Click here to switch to the map view.

The map label for this gene is acoR [H]

Identifier: 118478125

GI number: 118478125

Start: 2645896

End: 2647746

Strand: Reverse

Name: acoR [H]

Synonym: BALH_2482

Alternate gene names: 118478125

Gene position: 2647746-2645896 (Counterclockwise)

Preceding gene: 118478126

Following gene: 118478124

Centisome position: 50.37

GC content: 35.6

Gene sequence:

>1851_bases
ATGTTAGCTTCACCATTTTACTTACATACATGGAAAAAGTTTGTTGATGAAGGAGTCCTTGATTCGAACCGTATAAACGA
AAGAATTTCAGAGTCATGGTATCGATGTAAACAAGCAAATGTGAATCCTCATATGAATAAAGGTCAGAAAATTTTGTCTT
CTAATATTTTTCAAGACCAAAAGAAAAAGAGTGAAATCTTCTTAGATATAGCAATCCCTCAAATACAAAATATGAGAAAA
ACCATTGATGAACTGCAAATGATGGCATTATTAATTGATCCAGATGGTTACGTTCTATCGTTAAGTGGAAATGAACAAAC
ATTGAAACGAGCAAAACATATTAACTTCATTGAAGGTGTGAAATGGACGGAAGCAGCTGTTGGTACAAATGCGATAGGAA
CAGCGCTTGAGATTGAAGAGGCTATTATGATAAGTGGTACAGAGCATTATTCTGTCGCATCTCATAGCTGGAGCTGTGCG
GCTGCTCCCATTCATAATGATGACGGGAAATTAATTGGAGTTCTAGATTTCTCTTGTCCCATTGAATTTTCCCATCCGTA
TATGCTCGGGATGGTAACTTCGATTGCACATGCGATTGAACGTGAATGTAGTATTCGAGTGCATCAAAATGAATTACATT
TAATCCATCGTTTTTTAGATGTAATTGACAGTGATGAACAAGTTGTTATTTGTAATCATCGTGATGTTATCGTTTCTGCA
AGCAAGAAGGTTCGAGAACGAGTTTCTAATTGGTCACGAATGAAACTTGAAGATCTAATGCAAAATGGATTGAAACCTAA
ATTAGAAGTACCAGTATATAGTAATGATAGAATGATCGGGAAATGTATTTATGTAAAGGAAAATAAACAAGGAAATGTAT
TTTCTACTTCCCCATTTATAAACGGAATTACGTTCCCTGGAGTTATTGGGACAAGCAATGCATTTCAACATACTTTAGAA
GAAATTAAGCTAGTATCTCCAACTGACGCTAGTGTATATGTTTGTGGTGAAACAGGTGTAGGGAAAGAATATGTAGCGAG
AGCGATTCACGAAAATAGTCCAAGAAAAAATGGTCCTTTTATAGCTGTTAACTGCGGTTCATTGCCGAAAGAATTAATGG
AAAGTGAATTATTCGGTTATGCTGAAGGTGCATTTACAGGTGCGCGGCGCCACGGATATAAAGGGAAATTCGAACAAGCA
GACGGAGGGACAATATTTTTAGATGAAATTGGTGAAGTGCCGCCAGAGATGCAAGTCGCATTATTGCGTGTTTTACAAGA
ACGAACAGTAACCCCAATTGGCAGTTCAAAAGAGATACCAGTAAATATTCGTATTATTACTGCGACACATAAAGATTTAT
TGCGATTAGTTGAGGAAGGCAAGTTCCGTCAAGATTTATATTATCGTTTACATGTTTATCCACTATATGTTCCATCGTTA
ATAGAAAGAAAAGAGGATATTCCGTACTTCATACAACATTTTTGTGAACGAAAGAATTGGAATGTTGCATTTCCGAAGAG
TATTTGTAATCAGTTTTCACAGCATACATGGCCCGGAAATATTCGAGAATTATTAAATGCATTAGAACGTATTTACATTT
TGTCGCAAGGACGGGAAATATGCGAAAAACAAATCTCTTTTTTATTACAAACAATGATGAGAAATCAACATCAGCTTGAA
TTGCAAACAGAAAATAAAACAGAGGACACATTGAATTTCCGTGAAAAAATACAGCGTGATAGCATGATTGAAGCGCTAGA
AAAGACGAACGGAAATGTTTCGTTAGCTGCAAAACTGTTAGATGTACCTCGAAGTACATTTTATAAACGAATGCAAAAAT
ATAAGTTATAA

Upstream 100 bases:

>100_bases
GTGTCGTCTTTCTAGTTTTATTGAAAACGCTTTTATTCAGTTTTATAATAAAGGTATGTTTTTTACAGATCTCCAAAACA
ATAAATAGGGAGATGATACA

Downstream 100 bases:

>100_bases
AGTAGATTTTTGTAATCTACTTTTTCTTTGTGAGCTCATGTTCTGTCGGAATGTGCGCTTACCGGGGAAATAATAGAATA
GTTAGAAATTAATTCCCGGA

Product: sigma-54-dependent transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQKKKSEIFLDIAIPQIQNMRK
TIDELQMMALLIDPDGYVLSLSGNEQTLKRAKHINFIEGVKWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCA
AAPIHNDDGKLIGVLDFSCPIEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSDEQVVICNHRDVIVSA
SKKVRERVSNWSRMKLEDLMQNGLKPKLEVPVYSNDRMIGKCIYVKENKQGNVFSTSPFINGITFPGVIGTSNAFQHTLE
EIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPFIAVNCGSLPKELMESELFGYAEGAFTGARRHGYKGKFEQA
DGGTIFLDEIGEVPPEMQVALLRVLQERTVTPIGSSKEIPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
IERKEDIPYFIQHFCERKNWNVAFPKSICNQFSQHTWPGNIRELLNALERIYILSQGREICEKQISFLLQTMMRNQHQLE
LQTENKTEDTLNFREKIQRDSMIEALEKTNGNVSLAAKLLDVPRSTFYKRMQKYKL

Sequences:

>Translated_616_residues
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQKKKSEIFLDIAIPQIQNMRK
TIDELQMMALLIDPDGYVLSLSGNEQTLKRAKHINFIEGVKWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCA
AAPIHNDDGKLIGVLDFSCPIEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSDEQVVICNHRDVIVSA
SKKVRERVSNWSRMKLEDLMQNGLKPKLEVPVYSNDRMIGKCIYVKENKQGNVFSTSPFINGITFPGVIGTSNAFQHTLE
EIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPFIAVNCGSLPKELMESELFGYAEGAFTGARRHGYKGKFEQA
DGGTIFLDEIGEVPPEMQVALLRVLQERTVTPIGSSKEIPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
IERKEDIPYFIQHFCERKNWNVAFPKSICNQFSQHTWPGNIRELLNALERIYILSQGREICEKQISFLLQTMMRNQHQLE
LQTENKTEDTLNFREKIQRDSMIEALEKTNGNVSLAAKLLDVPRSTFYKRMQKYKL
>Mature_616_residues
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQKKKSEIFLDIAIPQIQNMRK
TIDELQMMALLIDPDGYVLSLSGNEQTLKRAKHINFIEGVKWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCA
AAPIHNDDGKLIGVLDFSCPIEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSDEQVVICNHRDVIVSA
SKKVRERVSNWSRMKLEDLMQNGLKPKLEVPVYSNDRMIGKCIYVKENKQGNVFSTSPFINGITFPGVIGTSNAFQHTLE
EIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPFIAVNCGSLPKELMESELFGYAEGAFTGARRHGYKGKFEQA
DGGTIFLDEIGEVPPEMQVALLRVLQERTVTPIGSSKEIPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
IERKEDIPYFIQHFCERKNWNVAFPKSICNQFSQHTWPGNIRELLNALERIYILSQGREICEKQISFLLQTMMRNQHQLE
LQTENKTEDTLNFREKIQRDSMIEALEKTNGNVSLAAKLLDVPRSTFYKRMQKYKL

Specific function: Acts as a transcriptional activator of the acoABCL operon encoding the acetoin dehydrogenase complex [H]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=327, Percent_Identity=42.8134556574924, Blast_Score=268, Evalue=1e-72,
Organism=Escherichia coli, GI87082117, Length=326, Percent_Identity=40.7975460122699, Blast_Score=260, Evalue=2e-70,
Organism=Escherichia coli, GI1788905, Length=315, Percent_Identity=42.2222222222222, Blast_Score=255, Evalue=5e-69,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=37.3831775700935, Blast_Score=228, Evalue=7e-61,
Organism=Escherichia coli, GI1788550, Length=317, Percent_Identity=39.4321766561514, Blast_Score=222, Evalue=6e-59,
Organism=Escherichia coli, GI1789087, Length=317, Percent_Identity=38.1703470031546, Blast_Score=216, Evalue=2e-57,
Organism=Escherichia coli, GI1790299, Length=347, Percent_Identity=35.7348703170029, Blast_Score=214, Evalue=2e-56,
Organism=Escherichia coli, GI1786524, Length=322, Percent_Identity=37.888198757764, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI87082152, Length=321, Percent_Identity=35.8255451713396, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI87081858, Length=647, Percent_Identity=24.7295208655332, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1787583, Length=301, Percent_Identity=34.8837209302326, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI87081872, Length=229, Percent_Identity=41.0480349344978, Blast_Score=179, Evalue=6e-46,
Organism=Escherichia coli, GI1789828, Length=321, Percent_Identity=31.1526479750779, Blast_Score=150, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 70341; Mature: 70341

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQ
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KKKSEIFLDIAIPQIQNMRKTIDELQMMALLIDPDGYVLSLSGNEQTLKRAKHINFIEGV
HCCCEEEEEEECHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCHHHHHHHHHCCHHHCC
KWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCAAAPIHNDDGKLIGVLDFSCP
CHHHHHCCCCCCCCHHEECCEEEEECCCCEEECCCCCCEEECCEECCCCCEEEEEECCCC
IEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSDEQVVICNHRDVIVSA
CCCCCCHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCEEEEC
SKKVRERVSNWSRMKLEDLMQNGLKPKLEVPVYSNDRMIGKCIYVKENKQGNVFSTSPFI
HHHHHHHHCCCHHHHHHHHHHCCCCCEEEECEECCCCEEEEEEEEEECCCCCEEECCCCC
NGITFPGVIGTSNAFQHTLEEIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPF
CCCCCCCCCCCCHHHHHHHHHCEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCE
IAVNCGSLPKELMESELFGYAEGAFTGARRHGYKGKFEQADGGTIFLDEIGEVPPEMQVA
EEEECCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEHHHCCCCHHHHHH
LLRVLQERTVTPIGSSKEIPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
HHHHHHHCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHCCCHHHCEEEEEEEEEEHHHHH
IERKEDIPYFIQHFCERKNWNVAFPKSICNQFSQHTWPGNIRELLNALERIYILSQGREI
HHHCCCCHHHHHHHHCCCCCCEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
CEKQISFLLQTMMRNQHQLELQTENKTEDTLNFREKIQRDSMIEALEKTNGNVSLAAKLL
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHH
DVPRSTFYKRMQKYKL
HCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLASPFYLHTWKKFVDEGVLDSNRINERISESWYRCKQANVNPHMNKGQKILSSNIFQDQ
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KKKSEIFLDIAIPQIQNMRKTIDELQMMALLIDPDGYVLSLSGNEQTLKRAKHINFIEGV
HCCCEEEEEEECHHHHHHHHHHHHHHHHHEEECCCCEEEEECCCHHHHHHHHHCCHHHCC
KWTEAAVGTNAIGTALEIEEAIMISGTEHYSVASHSWSCAAAPIHNDDGKLIGVLDFSCP
CHHHHHCCCCCCCCHHEECCEEEEECCCCEEECCCCCCEEECCEECCCCCEEEEEECCCC
IEFSHPYMLGMVTSIAHAIERECSIRVHQNELHLIHRFLDVIDSDEQVVICNHRDVIVSA
CCCCCCHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHCCCCEEEEECCCCEEEEC
SKKVRERVSNWSRMKLEDLMQNGLKPKLEVPVYSNDRMIGKCIYVKENKQGNVFSTSPFI
HHHHHHHHCCCHHHHHHHHHHCCCCCEEEECEECCCCEEEEEEEEEECCCCCEEECCCCC
NGITFPGVIGTSNAFQHTLEEIKLVSPTDASVYVCGETGVGKEYVARAIHENSPRKNGPF
CCCCCCCCCCCCHHHHHHHHHCEECCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCCCCE
IAVNCGSLPKELMESELFGYAEGAFTGARRHGYKGKFEQADGGTIFLDEIGEVPPEMQVA
EEEECCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCEEEEHHHCCCCHHHHHH
LLRVLQERTVTPIGSSKEIPVNIRIITATHKDLLRLVEEGKFRQDLYYRLHVYPLYVPSL
HHHHHHHCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHCCCHHHCEEEEEEEEEEHHHHH
IERKEDIPYFIQHFCERKNWNVAFPKSICNQFSQHTWPGNIRELLNALERIYILSQGREI
HHHCCCCHHHHHHHHCCCCCCEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHH
CEKQISFLLQTMMRNQHQLELQTENKTEDTLNFREKIQRDSMIEALEKTNGNVSLAAKLL
HHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHH
DVPRSTFYKRMQKYKL
HCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377; 10368162 [H]