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The map label for this gene is trmA [C]

Identifier: 118476081

GI number: 118476081

Start: 373261

End: 374658

Strand: Direct

Name: trmA [C]

Synonym: BALH_0324

Alternate gene names: 118476081

Gene position: 373261-374658 (Clockwise)

Preceding gene: 118476076

Following gene: 118476082

Centisome position: 7.1

GC content: 40.06

Gene sequence:

>1398_bases
ATGAAAAAGAGAGGTCGGAAAATGAGTACAAAAATGACGCCACCAGTTGAAAAAAACGAGTTTATAGATGTAGTATTTGA
AGATTTAACACATGATGGTGCCGGTGTTGCGAAAGTAAAAGGCTATCCTATTTTCGTTAAAAACGGATTACCAGGTGAAG
AAGCGCAAATTAAAATTGTTAAAGTGAAGAAAAACTTCGCATTCGGTCGTTTAATGAAGCTTCATACAGAGAGCCCATAT
CGTAAAGAGGCAGAATGTCCAGTGTACAATCAGTGCGGCGGTTGTCAGCTTCAGCATTTAACATATGAAGGACAATTACA
AGCGAAAGAAAAACAAGTGCGTGACGTTATGCAGCGTATTGGCGGATTAGGTGATGTTCCTGTTCATCCTGTACTTGGCA
TGAAGAATCCGTGGATATACCGTAATAAAGCACAAGTACCAATTGGAGAACGTGAGGGCGGACTTGTAGCTGGTTTCTAT
CGTCAAGGAACGCATGACATTATTAATATGGAATCATGTTTAATTCAAGCAGAAGAAAACGATACATTGATTCAAGAAGT
AAAACGTATTTGTGAAAAACACGGTATTTCGGCGTACAACGAAGAGCGTAACAAAGGAACACTTCGTCACGTAATGGCTC
GTTACGGACAAGTAACAGGGGAAATTATGCTTGTCTTCATTACTCGTACAGCAGAACTGCCAAACAAAAAAGCAATCATT
GAAGAAATTGCCGCGAAATTCCCAGAAGTAAAATCAATTGTTCAAAACGTAAACCCGAAACGTACAAACGTAATTTTCGG
AGACAAAACGACAGTACTGTACGGATCAGAATATATTTATGACTTTATCGGCGACATTAAGTTTGCGATTTCAGCACGTT
CATTCTATCAAGTAAACCCAGAGCAAACGAAAGTGTTATACGATAAAACGTTAGAATATGCCAAATTAGATGGCAACGAA
ACAGTAATTGATGCCTATTGCGGAATTGGATCAATCTCCTTATTCCTAGCACAAAAAGCGAAAAAAGTGTACGGCGTTGA
AATTGTGCCAGAAGCAATCGAAGACGCGAAGCGTAACGCAGCGCTAAACAATATGACAAACGCTGAATTTGGCGTAGGAG
AAGCAGAAGTAGTCATTCCAAAATGGTACAAAGAAGGCGTAATCGCTGACACAATGGTCGTAGATCCACCGCGTAAAGGT
TGTGATGAGGCACTACTTAATACAATCATCGACATGAAACCAAAACGCGTCGTATATGTATCATGTAACCCAGCAACATT
AGCACGTGACTTAAAAGTACTAGAAGAAGGCGGATATAAAACGCAGGAAGTACAACCTGTTGATATGTTCCCGCATACGA
CTCATGTGGAGTGTGTAGCTTGGCTTAAGTTGGTATAA

Upstream 100 bases:

>100_bases
ATTAGTAGTAGCGTAACATTAACAGAGAACTATCGTCAATAGCTTTTTTTCTTCCAATAGAAATAGACCATATAAGTATG
ATAAAATGTAACGCAGTGTT

Downstream 100 bases:

>100_bases
TAAAAAAGCAGTTGATATAGGAAAATCTATACCATCTGCTTTTTGGTTTATTGAGAGTTTGAAATTGTATTCATAGTGAG
AGGATTTGAATTTGAAATGA

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MKKRGRKMSTKMTPPVEKNEFIDVVFEDLTHDGAGVAKVKGYPIFVKNGLPGEEAQIKIVKVKKNFAFGRLMKLHTESPY
RKEAECPVYNQCGGCQLQHLTYEGQLQAKEKQVRDVMQRIGGLGDVPVHPVLGMKNPWIYRNKAQVPIGEREGGLVAGFY
RQGTHDIINMESCLIQAEENDTLIQEVKRICEKHGISAYNEERNKGTLRHVMARYGQVTGEIMLVFITRTAELPNKKAII
EEIAAKFPEVKSIVQNVNPKRTNVIFGDKTTVLYGSEYIYDFIGDIKFAISARSFYQVNPEQTKVLYDKTLEYAKLDGNE
TVIDAYCGIGSISLFLAQKAKKVYGVEIVPEAIEDAKRNAALNNMTNAEFGVGEAEVVIPKWYKEGVIADTMVVDPPRKG
CDEALLNTIIDMKPKRVVYVSCNPATLARDLKVLEEGGYKTQEVQPVDMFPHTTHVECVAWLKLV

Sequences:

>Translated_465_residues
MKKRGRKMSTKMTPPVEKNEFIDVVFEDLTHDGAGVAKVKGYPIFVKNGLPGEEAQIKIVKVKKNFAFGRLMKLHTESPY
RKEAECPVYNQCGGCQLQHLTYEGQLQAKEKQVRDVMQRIGGLGDVPVHPVLGMKNPWIYRNKAQVPIGEREGGLVAGFY
RQGTHDIINMESCLIQAEENDTLIQEVKRICEKHGISAYNEERNKGTLRHVMARYGQVTGEIMLVFITRTAELPNKKAII
EEIAAKFPEVKSIVQNVNPKRTNVIFGDKTTVLYGSEYIYDFIGDIKFAISARSFYQVNPEQTKVLYDKTLEYAKLDGNE
TVIDAYCGIGSISLFLAQKAKKVYGVEIVPEAIEDAKRNAALNNMTNAEFGVGEAEVVIPKWYKEGVIADTMVVDPPRKG
CDEALLNTIIDMKPKRVVYVSCNPATLARDLKVLEEGGYKTQEVQPVDMFPHTTHVECVAWLKLV
>Mature_465_residues
MKKRGRKMSTKMTPPVEKNEFIDVVFEDLTHDGAGVAKVKGYPIFVKNGLPGEEAQIKIVKVKKNFAFGRLMKLHTESPY
RKEAECPVYNQCGGCQLQHLTYEGQLQAKEKQVRDVMQRIGGLGDVPVHPVLGMKNPWIYRNKAQVPIGEREGGLVAGFY
RQGTHDIINMESCLIQAEENDTLIQEVKRICEKHGISAYNEERNKGTLRHVMARYGQVTGEIMLVFITRTAELPNKKAII
EEIAAKFPEVKSIVQNVNPKRTNVIFGDKTTVLYGSEYIYDFIGDIKFAISARSFYQVNPEQTKVLYDKTLEYAKLDGNE
TVIDAYCGIGSISLFLAQKAKKVYGVEIVPEAIEDAKRNAALNNMTNAEFGVGEAEVVIPKWYKEGVIADTMVVDPPRKG
CDEALLNTIIDMKPKRVVYVSCNPATLARDLKVLEEGGYKTQEVQPVDMFPHTTHVECVAWLKLV

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=346, Percent_Identity=28.0346820809249, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI51173878, Length=346, Percent_Identity=28.0346820809249, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI269784678, Length=205, Percent_Identity=32.6829268292683, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI269784680, Length=205, Percent_Identity=32.6829268292683, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI269784676, Length=205, Percent_Identity=32.6829268292683, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI20149688, Length=205, Percent_Identity=32.6829268292683, Blast_Score=112, Evalue=5e-25,
Organism=Escherichia coli, GI1789148, Length=452, Percent_Identity=30.3097345132743, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1787083, Length=386, Percent_Identity=26.9430051813472, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1790403, Length=181, Percent_Identity=29.8342541436464, Blast_Score=76, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71997438, Length=171, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322909, Length=441, Percent_Identity=25.3968253968254, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24666579, Length=410, Percent_Identity=29.7560975609756, Blast_Score=157, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280
- InterPro:   IPR003402 [H]

Pfam domain/function: PF02475 Met_10; PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 52225; Mature: 52225

Theoretical pI: Translated: 8.13; Mature: 8.13

Prosite motif: PS50926 TRAM ; PS01230 TRMA_1 ; PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRGRKMSTKMTPPVEKNEFIDVVFEDLTHDGAGVAKVKGYPIFVKNGLPGEEAQIKIV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCEEEEEECCCCCCCCEEEEE
KVKKNFAFGRLMKLHTESPYRKEAECPVYNQCGGCQLQHLTYEGQLQAKEKQVRDVMQRI
EEECCCCHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
GGLGDVPVHPVLGMKNPWIYRNKAQVPIGEREGGLVAGFYRQGTHDIINMESCLIQAEEN
CCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCHHEEHHHHEEEECCC
DTLIQEVKRICEKHGISAYNEERNKGTLRHVMARYGQVTGEIMLVFITRTAELPNKKAII
CHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHH
EEIAAKFPEVKSIVQNVNPKRTNVIFGDKTTVLYGSEYIYDFIGDIKFAISARSFYQVNP
HHHHHHCHHHHHHHHCCCCCCCEEEECCCEEEEECCHHHHHHHCCCEEEEEECEEEEECH
EQTKVLYDKTLEYAKLDGNETVIDAYCGIGSISLFLAQKAKKVYGVEIVPEAIEDAKRNA
HHHHHHHHHCCHHEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEECHHHHHHHHHHH
ALNNMTNAEFGVGEAEVVIPKWYKEGVIADTMVVDPPRKGCDEALLNTIIDMKPKRVVYV
HHCCCCCCCCCCCCEEEEECCHHCCCCEECEEEECCCCCCHHHHHHHHHHCCCCCEEEEE
SCNPATLARDLKVLEEGGYKTQEVQPVDMFPHTTHVECVAWLKLV
ECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKKRGRKMSTKMTPPVEKNEFIDVVFEDLTHDGAGVAKVKGYPIFVKNGLPGEEAQIKIV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCEEEEEECCCCCCCCEEEEE
KVKKNFAFGRLMKLHTESPYRKEAECPVYNQCGGCQLQHLTYEGQLQAKEKQVRDVMQRI
EEECCCCHHHHHEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHH
GGLGDVPVHPVLGMKNPWIYRNKAQVPIGEREGGLVAGFYRQGTHDIINMESCLIQAEEN
CCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCHHEEHHHHEEEECCC
DTLIQEVKRICEKHGISAYNEERNKGTLRHVMARYGQVTGEIMLVFITRTAELPNKKAII
CHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHH
EEIAAKFPEVKSIVQNVNPKRTNVIFGDKTTVLYGSEYIYDFIGDIKFAISARSFYQVNP
HHHHHHCHHHHHHHHCCCCCCCEEEECCCEEEEECCHHHHHHHCCCEEEEEECEEEEECH
EQTKVLYDKTLEYAKLDGNETVIDAYCGIGSISLFLAQKAKKVYGVEIVPEAIEDAKRNA
HHHHHHHHHCCHHEECCCCCEEEEECCCCCHHHHHHHHHHHHHCCEEECHHHHHHHHHHH
ALNNMTNAEFGVGEAEVVIPKWYKEGVIADTMVVDPPRKGCDEALLNTIIDMKPKRVVYV
HHCCCCCCCCCCCCEEEEECCHHCCCCEECEEEECCCCCCHHHHHHHHHHCCCCCEEEEE
SCNPATLARDLKVLEEGGYKTQEVQPVDMFPHTTHVECVAWLKLV
ECCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA