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The map label for this gene is rbsK [H]

Identifier: 118476350

GI number: 118476350

Start: 703910

End: 704806

Strand: Direct

Name: rbsK [H]

Synonym: BALH_0607

Alternate gene names: 118476350

Gene position: 703910-704806 (Clockwise)

Preceding gene: 118476349

Following gene: 118476351

Centisome position: 13.39

GC content: 41.47

Gene sequence:

>897_bases
ATGCCAAATATTGCAGTAGTAGGTAGTATTTCAATGGACTTAGTGGCCGTTTCAAAAAAACGTCCGAAAGCAGGGGAAAC
AGTAATTGGTGAAGCATTTCATACAATTCCAGGAGGGAAAGGAGCTAACCAGGCGGTTGCTGCAGCTAGATTAGGCGCAA
ATGTAGCGATGGTTGGAGCAGTAGGAGACGATAATTATGGAACTGTAGTGAAGAGAAATTTAGAGAACGAACGCGTTTTT
ATCGACTATGTGGTACCGGTTACAGATGCGGCGACAGGAATTGCTCATATCGTTTTAGCAGAAGAGGATAACAGTATTGT
TGTCGTGCAAGGGGCGAATGCTCTTGTAAATGAGTCGGTTGTAGATCTTTCAAAAGATCTTCTTATAAAAGCTGATATGG
TTGTGCTTCAACTAGAGATTCCGCTTGAAACAGTAAAATATGTATTGGCTATTTGTGAGGAACACAAAATCCCGGTTATG
TTAAATCCAGCACCGGCACAAGTGTTATCAGAAGATATTTTAGAAAAGGCAACTTATATTACACCAAATGAACATGAGTG
CCGCATCGTATTAGATGATTTCACATCGCCAATTGAAGACTTACTGGCTAAATATCCGAATAAACTATTGATGACAGAAG
GTTCTAACGGTGTACGTTTCCATAATGGTACGGAGATTGTACATGTTCCTAGCATTGCTGTTGATGTAGTAGATACGACT
GGAGCTGGTGATACATTTAATGGTGCATTAGCAGTTGCGCTTTCTGAAGGAGAAACACTTCAAAAAGCAATTCGTTTTGC
GAATATTGCTGGTGGTCTTTCTGTAACGAAGCTTGGGGCGCAAGGCGGTATGCCAACGAGAGATAAAGTGCGTGAAGTGC
AGGTGATTGTTGGATGA

Upstream 100 bases:

>100_bases
TTGTTAGAGCAGATGGAAGGAAACGTATTAGAAGAGAAACACTATCGTTTACCGATTGAAATTATAGAACGAAATACAAC
GAAGTAAGGAGATGAAATAG

Downstream 100 bases:

>100_bases
AAAAGCACGGTGTATTAAATAGTGAGATTGCATCAGTCCTTGCTTCACTTGGGCATACGGATACGATTGTAATCGCTGAT
TGCGGTTTACCAATTCCTGC

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MPNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTIPGGKGANQAVAAARLGANVAMVGAVGDDNYGTVVKRNLENERVF
IDYVVPVTDAATGIAHIVLAEEDNSIVVVQGANALVNESVVDLSKDLLIKADMVVLQLEIPLETVKYVLAICEEHKIPVM
LNPAPAQVLSEDILEKATYITPNEHECRIVLDDFTSPIEDLLAKYPNKLLMTEGSNGVRFHNGTEIVHVPSIAVDVVDTT
GAGDTFNGALAVALSEGETLQKAIRFANIAGGLSVTKLGAQGGMPTRDKVREVQVIVG

Sequences:

>Translated_298_residues
MPNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTIPGGKGANQAVAAARLGANVAMVGAVGDDNYGTVVKRNLENERVF
IDYVVPVTDAATGIAHIVLAEEDNSIVVVQGANALVNESVVDLSKDLLIKADMVVLQLEIPLETVKYVLAICEEHKIPVM
LNPAPAQVLSEDILEKATYITPNEHECRIVLDDFTSPIEDLLAKYPNKLLMTEGSNGVRFHNGTEIVHVPSIAVDVVDTT
GAGDTFNGALAVALSEGETLQKAIRFANIAGGLSVTKLGAQGGMPTRDKVREVQVIVG
>Mature_297_residues
PNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTIPGGKGANQAVAAARLGANVAMVGAVGDDNYGTVVKRNLENERVFI
DYVVPVTDAATGIAHIVLAEEDNSIVVVQGANALVNESVVDLSKDLLIKADMVVLQLEIPLETVKYVLAICEEHKIPVML
NPAPAQVLSEDILEKATYITPNEHECRIVLDDFTSPIEDLLAKYPNKLLMTEGSNGVRFHNGTEIVHVPSIAVDVVDTTG
AGDTFNGALAVALSEGETLQKAIRFANIAGGLSVTKLGAQGGMPTRDKVREVQVIVG

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=293, Percent_Identity=34.4709897610922, Blast_Score=141, Evalue=6e-34,
Organism=Escherichia coli, GI1790193, Length=296, Percent_Identity=38.5135135135135, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI87082343, Length=303, Percent_Identity=28.0528052805281, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789432, Length=291, Percent_Identity=28.1786941580756, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87081971, Length=270, Percent_Identity=25.9259259259259, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788491, Length=288, Percent_Identity=23.9583333333333, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=300, Percent_Identity=35.6666666666667, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI25147470, Length=321, Percent_Identity=23.3644859813084, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319884, Length=331, Percent_Identity=32.9305135951662, Blast_Score=135, Evalue=9e-33,
Organism=Drosophila melanogaster, GI20128807, Length=300, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24583886, Length=304, Percent_Identity=27.6315789473684, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31452; Mature: 31320

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTIPGGKGANQAVAAARLGANVAMVGA
CCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEE
VGDDNYGTVVKRNLENERVFIDYVVPVTDAATGIAHIVLAEEDNSIVVVQGANALVNESV
CCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCHHHHHHH
VDLSKDLLIKADMVVLQLEIPLETVKYVLAICEEHKIPVMLNPAPAQVLSEDILEKATYI
HHHHHHHEEEEEEEEEEEECCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCC
TPNEHECRIVLDDFTSPIEDLLAKYPNKLLMTEGSNGVRFHNGTEIVHVPSIAVDVVDTT
CCCCCCEEEEECCCCCHHHHHHHHCCCEEEEECCCCCEEEECCCEEEEECCEEEEEEECC
GAGDTFNGALAVALSEGETLQKAIRFANIAGGLSVTKLGAQGGMPTRDKVREVQVIVG
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHEEEEEEEC
>Mature Secondary Structure 
PNIAVVGSISMDLVAVSKKRPKAGETVIGEAFHTIPGGKGANQAVAAARLGANVAMVGA
CCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEE
VGDDNYGTVVKRNLENERVFIDYVVPVTDAATGIAHIVLAEEDNSIVVVQGANALVNESV
CCCCCCCEEEEECCCCCEEEEEEEEECCCCCCCEEEEEEEECCCCEEEEECCCHHHHHHH
VDLSKDLLIKADMVVLQLEIPLETVKYVLAICEEHKIPVMLNPAPAQVLSEDILEKATYI
HHHHHHHEEEEEEEEEEEECCHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCC
TPNEHECRIVLDDFTSPIEDLLAKYPNKLLMTEGSNGVRFHNGTEIVHVPSIAVDVVDTT
CCCCCCEEEEECCCCCHHHHHHHHCCCEEEEECCCCCEEEECCCEEEEECCEEEEEEECC
GAGDTFNGALAVALSEGETLQKAIRFANIAGGLSVTKLGAQGGMPTRDKVREVQVIVG
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7921236; 9353933; 9384377 [H]