Click here to switch to the map view.

The map label for this gene is yvmA [H]

Identifier: 118476415

GI number: 118476415

Start: 787980

End: 789164

Strand: Reverse

Name: yvmA [H]

Synonym: BALH_0677

Alternate gene names: 118476415

Gene position: 789164-787980 (Counterclockwise)

Preceding gene: 118476422

Following gene: 118476410

Centisome position: 15.01

GC content: 33.5

Gene sequence:

>1185_bases
ATGATGAAAAAATCCAAACTACATTTCATTTTATACGTTGTCTGTATGAGTGCCTTACTCGGTTCCTTCTCTCAAAATAT
TTACACACCTATCTTACCTATGATTCAAACTTCTTTTCACACTTCTCTTTATCTTGTAAATGTAACAGTTTCACTTTTCA
CATTTGTTCTTGCGATTATGCAGCTCATATATGGACCTTTAATTGATACAAAAGGAAGAAAGTCTGTCCTTATCCCTAGT
TTAATTATTAGTACAATTGGTTCAATCGGATGTGCTTTTTCGCCGAACGTTTATTTATTTCTCTTTTTTAGAGCTGTTCA
AGCTATAGGAATAGCGGCTATACCTGTAGTTTCAGCAACGATTATTGGTGATTTGTTTGAAGGAAAAGAACGAGGAGAAG
CGATGAGCCTGTATCAAATGTTACTTGCTCTCGCACCTGCGATTGGCCCTCTCATTGGTGGTTATCTCGGCAGTATAAAT
GGCCACTTATCCGTATTTCTGTTTTTATCCATACTTGGCATCCTTTTATTAATTATAAATATTTCACTACTTCCAGAAAC
AAAACCAACTGTAATGAAACAACCGCAAGCAAAAAAGAATTACTGGCTTATCTTAAAAAATAAAACTGGATATTCTATTA
CACTTATTGGTTTCATTCAATTTTGTATTTACTTTTGCTTTCTCGTTTTTTTACCGAGCATTTTAGCAAATTCATTTCAT
CTAGCTGCAAGTGAAATTGGTCTTATCTTTGTACCAATGTCTCTTTCTATTATGATAGGAAGTTATTACTACAAGTTTTT
GCAAAAACGACTCACAACAAAGCAAGCTTTATTTATTACGAGTTTCTTCAATATTATATGTGTCGTTTTATTCTCTTTCA
CATATAGCATCAATATCCCATTCCTCATTATCGTTACATCTTTATACGGTTTTAGTATGGGACTTTCTATGCCAACTCAC
ACTACTTTATTAACAGAAGAATTTGTAAAAGAACGCGCAACAGCTATCGGTATGTACAACTTCATCCGCTATCTCGGTAT
GGGCACAGGGCCACTTGTAGGCGGATTTCTTTTATTTAATCAAAATTACTTTTGGATTTTCTTCCTAGGTGCAATTACAT
TTCTACTTATCATTTTATATGCAATGAAAATGCTACATTTTCATGCTTTACAAAAAGCAAAATAG

Upstream 100 bases:

>100_bases
CTATATACCATTTTAAAATCATTTTTTTATATTTACAAGTGAGAAAAACATGTTAAAATAAATTTAGTTTCCAAGGAAAC
TAAATTACAAGGAGGTTAAT

Downstream 100 bases:

>100_bases
AGCCCCCGAAAGGTCGGCTCTATTTTAAACTCTTTGATCCGCAACGATATGAATATCAATATGTTTCGTTTGTCTCATAA
TTTCATTTACAATCGAACCT

Product: major facilitator family transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MMKKSKLHFILYVVCMSALLGSFSQNIYTPILPMIQTSFHTSLYLVNVTVSLFTFVLAIMQLIYGPLIDTKGRKSVLIPS
LIISTIGSIGCAFSPNVYLFLFFRAVQAIGIAAIPVVSATIIGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSIN
GHLSVFLFLSILGILLLIINISLLPETKPTVMKQPQAKKNYWLILKNKTGYSITLIGFIQFCIYFCFLVFLPSILANSFH
LAASEIGLIFVPMSLSIMIGSYYYKFLQKRLTTKQALFITSFFNIICVVLFSFTYSINIPFLIIVTSLYGFSMGLSMPTH
TTLLTEEFVKERATAIGMYNFIRYLGMGTGPLVGGFLLFNQNYFWIFFLGAITFLLIILYAMKMLHFHALQKAK

Sequences:

>Translated_394_residues
MMKKSKLHFILYVVCMSALLGSFSQNIYTPILPMIQTSFHTSLYLVNVTVSLFTFVLAIMQLIYGPLIDTKGRKSVLIPS
LIISTIGSIGCAFSPNVYLFLFFRAVQAIGIAAIPVVSATIIGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSIN
GHLSVFLFLSILGILLLIINISLLPETKPTVMKQPQAKKNYWLILKNKTGYSITLIGFIQFCIYFCFLVFLPSILANSFH
LAASEIGLIFVPMSLSIMIGSYYYKFLQKRLTTKQALFITSFFNIICVVLFSFTYSINIPFLIIVTSLYGFSMGLSMPTH
TTLLTEEFVKERATAIGMYNFIRYLGMGTGPLVGGFLLFNQNYFWIFFLGAITFLLIILYAMKMLHFHALQKAK
>Mature_394_residues
MMKKSKLHFILYVVCMSALLGSFSQNIYTPILPMIQTSFHTSLYLVNVTVSLFTFVLAIMQLIYGPLIDTKGRKSVLIPS
LIISTIGSIGCAFSPNVYLFLFFRAVQAIGIAAIPVVSATIIGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSIN
GHLSVFLFLSILGILLLIINISLLPETKPTVMKQPQAKKNYWLILKNKTGYSITLIGFIQFCIYFCFLVFLPSILANSFH
LAASEIGLIFVPMSLSIMIGSYYYKFLQKRLTTKQALFITSFFNIICVVLFSFTYSINIPFLIIVTSLYGFSMGLSMPTH
TTLLTEEFVKERATAIGMYNFIRYLGMGTGPLVGGFLLFNQNYFWIFFLGAITFLLIILYAMKMLHFHALQKAK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=280, Percent_Identity=28.9285714285714, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082312, Length=358, Percent_Identity=22.0670391061453, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788509, Length=386, Percent_Identity=23.3160621761658, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790146, Length=183, Percent_Identity=25.1366120218579, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324264, Length=179, Percent_Identity=30.1675977653631, Blast_Score=87, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6322071, Length=294, Percent_Identity=27.2108843537415, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319517, Length=187, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6319657, Length=166, Percent_Identity=33.7349397590361, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322070, Length=286, Percent_Identity=26.2237762237762, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321577, Length=180, Percent_Identity=23.3333333333333, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6325414, Length=269, Percent_Identity=21.5613382899628, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44024; Mature: 44024

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKSKLHFILYVVCMSALLGSFSQNIYTPILPMIQTSFHTSLYLVNVTVSLFTFVLAIM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHH
QLIYGPLIDTKGRKSVLIPSLIISTIGSIGCAFSPNVYLFLFFRAVQAIGIAAIPVVSAT
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IIGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSINGHLSVFLFLSILGILLLIIN
HHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ISLLPETKPTVMKQPQAKKNYWLILKNKTGYSITLIGFIQFCIYFCFLVFLPSILANSFH
HHCCCCCCCHHHCCCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCHH
LAASEIGLIFVPMSLSIMIGSYYYKFLQKRLTTKQALFITSFFNIICVVLFSFTYSINIP
HHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
FLIIVTSLYGFSMGLSMPTHTTLLTEEFVKERATAIGMYNFIRYLGMGTGPLVGGFLLFN
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEE
QNYFWIFFLGAITFLLIILYAMKMLHFHALQKAK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMKKSKLHFILYVVCMSALLGSFSQNIYTPILPMIQTSFHTSLYLVNVTVSLFTFVLAIM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHH
QLIYGPLIDTKGRKSVLIPSLIISTIGSIGCAFSPNVYLFLFFRAVQAIGIAAIPVVSAT
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IIGDLFEGKERGEAMSLYQMLLALAPAIGPLIGGYLGSINGHLSVFLFLSILGILLLIIN
HHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
ISLLPETKPTVMKQPQAKKNYWLILKNKTGYSITLIGFIQFCIYFCFLVFLPSILANSFH
HHCCCCCCCHHHCCCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCHH
LAASEIGLIFVPMSLSIMIGSYYYKFLQKRLTTKQALFITSFFNIICVVLFSFTYSINIP
HHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
FLIIVTSLYGFSMGLSMPTHTTLLTEEFVKERATAIGMYNFIRYLGMGTGPLVGGFLLFN
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEE
QNYFWIFFLGAITFLLIILYAMKMLHFHALQKAK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]