Click here to switch to the map view.

The map label for this gene is asd [H]

Identifier: 118477826

GI number: 118477826

Start: 2319696

End: 2320739

Strand: Direct

Name: asd [H]

Synonym: BALH_2166

Alternate gene names: 118477826

Gene position: 2319696-2320739 (Clockwise)

Preceding gene: 118477824

Following gene: 118477827

Centisome position: 44.13

GC content: 38.22

Gene sequence:

>1044_bases
ATGAGTGAAAAGGGCTATCATGTAGCTGTTGTTGGGGCTACGGGTGCAGTAGGTCAGAAAATTATTGAACTGTTAGAAAA
AGAAACAAAGTTTAATATAACTGAAGTTACGTTACTTTCGTCAAAAAGATCGGCTGGTAAGACAGTACAATTTAAAGGGC
GAGAGACCATTATACAAGAAGCAAAAATAAATAGCTTTGAAGGGGTAGATATTGCCTTTTTTAGCGCTGGGGGAGAAGTT
TCTAGACAATTTGTAAATCAAGTTGTCTCTAGTGGTGCAATCGTCATTGACAACACAAGTGAATACCGAATGGCACATGA
TGTACCGCTCGTTGTTCCGGAAGTGAATGCGCACACTTTAAAGGAACATAAAGGGATAATAGCAGTTCCGAATTGTTCAG
CATTACAGATGGTAACAGCTCTTCAGCCAATACGAAAAGTATTCGGATTAGAACGAATTATCGTTTCCACTTATCAGGCT
GTATCGGGTTCTGGTATTCATGCAATTCAAGAATTAAAAGAACAGGCTAAGTCAATACTTGCAGGTGAAGAAGTGGAGAG
TACTATATTACCAGCGAAAAAAGATAAAAAACATTATCCAATTGCATTTAATGTACTCCCTCAAGTAGATATATTCACGG
ATAATGATTTCACCTTTGAAGAAGTAAAGATGATACAAGAAACGAAGAAAATTTTAGAAGACCCAAACTTGAAAATGGCA
GCTACTTGTGTGCGTGTTCCGGTCATATCAGGTCACTCAGAATCGGTTTATATAGAGCTTGAAAAAGAAGCAACTGTTGC
AGAAATTAAAGAAGTATTGTTTGATGCACCAGGTGTTATTTTGCAGGATAACCCTAGTGAACAGCTGTATCCAATGCCAT
TATACGCAGAAGGGAAAATAGATACATTTGTCGGTAGAATTAGAAAAGATCCTGATACACCAAACGGATTCCATCTTTGG
ATCGTTTCCGATAATTTATTAAAAGGTGCGGCGTGGAACTCGGTGCAAATTGCAGAAACGATGGTGGAAGAGGGAATCAT
TTAG

Upstream 100 bases:

>100_bases
GTGAATGATTATATCACGTATTTCAATTTTCCAAATGATTAAATTCCTTATAAAATGAAATTGTAGAAATATTTATTCAT
TTAATATTGGAGGAGAAAAG

Downstream 100 bases:

>100_bases
TATTAAGGAAACTAGGGAACTGTTAAAGATTACAGTTTCCTAGTTTTTATTTTATAACTGTTCGCTTTATTCCAGCCGTA
TTTAATTTGAGAGACAGTAA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSEKGYHVAVVGATGAVGQKIIELLEKETKFNITEVTLLSSKRSAGKTVQFKGRETIIQEAKINSFEGVDIAFFSAGGEV
SRQFVNQVVSSGAIVIDNTSEYRMAHDVPLVVPEVNAHTLKEHKGIIAVPNCSALQMVTALQPIRKVFGLERIIVSTYQA
VSGSGIHAIQELKEQAKSILAGEEVESTILPAKKDKKHYPIAFNVLPQVDIFTDNDFTFEEVKMIQETKKILEDPNLKMA
ATCVRVPVISGHSESVYIELEKEATVAEIKEVLFDAPGVILQDNPSEQLYPMPLYAEGKIDTFVGRIRKDPDTPNGFHLW
IVSDNLLKGAAWNSVQIAETMVEEGII

Sequences:

>Translated_347_residues
MSEKGYHVAVVGATGAVGQKIIELLEKETKFNITEVTLLSSKRSAGKTVQFKGRETIIQEAKINSFEGVDIAFFSAGGEV
SRQFVNQVVSSGAIVIDNTSEYRMAHDVPLVVPEVNAHTLKEHKGIIAVPNCSALQMVTALQPIRKVFGLERIIVSTYQA
VSGSGIHAIQELKEQAKSILAGEEVESTILPAKKDKKHYPIAFNVLPQVDIFTDNDFTFEEVKMIQETKKILEDPNLKMA
ATCVRVPVISGHSESVYIELEKEATVAEIKEVLFDAPGVILQDNPSEQLYPMPLYAEGKIDTFVGRIRKDPDTPNGFHLW
IVSDNLLKGAAWNSVQIAETMVEEGII
>Mature_346_residues
SEKGYHVAVVGATGAVGQKIIELLEKETKFNITEVTLLSSKRSAGKTVQFKGRETIIQEAKINSFEGVDIAFFSAGGEVS
RQFVNQVVSSGAIVIDNTSEYRMAHDVPLVVPEVNAHTLKEHKGIIAVPNCSALQMVTALQPIRKVFGLERIIVSTYQAV
SGSGIHAIQELKEQAKSILAGEEVESTILPAKKDKKHYPIAFNVLPQVDIFTDNDFTFEEVKMIQETKKILEDPNLKMAA
TCVRVPVISGHSESVYIELEKEATVAEIKEVLFDAPGVILQDNPSEQLYPMPLYAEGKIDTFVGRIRKDPDTPNGFHLWI
VSDNLLKGAAWNSVQIAETMVEEGII

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=348, Percent_Identity=33.0459770114943, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1789841, Length=361, Percent_Identity=25.4847645429363, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320362, Length=399, Percent_Identity=28.0701754385965, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38162; Mature: 38031

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKGYHVAVVGATGAVGQKIIELLEKETKFNITEVTLLSSKRSAGKTVQFKGRETIIQE
CCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCHHHHHHH
AKINSFEGVDIAFFSAGGEVSRQFVNQVVSSGAIVIDNTSEYRMAHDVPLVVPEVNAHTL
HCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCEEEECCCEEEEECCCCHHH
KEHKGIIAVPNCSALQMVTALQPIRKVFGLERIIVSTYQAVSGSGIHAIQELKEQAKSIL
HHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AGEEVESTILPAKKDKKHYPIAFNVLPQVDIFTDNDFTFEEVKMIQETKKILEDPNLKMA
CCCHHHHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEE
ATCVRVPVISGHSESVYIELEKEATVAEIKEVLFDAPGVILQDNPSEQLYPMPLYAEGKI
EEEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEECCCCCCEECCCEEECCCH
DTFVGRIRKDPDTPNGFHLWIVSDNLLKGAAWNSVQIAETMVEEGII
HHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SEKGYHVAVVGATGAVGQKIIELLEKETKFNITEVTLLSSKRSAGKTVQFKGRETIIQE
CCCCEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCHHHHHHH
AKINSFEGVDIAFFSAGGEVSRQFVNQVVSSGAIVIDNTSEYRMAHDVPLVVPEVNAHTL
HCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCEEEECCCEEEEECCCCHHH
KEHKGIIAVPNCSALQMVTALQPIRKVFGLERIIVSTYQAVSGSGIHAIQELKEQAKSIL
HHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
AGEEVESTILPAKKDKKHYPIAFNVLPQVDIFTDNDFTFEEVKMIQETKKILEDPNLKMA
CCCHHHHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEE
ATCVRVPVISGHSESVYIELEKEATVAEIKEVLFDAPGVILQDNPSEQLYPMPLYAEGKI
EEEEEEEEECCCCCEEEEEEECCCHHHHHHHHHHCCCCEEEECCCCCCEECCCEEECCCH
DTFVGRIRKDPDTPNGFHLWIVSDNLLKGAAWNSVQIAETMVEEGII
HHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377; 8345520 [H]