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The map label for this gene is kinA [H]

Identifier: 118477717

GI number: 118477717

Start: 2202327

End: 2203460

Strand: Direct

Name: kinA [H]

Synonym: BALH_2054

Alternate gene names: 118477717

Gene position: 2202327-2203460 (Clockwise)

Preceding gene: 118477715

Following gene: 118477719

Centisome position: 41.89

GC content: 31.04

Gene sequence:

>1134_bases
ATGGAAATGGAGGGAATGGAGGTTTTTCCAATCGATAAGGATATTAAAGAAGTATTTTGTTCGCACTTGAAAAACAACAG
GCACCAATTCGTTGAGAACTGGAAAAACAAAATGATAATTTCCGATAAAGATCCATTTAGACTAGAAGTAGTTCAAAATG
GAGAGGATTTATTAGAGTTTATTATTGAACTTATTATGGAAGAAAAAGATATTAATTATCTTCAGCCATTATGCGAGAAA
ATTGCTATTGAACGTGCAGGAGCAGATGCTAATATAGGTGATTTTGTTTATAATGCAAATGTGGGAAGAAATGAGCTTTT
CGAAGCGATGTGTGAATTAGATGTTAGTGCACGTGAATTGAAACCAATTATGAACCAAATACATACTTGTTTTGACAAAT
TAATTTATTATACTGTTTTAAAATACTCGGAAATTATATCAAGAAACTTAGAGGAAAAACAGCAATATATTAACGAAACA
CATAAAGAAAGGCTGACGATTTTAGGGCAAATGTCAGCTAGTTTTGTACACGAATTTCGTAATCCGCTTACTTCCATTAT
GGGATTTGTCAAATTATTAAAGGCAGATCATCCTAGTTTATCGTATTTAGATATTATTTCTCATGAATTAGACCAATTAA
ATTTTCGTATTTCGCAATTTTTACTCGTATCGAAAAAGGAAATGTGGAATGAATCAGAAAGTTTTTGGCTTAATGACTTG
TTTCAAGATATTATACAGTTCTTATATCCGAGTTTGGTCAATGCAAATGTTTCGATTGAAAAGAATTTGCCATATCCAAT
TCCGCTTACTGGTTATCGGAGTGAAGTGAGACAAGTATTTTTAAATATATTAATGAACTCAATTGACGCTCTTGAATCAA
TGAAAGAAGAACGGAAAATTATCATTGATGTATTTGAAGAAGATCAATCGATTCGAATTGTAATAAAAAATAATGGGCCA
ATGATTCCAGCTGAAAATGTAGAAACGATTTTTGAACCATTTGTAACTACTAAAAAGCTAGGAACTGGTATTGGATTATT
TGTATGTAAACAAATTGTAGAAAAACATAATGGGTCCATCATGTGTCGTTCAGATAACGATTGGACAGAATTTCAAATTG
CATTTCAAAAATAA

Upstream 100 bases:

>100_bases
ATAAAAATTTTATCAACACATATTAACAAAATGTGACAATAATCTATTAACGAATCATGATTTTTGTGTTAATATTCAAA
ATATAAAGGGTATTCGTCGC

Downstream 100 bases:

>100_bases
ACAGTCTACACCAAATGAATGGTGTAGACTGTTTAATTCGTAAGTATAACGGCTTCTAATTTAGGGTCTTTCATTGAATA
ACCTAAAAGTGAAATTGTAT

Product: sensor histidine kinase, sporulation kinase A

Products: NA

Alternate protein names: Stage II sporulation protein F; Stage II sporulation protein J [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MEMEGMEVFPIDKDIKEVFCSHLKNNRHQFVENWKNKMIISDKDPFRLEVVQNGEDLLEFIIELIMEEKDINYLQPLCEK
IAIERAGADANIGDFVYNANVGRNELFEAMCELDVSARELKPIMNQIHTCFDKLIYYTVLKYSEIISRNLEEKQQYINET
HKERLTILGQMSASFVHEFRNPLTSIMGFVKLLKADHPSLSYLDIISHELDQLNFRISQFLLVSKKEMWNESESFWLNDL
FQDIIQFLYPSLVNANVSIEKNLPYPIPLTGYRSEVRQVFLNILMNSIDALESMKEERKIIIDVFEEDQSIRIVIKNNGP
MIPAENVETIFEPFVTTKKLGTGIGLFVCKQIVEKHNGSIMCRSDNDWTEFQIAFQK

Sequences:

>Translated_377_residues
MEMEGMEVFPIDKDIKEVFCSHLKNNRHQFVENWKNKMIISDKDPFRLEVVQNGEDLLEFIIELIMEEKDINYLQPLCEK
IAIERAGADANIGDFVYNANVGRNELFEAMCELDVSARELKPIMNQIHTCFDKLIYYTVLKYSEIISRNLEEKQQYINET
HKERLTILGQMSASFVHEFRNPLTSIMGFVKLLKADHPSLSYLDIISHELDQLNFRISQFLLVSKKEMWNESESFWLNDL
FQDIIQFLYPSLVNANVSIEKNLPYPIPLTGYRSEVRQVFLNILMNSIDALESMKEERKIIIDVFEEDQSIRIVIKNNGP
MIPAENVETIFEPFVTTKKLGTGIGLFVCKQIVEKHNGSIMCRSDNDWTEFQIAFQK
>Mature_377_residues
MEMEGMEVFPIDKDIKEVFCSHLKNNRHQFVENWKNKMIISDKDPFRLEVVQNGEDLLEFIIELIMEEKDINYLQPLCEK
IAIERAGADANIGDFVYNANVGRNELFEAMCELDVSARELKPIMNQIHTCFDKLIYYTVLKYSEIISRNLEEKQQYINET
HKERLTILGQMSASFVHEFRNPLTSIMGFVKLLKADHPSLSYLDIISHELDQLNFRISQFLLVSKKEMWNESESFWLNDL
FQDIIQFLYPSLVNANVSIEKNLPYPIPLTGYRSEVRQVFLNILMNSIDALESMKEERKIIIDVFEEDQSIRIVIKNNGP
MIPAENVETIFEPFVTTKKLGTGIGLFVCKQIVEKHNGSIMCRSDNDWTEFQIAFQK

Specific function: Phosphorylates the sporulation-regulatory proteins spo0A and spo0F. It also autophosphorylates in the presence of ATP [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=31.8725099601594, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=29.4642857142857, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1790300, Length=214, Percent_Identity=25.7009345794392, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=27.1493212669683, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790346, Length=195, Percent_Identity=25.6410256410256, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR013655
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF08447 PAS_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44031; Mature: 44031

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50109 HIS_KIN ; PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMEGMEVFPIDKDIKEVFCSHLKNNRHQFVENWKNKMIISDKDPFRLEVVQNGEDLLEF
CCCCCCEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCEEECCCCCCEEEEECCCHHHHHH
IIELIMEEKDINYLQPLCEKIAIERAGADANIGDFVYNANVGRNELFEAMCELDVSAREL
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHH
KPIMNQIHTCFDKLIYYTVLKYSEIISRNLEEKQQYINETHKERLTILGQMSASFVHEFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NPLTSIMGFVKLLKADHPSLSYLDIISHELDQLNFRISQFLLVSKKEMWNESESFWLNDL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FQDIIQFLYPSLVNANVSIEKNLPYPIPLTGYRSEVRQVFLNILMNSIDALESMKEERKI
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
IIDVFEEDQSIRIVIKNNGPMIPAENVETIFEPFVTTKKLGTGIGLFVCKQIVEKHNGSI
EEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCE
MCRSDNDWTEFQIAFQK
EEECCCCCEEEEEEECC
>Mature Secondary Structure
MEMEGMEVFPIDKDIKEVFCSHLKNNRHQFVENWKNKMIISDKDPFRLEVVQNGEDLLEF
CCCCCCEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCEEECCCCCCEEEEECCCHHHHHH
IIELIMEEKDINYLQPLCEKIAIERAGADANIGDFVYNANVGRNELFEAMCELDVSAREL
HHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHH
KPIMNQIHTCFDKLIYYTVLKYSEIISRNLEEKQQYINETHKERLTILGQMSASFVHEFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NPLTSIMGFVKLLKADHPSLSYLDIISHELDQLNFRISQFLLVSKKEMWNESESFWLNDL
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FQDIIQFLYPSLVNANVSIEKNLPYPIPLTGYRSEVRQVFLNILMNSIDALESMKEERKI
HHHHHHHHHHHHHCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
IIDVFEEDQSIRIVIKNNGPMIPAENVETIFEPFVTTKKLGTGIGLFVCKQIVEKHNGSI
EEEEECCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCE
MCRSDNDWTEFQIAFQK
EEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2104615; 2509430; 9384377 [H]