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The map label for this gene is lrpC [H]

Identifier: 118478217

GI number: 118478217

Start: 2736285

End: 2736719

Strand: Direct

Name: lrpC [H]

Synonym: BALH_2576

Alternate gene names: 118478217

Gene position: 2736285-2736719 (Clockwise)

Preceding gene: 118478210

Following gene: 118478222

Centisome position: 52.05

GC content: 33.1

Gene sequence:

>435_bases
ATGGATGAAATCGATAAGAAAATAACCCTTTTATTACAAGAGGATGCCAGAATGACAATTACAGAAATGACTGAGCATCT
ACACCTCAGCCGTCCTAGTGTCACAGAAAGATTAAAAAGGTTACAAGATGCAGGAATAATTGAAAAGTATACAGCTCGAA
TATCACTTGATATAATTGGAAAATCAATTCAAGCATTTTTAAGGATCGAAAACTTAAAGGTTCCATGCAAAAAATTTGAG
GAGAAAATATACGAAGAACAGAGGATTCTTGAATGCCACCGAGTAACAGGTGAAAGCAGCTATTACTTAAAAGTAGCAGT
TCACTCTATGAAGGAATTAGAAGAATTAATTGATATCGTTATACCATTTGGAACAGTTAAAACTTCTATGATCTTATCTT
CACCAATACCATATCGATCGGTAATTATAGAATAA

Upstream 100 bases:

>100_bases
CTCTATTCAATATACAAAAGTGTATGTAATTTAATATTAGATTTTATATTATGTATTTATTTCAGAAATTTATTTTCAAT
TTTGTAAAGGAGCGTATTTC

Downstream 100 bases:

>100_bases
CAATAAAAAAAGGATCGATCAAAAGATCAATCCTTTACTCTACTTCATTTAAGAAAAATAGCGTTATAACGCCAGGTCCT
GTATGTGCTCCGATTGCTGC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MDEIDKKITLLLQEDARMTITEMTEHLHLSRPSVTERLKRLQDAGIIEKYTARISLDIIGKSIQAFLRIENLKVPCKKFE
EKIYEEQRILECHRVTGESSYYLKVAVHSMKELEELIDIVIPFGTVKTSMILSSPIPYRSVIIE

Sequences:

>Translated_144_residues
MDEIDKKITLLLQEDARMTITEMTEHLHLSRPSVTERLKRLQDAGIIEKYTARISLDIIGKSIQAFLRIENLKVPCKKFE
EKIYEEQRILECHRVTGESSYYLKVAVHSMKELEELIDIVIPFGTVKTSMILSSPIPYRSVIIE
>Mature_144_residues
MDEIDKKITLLLQEDARMTITEMTEHLHLSRPSVTERLKRLQDAGIIEKYTARISLDIIGKSIQAFLRIENLKVPCKKFE
EKIYEEQRILECHRVTGESSYYLKVAVHSMKELEELIDIVIPFGTVKTSMILSSPIPYRSVIIE

Specific function: Mediates A Global Response To Leucine. Exogenous Leucine Affects The Expression Of A Number Of Different Operons; Lrp Mediates This Effect For At Least Some Of These Operons. For Example It Is Regulator Of The Branched-Chain Amino Acid Transport Genes. [

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=120, Percent_Identity=31.6666666666667, Blast_Score=63, Evalue=9e-12,
Organism=Escherichia coli, GI87081742, Length=120, Percent_Identity=30.8333333333333, Blast_Score=60, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR000835
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 16720; Mature: 16720

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEIDKKITLLLQEDARMTITEMTEHLHLSRPSVTERLKRLQDAGIIEKYTARISLDIIG
CCCHHHHHHHEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
KSIQAFLRIENLKVPCKKFEEKIYEEQRILECHRVTGESSYYLKVAVHSMKELEELIDIV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHH
IPFGTVKTSMILSSPIPYRSVIIE
HCCCHHHHHHHHCCCCCHHHEECC
>Mature Secondary Structure
MDEIDKKITLLLQEDARMTITEMTEHLHLSRPSVTERLKRLQDAGIIEKYTARISLDIIG
CCCHHHHHHHEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
KSIQAFLRIENLKVPCKKFEEKIYEEQRILECHRVTGESSYYLKVAVHSMKELEELIDIV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHH
IPFGTVKTSMILSSPIPYRSVIIE
HCCCHHHHHHHHCCCCCHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]