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The map label for this gene is yhcZ [H]

Identifier: 118477693

GI number: 118477693

Start: 2174638

End: 2175303

Strand: Direct

Name: yhcZ [H]

Synonym: BALH_2025

Alternate gene names: 118477693

Gene position: 2174638-2175303 (Clockwise)

Preceding gene: 118477692

Following gene: 118477694

Centisome position: 41.37

GC content: 36.49

Gene sequence:

>666_bases
TTGAAATTCAATTGCCGGTTTGAAGGGGGAAGAAGGTTGAAGATTAAATTATTACTAGTTGAGGATCATCATATCGTTCG
AAGAGGACTTGTATTCTTTTTGAAAACGAGAGAAGAATTTGAAATTGTTGGGGAAGCAGAAAATGGTGAAGATGCATTAA
CATTTGTTCGAACGGAAAGGCCAGATGTAGTATTAATGGATCTATCAATGCCGAAGATGGATGGTATTGAAGCAACAAAA
CAGATAAAACAATATGATGAAACAATAAAGATACTAATATTAAGCAGTTTTTCAGAGCAAGATTATGTTTTACCAGCACT
AGAAGCTGGAGCAGATGGTTATCAATTAAAAGAAGTACAACCTGAGCAACTTGTAGCTTCTATCATTGCAATATATGAAG
GGAATGCTAATTTTCATCCGAAAGTAACACCGGCACTATTAGGACGATCAGCCGTCAAAAAAGAAAACCCTTTCTCCATG
TTAACGAAAAGAGAGCAAGAAGTACTTCAGGAAATTGCGAAAGGGCGAAGCAATAAAGAAATTGCAGCAGAGCTTCATAT
TACAGAACAAACTGTGAAAACACATGTTTCAAATATTTTAGCTAAATTGGAAGTAGATGATCGTACGCAAGCTGCACTGT
ACGCAGTGAAACACGGCGAGAAATAA

Upstream 100 bases:

>100_bases
GTAAGAGAGTCAGCACTCGGTTTAAAAAGTATGAAGGAGCGTATTCAGTTATTGAATGGATCATTTCAAATAAAAACTGA
GCTGAAAAAGGGTACGAAAA

Downstream 100 bases:

>100_bases
TAAGTATGAATAACTGTGTCACTTATTATGACAGAATACATAGGAACAATTAAAAATTTATAGTAATGCTGAATAAAGGT
TTTTTCTTCTTTCAATAATT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MKFNCRFEGGRRLKIKLLLVEDHHIVRRGLVFFLKTREEFEIVGEAENGEDALTFVRTERPDVVLMDLSMPKMDGIEATK
QIKQYDETIKILILSSFSEQDYVLPALEAGADGYQLKEVQPEQLVASIIAIYEGNANFHPKVTPALLGRSAVKKENPFSM
LTKREQEVLQEIAKGRSNKEIAAELHITEQTVKTHVSNILAKLEVDDRTQAALYAVKHGEK

Sequences:

>Translated_221_residues
MKFNCRFEGGRRLKIKLLLVEDHHIVRRGLVFFLKTREEFEIVGEAENGEDALTFVRTERPDVVLMDLSMPKMDGIEATK
QIKQYDETIKILILSSFSEQDYVLPALEAGADGYQLKEVQPEQLVASIIAIYEGNANFHPKVTPALLGRSAVKKENPFSM
LTKREQEVLQEIAKGRSNKEIAAELHITEQTVKTHVSNILAKLEVDDRTQAALYAVKHGEK
>Mature_221_residues
MKFNCRFEGGRRLKIKLLLVEDHHIVRRGLVFFLKTREEFEIVGEAENGEDALTFVRTERPDVVLMDLSMPKMDGIEATK
QIKQYDETIKILILSSFSEQDYVLPALEAGADGYQLKEVQPEQLVASIIAIYEGNANFHPKVTPALLGRSAVKKENPFSM
LTKREQEVLQEIAKGRSNKEIAAELHITEQTVKTHVSNILAKLEVDDRTQAALYAVKHGEK

Specific function: Member of the two-component regulatory system yhcY/yhcZ [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=199, Percent_Identity=38.6934673366834, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1788222, Length=207, Percent_Identity=34.2995169082126, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787473, Length=201, Percent_Identity=34.8258706467662, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790102, Length=198, Percent_Identity=32.8282828282828, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1786747, Length=199, Percent_Identity=29.6482412060301, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788712, Length=191, Percent_Identity=27.2251308900524, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787277, Length=191, Percent_Identity=28.7958115183246, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788394, Length=217, Percent_Identity=25.3456221198157, Blast_Score=66, Evalue=1e-12,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=34.2342342342342, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1788724, Length=158, Percent_Identity=25.9493670886076, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI87082052, Length=110, Percent_Identity=33.6363636363636, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1786911, Length=128, Percent_Identity=33.59375, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 25034; Mature: 25034

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFNCRFEGGRRLKIKLLLVEDHHIVRRGLVFFLKTREEFEIVGEAENGEDALTFVRTER
CEEEEEECCCCEEEEEEEEECCCHHHHHHHEEEEECCCCEEEEECCCCCCCEEEEEECCC
PDVVLMDLSMPKMDGIEATKQIKQYDETIKILILSSFSEQDYVLPALEAGADGYQLKEVQ
CCEEEEECCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHCCCCCCEECCCC
PEQLVASIIAIYEGNANFHPKVTPALLGRSAVKKENPFSMLTKREQEVLQEIAKGRSNKE
HHHHHHHHHHHCCCCCCCCCCCCHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCE
IAAELHITEQTVKTHVSNILAKLEVDDRTQAALYAVKHGEK
EEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHEEEECCCCC
>Mature Secondary Structure
MKFNCRFEGGRRLKIKLLLVEDHHIVRRGLVFFLKTREEFEIVGEAENGEDALTFVRTER
CEEEEEECCCCEEEEEEEEECCCHHHHHHHEEEEECCCCEEEEECCCCCCCEEEEEECCC
PDVVLMDLSMPKMDGIEATKQIKQYDETIKILILSSFSEQDYVLPALEAGADGYQLKEVQ
CCEEEEECCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHCCCCCCEECCCC
PEQLVASIIAIYEGNANFHPKVTPALLGRSAVKKENPFSMLTKREQEVLQEIAKGRSNKE
HHHHHHHHHHHCCCCCCCCCCCCHHHHCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCE
IAAELHITEQTVKTHVSNILAKLEVDDRTQAALYAVKHGEK
EEEEEEEHHHHHHHHHHHHHHHCCCCCCHHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]