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The map label for this gene is nadE

Identifier: 118477447

GI number: 118477447

Start: 1926440

End: 1927258

Strand: Reverse

Name: nadE

Synonym: BALH_1767

Alternate gene names: 118477447

Gene position: 1927258-1926440 (Counterclockwise)

Preceding gene: 118477451

Following gene: 118477443

Centisome position: 36.66

GC content: 39.07

Gene sequence:

>819_bases
ATGACATTGCAAGAACAGATTATGAAAGCATTACACGTTCAACCTGTAATTGACCCGAAAGCAGAAATCCGTAAACGTGT
TGATTTCTTAAAAGATTATGTAAAAAAAACAGGTGCGAAAGGATTTGTACTTGGAATTAGTGGCGGACAAGACTCTACAT
TAGCTGGACGTTTAGCTCAGCTTGCAGTGGAGGAAATTCGTAATGAAGGTGGTAACGCAACGTTTATCGCCGTGCGCCTT
CCTTATAAAGTGCAAAAAGACGAAGATGATGCGCAATTAGCATTACAATTTATTCAAGCTGATCAATCTGTTGCATTTGA
TATCGCTTCAACTGTTGATGCTTTCTCAAATCAATACGAAAACTTATTAGATGAATCGTTAACAGATTTCAATAAAGGTA
ACGTGAAAGCACGTATCCGCATGGTTACACAATATGCAATCGGTGGACAAAAAGGGCTCCTTGTTATCGGAACAGATCAC
GCTGCAGAAGCTGTAACAGGATTCTTTACAAAATTCGGAGATGGTGGTGCAGACCTATTACCATTAACGGGATTAACGAA
ACGCCAAGGACGCGCTCTATTACAAGAATTAGGTGCGGACGAGCGACTTTACTTAAAAATGCCAACAGCTGATTTATTAG
ATGAAAAACCAGGTCAAGCTGATGAAACAGAGTTAGGTATTACGTATGATCAACTTGATGACTATTTAGAAGGTAAAACA
GTTCCAGCTGACGTTGCAGAAAAGATTGAAAAACGTTACACAGTGAGTGAGCATAAAAGACAAGTACCAGCATCAATGTT
TGATGATTGGTGGAAATAA

Upstream 100 bases:

>100_bases
TGTATATTCGTTAATTTTGCGAAATAATAAAGGATAGAAGTATGTACCAATATACATATAAACTTATTTATCGCTTTAAT
ATGAATAGGAGGAAAACATA

Downstream 100 bases:

>100_bases
ATAAAACATAAAAAAGAAGCTAATCTCATTTAGCTTCTTTTTTATGTTAACGATATACCCCTACCCTTTTCTCCAATAAA
TCTTGCAGGCAATCTTCATG

Product: NAD synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTLQEQIMKALHVQPVIDPKAEIRKRVDFLKDYVKKTGAKGFVLGISGGQDSTLAGRLAQLAVEEIRNEGGNATFIAVRL
PYKVQKDEDDAQLALQFIQADQSVAFDIASTVDAFSNQYENLLDESLTDFNKGNVKARIRMVTQYAIGGQKGLLVIGTDH
AAEAVTGFFTKFGDGGADLLPLTGLTKRQGRALLQELGADERLYLKMPTADLLDEKPGQADETELGITYDQLDDYLEGKT
VPADVAEKIEKRYTVSEHKRQVPASMFDDWWK

Sequences:

>Translated_272_residues
MTLQEQIMKALHVQPVIDPKAEIRKRVDFLKDYVKKTGAKGFVLGISGGQDSTLAGRLAQLAVEEIRNEGGNATFIAVRL
PYKVQKDEDDAQLALQFIQADQSVAFDIASTVDAFSNQYENLLDESLTDFNKGNVKARIRMVTQYAIGGQKGLLVIGTDH
AAEAVTGFFTKFGDGGADLLPLTGLTKRQGRALLQELGADERLYLKMPTADLLDEKPGQADETELGITYDQLDDYLEGKT
VPADVAEKIEKRYTVSEHKRQVPASMFDDWWK
>Mature_271_residues
TLQEQIMKALHVQPVIDPKAEIRKRVDFLKDYVKKTGAKGFVLGISGGQDSTLAGRLAQLAVEEIRNEGGNATFIAVRLP
YKVQKDEDDAQLALQFIQADQSVAFDIASTVDAFSNQYENLLDESLTDFNKGNVKARIRMVTQYAIGGQKGLLVIGTDHA
AEAVTGFFTKFGDGGADLLPLTGLTKRQGRALLQELGADERLYLKMPTADLLDEKPGQADETELGITYDQLDDYLEGKTV
PADVAEKIEKRYTVSEHKRQVPASMFDDWWK

Specific function: This NAD Synthase Uses Nh(3) In Preference To Glutamine. [C]

COG id: COG0171

COG function: function code H; NAD synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD synthetase family

Homologues:

Organism=Escherichia coli, GI1788036, Length=275, Percent_Identity=55.6363636363636, Blast_Score=291, Evalue=5e-80,
Organism=Caenorhabditis elegans, GI17538756, Length=261, Percent_Identity=28.3524904214559, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NADE_BACAA (C3P7H9)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002866392.1
- ProteinModelPortal:   C3P7H9
- SMR:   C3P7H9
- EnsemblBacteria:   EBBACT00000130066
- GeneID:   7850317
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_2067
- GeneTree:   EBGT00050000001308
- ProtClustDB:   PRK00768
- HAMAP:   MF_00193
- InterPro:   IPR022310
- InterPro:   IPR003694
- InterPro:   IPR022926
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- TIGRFAMs:   TIGR00552

Pfam domain/function: PF02540 NAD_synthase

EC number: =6.3.1.5

Molecular weight: Translated: 30101; Mature: 29970

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: ACT_SITE 47-47

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQEQIMKALHVQPVIDPKAEIRKRVDFLKDYVKKTGAKGFVLGISGGQDSTLAGRLAQ
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHH
LAVEEIRNEGGNATFIAVRLPYKVQKDEDDAQLALQFIQADQSVAFDIASTVDAFSNQYE
HHHHHHHCCCCCEEEEEEECCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
NLLDESLTDFNKGNVKARIRMVTQYAIGGQKGLLVIGTDHAAEAVTGFFTKFGDGGADLL
HHHHHHHHCCCCCCCEEHHEEHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEE
PLTGLTKRQGRALLQELGADERLYLKMPTADLLDEKPGQADETELGITYDQLDDYLEGKT
ECCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCC
VPADVAEKIEKRYTVSEHKRQVPASMFDDWWK
CCHHHHHHHHHHCCHHHHHHCCCHHHHHHHCC
>Mature Secondary Structure 
TLQEQIMKALHVQPVIDPKAEIRKRVDFLKDYVKKTGAKGFVLGISGGQDSTLAGRLAQ
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHH
LAVEEIRNEGGNATFIAVRLPYKVQKDEDDAQLALQFIQADQSVAFDIASTVDAFSNQYE
HHHHHHHCCCCCEEEEEEECCEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
NLLDESLTDFNKGNVKARIRMVTQYAIGGQKGLLVIGTDHAAEAVTGFFTKFGDGGADLL
HHHHHHHHCCCCCCCEEHHEEHHHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCEE
PLTGLTKRQGRALLQELGADERLYLKMPTADLLDEKPGQADETELGITYDQLDDYLEGKT
ECCCCCHHHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCC
VPADVAEKIEKRYTVSEHKRQVPASMFDDWWK
CCHHHHHHHHHHCCHHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA