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The map label for this gene is pbuG [H]

Identifier: 118476025

GI number: 118476025

Start: 283788

End: 285113

Strand: Direct

Name: pbuG [H]

Synonym: BALH_0264

Alternate gene names: 118476025

Gene position: 283788-285113 (Clockwise)

Preceding gene: 118476024

Following gene: 118476026

Centisome position: 5.4

GC content: 40.27

Gene sequence:

>1326_bases
ATGAAACGCTATTTTCAGTTTGATGAACTCGGCACGAATTATAAAACAGAGTTCATAGCAGGTTTAACGACATTTTTATC
TATGGCGTATGTGCTATTTGTCAATCCTGCTACGCTGTCACTTGGAAATGTTAAAGGGTTACCGGCAGGCACAGGAATGG
ATCCAGGTGCAGTATTCGTTGCTACAGCATTAGCAGCAGCGATCGGTTCGTTAATTATGGGTATTTTCGCAAAGTATCCG
ATTGCTTTAGCGCCAGGTATGGGAATTAACGCGTTCTTTGCTTATACAGCAGTGTTAACGATGGGTATTCCGTGGCAAAC
AGCAATTGCTGGAACGTTAATGTCAGGTATTATTTTTATTATTCTTACTGCTTCAGGTATTCGTGAAAAAATCATTAACG
CAATTCCATCAGAGTTAAAGTTCGCAGTAGCGGCAGGTATCGGATTATTCATAGCATTCCTTGGATTCCAAAATGCCGGG
ATTATCGTGAAAAATGATGCTGTCCTTGTTGGGTTGGGGGATTTAACAAAGGGCACAACGTTACTAGCAATCTTCGGAGT
TGTTACGACAATCATCTTCATGATTAAGAAAGTTAATGGTGCAGTGTTCTACGGTATGATTCTTACAGCAATATTAGGAG
TAGCAACAGGATTAATTGATACTCCAAAAGCTGTAGTGGGAGCAATCCCGAGTCTAGAACCAACGTTCGGTGCAGCGTTA
ACGCACTTCGGAGATATTTTCACTGTTCAAATGGGGATTGTTATTATAACGTTCTTCTTTATCGATTTCTTTGATACAGC
AGGTACACTTGTAGCGGTTGCGAATCAAGCAGGATTAATGAAGAACAATAAATTACCACGTGCAGGAAAAGCGTTATTTG
CAGATGCAATTGCAACTGTAATCGGTGCGATCTTAGGTACATCAACAACAACATCTTACATTGAGTCGTCTGCAGGGGTA
GCGGCAGGTGGACGTTCTGGTTTTACAGCAGTTGTAACAGCAGGATTCTTCTTACTGGCACTATTCTTCTCGCCATTATT
AAGTGTTGTAACACCAGCTGTAACGGCACCAGCTTTAATTATTGTAGGGATCTTGATGGTTTCATCTTTAGGAGAAATTG
ATTGGAAGAAATTCGAGATTGCAGTACCGGCGTTCTTTACTATCATTTCAATGCCGCTTACGTATAGTATCGCAACGGGA
ATTGCGATTGGGTTTATTTTCTATCCAATTACAATGGTAGTAAGTGGTCGACGTAAAGAGATTCATCCAATTATGTATGT
TATGGGAGTTTTATTCGTACTATATTTCATCTACGTTCGTAAATAA

Upstream 100 bases:

>100_bases
CGCTTCCATGTATATGCAATGGAAGCCTTTTTTATTTTTAATAAATAAAAGAGGGCTAGGGGAATTACGGCGAGTAATCA
TATAACGGGGGAAACGTAAG

Downstream 100 bases:

>100_bases
AAGGGGTTTTTTGAAAGGTCTAGACTTAAGGGGAGTCTAGACCTTTTTTGCGTCTTCAGAAAAACTTAAGGATTTCCGAG
CGTTTTTCTTCAGAAGTTTT

Product: guanine-hypoxanthine permease, xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNVKGLPAGTGMDPGAVFVATALAAAIGSLIMGIFAKYP
IALAPGMGINAFFAYTAVLTMGIPWQTAIAGTLMSGIIFIILTASGIREKIINAIPSELKFAVAAGIGLFIAFLGFQNAG
IIVKNDAVLVGLGDLTKGTTLLAIFGVVTTIIFMIKKVNGAVFYGMILTAILGVATGLIDTPKAVVGAIPSLEPTFGAAL
THFGDIFTVQMGIVIITFFFIDFFDTAGTLVAVANQAGLMKNNKLPRAGKALFADAIATVIGAILGTSTTTSYIESSAGV
AAGGRSGFTAVVTAGFFLLALFFSPLLSVVTPAVTAPALIIVGILMVSSLGEIDWKKFEIAVPAFFTIISMPLTYSIATG
IAIGFIFYPITMVVSGRRKEIHPIMYVMGVLFVLYFIYVRK

Sequences:

>Translated_441_residues
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNVKGLPAGTGMDPGAVFVATALAAAIGSLIMGIFAKYP
IALAPGMGINAFFAYTAVLTMGIPWQTAIAGTLMSGIIFIILTASGIREKIINAIPSELKFAVAAGIGLFIAFLGFQNAG
IIVKNDAVLVGLGDLTKGTTLLAIFGVVTTIIFMIKKVNGAVFYGMILTAILGVATGLIDTPKAVVGAIPSLEPTFGAAL
THFGDIFTVQMGIVIITFFFIDFFDTAGTLVAVANQAGLMKNNKLPRAGKALFADAIATVIGAILGTSTTTSYIESSAGV
AAGGRSGFTAVVTAGFFLLALFFSPLLSVVTPAVTAPALIIVGILMVSSLGEIDWKKFEIAVPAFFTIISMPLTYSIATG
IAIGFIFYPITMVVSGRRKEIHPIMYVMGVLFVLYFIYVRK
>Mature_441_residues
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNVKGLPAGTGMDPGAVFVATALAAAIGSLIMGIFAKYP
IALAPGMGINAFFAYTAVLTMGIPWQTAIAGTLMSGIIFIILTASGIREKIINAIPSELKFAVAAGIGLFIAFLGFQNAG
IIVKNDAVLVGLGDLTKGTTLLAIFGVVTTIIFMIKKVNGAVFYGMILTAILGVATGLIDTPKAVVGAIPSLEPTFGAAL
THFGDIFTVQMGIVIITFFFIDFFDTAGTLVAVANQAGLMKNNKLPRAGKALFADAIATVIGAILGTSTTTSYIESSAGV
AAGGRSGFTAVVTAGFFLLALFFSPLLSVVTPAVTAPALIIVGILMVSSLGEIDWKKFEIAVPAFFTIISMPLTYSIATG
IAIGFIFYPITMVVSGRRKEIHPIMYVMGVLFVLYFIYVRK

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=446, Percent_Identity=42.152466367713, Blast_Score=335, Evalue=5e-93,
Organism=Escherichia coli, GI1790150, Length=440, Percent_Identity=41.1363636363636, Blast_Score=322, Evalue=4e-89,
Organism=Escherichia coli, GI1790499, Length=446, Percent_Identity=34.5291479820628, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI48994909, Length=431, Percent_Identity=33.1786542923434, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 46308; Mature: 46308

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNVKGLPAGTGMDPGAVFV
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHH
ATALAAAIGSLIMGIFAKYPIALAPGMGINAFFAYTAVLTMGIPWQTAIAGTLMSGIIFI
HHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ILTASGIREKIINAIPSELKFAVAAGIGLFIAFLGFQNAGIIVKNDAVLVGLGDLTKGTT
HHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCCCCCHH
LLAIFGVVTTIIFMIKKVNGAVFYGMILTAILGVATGLIDTPKAVVGAIPSLEPTFGAAL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHH
THFGDIFTVQMGIVIITFFFIDFFDTAGTLVAVANQAGLMKNNKLPRAGKALFADAIATV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
IGAILGTSTTTSYIESSAGVAAGGRSGFTAVVTAGFFLLALFFSPLLSVVTPAVTAPALI
HHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVGILMVSSLGEIDWKKFEIAVPAFFTIISMPLTYSIATGIAIGFIFYPITMVVSGRRKE
HHHHHHHHHCCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IHPIMYVMGVLFVLYFIYVRK
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKRYFQFDELGTNYKTEFIAGLTTFLSMAYVLFVNPATLSLGNVKGLPAGTGMDPGAVFV
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCHHHHH
ATALAAAIGSLIMGIFAKYPIALAPGMGINAFFAYTAVLTMGIPWQTAIAGTLMSGIIFI
HHHHHHHHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
ILTASGIREKIINAIPSELKFAVAAGIGLFIAFLGFQNAGIIVKNDAVLVGLGDLTKGTT
HHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEECCCCCCCHH
LLAIFGVVTTIIFMIKKVNGAVFYGMILTAILGVATGLIDTPKAVVGAIPSLEPTFGAAL
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHH
THFGDIFTVQMGIVIITFFFIDFFDTAGTLVAVANQAGLMKNNKLPRAGKALFADAIATV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
IGAILGTSTTTSYIESSAGVAAGGRSGFTAVVTAGFFLLALFFSPLLSVVTPAVTAPALI
HHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVGILMVSSLGEIDWKKFEIAVPAFFTIISMPLTYSIATGIAIGFIFYPITMVVSGRRKE
HHHHHHHHHCCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
IHPIMYVMGVLFVLYFIYVRK
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377; 11591660 [H]