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The map label for this gene is dapA [H]

Identifier: 118478184

GI number: 118478184

Start: 2702908

End: 2703825

Strand: Reverse

Name: dapA [H]

Synonym: BALH_2541

Alternate gene names: 118478184

Gene position: 2703825-2702908 (Counterclockwise)

Preceding gene: 118478185

Following gene: 118478183

Centisome position: 51.43

GC content: 36.6

Gene sequence:

>918_bases
ATGGTAAGGGGAGAGATAAATATGAAAACAATTAAAGGGGCATTTCCAGTATTAATCACACCGATGGATGAGTTTCAAGA
AATTAATTGGAACGGTGTAAAACAAAACGTAAACTACTTTATTGAGCAAAAAGTGGCTGGCATTATTATAAACGGAAGCA
CAGGAGAGTTTGTTAGTTTGTCAAAAGAAGAACGATTTAAAATGGTAGAAACAGTATTAAAAGAAGTTGATGGCCGTATT
CCGGTTATTGTTGGAACTGCAGCAGAAACGACGAAAGAAACGATTGAATTTACAAAACATGCAGAAACGCACGGAGTGGA
CTGCGCATTAATTATTAACTCATACTATTGTAAGCCAAAAGAAGAGGAAATTTATTTTCACTTTAAAGAAATCTCAAATG
CTGTAAATATACCAATTATGTTATATAATAACCCGTTTACATCTGGTGTTGATATGAGTACAGAACTCATGCTACGTATC
GGGAAAGACTGTGAAAATGTTACACATATTAAAGAATCTAGCGGAGATATTCGAAAAGCAAGAGATTTAGTAAGACAAGG
CGAAGGTGCTTTTCAAGTCTTCTGCGGATCTGAAGATTTAGTTATGGAATCTTATTTAGTTGGTGCGACGGGATGGGTTT
CAGTAGCAGGAAATGTTGTACCGGGACTTGTTACGAAAATGTATGAGCATTTTCAAAATGGTGAATTAGAAAAAGCTTGG
GAAATAAACGATGCAATTTTACCTCTTTGTGAGTTCCTGGAGGGATCAGGGAAATATGTGCAAATCGTGAAACGTTCTAT
GGAATTACACGGGCAAGCTGGGGGACCTTCTCGTTATCCAAGACTTGGGTTAACTGAAGAAGAAGATCAAAAACTTCAAG
CGATTATTTCAAAAATTGCAGCTCATGCAGCTGTTTAA

Upstream 100 bases:

>100_bases
TACATTTTCCGTTTTGAAAGTAGAGGTTTTATTACAGGGGTGCAGACATTTCTACTAGACCCTACAGATCCATTTCCAGC
AGGATTTTTATTAAAATAAA

Downstream 100 bases:

>100_bases
TTAAGGAGGAGAGCATATATGTTAACGACAAATATTGAGTTGAAACCAAAAGTGAAAGCGTTTTTAGATGAAGAGATTAA
AATGTTTATTAATGGTGAAT

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MVRGEINMKTIKGAFPVLITPMDEFQEINWNGVKQNVNYFIEQKVAGIIINGSTGEFVSLSKEERFKMVETVLKEVDGRI
PVIVGTAAETTKETIEFTKHAETHGVDCALIINSYYCKPKEEEIYFHFKEISNAVNIPIMLYNNPFTSGVDMSTELMLRI
GKDCENVTHIKESSGDIRKARDLVRQGEGAFQVFCGSEDLVMESYLVGATGWVSVAGNVVPGLVTKMYEHFQNGELEKAW
EINDAILPLCEFLEGSGKYVQIVKRSMELHGQAGGPSRYPRLGLTEEEDQKLQAIISKIAAHAAV

Sequences:

>Translated_305_residues
MVRGEINMKTIKGAFPVLITPMDEFQEINWNGVKQNVNYFIEQKVAGIIINGSTGEFVSLSKEERFKMVETVLKEVDGRI
PVIVGTAAETTKETIEFTKHAETHGVDCALIINSYYCKPKEEEIYFHFKEISNAVNIPIMLYNNPFTSGVDMSTELMLRI
GKDCENVTHIKESSGDIRKARDLVRQGEGAFQVFCGSEDLVMESYLVGATGWVSVAGNVVPGLVTKMYEHFQNGELEKAW
EINDAILPLCEFLEGSGKYVQIVKRSMELHGQAGGPSRYPRLGLTEEEDQKLQAIISKIAAHAAV
>Mature_305_residues
MVRGEINMKTIKGAFPVLITPMDEFQEINWNGVKQNVNYFIEQKVAGIIINGSTGEFVSLSKEERFKMVETVLKEVDGRI
PVIVGTAAETTKETIEFTKHAETHGVDCALIINSYYCKPKEEEIYFHFKEISNAVNIPIMLYNNPFTSGVDMSTELMLRI
GKDCENVTHIKESSGDIRKARDLVRQGEGAFQVFCGSEDLVMESYLVGATGWVSVAGNVVPGLVTKMYEHFQNGELEKAW
EINDAILPLCEFLEGSGKYVQIVKRSMELHGQAGGPSRYPRLGLTEEEDQKLQAIISKIAAHAAV

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=294, Percent_Identity=25.5102040816327, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI13540533, Length=279, Percent_Identity=30.8243727598566, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI87082415, Length=267, Percent_Identity=27.7153558052434, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786463, Length=263, Percent_Identity=28.1368821292776, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788823, Length=237, Percent_Identity=30.379746835443, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789620, Length=234, Percent_Identity=23.5042735042735, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33989; Mature: 33989

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00665 DHDPS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRGEINMKTIKGAFPVLITPMDEFQEINWNGVKQNVNYFIEQKVAGIIINGSTGEFVSL
CCCCCCCCEEECCCCCEEECCHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCEEEC
SKEERFKMVETVLKEVDGRIPVIVGTAAETTKETIEFTKHAETHGVDCALIINSYYCKPK
CHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCC
EEEIYFHFKEISNAVNIPIMLYNNPFTSGVDMSTELMLRIGKDCENVTHIKESSGDIRKA
CCHHEEEHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCHHHHH
RDLVRQGEGAFQVFCGSEDLVMESYLVGATGWVSVAGNVVPGLVTKMYEHFQNGELEKAW
HHHHHCCCCCEEEEECCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCHHH
EINDAILPLCEFLEGSGKYVQIVKRSMELHGQAGGPSRYPRLGLTEEEDQKLQAIISKIA
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AHAAV
HHHCC
>Mature Secondary Structure
MVRGEINMKTIKGAFPVLITPMDEFQEINWNGVKQNVNYFIEQKVAGIIINGSTGEFVSL
CCCCCCCCEEECCCCCEEECCHHHHHHCCCCCHHHHHHHHHCCCEEEEEEECCCCCEEEC
SKEERFKMVETVLKEVDGRIPVIVGTAAETTKETIEFTKHAETHGVDCALIINSYYCKPK
CHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCC
EEEIYFHFKEISNAVNIPIMLYNNPFTSGVDMSTELMLRIGKDCENVTHIKESSGDIRKA
CCHHEEEHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCHHHHH
RDLVRQGEGAFQVFCGSEDLVMESYLVGATGWVSVAGNVVPGLVTKMYEHFQNGELEKAW
HHHHHCCCCCEEEEECCCHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCHHH
EINDAILPLCEFLEGSGKYVQIVKRSMELHGQAGGPSRYPRLGLTEEEDQKLQAIISKIA
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
AHAAV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]