEFNK

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=303, Percent_Identity=25.4125412541254, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082101, Length=172, Percent_Identity=27.906976744186, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115533026, Length=401, Percent_Identity=26.4339152119701, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17550934, Length=309, Percent_Identity=26.8608414239482, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17565630, Length=293, Percent_Identity=26.962457337884, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 42118; Mature: 42118

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRNSMKLASLTVLLAGTTLFTPGFTVKAESTQSISNSSKVHDQKNRNGWKQVMQETIQ
CCCCCCCHHHHHHHHEECCEEECCCEEEEECCHHHHCCCHHHHHHHCCHHHHHHHHHHHH
IGAPGVLAKTSNKGKISSYTAGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENR
CCCCCEEEECCCCCCCCHHHCCHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCC
VQLDDSIEKWLPGLIQGNGYDGNQITIRQLLNHTSGIAEYLKSKDADIMNSKKTYTAEEI
EEECHHHHHHCCHHEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHH
VKIGLALPSDFSPGKGWSYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLPNTFLPG
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCC
NSPVIPGKNHARGYVKMEETGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLL
CCCCCCCCCCCCCEEEECCCCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCHHHH
KERELKEMLTTVPVEGKGIGDGYGLGIYETKLPNGVSVWGHGGSIPGFMTFAGGVIGGKH
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCCCHHHHHHCCCCCCCE
TFAVNVNSLGPVDILTQFDKMMQVEFNK
EEEEECCCCCCHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MKKRNSMKLASLTVLLAGTTLFTPGFTVKAESTQSISNSSKVHDQKNRNGWKQVMQETIQ
CCCCCCCHHHHHHHHEECCEEECCCEEEEECCHHHHCCCHHHHHHHCCHHHHHHHHHHHH
IGAPGVLAKTSNKGKISSYTAGVADLSTKKPVKSDYRFRIGSVTKTFTATTVLQLVGENR
CCCCCEEEECCCCCCCCHHHCCHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCC
VQLDDSIEKWLPGLIQGNGYDGNQITIRQLLNHTSGIAEYLKSKDADIMNSKKTYTAEEI
EEECHHHHHHCCHHEECCCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHH
VKIGLALPSDFSPGKGWSYSNTGYVILGMLIEKITGNSYAEEIEKRIIEPLDLPNTFLPG
HHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCC
NSPVIPGKNHARGYVKMEETGELKDITYYNPSLANAAGDMISNADDLNKFFSSLLGGKLL
CCCCCCCCCCCCCEEEECCCCCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCHHHH
KERELKEMLTTVPVEGKGIGDGYGLGIYETKLPNGVSVWGHGGSIPGFMTFAGGVIGGKH
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCCCHHHHHHCCCCCCCE
TFAVNVNSLGPVDILTQFDKMMQVEFNK
EEEEECCCCCCHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]