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The map label for this gene is bsaA [H]

Identifier: 118477556

GI number: 118477556

Start: 2030014

End: 2030523

Strand: Direct

Name: bsaA [H]

Synonym: BALH_1881

Alternate gene names: 118477556

Gene position: 2030014-2030523 (Clockwise)

Preceding gene: 118477554

Following gene: 118477562

Centisome position: 38.61

GC content: 36.47

Gene sequence:

>510_bases
ATGATAGTGAAGAGAGGGGCAAAGACAATGACAGTTTATGATTTTTCAGCTAAAACAATAACAGGTGAAGAAAAATCGTT
AAAAGATTACGAGGGAAAAGTACTTCTTATTGTAAATGTAGCTAGTAAATGCGGGTTTACACCGCAATATAAAGGATTAC
AAGAAGTATATGATAAATATAAAGAACAAGGGCTAGAAATACTCGGTTTCCCATGTAACCAATTCGGAGGACAAGAACCA
GGTACAGAAGCAGATATTACAAGCTTTTGTGAATTAAACTACGGTGTAAACTTCCCAATGTTTGCAAAAATTGATGTAAA
AGGTGATAAGGCTCATCCTCTGTATACATACATGACAGAACAAGCACCAGGTTTACTCGGTATGAAAGCAGTAAAATGGA
ACTTTACAAAATTTCTAATTGGAAAAGACGGAAAAGTAGTAGGGCGTTTTGCACCGCAAACGAAGCCGGTGGATTTAGAG
GTTGAGATTGAGAAGGTACTTGGTGAATAA

Upstream 100 bases:

>100_bases
GTGTCGAATTTTCGAACGGAAATAAAGCGTTTACAATCGTGGGGAGAAAATACGTAATAAGAGCTGTAAATTCACGAATG
TAGTATAGTATAAACATAGA

Downstream 100 bases:

>100_bases
CTAGGAGTTTCACTTTATTAAAAAATGCCTCAAAGAACTATTTTGTTCTTTGAGGCATTTTATTTACATTCACATTGTCA
ATATTAAATCGCTGAATGGA

Product: glutathione peroxidase

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MIVKRGAKTMTVYDFSAKTITGEEKSLKDYEGKVLLIVNVASKCGFTPQYKGLQEVYDKYKEQGLEILGFPCNQFGGQEP
GTEADITSFCELNYGVNFPMFAKIDVKGDKAHPLYTYMTEQAPGLLGMKAVKWNFTKFLIGKDGKVVGRFAPQTKPVDLE
VEIEKVLGE

Sequences:

>Translated_169_residues
MIVKRGAKTMTVYDFSAKTITGEEKSLKDYEGKVLLIVNVASKCGFTPQYKGLQEVYDKYKEQGLEILGFPCNQFGGQEP
GTEADITSFCELNYGVNFPMFAKIDVKGDKAHPLYTYMTEQAPGLLGMKAVKWNFTKFLIGKDGKVVGRFAPQTKPVDLE
VEIEKVLGE
>Mature_169_residues
MIVKRGAKTMTVYDFSAKTITGEEKSLKDYEGKVLLIVNVASKCGFTPQYKGLQEVYDKYKEQGLEILGFPCNQFGGQEP
GTEADITSFCELNYGVNFPMFAKIDVKGDKAHPLYTYMTEQAPGLLGMKAVKWNFTKFLIGKDGKVVGRFAPQTKPVDLE
VEIEKVLGE

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=162, Percent_Identity=47.5308641975309, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI90903240, Length=162, Percent_Identity=47.5308641975309, Blast_Score=138, Evalue=3e-33,
Organism=Homo sapiens, GI15618997, Length=141, Percent_Identity=48.2269503546099, Blast_Score=133, Evalue=7e-32,
Organism=Homo sapiens, GI90903238, Length=137, Percent_Identity=48.9051094890511, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI192455698, Length=153, Percent_Identity=37.2549019607843, Blast_Score=114, Evalue=4e-26,
Organism=Homo sapiens, GI6006001, Length=179, Percent_Identity=37.4301675977654, Blast_Score=106, Evalue=8e-24,
Organism=Homo sapiens, GI41406084, Length=184, Percent_Identity=35.3260869565217, Blast_Score=103, Evalue=6e-23,
Organism=Homo sapiens, GI4557629, Length=173, Percent_Identity=34.6820809248555, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI33186887, Length=181, Percent_Identity=34.8066298342541, Blast_Score=96, Evalue=1e-20,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=29.2817679558011, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1788003, Length=160, Percent_Identity=43.75, Blast_Score=148, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17506887, Length=160, Percent_Identity=51.25, Blast_Score=173, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17535473, Length=158, Percent_Identity=48.7341772151899, Blast_Score=162, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI193210707, Length=172, Percent_Identity=44.7674418604651, Blast_Score=144, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71993584, Length=159, Percent_Identity=41.5094339622642, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17550320, Length=169, Percent_Identity=34.9112426035503, Blast_Score=109, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI193209493, Length=163, Percent_Identity=33.7423312883436, Blast_Score=109, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=42.1052631578947, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=46.0526315789474, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI193210709, Length=80, Percent_Identity=48.75, Blast_Score=78, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17507603, Length=106, Percent_Identity=35.8490566037736, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=161, Percent_Identity=55.9006211180124, Blast_Score=193, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6322228, Length=139, Percent_Identity=56.1151079136691, Blast_Score=174, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6322826, Length=157, Percent_Identity=45.2229299363057, Blast_Score=149, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24656772, Length=161, Percent_Identity=47.8260869565217, Blast_Score=145, Evalue=9e-36,
Organism=Drosophila melanogaster, GI24656767, Length=164, Percent_Identity=47.5609756097561, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24656777, Length=161, Percent_Identity=47.8260869565217, Blast_Score=144, Evalue=3e-35,
Organism=Drosophila melanogaster, GI85726443, Length=162, Percent_Identity=40.7407407407407, Blast_Score=126, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 18824; Mature: 18824

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVKRGAKTMTVYDFSAKTITGEEKSLKDYEGKVLLIVNVASKCGFTPQYKGLQEVYDKY
CEECCCCCEEEEEECCCEEECCCCCCCCCCCCCEEEEEEEHHHCCCCCCCCCHHHHHHHH
KEQGLEILGFPCNQFGGQEPGTEADITSFCELNYGVNFPMFAKIDVKGDKAHPLYTYMTE
HHCCCEEEECCCHHCCCCCCCCCCCHHEEEEECCCCCCCEEEEEEECCCCCCCEEEEECC
QAPGLLGMKAVKWNFTKFLIGKDGKVVGRFAPQTKPVDLEVEIEKVLGE
CCCCCCCEEEEEEEEEEEEECCCCCEEEEECCCCCCCEEEEEHHHHHCC
>Mature Secondary Structure
MIVKRGAKTMTVYDFSAKTITGEEKSLKDYEGKVLLIVNVASKCGFTPQYKGLQEVYDKY
CEECCCCCEEEEEECCCEEECCCCCCCCCCCCCEEEEEEEHHHCCCCCCCCCHHHHHHHH
KEQGLEILGFPCNQFGGQEPGTEADITSFCELNYGVNFPMFAKIDVKGDKAHPLYTYMTE
HHCCCEEEECCCHHCCCCCCCCCCCHHEEEEECCCCCCCEEEEEEECCCCCCCEEEEECC
QAPGLLGMKAVKWNFTKFLIGKDGKVVGRFAPQTKPVDLEVEIEKVLGE
CCCCCCCEEEEEEEEEEEEECCCCCEEEEECCCCCCCEEEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]