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The map label for this gene is fbaA [H]

Identifier: 118477917

GI number: 118477917

Start: 2426106

End: 2426996

Strand: Direct

Name: fbaA [H]

Synonym: BALH_2262

Alternate gene names: 118477917

Gene position: 2426106-2426996 (Clockwise)

Preceding gene: 118477916

Following gene: 118477918

Centisome position: 46.15

GC content: 38.16

Gene sequence:

>891_bases
TTGGTTTTACATGTAATAAATAATATTGAAATAGGAGAGTATGTAATGCCATTAGTTCAAATGAAAGATATTTTAATGAA
AGCATATCAAGAGAATTATGGGGTTGGAGCTTTTAGTGTCGCGAATATGAAAATGGTAATGGGAGCTATTAAAGCAGCTG
AAGAGTTAAGTTCGCCGCTTATTCTACAAATTGCGGAAGTTCGTTTGAATCATTCGCCAATTCATATGATTGGTCCATTG
ATGGTAGCTGCAGCGAAACAAGCAACTGTTCCAGTAGCAGTTCACTTTGATCACGGTATGACATTTAATAAGATTCAAGA
GACGTTAGAAATTGGTTTTAGTTCGGTTATGTTTGATGGCTCTCACTATCCGTTAGAAGAGAATATCCAAAAGACAAAAG
AAATTGTAGAACTTGCGAAACAGTATGGAGCGACGGTAGAAGCTGAGATTGGTAGAGTTGGTGGTAGTGAGGACGGATCA
GAAGATATTGAAATGTTGCTGACAAGCACTACAGAAGCAAAACGATTTGCTGAAGAAACAGACGTTGATGCGTTAGCGGT
TGCAATTGGAAATGCGCATGGTATGTACAATGGCGATCCTAATTTACGATTAGACCGCCTACAAGAGATTAATGAAGTAG
TCCATATCCCGCTCGTTTTACATGGCGGCTCTGGCATTAGTCCAGAGGATTTCAAGCGATGTATTCAACATGGTGTTCGA
AAAATAAATGTAGCAACAGCCACATTTCAGAATGTAATTACTGCTGTTAACACTGCCGTCCTAAATAATCCGTATTCAGA
TTACTTTACGTACCACCAGGATGTTATTGAGGCTGCATACGAAAATGTTAAAATTCATATGCAAATATTCGGAAGTGAAA
ACAGAGTATAA

Upstream 100 bases:

>100_bases
AAAAAGCCGGTCTGTAATTTAAGCATTTTAAGATTATCCATAAGTAAATGGTATGGTAATCAACATGTCTCCTTACAAAA
GGGGTAAAAAGACGTGAAGG

Downstream 100 bases:

>100_bases
ATAGAAAAGCTTTCTTCAGTAATAGTTAGACGAAACTCGGAATGTAGTGAACTGAAAAAAGTAGAGAATGATTGAGTAGC
CATTAAATAAAAGGGGGAGA

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MVLHVINNIEIGEYVMPLVQMKDILMKAYQENYGVGAFSVANMKMVMGAIKAAEELSSPLILQIAEVRLNHSPIHMIGPL
MVAAAKQATVPVAVHFDHGMTFNKIQETLEIGFSSVMFDGSHYPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGS
EDIEMLLTSTTEAKRFAEETDVDALAVAIGNAHGMYNGDPNLRLDRLQEINEVVHIPLVLHGGSGISPEDFKRCIQHGVR
KINVATATFQNVITAVNTAVLNNPYSDYFTYHQDVIEAAYENVKIHMQIFGSENRV

Sequences:

>Translated_296_residues
MVLHVINNIEIGEYVMPLVQMKDILMKAYQENYGVGAFSVANMKMVMGAIKAAEELSSPLILQIAEVRLNHSPIHMIGPL
MVAAAKQATVPVAVHFDHGMTFNKIQETLEIGFSSVMFDGSHYPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGS
EDIEMLLTSTTEAKRFAEETDVDALAVAIGNAHGMYNGDPNLRLDRLQEINEVVHIPLVLHGGSGISPEDFKRCIQHGVR
KINVATATFQNVITAVNTAVLNNPYSDYFTYHQDVIEAAYENVKIHMQIFGSENRV
>Mature_296_residues
MVLHVINNIEIGEYVMPLVQMKDILMKAYQENYGVGAFSVANMKMVMGAIKAAEELSSPLILQIAEVRLNHSPIHMIGPL
MVAAAKQATVPVAVHFDHGMTFNKIQETLEIGFSSVMFDGSHYPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGS
EDIEMLLTSTTEAKRFAEETDVDALAVAIGNAHGMYNGDPNLRLDRLQEINEVVHIPLVLHGGSGISPEDFKRCIQHGVR
KINVATATFQNVITAVNTAVLNNPYSDYFTYHQDVIEAAYENVKIHMQIFGSENRV

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=284, Percent_Identity=38.0281690140845, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI87082041, Length=283, Percent_Identity=36.0424028268551, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1788072, Length=269, Percent_Identity=36.4312267657993, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1789293, Length=304, Percent_Identity=24.3421052631579, Blast_Score=72, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322790, Length=296, Percent_Identity=27.027027027027, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011289
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 32643; Mature: 32643

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLHVINNIEIGEYVMPLVQMKDILMKAYQENYGVGAFSVANMKMVMGAIKAAEELSSPL
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCH
ILQIAEVRLNHSPIHMIGPLMVAAAKQATVPVAVHFDHGMTFNKIQETLEIGFSSVMFDG
HEEHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCHHHEEECC
SHYPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGSEDIEMLLTSTTEAKRFAEET
CCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHC
DVDALAVAIGNAHGMYNGDPNLRLDRLQEINEVVHIPLVLHGGSGISPEDFKRCIQHGVR
CCHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHH
KINVATATFQNVITAVNTAVLNNPYSDYFTYHQDVIEAAYENVKIHMQIFGSENRV
EEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCC
>Mature Secondary Structure
MVLHVINNIEIGEYVMPLVQMKDILMKAYQENYGVGAFSVANMKMVMGAIKAAEELSSPL
CEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHCCCH
ILQIAEVRLNHSPIHMIGPLMVAAAKQATVPVAVHFDHGMTFNKIQETLEIGFSSVMFDG
HEEHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCHHHEEECC
SHYPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGSEDIEMLLTSTTEAKRFAEET
CCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHC
DVDALAVAIGNAHGMYNGDPNLRLDRLQEINEVVHIPLVLHGGSGISPEDFKRCIQHGVR
CCHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHH
KINVATATFQNVITAVNTAVLNNPYSDYFTYHQDVIEAAYENVKIHMQIFGSENRV
EEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA