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The map label for this gene is citT [H]

Identifier: 118476248

GI number: 118476248

Start: 579377

End: 580069

Strand: Direct

Name: citT [H]

Synonym: BALH_0500

Alternate gene names: 118476248

Gene position: 579377-580069 (Clockwise)

Preceding gene: 118476247

Following gene: 118476250

Centisome position: 11.02

GC content: 36.51

Gene sequence:

>693_bases
ATGGGTGAGGAGATTGAAGTATTGATTGTAGAGGATGATATTCGAATTGCGGACATTCATCGTCGTTTTACTGAAAAGGT
TGAGGGGTTTAAAGTAATTGGAACAGCAACGACTGGGGAACAAGCGAAAGAATGGTTAGATCTTGTGAAACCACAGCTTG
TTTTATTAGACGTGTACTTACCTGATATGCAAGGTACGGAACTTGTTACGTATATTAGGCATCATTTACATGATACAGAT
ATTATTATGATTACAGCTGCATCGGAAACAGATGTAGTGAAGCATGCTTTACGAGGCGGAGTAACAGATTATATCGTGAA
GCCACTTATGTTTGATCGATTTAATGCAAGTTTGGAAAGTTACAAAAAAAAGATTGTGCAGTTAAAGAAAAGTAATCAAT
TATCTACAGAACAAATAGAACATTTATGGTCTCAAAGAGGCGTAAAGGGAAATGAAATAGAATATGCTCCGAAAGGAATA
GACCCTTTAACTTTAGCAAAAATAAAAAAGCATATGTTAACAGTGAATGAAGAAGGAATTACAGCAGAAATGTTAAGTGC
GATGGTAGGAGTAAGTAGGTCGACAGCGAGGCGTTATTTAGAGTATTTAATATCAGGAAAGAAAGTTCATGCAGAGCTTA
CATATGGAAGTGTGGGGAGACCAGAGAGACGGTATTTTCTTGTTTCTTCATAA

Upstream 100 bases:

>100_bases
AGTTAGTAGAAGATTTAAATGGAAGTATTGCAATCGAAAAAGGGGATTTAGGCGGCGCATTATTTATTATCGCATTACCA
AAAGAGAGAGGCGAATTGTA

Downstream 100 bases:

>100_bases
TAAAAAACAGTAGCGGATATATGTCCGCTACTGTTTTTTATTTTATATTGGAATAATCCCAATTACAATTCCAGTAATCA
ACATGACCATTGTCGTTCCA

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MGEEIEVLIVEDDIRIADIHRRFTEKVEGFKVIGTATTGEQAKEWLDLVKPQLVLLDVYLPDMQGTELVTYIRHHLHDTD
IIMITAASETDVVKHALRGGVTDYIVKPLMFDRFNASLESYKKKIVQLKKSNQLSTEQIEHLWSQRGVKGNEIEYAPKGI
DPLTLAKIKKHMLTVNEEGITAEMLSAMVGVSRSTARRYLEYLISGKKVHAELTYGSVGRPERRYFLVSS

Sequences:

>Translated_230_residues
MGEEIEVLIVEDDIRIADIHRRFTEKVEGFKVIGTATTGEQAKEWLDLVKPQLVLLDVYLPDMQGTELVTYIRHHLHDTD
IIMITAASETDVVKHALRGGVTDYIVKPLMFDRFNASLESYKKKIVQLKKSNQLSTEQIEHLWSQRGVKGNEIEYAPKGI
DPLTLAKIKKHMLTVNEEGITAEMLSAMVGVSRSTARRYLEYLISGKKVHAELTYGSVGRPERRYFLVSS
>Mature_229_residues
GEEIEVLIVEDDIRIADIHRRFTEKVEGFKVIGTATTGEQAKEWLDLVKPQLVLLDVYLPDMQGTELVTYIRHHLHDTDI
IMITAASETDVVKHALRGGVTDYIVKPLMFDRFNASLESYKKKIVQLKKSNQLSTEQIEHLWSQRGVKGNEIEYAPKGID
PLTLAKIKKHMLTVNEEGITAEMLSAMVGVSRSTARRYLEYLISGKKVHAELTYGSVGRPERRYFLVSS

Specific function: Member of the two-component regulatory system CitT/CitS. Regulates the expression of the citM-yflN operon. Phosphorylated CitT binds to the citM promoter to activate the transcription of the citM-yflN operon [H]

COG id: COG4565

COG function: function code KT; Response regulator of citrate/malate metabolism

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786838, Length=229, Percent_Identity=36.2445414847162, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1790566, Length=223, Percent_Identity=30.0448430493274, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1788550, Length=139, Percent_Identity=32.3741007194245, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788222, Length=103, Percent_Identity=32.0388349514563, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR013196
- InterPro:   IPR001789 [H]

Pfam domain/function: PF08279 HTH_11; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 26129; Mature: 25997

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEEIEVLIVEDDIRIADIHRRFTEKVEGFKVIGTATTGEQAKEWLDLVKPQLVLLDVYL
CCCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEEC
PDMQGTELVTYIRHHLHDTDIIMITAASETDVVKHALRGGVTDYIVKPLMFDRFNASLES
CCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YKKKIVQLKKSNQLSTEQIEHLWSQRGVKGNEIEYAPKGIDPLTLAKIKKHMLTVNEEGI
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCC
TAEMLSAMVGVSRSTARRYLEYLISGKKVHAELTYGSVGRPERRYFLVSS
HHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEEECC
>Mature Secondary Structure 
GEEIEVLIVEDDIRIADIHRRFTEKVEGFKVIGTATTGEQAKEWLDLVKPQLVLLDVYL
CCCEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEEC
PDMQGTELVTYIRHHLHDTDIIMITAASETDVVKHALRGGVTDYIVKPLMFDRFNASLES
CCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YKKKIVQLKKSNQLSTEQIEHLWSQRGVKGNEIEYAPKGIDPLTLAKIKKHMLTVNEEGI
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCC
TAEMLSAMVGVSRSTARRYLEYLISGKKVHAELTYGSVGRPERRYFLVSS
HHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 10972810 [H]