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The map label for this gene is phoA [H]

Identifier: 118478323

GI number: 118478323

Start: 2851391

End: 2853064

Strand: Reverse

Name: phoA [H]

Synonym: BALH_2686

Alternate gene names: 118478323

Gene position: 2853064-2851391 (Counterclockwise)

Preceding gene: 118478326

Following gene: 118478322

Centisome position: 54.27

GC content: 37.04

Gene sequence:

>1674_bases
ATGTCGGAGTTAGCTTTAAAGATGAAGAGATTACTGTTAGTAGGCACAATCATACTAAGTATGTTATGTACTGAAAATTT
GATGAATTATCATACAGTGGAAGCTAAAGTGAAAAAAGTAGAACGGAAGCCTAAAAATGTAATCATAATGGTTATGGACG
GCACAAGTTCTACAGCAACTACATTAGCTCGCTTGTATAAAGGGAAAGCACTTGCATTAGATGAAATTGTAACAGGAGGA
GTGCGTACATATTCGGCGGAATCAGCTATAACAGACTCAGCTCCAGCAGTTACAGCTTTAGCGACGGGGAATAAATCAAA
TTCAGGATATGTAGGCGTATTACCTTCAATTGTAAGTTCACCTGGCTTAAAACCAATGAAAGAAGAGGATAAGTTACGAC
CAGTTGCCAATGTTTTAGAAGGTGCAAAACGTACGGGTCGCGCAACTGGAATTGTTGCTACAGCTGAAATTCAGCATGCT
ACTCCTGCTGGATTCTCCGCTCATCATGTGAATCGTAACAATTTTGAAGTGCTCGCGGAGCAACAAGTATATCAAAATAT
AGATGTCGTATTAGGTGGGGGAAAAGCAGCACTTCTACCTGAGACAGATAGTGGGATTCGAAAAGACGGTGAAGATTTAG
TAAAAGTGATCAAAAACAAAGGTTACGACTTTGTTGAAACGAAAGAAGCATTATTAGGCTCTAAATCTAATAAAATTTGG
GGCTCTTTCTCGCTTAATGCTTTAGCATTTGATATGGATCGTGAAGCAACAAACCCAGAGCAACCAACACTTTCGCAAAT
GACGGAAAAAGCAATTCAAACGTTATCAAAAGATAAAGATGGCTTCTTTTTATTTGTGGAAGGAAGTAAGCCAGACTGGG
CAGCTCATGTGAATGATCCAATTGGGATGATTAGTGATGTATTAGCATTTGATAATGCAGTTGCAGAAGCATTGAAATTT
GCAAAAAAAGATGGTAATACGATGCTAATAGCCGTAGCGGACCATGGTAATAGCGGTATTTCTATTGGGAATATGAATAC
GACAAAAGGATATAATACTACGCCGGTCTCTGCGTACATTTATCCATTGAAAAAAGCGAAGATGACACTTGAAGGGACTA
TCAATAATTTGAAAGCTGATATATCCAATGTAGAAGAGGTAGCTAAATTATACGGGTTGGACAATTTAACTTATGATGAA
AAAGAAAGGTTAAAAACGGCTAAAAAGAAAATAGATGTAGGTCCAATTTTCACTACATTATTGTCTAAGCGTGCGAACAT
AGGCTTCACAACAGGAGGGCATACAGGTGAGGATGTATTCTTATATTCATACGGTCCTCAAAAGCCATACGGTTTGATTC
AAAATACGGACGTTGCGAAGACGATGGCGAAAGCGATGGGCTTTAACTTAGAAAAAGTAACAAACAAATTATTTGTAGAA
AGTGAATCAGCCTTTAAGCAGAATGGTGCAACTGTAACAATAGATAAAACTGATGTAGCGAACCCTGTACTCATAGTAAA
ACGTAATAATGTAACAGCTCAATTATTTGTTAACAAAAATATAATTCGTATTAAGAATAAAGAGTATGAATTAGGAAGTA
TTGTTGTAGAAAGTAATGGAAAGGTTTACGTACCAGAAGAAGCAATTCATCTATTTAGAAAACATTCTCGTTAA

Upstream 100 bases:

>100_bases
AGAAGAATTGGGAACTAATAAAACATATATAGGTTGTGAAAAGTAAAACGAAACCAGAACTTTGTATGTAAATGAATGAG
AAACAAATGGAGGCGCAATA

Downstream 100 bases:

>100_bases
AAGATTGCCAACCACTTACCTTAATTAGGAGGAGTGGTTGGCAATTTTTTGTTTATTAGACGTAAGCAATTTGTAAGGAG
TGAGTAAGAAAAAAGAGAAT

Product: alkaline phosphatase

Products: NA

Alternate protein names: Alkaline phosphatase IV; APase IV [H]

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MSELALKMKRLLLVGTIILSMLCTENLMNYHTVEAKVKKVERKPKNVIIMVMDGTSSTATTLARLYKGKALALDEIVTGG
VRTYSAESAITDSAPAVTALATGNKSNSGYVGVLPSIVSSPGLKPMKEEDKLRPVANVLEGAKRTGRATGIVATAEIQHA
TPAGFSAHHVNRNNFEVLAEQQVYQNIDVVLGGGKAALLPETDSGIRKDGEDLVKVIKNKGYDFVETKEALLGSKSNKIW
GSFSLNALAFDMDREATNPEQPTLSQMTEKAIQTLSKDKDGFFLFVEGSKPDWAAHVNDPIGMISDVLAFDNAVAEALKF
AKKDGNTMLIAVADHGNSGISIGNMNTTKGYNTTPVSAYIYPLKKAKMTLEGTINNLKADISNVEEVAKLYGLDNLTYDE
KERLKTAKKKIDVGPIFTTLLSKRANIGFTTGGHTGEDVFLYSYGPQKPYGLIQNTDVAKTMAKAMGFNLEKVTNKLFVE
SESAFKQNGATVTIDKTDVANPVLIVKRNNVTAQLFVNKNIIRIKNKEYELGSIVVESNGKVYVPEEAIHLFRKHSR

Sequences:

>Translated_557_residues
MSELALKMKRLLLVGTIILSMLCTENLMNYHTVEAKVKKVERKPKNVIIMVMDGTSSTATTLARLYKGKALALDEIVTGG
VRTYSAESAITDSAPAVTALATGNKSNSGYVGVLPSIVSSPGLKPMKEEDKLRPVANVLEGAKRTGRATGIVATAEIQHA
TPAGFSAHHVNRNNFEVLAEQQVYQNIDVVLGGGKAALLPETDSGIRKDGEDLVKVIKNKGYDFVETKEALLGSKSNKIW
GSFSLNALAFDMDREATNPEQPTLSQMTEKAIQTLSKDKDGFFLFVEGSKPDWAAHVNDPIGMISDVLAFDNAVAEALKF
AKKDGNTMLIAVADHGNSGISIGNMNTTKGYNTTPVSAYIYPLKKAKMTLEGTINNLKADISNVEEVAKLYGLDNLTYDE
KERLKTAKKKIDVGPIFTTLLSKRANIGFTTGGHTGEDVFLYSYGPQKPYGLIQNTDVAKTMAKAMGFNLEKVTNKLFVE
SESAFKQNGATVTIDKTDVANPVLIVKRNNVTAQLFVNKNIIRIKNKEYELGSIVVESNGKVYVPEEAIHLFRKHSR
>Mature_556_residues
SELALKMKRLLLVGTIILSMLCTENLMNYHTVEAKVKKVERKPKNVIIMVMDGTSSTATTLARLYKGKALALDEIVTGGV
RTYSAESAITDSAPAVTALATGNKSNSGYVGVLPSIVSSPGLKPMKEEDKLRPVANVLEGAKRTGRATGIVATAEIQHAT
PAGFSAHHVNRNNFEVLAEQQVYQNIDVVLGGGKAALLPETDSGIRKDGEDLVKVIKNKGYDFVETKEALLGSKSNKIWG
SFSLNALAFDMDREATNPEQPTLSQMTEKAIQTLSKDKDGFFLFVEGSKPDWAAHVNDPIGMISDVLAFDNAVAEALKFA
KKDGNTMLIAVADHGNSGISIGNMNTTKGYNTTPVSAYIYPLKKAKMTLEGTINNLKADISNVEEVAKLYGLDNLTYDEK
ERLKTAKKKIDVGPIFTTLLSKRANIGFTTGGHTGEDVFLYSYGPQKPYGLIQNTDVAKTMAKAMGFNLEKVTNKLFVES
ESAFKQNGATVTIDKTDVANPVLIVKRNNVTAQLFVNKNIIRIKNKEYELGSIVVESNGKVYVPEEAIHLFRKHSR

Specific function: Unknown

COG id: COG1785

COG function: function code P; Alkaline phosphatase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkaline phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI157266296, Length=491, Percent_Identity=26.6802443991853, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI157266292, Length=483, Percent_Identity=25.2587991718427, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI94721246, Length=476, Percent_Identity=26.890756302521, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI116734717, Length=338, Percent_Identity=29.2899408284024, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI294660770, Length=334, Percent_Identity=28.4431137724551, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI294660772, Length=290, Percent_Identity=29.6551724137931, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI48994877, Length=351, Percent_Identity=31.9088319088319, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6320689, Length=526, Percent_Identity=29.8479087452471, Blast_Score=181, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24657827, Length=471, Percent_Identity=28.4501061571125, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI85725200, Length=343, Percent_Identity=30.0291545189504, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI85815833, Length=343, Percent_Identity=30.0291545189504, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI21355981, Length=327, Percent_Identity=31.1926605504587, Blast_Score=132, Evalue=8e-31,
Organism=Drosophila melanogaster, GI19921912, Length=479, Percent_Identity=27.7661795407098, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24657835, Length=473, Percent_Identity=27.906976744186, Blast_Score=129, Evalue=7e-30,
Organism=Drosophila melanogaster, GI21355149, Length=339, Percent_Identity=29.4985250737463, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24657842, Length=471, Percent_Identity=27.3885350318471, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21355151, Length=330, Percent_Identity=29.6969696969697, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI18859923, Length=430, Percent_Identity=26.7441860465116, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24585213, Length=342, Percent_Identity=30.1169590643275, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24651554, Length=476, Percent_Identity=25.6302521008403, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21358067, Length=340, Percent_Identity=27.9411764705882, Blast_Score=109, Evalue=4e-24,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR001952
- InterPro:   IPR018299
- InterPro:   IPR017850 [H]

Pfam domain/function: PF00245 Alk_phosphatase [H]

EC number: =3.1.3.1 [H]

Molecular weight: Translated: 60561; Mature: 60430

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELALKMKRLLLVGTIILSMLCTENLMNYHTVEAKVKKVERKPKNVIIMVMDGTSSTAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHH
TLARLYKGKALALDEIVTGGVRTYSAESAITDSAPAVTALATGNKSNSGYVGVLPSIVSS
HHHHHHCCCCEEHHHHHCCCCEEECCCCCCCCCCCCEEEEEECCCCCCCEEEECHHHHCC
PGLKPMKEEDKLRPVANVLEGAKRTGRATGIVATAEIQHATPAGFSAHHVNRNNFEVLAE
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEECCCCCCHHEEEH
QQVYQNIDVVLGGGKAALLPETDSGIRKDGEDLVKVIKNKGYDFVETKEALLGSKSNKIW
HHHHCCCEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEE
GSFSLNALAFDMDREATNPEQPTLSQMTEKAIQTLSKDKDGFFLFVEGSKPDWAAHVNDP
EEEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCCH
IGMISDVLAFDNAVAEALKFAKKDGNTMLIAVADHGNSGISIGNMNTTKGYNTTPVSAYI
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECCCCCCCCCCCCCCEEEE
YPLKKAKMTLEGTINNLKADISNVEEVAKLYGLDNLTYDEKERLKTAKKKIDVGPIFTTL
EEHHHHEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
LSKRANIGFTTGGHTGEDVFLYSYGPQKPYGLIQNTDVAKTMAKAMGFNLEKVTNKLFVE
HHCCCCCCEECCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHEEC
SESAFKQNGATVTIDKTDVANPVLIVKRNNVTAQLFVNKNIIRIKNKEYELGSIVVESNG
CCHHHHCCCCEEEEECCCCCCCEEEEEECCEEEEEEECCCEEEEECCCEEEEEEEEECCC
KVYVPEEAIHLFRKHSR
CEECCHHHHHHHHHCCC
>Mature Secondary Structure 
SELALKMKRLLLVGTIILSMLCTENLMNYHTVEAKVKKVERKPKNVIIMVMDGTSSTAT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHH
TLARLYKGKALALDEIVTGGVRTYSAESAITDSAPAVTALATGNKSNSGYVGVLPSIVSS
HHHHHHCCCCEEHHHHHCCCCEEECCCCCCCCCCCCEEEEEECCCCCCCEEEECHHHHCC
PGLKPMKEEDKLRPVANVLEGAKRTGRATGIVATAEIQHATPAGFSAHHVNRNNFEVLAE
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCEECCCCCCHHEEEH
QQVYQNIDVVLGGGKAALLPETDSGIRKDGEDLVKVIKNKGYDFVETKEALLGSKSNKIW
HHHHCCCEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEE
GSFSLNALAFDMDREATNPEQPTLSQMTEKAIQTLSKDKDGFFLFVEGSKPDWAAHVNDP
EEEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCCH
IGMISDVLAFDNAVAEALKFAKKDGNTMLIAVADHGNSGISIGNMNTTKGYNTTPVSAYI
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEECCCCCCCCCCCCCCEEEE
YPLKKAKMTLEGTINNLKADISNVEEVAKLYGLDNLTYDEKERLKTAKKKIDVGPIFTTL
EEHHHHEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
LSKRANIGFTTGGHTGEDVFLYSYGPQKPYGLIQNTDVAKTMAKAMGFNLEKVTNKLFVE
HHCCCCCCEECCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHEEC
SESAFKQNGATVTIDKTDVANPVLIVKRNNVTAQLFVNKNIIRIKNKEYELGSIVVESNG
CCHHHHCCCCEEEEECCCCCCCEEEEEECCEEEEEEECCCEEEEECCCEEEEEEEEECCC
KVYVPEEAIHLFRKHSR
CEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8113174; 9579061; 9384377; 1898729; 2125017; 2105301; 8144469 [H]