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The map label for this gene is citT [C]

Identifier: 118477642

GI number: 118477642

Start: 2123998

End: 2125428

Strand: Direct

Name: citT [C]

Synonym: BALH_1971

Alternate gene names: 118477642

Gene position: 2123998-2125428 (Clockwise)

Preceding gene: 118477641

Following gene: 118477643

Centisome position: 40.4

GC content: 32.08

Gene sequence:

>1431_bases
ATGATTGAAAAAAATGTAGTGGAATTACATGTGGATAATAATGATACTCCGAAAGTTAAGTCATCCTGGGTTCTGCCCGT
AGCACTTATATTAATTGTAGAAATAGTTCTTTTGCTTCCATCATCATTAACGATGGAAGCAAAATGGAGTTTGTTTGGAT
TTTGCTCTGCAATTATATTATGGACAACAACAACGATAAATTCGGCCTATATTGCACTCGGTTCTGTATTATTTCTAATT
ATTTCAGGAACAGCAAAGCAAGATCTTTTATTTGATTCGCTAGCTTCGGATGTCATTTGGCTTATGATCGGTTCGTTTAT
TTTAGGAAGAGCACTTCAAATTACCGGTCTAGCTGAAAAAATGACGTACTTTGTTGTGAATCGTGCTCGTAATATATCAG
GATTATGCTGGATTTTAACAATGATTATTCAAATACTTGCCTTTTTTATTCCATCTACATCGGGACGCGCAGCGGTTGTA
TTACCTGTTTTTCAAGCTATATGTAAAGAAATTGGAAGTAGAAGAATTGCGAAAGCATTAGCAATTTTAATGCCTACTGT
GATTTTAGTTTCAACAAGTTCTACAATTATTGGGGCAGGCTCACATTTAATCGCTCTAGATATGTTAAATGAATTTAATA
ATAAAAACATTACATTTGTAGAGTGGTTAATATGGGGATTACCATTTGGAATTATAATGAGCTTTATAAGTTGTCGCGTA
ATATTAGTACTATTTTTAGACAAAGAGGAAGTAAAAACGAAACTGCAACAGAAAAAAGTTAAGTTTGAATTATCACGAAA
TGAAAAGTATACAATAAGCATTTTAATAGCGATGGTAGCATTTTGGCTAACGGAATGGTTACACGGTTTGGAAATTGCAA
CTGTAACTATAATAGGAGTATTTTTATTAACTTTACCAAAACTCGGTGTGATGCAGTGGAAAGAAAGTTTAAAAGGTGTC
TCTTGGAATTTAATTTTATTTGTTGGAGCGGCAATTGCATTAGGGAAATCATTAATGGAAAGCGGTGCAGCGCAATGGAT
TATGCAGAATTTATTTTTAGTAACAGAATTAATTAATAAGCAATCCATTTTCATCGTGTTACTCGTAATTGTTATCCTTT
CAGTTACATCACATTTATATATTACATCTCACACTACGAGAGCAGTAATTTTTATTCCACCACTACTATACTTTGCAAGT
AGTCTGCAATTAAATGAAGTAGCTGTCTTATTTTTAGGTATTGTTGGAATGAATTATTGTTTAACCTTTCCGGTCAGTTC
TAAAGCACTACTATTATTTCAAGAAAGTGATAGAGAAACTTTTCAACCGCAAGATTTATTAAAATTAAGTAGTTATTTAA
GTGTTATTTATATATTTGTAATGGTCATATTTTACTATGCATATTGGCAATGGGTTGGATTATCTCTTTAA

Upstream 100 bases:

>100_bases
ATGCGGAGAAATGGCTTCGTGATTGTACAGAGAGTACGATGCGTACAGTTTTAGTTGGCTATCAAATCGCTTCTCGTTTA
AATAAAAGTGGGTACGTATC

Downstream 100 bases:

>100_bases
AAATCAGGAATATATTTCATTCCTGATTTTTTTCATTAAGGATAAAACATATTGGGTATTTTTTCTTTTGAAGGAAAGTA
TTACTTGTTATACTAAAATG

Product: transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MIEKNVVELHVDNNDTPKVKSSWVLPVALILIVEIVLLLPSSLTMEAKWSLFGFCSAIILWTTTTINSAYIALGSVLFLI
ISGTAKQDLLFDSLASDVIWLMIGSFILGRALQITGLAEKMTYFVVNRARNISGLCWILTMIIQILAFFIPSTSGRAAVV
LPVFQAICKEIGSRRIAKALAILMPTVILVSTSSTIIGAGSHLIALDMLNEFNNKNITFVEWLIWGLPFGIIMSFISCRV
ILVLFLDKEEVKTKLQQKKVKFELSRNEKYTISILIAMVAFWLTEWLHGLEIATVTIIGVFLLTLPKLGVMQWKESLKGV
SWNLILFVGAAIALGKSLMESGAAQWIMQNLFLVTELINKQSIFIVLLVIVILSVTSHLYITSHTTRAVIFIPPLLYFAS
SLQLNEVAVLFLGIVGMNYCLTFPVSSKALLLFQESDRETFQPQDLLKLSSYLSVIYIFVMVIFYYAYWQWVGLSL

Sequences:

>Translated_476_residues
MIEKNVVELHVDNNDTPKVKSSWVLPVALILIVEIVLLLPSSLTMEAKWSLFGFCSAIILWTTTTINSAYIALGSVLFLI
ISGTAKQDLLFDSLASDVIWLMIGSFILGRALQITGLAEKMTYFVVNRARNISGLCWILTMIIQILAFFIPSTSGRAAVV
LPVFQAICKEIGSRRIAKALAILMPTVILVSTSSTIIGAGSHLIALDMLNEFNNKNITFVEWLIWGLPFGIIMSFISCRV
ILVLFLDKEEVKTKLQQKKVKFELSRNEKYTISILIAMVAFWLTEWLHGLEIATVTIIGVFLLTLPKLGVMQWKESLKGV
SWNLILFVGAAIALGKSLMESGAAQWIMQNLFLVTELINKQSIFIVLLVIVILSVTSHLYITSHTTRAVIFIPPLLYFAS
SLQLNEVAVLFLGIVGMNYCLTFPVSSKALLLFQESDRETFQPQDLLKLSSYLSVIYIFVMVIFYYAYWQWVGLSL
>Mature_476_residues
MIEKNVVELHVDNNDTPKVKSSWVLPVALILIVEIVLLLPSSLTMEAKWSLFGFCSAIILWTTTTINSAYIALGSVLFLI
ISGTAKQDLLFDSLASDVIWLMIGSFILGRALQITGLAEKMTYFVVNRARNISGLCWILTMIIQILAFFIPSTSGRAAVV
LPVFQAICKEIGSRRIAKALAILMPTVILVSTSSTIIGAGSHLIALDMLNEFNNKNITFVEWLIWGLPFGIIMSFISCRV
ILVLFLDKEEVKTKLQQKKVKFELSRNEKYTISILIAMVAFWLTEWLHGLEIATVTIIGVFLLTLPKLGVMQWKESLKGV
SWNLILFVGAAIALGKSLMESGAAQWIMQNLFLVTELINKQSIFIVLLVIVILSVTSHLYITSHTTRAVIFIPPLLYFAS
SLQLNEVAVLFLGIVGMNYCLTFPVSSKALLLFQESDRETFQPQDLLKLSSYLSVIYIFVMVIFYYAYWQWVGLSL

Specific function: Responsible For The Uptake Of Citrate In Exchange To The Efflux Of Succinate. Has A Relatively Broad Specificity For C(4)- Dicarboxylates And Tricarboxylates. [C]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. SODIT1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI301069349, Length=304, Percent_Identity=24.6710526315789, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1786829, Length=388, Percent_Identity=23.4536082474227, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786986, Length=350, Percent_Identity=24.8571428571429, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 53257; Mature: 53257

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEKNVVELHVDNNDTPKVKSSWVLPVALILIVEIVLLLPSSLTMEAKWSLFGFCSAIIL
CCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
WTTTTINSAYIALGSVLFLIISGTAKQDLLFDSLASDVIWLMIGSFILGRALQITGLAEK
HHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
MTYFVVNRARNISGLCWILTMIIQILAFFIPSTSGRAAVVLPVFQAICKEIGSRRIAKAL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
AILMPTVILVSTSSTIIGAGSHLIALDMLNEFNNKNITFVEWLIWGLPFGIIMSFISCRV
HHHHHHHHEEECCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHH
ILVLFLDKEEVKTKLQQKKVKFELSRNEKYTISILIAMVAFWLTEWLHGLEIATVTIIGV
HHHHHCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLTLPKLGVMQWKESLKGVSWNLILFVGAAIALGKSLMESGAAQWIMQNLFLVTELINK
HHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QSIFIVLLVIVILSVTSHLYITSHTTRAVIFIPPLLYFASSLQLNEVAVLFLGIVGMNYC
CHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHE
LTFPVSSKALLLFQESDRETFQPQDLLKLSSYLSVIYIFVMVIFYYAYWQWVGLSL
EECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIEKNVVELHVDNNDTPKVKSSWVLPVALILIVEIVLLLPSSLTMEAKWSLFGFCSAIIL
CCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
WTTTTINSAYIALGSVLFLIISGTAKQDLLFDSLASDVIWLMIGSFILGRALQITGLAEK
HHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
MTYFVVNRARNISGLCWILTMIIQILAFFIPSTSGRAAVVLPVFQAICKEIGSRRIAKAL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
AILMPTVILVSTSSTIIGAGSHLIALDMLNEFNNKNITFVEWLIWGLPFGIIMSFISCRV
HHHHHHHHEEECCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHH
ILVLFLDKEEVKTKLQQKKVKFELSRNEKYTISILIAMVAFWLTEWLHGLEIATVTIIGV
HHHHHCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLLTLPKLGVMQWKESLKGVSWNLILFVGAAIALGKSLMESGAAQWIMQNLFLVTELINK
HHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QSIFIVLLVIVILSVTSHLYITSHTTRAVIFIPPLLYFASSLQLNEVAVLFLGIVGMNYC
CHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECHHHHHHCCCCHHHHHHHHHHHHHHHHE
LTFPVSSKALLLFQESDRETFQPQDLLKLSSYLSVIYIFVMVIFYYAYWQWVGLSL
EECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8405966 [H]