BacMap

Definition	Bacillus thuringiensis str. Al Hakam chromosome, complete genome.
Accession	NC_008600
Length	5,257,091

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The map label for this gene is iolA1

Identifier: 118477760

GI number: 118477760

Start: 2245593

End: 2247053

Strand: Direct

Name: iolA1

Synonym: BALH_2098

Alternate gene names: 118477760

Gene position: 2245593-2247053 (Clockwise)

Preceding gene: 118477759

Following gene: 118477763

Centisome position: 42.72

GC content: 38.47

Gene sequence:

>1461_bases
ATGATTACAACTGAAATTAAACGAGTAAAAAATCATATTAATGGTGAGTGGGTAGAATCTACTGGTACAGAAGTAGAAGC
AGTTCCAAATCCGGCGACTGGAAAAATTATCGCTTACGTTCCGCTATCTCCGAAAGAAGATGTTGAAAAAGCTGTTGAAG
CAGCAAAAGCAGCATATGAAACATGGTCTAAAGTACCAGTTCCGAATCGTTCAAGACAATTGTATAAATATTTACAGCTT
TTACAAGAAAATAAAGAAGAACTGGCAAAAATTATTACGCTAGAAAATGGTAAAACATTAACGGATGCAACTGGTGAAGT
GCAGCGTGGTATTGAAGCGGTAGAACTAGCAACATCTACGCCAAATTTAATGATGGGACAAGCACTTCCGAATATTGCTA
GTGGCATTGATGGATCAATTTGGCGCTATCCAATCGGGGTTGTTGCTGGTATTACACCTTTTAACTTCCCAATGATGATT
CCATTATGGATGTTCCCTCTTGCAATTGCTTGTGGTAATACATTCGTATTAAAAACATCTGAAAGAACGCCGCTTTTGGC
TGAAAGACTTGTAGAGTTATTCTATGAAGCTGGTTTTCCAAAAGGCGTACTAAATTTAGTACAAGGCGGAAAAGATGTTG
TAAATAGCATTTTAGAAAATAAAGATATTCAAGCTGTTTCGTTCGTTGGATCTGAGCCGGTAGCTCGTTACGTATACGAA
ACAGGTACAAAACATGGAAAACGTGTACAAGCGTTAGCTGGTGCGAAAAACCACGCGATTGTAATGCCAGATTGCAATCT
TGAGAAAACAGTGCAAGGTGTAATTGGATCCGCATTTGCAAGTAGCGGAGAACGCTGCATGGCATGTTCAGTAGTAGCGG
TAGTTGATGAAATTGCTGATGAATTCATTGACGTACTAGTAGCAGAGACGAAGAAGTTAAAAGTAGGTGACGGTTTCCAC
GAAGATAATTATGTTGGACCATTAATTCGTGAATCTCATAAAGAGCGTGTATTAGGCTATATTAATAGCGGTGTAGCAGA
TGGAGCAACGTTATTAGTAGATGGCCGCAAAATTAAGGAAGAAGTTGGAGAAGGTTACTTTGTAGGTGCGACAATCTTTG
ATGGCGTAAATCAAGAAATGAAAATTTGGCAAGATGAAATTTTCGCTCCAGTATTAAGCATTGTCCGTGTTAAAGATTTA
GAAGAAGGTATTAAACTAACAAATCAATCTAAATTTGCAAATGGTGCGGTTATTTATACGTCAAACGGTAAACATGCACA
AACGTTCCGTGATAACATCGATGCGGGTATGATCGGTGTAAACGTAAACGTTCCAGCACCAATGGCATTCTTCGCATTTG
CAGGAAATAAAGCTTCATTCTTTGGTGATTTAGGTACAAATGGTACAGATGGTGTTCAATTCTATACACGTAAAAAAGTT
GTAACTGAGCGCTGGTTTTAA

Upstream 100 bases:

>100_bases
TGAAAATGATATGGCTGCTTTATATAAAAAAGTTAGTGAACAATTAATTTCTAATCAAAAATAATAGACTTATAAACATC
ATAAAAAAGGAGAGAATATA

Downstream 100 bases:

>100_bases
TAAAGAGTAAACAGTCAAATCAGTTATTAAATGAAAACCACCACTAGAAATAGTGGTGGTTTTCGTTTTGTTAATTACTT
TTTTCAAAAGCAAGTTTAAT

Product: methylmalonate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: MMSA dehydrogenase 1; MMSDH 1; MSDH 1; Malonate semialdehyde dehydrogenase [acetylating] 1; MSA dehydrogenase 1

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MITTEIKRVKNHINGEWVESTGTEVEAVPNPATGKIIAYVPLSPKEDVEKAVEAAKAAYETWSKVPVPNRSRQLYKYLQL
LQENKEELAKIITLENGKTLTDATGEVQRGIEAVELATSTPNLMMGQALPNIASGIDGSIWRYPIGVVAGITPFNFPMMI
PLWMFPLAIACGNTFVLKTSERTPLLAERLVELFYEAGFPKGVLNLVQGGKDVVNSILENKDIQAVSFVGSEPVARYVYE
TGTKHGKRVQALAGAKNHAIVMPDCNLEKTVQGVIGSAFASSGERCMACSVVAVVDEIADEFIDVLVAETKKLKVGDGFH
EDNYVGPLIRESHKERVLGYINSGVADGATLLVDGRKIKEEVGEGYFVGATIFDGVNQEMKIWQDEIFAPVLSIVRVKDL
EEGIKLTNQSKFANGAVIYTSNGKHAQTFRDNIDAGMIGVNVNVPAPMAFFAFAGNKASFFGDLGTNGTDGVQFYTRKKV
VTERWF

Sequences:

>Translated_486_residues
MITTEIKRVKNHINGEWVESTGTEVEAVPNPATGKIIAYVPLSPKEDVEKAVEAAKAAYETWSKVPVPNRSRQLYKYLQL
LQENKEELAKIITLENGKTLTDATGEVQRGIEAVELATSTPNLMMGQALPNIASGIDGSIWRYPIGVVAGITPFNFPMMI
PLWMFPLAIACGNTFVLKTSERTPLLAERLVELFYEAGFPKGVLNLVQGGKDVVNSILENKDIQAVSFVGSEPVARYVYE
TGTKHGKRVQALAGAKNHAIVMPDCNLEKTVQGVIGSAFASSGERCMACSVVAVVDEIADEFIDVLVAETKKLKVGDGFH
EDNYVGPLIRESHKERVLGYINSGVADGATLLVDGRKIKEEVGEGYFVGATIFDGVNQEMKIWQDEIFAPVLSIVRVKDL
EEGIKLTNQSKFANGAVIYTSNGKHAQTFRDNIDAGMIGVNVNVPAPMAFFAFAGNKASFFGDLGTNGTDGVQFYTRKKV
VTERWF
>Mature_486_residues
MITTEIKRVKNHINGEWVESTGTEVEAVPNPATGKIIAYVPLSPKEDVEKAVEAAKAAYETWSKVPVPNRSRQLYKYLQL
LQENKEELAKIITLENGKTLTDATGEVQRGIEAVELATSTPNLMMGQALPNIASGIDGSIWRYPIGVVAGITPFNFPMMI
PLWMFPLAIACGNTFVLKTSERTPLLAERLVELFYEAGFPKGVLNLVQGGKDVVNSILENKDIQAVSFVGSEPVARYVYE
TGTKHGKRVQALAGAKNHAIVMPDCNLEKTVQGVIGSAFASSGERCMACSVVAVVDEIADEFIDVLVAETKKLKVGDGFH
EDNYVGPLIRESHKERVLGYINSGVADGATLLVDGRKIKEEVGEGYFVGATIFDGVNQEMKIWQDEIFAPVLSIVRVKDL
EEGIKLTNQSKFANGAVIYTSNGKHAQTFRDNIDAGMIGVNVNVPAPMAFFAFAGNKASFFGDLGTNGTDGVQFYTRKKV
VTERWF

Specific function: Converts malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. IolA subfamily

Homologues:

Organism=Homo sapiens, GI11095441, Length=481, Percent_Identity=44.6985446985447, Blast_Score=442, Evalue=1e-124,
Organism=Homo sapiens, GI25777730, Length=484, Percent_Identity=32.0247933884297, Blast_Score=244, Evalue=1e-64,
Organism=Homo sapiens, GI25777732, Length=484, Percent_Identity=31.8181818181818, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI115387104, Length=476, Percent_Identity=31.3025210084034, Blast_Score=239, Evalue=4e-63,
Organism=Homo sapiens, GI21361176, Length=492, Percent_Identity=32.9268292682927, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI153266822, Length=463, Percent_Identity=33.2613390928726, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI25777724, Length=492, Percent_Identity=32.1138211382114, Blast_Score=229, Evalue=6e-60,
Organism=Homo sapiens, GI12007648, Length=492, Percent_Identity=29.8780487804878, Blast_Score=221, Evalue=9e-58,
Organism=Homo sapiens, GI238814322, Length=485, Percent_Identity=31.340206185567, Blast_Score=218, Evalue=1e-56,
Organism=Homo sapiens, GI21614513, Length=485, Percent_Identity=32.5773195876289, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI25777726, Length=490, Percent_Identity=29.7959183673469, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI25777728, Length=424, Percent_Identity=31.1320754716981, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI4507229, Length=471, Percent_Identity=29.2993630573248, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI25777721, Length=484, Percent_Identity=28.3057851239669, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI188035924, Length=479, Percent_Identity=26.7223382045929, Blast_Score=168, Evalue=9e-42,
Organism=Homo sapiens, GI25952152, Length=488, Percent_Identity=26.0245901639344, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI310128103, Length=475, Percent_Identity=26.7368421052632, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI310128093, Length=473, Percent_Identity=27.061310782241, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI310128091, Length=472, Percent_Identity=25.635593220339, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI301500698, Length=289, Percent_Identity=29.0657439446367, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI310128087, Length=277, Percent_Identity=27.4368231046931, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI206597441, Length=404, Percent_Identity=24.7524752475248, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI206597439, Length=404, Percent_Identity=24.7524752475248, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI22907049, Length=404, Percent_Identity=24.7524752475248, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI238859541, Length=398, Percent_Identity=24.3718592964824, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI25777736, Length=398, Percent_Identity=24.3718592964824, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI25777734, Length=398, Percent_Identity=24.3718592964824, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI310128099, Length=229, Percent_Identity=28.3842794759825, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI310128101, Length=229, Percent_Identity=28.3842794759825, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4557303, Length=429, Percent_Identity=22.6107226107226, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI73466520, Length=429, Percent_Identity=22.6107226107226, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI73695881, Length=307, Percent_Identity=25.4071661237785, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI73695879, Length=307, Percent_Identity=25.4071661237785, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4502043, Length=366, Percent_Identity=25.4098360655738, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI238814371, Length=366, Percent_Identity=25.4098360655738, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI310128089, Length=287, Percent_Identity=25.7839721254355, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI71773324, Length=284, Percent_Identity=25.3521126760563, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI310128095, Length=316, Percent_Identity=24.3670886075949, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI310128097, Length=249, Percent_Identity=25.3012048192771, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI223972651, Length=445, Percent_Identity=21.7977528089888, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI87081896, Length=475, Percent_Identity=30.9473684210526, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1789015, Length=464, Percent_Identity=31.25, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1787558, Length=435, Percent_Identity=30.8045977011494, Blast_Score=205, Evalue=6e-54,
Organism=Escherichia coli, GI1786504, Length=474, Percent_Identity=30.8016877637131, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI87082295, Length=465, Percent_Identity=29.8924731182796, Blast_Score=194, Evalue=9e-51,
Organism=Escherichia coli, GI1787684, Length=472, Percent_Identity=30.5084745762712, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI87081926, Length=439, Percent_Identity=28.4738041002278, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1787715, Length=433, Percent_Identity=30.2540415704388, Blast_Score=171, Evalue=7e-44,
Organism=Escherichia coli, GI1788042, Length=405, Percent_Identity=28.641975308642, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1787250, Length=434, Percent_Identity=28.5714285714286, Blast_Score=150, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71986308, Length=478, Percent_Identity=44.7698744769874, Blast_Score=430, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI17562198, Length=481, Percent_Identity=33.2640332640333, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI133930964, Length=468, Percent_Identity=31.6239316239316, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI25143874, Length=489, Percent_Identity=29.2433537832311, Blast_Score=212, Evalue=4e-55,
Organism=Caenorhabditis elegans, GI25143876, Length=489, Percent_Identity=29.2433537832311, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI25144435, Length=485, Percent_Identity=31.5463917525773, Blast_Score=203, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17534119, Length=471, Percent_Identity=28.4501061571125, Blast_Score=189, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17551164, Length=463, Percent_Identity=30.0215982721382, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI32564736, Length=426, Percent_Identity=31.2206572769953, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI71995606, Length=488, Percent_Identity=29.5081967213115, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI115534176, Length=480, Percent_Identity=28.125, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71995613, Length=421, Percent_Identity=30.166270783848, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17564084, Length=450, Percent_Identity=26, Blast_Score=115, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI32566756, Length=450, Percent_Identity=25.1111111111111, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI25146391, Length=450, Percent_Identity=25.1111111111111, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI25146394, Length=450, Percent_Identity=25.1111111111111, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17534447, Length=368, Percent_Identity=24.7282608695652, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32564151, Length=368, Percent_Identity=24.7282608695652, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115532534, Length=264, Percent_Identity=26.8939393939394, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71990744, Length=284, Percent_Identity=24.6478873239437, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324950, Length=475, Percent_Identity=32.6315789473684, Blast_Score=246, Evalue=7e-66,
Organism=Saccharomyces cerevisiae, GI6320917, Length=441, Percent_Identity=31.9727891156463, Blast_Score=219, Evalue=9e-58,
Organism=Saccharomyces cerevisiae, GI6323822, Length=475, Percent_Identity=32.6315789473684, Blast_Score=217, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6323821, Length=479, Percent_Identity=31.9415448851775, Blast_Score=204, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6325196, Length=434, Percent_Identity=30.184331797235, Blast_Score=203, Evalue=6e-53,
Organism=Saccharomyces cerevisiae, GI6319478, Length=478, Percent_Identity=28.0334728033473, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6321828, Length=462, Percent_Identity=26.1904761904762, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6321826, Length=416, Percent_Identity=25.9615384615385, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323757, Length=399, Percent_Identity=25.062656641604, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24638878, Length=474, Percent_Identity=44.3037974683544, Blast_Score=401, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24638876, Length=477, Percent_Identity=44.2348008385744, Blast_Score=401, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24650465, Length=484, Percent_Identity=34.0909090909091, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI281362580, Length=467, Percent_Identity=31.6916488222698, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI62472918, Length=467, Percent_Identity=31.6916488222698, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI62472926, Length=467, Percent_Identity=31.6916488222698, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI62472936, Length=467, Percent_Identity=31.6916488222698, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI21356737, Length=467, Percent_Identity=31.6916488222698, Blast_Score=236, Evalue=3e-62,
Organism=Drosophila melanogaster, GI20129399, Length=482, Percent_Identity=33.6099585062241, Blast_Score=231, Evalue=6e-61,
Organism=Drosophila melanogaster, GI24585660, Length=484, Percent_Identity=30.3719008264463, Blast_Score=224, Evalue=8e-59,
Organism=Drosophila melanogaster, GI24666674, Length=483, Percent_Identity=27.7432712215321, Blast_Score=179, Evalue=5e-45,
Organism=Drosophila melanogaster, GI24668425, Length=423, Percent_Identity=26.0047281323877, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24668417, Length=423, Percent_Identity=26.0047281323877, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24668413, Length=423, Percent_Identity=26.0047281323877, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281360303, Length=349, Percent_Identity=23.7822349570201, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45552499, Length=349, Percent_Identity=23.7822349570201, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281360301, Length=349, Percent_Identity=24.0687679083095, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281360299, Length=349, Percent_Identity=24.0687679083095, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281360297, Length=349, Percent_Identity=24.0687679083095, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281360295, Length=349, Percent_Identity=24.0687679083095, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24586250, Length=349, Percent_Identity=24.0687679083095, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28571806, Length=416, Percent_Identity=22.8365384615385, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571802, Length=416, Percent_Identity=22.8365384615385, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571800, Length=416, Percent_Identity=22.8365384615385, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571798, Length=416, Percent_Identity=22.8365384615385, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571796, Length=416, Percent_Identity=22.8365384615385, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571794, Length=416, Percent_Identity=22.8365384615385, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IOLA1_BACAH (A0RDW1)

Other databases:

- EMBL:   CP000485
- RefSeq:   YP_894911.1
- ProteinModelPortal:   A0RDW1
- SMR:   A0RDW1
- STRING:   A0RDW1
- EnsemblBacteria:   EBBACT00000068914
- GeneID:   4545461
- GenomeReviews:   CP000485_GR
- KEGG:   btl:BALH_2098
- eggNOG:   COG1012
- GeneTree:   EBGT00070000031871
- HOGENOM:   HBG752218
- OMA:   NGAGVDM
- ProtClustDB:   CLSK873284
- BioCyc:   BTHU412694:BALH_2098-MONOMER
- HAMAP:   MF_01670
- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR010061
- Gene3D:   G3DSA:3.40.309.10
- Gene3D:   G3DSA:3.40.605.10
- PANTHER:   PTHR11699
- PANTHER:   PTHR11699:SF27
- TIGRFAMs:   TIGR01722

Pfam domain/function: PF00171 Aldedh; SSF53720 Aldehyde_DH/Histidinol_DH

EC number: =1.2.1.27; =1.2.1.18

Molecular weight: Translated: 53005; Mature: 53005

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS; PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: ACT_SITE 286-286 BINDING 386-386

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTEIKRVKNHINGEWVESTGTEVEAVPNPATGKIIAYVPLSPKEDVEKAVEAAKAAYE
CCCHHHHHHHHHCCCCEEECCCCEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
TWSKVPVPNRSRQLYKYLQLLQENKEELAKIITLENGKTLTDATGEVQRGIEAVELATST
HHHCCCCCCCHHHHHHHHHHHHHCHHHHHHHEEECCCCEECCCCHHHHHCHHHHHEECCC
PNLMMGQALPNIASGIDGSIWRYPIGVVAGITPFNFPMMIPLWMFPLAIACGNTFVLKTS
CCHHHHHHCCHHHCCCCCCHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEC
ERTPLLAERLVELFYEAGFPKGVLNLVQGGKDVVNSILENKDIQAVSFVGSEPVARYVYE
CCCCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
TGTKHGKRVQALAGAKNHAIVMPDCNLEKTVQGVIGSAFASSGERCMACSVVAVVDEIAD
HCCCCCCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EFIDVLVAETKKLKVGDGFHEDNYVGPLIRESHKERVLGYINSGVADGATLLVDGRKIKE
HHHHHHHHHCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHH
EVGEGYFVGATIFDGVNQEMKIWQDEIFAPVLSIVRVKDLEEGIKLTNQSKFANGAVIYT
HHCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
SNGKHAQTFRDNIDAGMIGVNVNVPAPMAFFAFAGNKASFFGDLGTNGTDGVQFYTRKKV
CCCCCHHHHHCCCCCCEEEEEECCCCCCEEEEECCCCCEEEECCCCCCCCCCEEHHHHHH
VTERWF
HHHCCC
>Mature Secondary Structure
MITTEIKRVKNHINGEWVESTGTEVEAVPNPATGKIIAYVPLSPKEDVEKAVEAAKAAYE
CCCHHHHHHHHHCCCCEEECCCCEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
TWSKVPVPNRSRQLYKYLQLLQENKEELAKIITLENGKTLTDATGEVQRGIEAVELATST
HHHCCCCCCCHHHHHHHHHHHHHCHHHHHHHEEECCCCEECCCCHHHHHCHHHHHEECCC
PNLMMGQALPNIASGIDGSIWRYPIGVVAGITPFNFPMMIPLWMFPLAIACGNTFVLKTS
CCHHHHHHCCHHHCCCCCCHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEC
ERTPLLAERLVELFYEAGFPKGVLNLVQGGKDVVNSILENKDIQAVSFVGSEPVARYVYE
CCCCHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHH
TGTKHGKRVQALAGAKNHAIVMPDCNLEKTVQGVIGSAFASSGERCMACSVVAVVDEIAD
HCCCCCCHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
EFIDVLVAETKKLKVGDGFHEDNYVGPLIRESHKERVLGYINSGVADGATLLVDGRKIKE
HHHHHHHHHCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHH
EVGEGYFVGATIFDGVNQEMKIWQDEIFAPVLSIVRVKDLEEGIKLTNQSKFANGAVIYT
HHCCCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEE
SNGKHAQTFRDNIDAGMIGVNVNVPAPMAFFAFAGNKASFFGDLGTNGTDGVQFYTRKKV
CCCCCHHHHHCCCCCCEEEEEECCCCCCEEEEECCCCCEEEECCCCCCCCCCEEHHHHHH
VTERWF
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA