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The map label for this gene is kstR2 [H]

Identifier: 118477866

GI number: 118477866

Start: 2363100

End: 2363594

Strand: Direct

Name: kstR2 [H]

Synonym: BALH_2210

Alternate gene names: 118477866

Gene position: 2363100-2363594 (Clockwise)

Preceding gene: 118477864

Following gene: 118477867

Centisome position: 44.95

GC content: 30.3

Gene sequence:

>495_bases
ATGCGAATAATTAAGGAGTATGAGGAACGTAGAAAAGAAATTTTAGAAACGGCTGAACGATTATTTCTTACGAAAGGTTA
TACGAAAACAACAGTAAATGACATTTTAAAAGAGATAGGGATAGCAAAGGGGACGTTTTATCATTATTTTAAATCGAAAG
AAGAAGTAATGGATGAGATTATTATGAGGATTATTAAAGAAGATGTTGCTAAAGCGAAAGTAATCGTCTCTAATCCAAAT
ATACCAGTATTAGAAAAGTTATTTCGAGTTTTAATGGAGCAATCTCCAAAATCAGGTGATATAAAAGATAAAATGATTGA
GCAATTTCATCAACCAAATAATGCAGAAATGCATCAAAAAAGTTTAGTGCAATCTATTATTCATTTATCTCCTGTATTAA
CAGAAATTTTAGAACAAGGAATTGAAGAAGGGATATTTTCGACTTCATATCCACAAGAAACGATTGAACTATTACTATCT
TCAGCGCAAGTTTGA

Upstream 100 bases:

>100_bases
GAAGTAGGACGTTGTATATGTATAAAATAGGAAACTTTTTACTAATTAAACATATAATTAAAATAGACCGACAGTCGGTC
TGGTTGGAAGGAGAACGTGA

Downstream 100 bases:

>100_bases
CTATGAAAGGTTTTACCTCAATGGTTCATAGCTAGAGAGCTTTAACCTATGTAGTCATTCTATAAGAGGTACTACCTACA
AGTCAATAACAATGTAGAAT

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MRIIKEYEERRKEILETAERLFLTKGYTKTTVNDILKEIGIAKGTFYHYFKSKEEVMDEIIMRIIKEDVAKAKVIVSNPN
IPVLEKLFRVLMEQSPKSGDIKDKMIEQFHQPNNAEMHQKSLVQSIIHLSPVLTEILEQGIEEGIFSTSYPQETIELLLS
SAQV

Sequences:

>Translated_164_residues
MRIIKEYEERRKEILETAERLFLTKGYTKTTVNDILKEIGIAKGTFYHYFKSKEEVMDEIIMRIIKEDVAKAKVIVSNPN
IPVLEKLFRVLMEQSPKSGDIKDKMIEQFHQPNNAEMHQKSLVQSIIHLSPVLTEILEQGIEEGIFSTSYPQETIELLLS
SAQV
>Mature_164_residues
MRIIKEYEERRKEILETAERLFLTKGYTKTTVNDILKEIGIAKGTFYHYFKSKEEVMDEIIMRIIKEDVAKAKVIVSNPN
IPVLEKLFRVLMEQSPKSGDIKDKMIEQFHQPNNAEMHQKSLVQSIIHLSPVLTEILEQGIEEGIFSTSYPQETIELLLS
SAQV

Specific function: Controls the expression of a small regulon that may play a role in the utilization of cholesterol [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 18981; Mature: 18981

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIKEYEERRKEILETAERLFLTKGYTKTTVNDILKEIGIAKGTFYHYFKSKEEVMDEI
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHH
IMRIIKEDVAKAKVIVSNPNIPVLEKLFRVLMEQSPKSGDIKDKMIEQFHQPNNAEMHQK
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHH
SLVQSIIHLSPVLTEILEQGIEEGIFSTSYPQETIELLLSSAQV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRIIKEYEERRKEILETAERLFLTKGYTKTTVNDILKEIGIAKGTFYHYFKSKEEVMDEI
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHH
IMRIIKEDVAKAKVIVSNPNIPVLEKLFRVLMEQSPKSGDIKDKMIEQFHQPNNAEMHQK
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHH
SLVQSIIHLSPVLTEILEQGIEEGIFSTSYPQETIELLLSSAQV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]