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The map label for this gene is yfnA [H]

Identifier: 118476477

GI number: 118476477

Start: 852687

End: 854090

Strand: Reverse

Name: yfnA [H]

Synonym: BALH_0742

Alternate gene names: 118476477

Gene position: 854090-852687 (Counterclockwise)

Preceding gene: 118476487

Following gene: 118476472

Centisome position: 16.25

GC content: 40.53

Gene sequence:

>1404_bases
GTGAAGTCATTATTACGAAAAAAAGCGCTTAGTACTGAATCACCACGGCAACTACAAAGAACATTAACCGCACTTGATTT
AACGTTTTTAGGAATTGGCGCCGTAATTGGGACAGGGATATTTGTATTAACAGGTATTGTTGCAGCGAAACATTCTGGTC
CTGGTATTATGCTATCATTTCTTATTGCTGCATTTACTTGTGCTTGTGTAGCCTTTTGTTATGCCGAATTTGCTTCTTCT
ATTCCTGTCTCAGGCAGTGTGTATACTTACGCATACATGACAGTTGGCGAAGTCGTCGCCTTCATCGTTGGATGGTGTTT
AATGCTCGAATATTTACTTGCAGTCGCAGCAGTAGCTGTCGGTTGGTCTGGTTATTTACAATCTTTACTACAAGGATTTA
ACATCCATCTGCCCGCCATAATCGCCTCGGCCCCTGGCGTAGGAAAAGGTGGTCTCATCGATTTACCAGCTGTTTGTATT
TTACTCATCATTACCGGTCTTTTAAGTTTTGGTATACGTGAAAGCGCACGCATTAATAATATTATGGTTCTTATTAAATT
GGCTGTTATTATCGCCTTTATCGTAGCAGGCGCAAAATATGTAAAACCTGAAAATTGGACACCGTTCATTCCATTCGGAT
ACGACGGTATTATTACTGGAGCTGCCACTGTATTCTTCGCCTTCTTGGGCTTTGATGCAATCGCAACTGCTGCGGAAGAA
ACGAAAAAACCACAGCGCGATTTACCAATCGGCATTATCGGTTCCCTTCTTATTTGTACTGTTTTATATATGATCGTATC
TTTCGTTTTAACAGGTATGGTTCCTTATACACAATTAGATGTTTCTGATCCAGTTGCGTTTGCCTTACATTTCGTTGGTG
AAGATACCATTGCAGGACTACTCGCTGTTGGAGCGATGACTGGAATGACAACCGTTCTCTTAGTCGTTATGTATGGACAA
GTTCGCGTTTCGTATGCGATGAGCCGTGACGGTTTACTTCCAAAAGCGTTAGCACGTGTGAATAAAAGAGTGAAAATCCC
TTTATTAAACACGTGGATTACTGGTGTTGTTGCCGCTTTATTAGCAGGACTTTTAGACCTGCACGTATTAGCGAATTTAG
TAAACATCGGGACATTAACAGCCTTTACATTCGTTTGCTGCGCAGTACTTATTTTACGAAAAACACACCCTGACTTAAAA
CGCGGATTCCGTACACCTTTCGTACCTGTACTACCAGTTGTCGCGATTCTTTGCTGCTTATATTTAATGATCAATTTGTC
TAAAACAACATGGATTAGCTTTGCCGTTTGGCTTATAGTCGGATTATGCTTCTATTTCTTCTATTCTAGAAAGCATAGCC
ATTTAGCTACCGAAAAAACGAATGATGAACAGAAAAAAGCATAA

Upstream 100 bases:

>100_bases
ATATACCATAACTGTACCTCCATTTACTTACATACTCTTTTCTAGTGGGCTCCTACTACATTCGCGGTTATGGAAATGAA
AAACGGGGGGAGAGTCCAAA

Downstream 100 bases:

>100_bases
CAAAATAGCTCGCCGTTTTAGCGGCGAGCTATCTTTCTGTACTATTATATTTTTTCGTTAACGATTGTAAAATGAAAAAT
ATGCCGATGCAAGCTGTAAA

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKSLLRKKALSTESPRQLQRTLTALDLTFLGIGAVIGTGIFVLTGIVAAKHSGPGIMLSFLIAAFTCACVAFCYAEFASS
IPVSGSVYTYAYMTVGEVVAFIVGWCLMLEYLLAVAAVAVGWSGYLQSLLQGFNIHLPAIIASAPGVGKGGLIDLPAVCI
LLIITGLLSFGIRESARINNIMVLIKLAVIIAFIVAGAKYVKPENWTPFIPFGYDGIITGAATVFFAFLGFDAIATAAEE
TKKPQRDLPIGIIGSLLICTVLYMIVSFVLTGMVPYTQLDVSDPVAFALHFVGEDTIAGLLAVGAMTGMTTVLLVVMYGQ
VRVSYAMSRDGLLPKALARVNKRVKIPLLNTWITGVVAALLAGLLDLHVLANLVNIGTLTAFTFVCCAVLILRKTHPDLK
RGFRTPFVPVLPVVAILCCLYLMINLSKTTWISFAVWLIVGLCFYFFYSRKHSHLATEKTNDEQKKA

Sequences:

>Translated_467_residues
MKSLLRKKALSTESPRQLQRTLTALDLTFLGIGAVIGTGIFVLTGIVAAKHSGPGIMLSFLIAAFTCACVAFCYAEFASS
IPVSGSVYTYAYMTVGEVVAFIVGWCLMLEYLLAVAAVAVGWSGYLQSLLQGFNIHLPAIIASAPGVGKGGLIDLPAVCI
LLIITGLLSFGIRESARINNIMVLIKLAVIIAFIVAGAKYVKPENWTPFIPFGYDGIITGAATVFFAFLGFDAIATAAEE
TKKPQRDLPIGIIGSLLICTVLYMIVSFVLTGMVPYTQLDVSDPVAFALHFVGEDTIAGLLAVGAMTGMTTVLLVVMYGQ
VRVSYAMSRDGLLPKALARVNKRVKIPLLNTWITGVVAALLAGLLDLHVLANLVNIGTLTAFTFVCCAVLILRKTHPDLK
RGFRTPFVPVLPVVAILCCLYLMINLSKTTWISFAVWLIVGLCFYFFYSRKHSHLATEKTNDEQKKA
>Mature_467_residues
MKSLLRKKALSTESPRQLQRTLTALDLTFLGIGAVIGTGIFVLTGIVAAKHSGPGIMLSFLIAAFTCACVAFCYAEFASS
IPVSGSVYTYAYMTVGEVVAFIVGWCLMLEYLLAVAAVAVGWSGYLQSLLQGFNIHLPAIIASAPGVGKGGLIDLPAVCI
LLIITGLLSFGIRESARINNIMVLIKLAVIIAFIVAGAKYVKPENWTPFIPFGYDGIITGAATVFFAFLGFDAIATAAEE
TKKPQRDLPIGIIGSLLICTVLYMIVSFVLTGMVPYTQLDVSDPVAFALHFVGEDTIAGLLAVGAMTGMTTVLLVVMYGQ
VRVSYAMSRDGLLPKALARVNKRVKIPLLNTWITGVVAALLAGLLDLHVLANLVNIGTLTAFTFVCCAVLILRKTHPDLK
RGFRTPFVPVLPVVAILCCLYLMINLSKTTWISFAVWLIVGLCFYFFYSRKHSHLATEKTNDEQKKA

Specific function: Transporter For The Intake Of S-Methylmethionine. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258614005, Length=425, Percent_Identity=39.7647058823529, Blast_Score=284, Evalue=2e-76,
Organism=Homo sapiens, GI258614003, Length=425, Percent_Identity=39.7647058823529, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI258645169, Length=425, Percent_Identity=39.7647058823529, Blast_Score=279, Evalue=5e-75,
Organism=Homo sapiens, GI4507047, Length=437, Percent_Identity=38.9016018306636, Blast_Score=275, Evalue=6e-74,
Organism=Homo sapiens, GI114326544, Length=434, Percent_Identity=37.7880184331797, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI114326550, Length=434, Percent_Identity=37.7880184331797, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI181337167, Length=409, Percent_Identity=38.6308068459658, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI110347453, Length=401, Percent_Identity=38.4039900249377, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI186910308, Length=470, Percent_Identity=25.1063829787234, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI186910306, Length=470, Percent_Identity=25.1063829787234, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI186910304, Length=470, Percent_Identity=25.1063829787234, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI71979932, Length=461, Percent_Identity=25.5965292841649, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI187423910, Length=475, Percent_Identity=22.9473684210526, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI7657591, Length=475, Percent_Identity=22.9473684210526, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI115648063, Length=428, Percent_Identity=24.0654205607477, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI115648022, Length=428, Percent_Identity=24.0654205607477, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI7657683, Length=362, Percent_Identity=25.414364640884, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI33286428, Length=413, Percent_Identity=24.9394673123487, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87081708, Length=491, Percent_Identity=23.6252545824847, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI87082023, Length=454, Percent_Identity=26.431718061674, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87081869, Length=459, Percent_Identity=27.2331154684096, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1788480, Length=451, Percent_Identity=27.0509977827051, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1786302, Length=364, Percent_Identity=23.6263736263736, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1786789, Length=445, Percent_Identity=23.3707865168539, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786602, Length=481, Percent_Identity=23.4927234927235, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789017, Length=352, Percent_Identity=22.4431818181818, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1790653, Length=414, Percent_Identity=22.2222222222222, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87082250, Length=473, Percent_Identity=25.5813953488372, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI2367353, Length=450, Percent_Identity=22.4444444444444, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081915, Length=427, Percent_Identity=21.0772833723653, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI48994972, Length=343, Percent_Identity=23.9067055393586, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786908, Length=393, Percent_Identity=23.9185750636132, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=406, Percent_Identity=36.4532019704434, Blast_Score=255, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI17531343, Length=417, Percent_Identity=37.6498800959233, Blast_Score=248, Evalue=5e-66,
Organism=Caenorhabditis elegans, GI17533459, Length=407, Percent_Identity=38.0835380835381, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17540018, Length=449, Percent_Identity=24.7216035634744, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71982612, Length=414, Percent_Identity=23.1884057971014, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71982608, Length=414, Percent_Identity=23.1884057971014, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193208714, Length=431, Percent_Identity=23.4338747099768, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI32566695, Length=431, Percent_Identity=23.4338747099768, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17568033, Length=435, Percent_Identity=23.448275862069, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17537453, Length=377, Percent_Identity=21.2201591511936, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI32566699, Length=347, Percent_Identity=23.9193083573487, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319991, Length=343, Percent_Identity=25.0728862973761, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24668806, Length=417, Percent_Identity=39.3285371702638, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI21356285, Length=417, Percent_Identity=39.3285371702638, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24668802, Length=417, Percent_Identity=39.3285371702638, Blast_Score=285, Evalue=3e-77,
Organism=Drosophila melanogaster, GI24666159, Length=418, Percent_Identity=37.3205741626794, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI221512776, Length=418, Percent_Identity=37.3205741626794, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24667468, Length=425, Percent_Identity=37.8823529411765, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI161077963, Length=393, Percent_Identity=37.6590330788804, Blast_Score=240, Evalue=1e-63,
Organism=Drosophila melanogaster, GI281366235, Length=410, Percent_Identity=36.5853658536585, Blast_Score=235, Evalue=6e-62,
Organism=Drosophila melanogaster, GI116007820, Length=410, Percent_Identity=36.5853658536585, Blast_Score=235, Evalue=6e-62,
Organism=Drosophila melanogaster, GI116007818, Length=410, Percent_Identity=36.5853658536585, Blast_Score=232, Evalue=5e-61,
Organism=Drosophila melanogaster, GI85725152, Length=410, Percent_Identity=36.5853658536585, Blast_Score=232, Evalue=5e-61,
Organism=Drosophila melanogaster, GI21357367, Length=440, Percent_Identity=21.1363636363636, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI221331183, Length=424, Percent_Identity=25.2358490566038, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI17647653, Length=424, Percent_Identity=25.2358490566038, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24664379, Length=424, Percent_Identity=25.2358490566038, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24651635, Length=404, Percent_Identity=24.2574257425743, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24651633, Length=404, Percent_Identity=24.2574257425743, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI45550968, Length=461, Percent_Identity=22.5596529284165, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19921172, Length=461, Percent_Identity=22.5596529284165, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50236; Mature: 50236

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCC
>Mature Secondary Structure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HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]