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The map label for this gene is pnuC [H]

Identifier: 118475963

GI number: 118475963

Start: 207541

End: 208251

Strand: Direct

Name: pnuC [H]

Synonym: BALH_0198

Alternate gene names: 118475963

Gene position: 207541-208251 (Clockwise)

Preceding gene: 118475958

Following gene: 118475965

Centisome position: 3.95

GC content: 31.08

Gene sequence:

>711_bases
ATGAAAAGTAGGAAATTAATGGTGAAAGGGAATTTATTACACATCTGGGGAGAGATGATTATGATTAGAAGTCCGCTCTT
TTTACTCATTACTAGTATTATTTGTGTATTGGTTGGATTGTATATTCAATCGAGCTATATTGAAATCTTTGCATCGGTCA
TGGGAATTATTAATGTTTGGCTATTAGCAAGAGAAAAAGTATCCAACTTTTTATTCGGTATGATTACCGTTGCGGTATTT
CTATATATTTTTATTACACAAGGTTTATATGCAATGGCAGTATTGGCAGCCTTTCAATTTATATTTAATGTATATGGTGG
GTATCATTGGATTGCACGTAGTGGGGAGGAAGAGGTAAAAGCAACAGTTCGTTTAGATTTGAAAGGTTGGATTTTTTATA
TAATCTTTATTTTAGTTGCATGTATTGGTTGGGGGTATTATCAAGTCCATTACTTAGAATCAACAAGTCCATATTTAGAC
GCTTTAAATGCTGTACTAGGATTAGTAGCTCAATTTATGCTAAGTCGAAAAATCTTAGAAAACTGGTATTTATGGATTTT
ATATAATGTAGTTAGTATTTCAATTTATATTTCCACTGGGTTATACGTTATGCTAATATTAGCTGTTATTAATCTCTTTA
TATGTGTAGCGGGTTTGCTAGAGTGGAAGAATAATTATAAGGGACAAAAACATACAAATAATTATATCTAG

Upstream 100 bases:

>100_bases
TATCCTCTATTCCTTTCTAGTGGAGATATGTTATAAAAAACGATACCATTTTTAAGAGAATTTTGTAAAAAGAAAAGGCT
TATTGTAGATGGAATAGATA

Downstream 100 bases:

>100_bases
AAAATAAATAGAATTAAAAAACCCCTGAAGCATATGTGCCTCAGGGGTTTACTAATAGATTATAAGTTTATGCTTTTGTC
ATACCAAGTAATACAGCGCC

Product: nicotinamide mononucleotide transporter

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKSRKLMVKGNLLHIWGEMIMIRSPLFLLITSIICVLVGLYIQSSYIEIFASVMGIINVWLLAREKVSNFLFGMITVAVF
LYIFITQGLYAMAVLAAFQFIFNVYGGYHWIARSGEEEVKATVRLDLKGWIFYIIFILVACIGWGYYQVHYLESTSPYLD
ALNAVLGLVAQFMLSRKILENWYLWILYNVVSISIYISTGLYVMLILAVINLFICVAGLLEWKNNYKGQKHTNNYI

Sequences:

>Translated_236_residues
MKSRKLMVKGNLLHIWGEMIMIRSPLFLLITSIICVLVGLYIQSSYIEIFASVMGIINVWLLAREKVSNFLFGMITVAVF
LYIFITQGLYAMAVLAAFQFIFNVYGGYHWIARSGEEEVKATVRLDLKGWIFYIIFILVACIGWGYYQVHYLESTSPYLD
ALNAVLGLVAQFMLSRKILENWYLWILYNVVSISIYISTGLYVMLILAVINLFICVAGLLEWKNNYKGQKHTNNYI
>Mature_236_residues
MKSRKLMVKGNLLHIWGEMIMIRSPLFLLITSIICVLVGLYIQSSYIEIFASVMGIINVWLLAREKVSNFLFGMITVAVF
LYIFITQGLYAMAVLAAFQFIFNVYGGYHWIARSGEEEVKATVRLDLKGWIFYIIFILVACIGWGYYQVHYLESTSPYLD
ALNAVLGLVAQFMLSRKILENWYLWILYNVVSISIYISTGLYVMLILAVINLFICVAGLLEWKNNYKGQKHTNNYI

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786965, Length=210, Percent_Identity=29.0476190476191, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 27181; Mature: 27181

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRKLMVKGNLLHIWGEMIMIRSPLFLLITSIICVLVGLYIQSSYIEIFASVMGIINVW
CCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAREKVSNFLFGMITVAVFLYIFITQGLYAMAVLAAFQFIFNVYGGYHWIARSGEEEVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHH
ATVRLDLKGWIFYIIFILVACIGWGYYQVHYLESTSPYLDALNAVLGLVAQFMLSRKILE
HHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
NWYLWILYNVVSISIYISTGLYVMLILAVINLFICVAGLLEWKNNYKGQKHTNNYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKSRKLMVKGNLLHIWGEMIMIRSPLFLLITSIICVLVGLYIQSSYIEIFASVMGIINVW
CCCCCEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLAREKVSNFLFGMITVAVFLYIFITQGLYAMAVLAAFQFIFNVYGGYHWIARSGEEEVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHH
ATVRLDLKGWIFYIIFILVACIGWGYYQVHYLESTSPYLDALNAVLGLVAQFMLSRKILE
HHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHH
NWYLWILYNVVSISIYISTGLYVMLILAVINLFICVAGLLEWKNNYKGQKHTNNYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2198247; 11677609 [H]