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The map label for this gene is adcA [H]

Identifier: 118477474

GI number: 118477474

Start: 1952724

End: 1953737

Strand: Reverse

Name: adcA [H]

Synonym: BALH_1796

Alternate gene names: 118477474

Gene position: 1953737-1952724 (Counterclockwise)

Preceding gene: 118477476

Following gene: 118477473

Centisome position: 37.16

GC content: 32.84

Gene sequence:

>1014_bases
ATGATATGTTTCTTCTATAATTGGGGAAAATATATCCGTAAAAAAAGAAAAGAGGAGAACTTCATGCCTAAAAGATTGAC
TATATTTTCATTCTTACTTATTTTCACTTTAATTTTTACTGGCTGCTCAAATACAAAAGAAGGTAATGCCAAGAAAGACG
GAAAGCTAACTGTTTATACAACTATTTTTCCTCTTGCAGATTTTGCAAAAAAAATTGGTGGCGACTATGTAACGGTTGAA
GCGATTTACCCACCTGGTGCAGATTCTCATACATTTGAACCAAGTCAAAAACAAACAGTAAAAGTTGCAAAAGCCGATTT
ATTCGTTTATAACGGAGCTGAATTAGAGCCATTTGCTGAAAAAATGGAAAAATCATTACAAAAAGAAAATGTTAAAATTG
TAAATGCATCAAAAGGTATTGAACTGCGTACTTCTACTGAAGAAGAGCATCATGATCACGGAGACGGCCATAAAGAAGAG
GAACATCATCACGATAAAGATCCACACATTTGGTTAGACCCTACTCTAGCAATGAAACAAGCAGAAAAAATTAAAAATGC
ACTTGTAGCATTACAACCTGAGCATAAACAAGAGTTCGAAAAAAACTTTGCAGCACTTCAAACAAAATTTACTGATTTAG
ATGATCAATTTAAAGCAGTTGTTTCGAATGCAAAAACGAAAGATATTTTAGTTTCTCATGCAGCTTATGGATACTGGGAA
CAACGCTATGGCCTAAAACAAATTGCTATCGCTGGTATTTCAGCTTCTGATGAACCTTCTCAAAAACAGCTTGCTGATAT
TACAAAAACAGTAAAAGAACATAATCTAAAATATATTTTATTTGAAACATTCTCTACTCCAAAAGTAGCATCCGTTATTC
AAAAAGAAACGGGTACAAAAGTTTTACGTTTAAATCATCTTGCTACTATTTCTGAAGATGATGCGAAGAGCAATAAAGAT
TACTTCACTTTAATGGAAGAAAACGTAAACACATTGAAAGAAGCTACTAACTAA

Upstream 100 bases:

>100_bases
CAAAATCAAATCGGAATGATTATTATTTATTGCAACTTTATAAAAGATGTATTATACTAAGTTCGCAAACTAAAACGTAA
TTATTCCGTTTTGTATTAAA

Downstream 100 bases:

>100_bases
CCAACTTTTGATAAGAAGAGGCTGTCTCAAAAGGTCTTTAAATAAGACCTTTTGGAGACAGTTTTTTATTTTAACTTTAA
TATGGATGAGAAAATCTTTA

Product: high-affinity zinc uptake system periplasmic-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MICFFYNWGKYIRKKRKEENFMPKRLTIFSFLLIFTLIFTGCSNTKEGNAKKDGKLTVYTTIFPLADFAKKIGGDYVTVE
AIYPPGADSHTFEPSQKQTVKVAKADLFVYNGAELEPFAEKMEKSLQKENVKIVNASKGIELRTSTEEEHHDHGDGHKEE
EHHHDKDPHIWLDPTLAMKQAEKIKNALVALQPEHKQEFEKNFAALQTKFTDLDDQFKAVVSNAKTKDILVSHAAYGYWE
QRYGLKQIAIAGISASDEPSQKQLADITKTVKEHNLKYILFETFSTPKVASVIQKETGTKVLRLNHLATISEDDAKSNKD
YFTLMEENVNTLKEATN

Sequences:

>Translated_337_residues
MICFFYNWGKYIRKKRKEENFMPKRLTIFSFLLIFTLIFTGCSNTKEGNAKKDGKLTVYTTIFPLADFAKKIGGDYVTVE
AIYPPGADSHTFEPSQKQTVKVAKADLFVYNGAELEPFAEKMEKSLQKENVKIVNASKGIELRTSTEEEHHDHGDGHKEE
EHHHDKDPHIWLDPTLAMKQAEKIKNALVALQPEHKQEFEKNFAALQTKFTDLDDQFKAVVSNAKTKDILVSHAAYGYWE
QRYGLKQIAIAGISASDEPSQKQLADITKTVKEHNLKYILFETFSTPKVASVIQKETGTKVLRLNHLATISEDDAKSNKD
YFTLMEENVNTLKEATN
>Mature_337_residues
MICFFYNWGKYIRKKRKEENFMPKRLTIFSFLLIFTLIFTGCSNTKEGNAKKDGKLTVYTTIFPLADFAKKIGGDYVTVE
AIYPPGADSHTFEPSQKQTVKVAKADLFVYNGAELEPFAEKMEKSLQKENVKIVNASKGIELRTSTEEEHHDHGDGHKEE
EHHHDKDPHIWLDPTLAMKQAEKIKNALVALQPEHKQEFEKNFAALQTKFTDLDDQFKAVVSNAKTKDILVSHAAYGYWE
QRYGLKQIAIAGISASDEPSQKQLADITKTVKEHNLKYILFETFSTPKVASVIQKETGTKVLRLNHLATISEDDAKSNKD
YFTLMEENVNTLKEATN

Specific function: Part of the ATP-driven transport system AdcABC for zinc [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=274, Percent_Identity=24.4525547445255, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR006128
- InterPro:   IPR015304 [H]

Pfam domain/function: PF01297 SBP_bac_9; PF09223 YodA [H]

EC number: NA

Molecular weight: Translated: 38384; Mature: 38384

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICFFYNWGKYIRKKRKEENFMPKRLTIFSFLLIFTLIFTGCSNTKEGNAKKDGKLTVYT
CEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
TIFPLADFAKKIGGDYVTVEAIYPPGADSHTFEPSQKQTVKVAKADLFVYNGAELEPFAE
EHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHEEEEEEEEEECCCCCCHHHH
KMEKSLQKENVKIVNASKGIELRTSTEEEHHDHGDGHKEEEHHHDKDPHIWLDPTLAMKQ
HHHHHHHHCCEEEEECCCCEEEEECCCHHHCCCCCCCCCHHHCCCCCCEEEECCHHHHHH
AEKIKNALVALQPEHKQEFEKNFAALQTKFTDLDDQFKAVVSNAKTKDILVSHAAYGYWE
HHHHHHHHEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
QRYGLKQIAIAGISASDEPSQKQLADITKTVKEHNLKYILFETFSTPKVASVIQKETGTK
HHCCHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCE
VLRLNHLATISEDDAKSNKDYFTLMEENVNTLKEATN
EEEEEHHEECCCCCCCCCCCEEEEHHHHHHHHHHCCC
>Mature Secondary Structure
MICFFYNWGKYIRKKRKEENFMPKRLTIFSFLLIFTLIFTGCSNTKEGNAKKDGKLTVYT
CEEEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
TIFPLADFAKKIGGDYVTVEAIYPPGADSHTFEPSQKQTVKVAKADLFVYNGAELEPFAE
EHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCHHHHHEEEEEEEEEECCCCCCHHHH
KMEKSLQKENVKIVNASKGIELRTSTEEEHHDHGDGHKEEEHHHDKDPHIWLDPTLAMKQ
HHHHHHHHCCEEEEECCCCEEEEECCCHHHCCCCCCCCCHHHCCCCCCEEEECCHHHHHH
AEKIKNALVALQPEHKQEFEKNFAALQTKFTDLDDQFKAVVSNAKTKDILVSHAAYGYWE
HHHHHHHHEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
QRYGLKQIAIAGISASDEPSQKQLADITKTVKEHNLKYILFETFSTPKVASVIQKETGTK
HHCCHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCE
VLRLNHLATISEDDAKSNKDYFTLMEENVNTLKEATN
EEEEEHHEECCCCCCCCCCCEEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]